{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T21:52:31Z","timestamp":1773352351688,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"NO FUNDING"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"DOI":"10.1007\/s00277-025-06566-w","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T01:52:16Z","timestamp":1765331536000},"page":"6395-6401","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adapting haematology practices for effective management of blood disorders in pregnancy in a limited resource setting"],"prefix":"10.1007","volume":"104","author":[{"given":"Thushara","family":"Balasuriya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chitranga C.","family":"Kariyawasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"issue":"2","key":"6566_CR1","first-page":"177","volume":"64","author":"World Health Organization","year":"2022","unstructured":"World Health Organization (2022) Sri Lanka: Situat Rep 64(2):177\u2013186. https:\/\/genderdata.worldbank.org\/en\/economies\/sri-lanka","journal-title":"Sri Lanka: Situat Rep"},{"key":"6566_CR2","doi-asserted-by":"publisher","unstructured":"Paradkar MN, Mejia I, Abraheem R, Marroqu\u00edn Le\u00f3n E, Firdous A, Barroso MJ. Assessing the Impact of Hematological Changes in Pregnancy on Maternal and Fetal Death: A Narrative Review. Cureus. 16 202 10.7759\/cureus.66982 https:\/\/doi.org\/10.7759\/cureus.66982","DOI":"10.7759\/cureus.66982"},{"key":"6566_CR3","doi-asserted-by":"crossref","unstructured":"James AH, Pacheco LD, Konkle BA Hematologists and the care of pregnant women management of preg Nant women who have bleed Ing dis or Ders.: http:\/\/ashpublications.org\/hematology\/article-pdf\/2023\/1\/229\/2175618\/229james.pdf","DOI":"10.1182\/hematology.2023000475"},{"issue":"3","key":"6566_CR4","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1007\/s12288-012-0175-6","volume":"28","author":"S Chandra","year":"2012","unstructured":"Chandra S, Tripathi AK, Mishra S, Amzarul M, Vaish AK (2012) Physiological changes in hematological parameters during pregnancy. Indian J Hematol Blood Transfus 28(3):144\u2013146. https:\/\/doi.org\/10.1007\/s12288-012-0175-6","journal-title":"Indian J Hematol Blood Transfus"},{"issue":"3","key":"6566_CR5","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1053\/j.seminhematol.2013.06.004","volume":"50","author":"M Danielle","year":"2013","unstructured":"Danielle M (2013) Townsley. Hematologic complications of pregnancy. Semin Hematol 50(3):222\u2013231. https:\/\/doi.org\/10.1053\/j.seminhematol.2013.06.004","journal-title":"Semin Hematol"},{"issue":"6","key":"6566_CR6","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.bpobgyn.2013.08.002","volume":"27","author":"MBC Koh","year":"2013","unstructured":"Koh MBC, Lao ZT, Rhodes E (2013) Managing haematological disorders during pregnancy. Best Pract Res Clin Obstet Gynaecol 27(6):855\u2013865. https:\/\/doi.org\/10.1016\/j.bpobgyn.2013.08.002","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"2","key":"6566_CR7","doi-asserted-by":"publisher","first-page":"89","DOI":"10.5830\/CVJA-2016-021","volume":"27","author":"P Soma-Pillay","year":"2016","unstructured":"Soma-Pillay P, Nelson-Piercy C, Tolppanen H, Mebazaa A (2016) Physiological changes in pregnancy. Cardiovasc J Afr 27(2):89\u201394. https:\/\/doi.org\/10.5830\/CVJA-2016-021","journal-title":"Cardiovasc J Afr"},{"key":"6566_CR8","unstructured":"Development F, Adaptation M (2025) Maternal Physiological Changes in Pregnancy. 1\u201326. https:\/\/www.glowm.com\/article\/heading\/vol-4--fetal-development-and-maternal-adaptation--maternal-physiological-changes-in-pregnancy\/id\/411323"},{"issue":"4","key":"6566_CR9","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s10928-020-09677-1","volume":"47","author":"M Anker, Jamil","year":"2020","unstructured":"Anker, Jamil M, van den KazmaJohn KA (2020) Anatomical and physiological alterations of pregnancy HHS public access. J Pharmacokinet Pharmacodyn 47(4):271\u2013285. https:\/\/doi.org\/10.1007\/s10928-020-09677-1","journal-title":"J Pharmacokinet Pharmacodyn"},{"issue":"3","key":"6566_CR10","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1002\/bdrc.21111","volume":"105","author":"W Evi Struble","year":"2015","unstructured":"Evi Struble W, Harrouk A, DeFelice BT (2015) Nonclinical aspects of venous thrombosis in pregnancy HHS public access. Birth Defects Res C Embryo Today 105(3):190\u2013200. https:\/\/doi.org\/10.1002\/bdrc.21111","journal-title":"Birth Defects Res C Embryo Today"},{"issue":"2","key":"6566_CR11","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/ejh.13250","volume":"103","author":"G Castaman","year":"2019","unstructured":"Castaman G, James PD (2019) Pregnancy and delivery in women with von Willebrand disease. Eur J Haematol 103(2):73\u201379. https:\/\/doi.org\/10.1111\/ejh.13250","journal-title":"Eur J Haematol"},{"issue":"2","key":"6566_CR12","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1055\/s-2003-38833","volume":"29","author":"N Lanir","year":"2003","unstructured":"Lanir N, Aharon A, Brenner B (2003) Procoagulant and anticoagulant mechanisms in human placenta. Semin Thromb Hemost 29(2):175\u2013183. https:\/\/doi.org\/10.1055\/s-2003-38833","journal-title":"Semin Thromb Hemost"},{"issue":"21","key":"6566_CR13","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1182\/blood-2017-05-781971","volume":"130","author":"DB Cines","year":"2017","unstructured":"Cines DB, Levine LD (2017) Thrombocytopenia in pregnancy. Blood 130(21):2271\u20132277. https:\/\/doi.org\/10.1182\/blood-2017-05-781971","journal-title":"Blood"},{"issue":"15","key":"6566_CR14","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1182\/blood.2023021925","volume":"143","author":"Z Yang","year":"2024","unstructured":"Yang Z, Hu L, Zhen J, Gu Y, Liu Y, Huang S (2024) Genetic basis of pregnancy-associated decreased platelet counts and gestational thrombocytopenia. Blood 143(15):1528\u20131538. https:\/\/doi.org\/10.1182\/blood.2023021925","journal-title":"Blood"},{"key":"6566_CR15","doi-asserted-by":"publisher","unstructured":"Thachil J, Owusu-Ofori S, Bates I (2013) Haematological Diseases in the Tropics. A Checklist for Clinicians. Twenty Thi. Manson\u2019s Tropical Diseases: Twenty-Third Edition. 894\u2013932 https:\/\/doi.org\/10.1016\/B978-0-7020-5101-2.00066-2","DOI":"10.1016\/B978-0-7020-5101-2.00066-2"},{"issue":"S1","key":"6566_CR16","doi-asserted-by":"publisher","first-page":"79","DOI":"10.5045\/br.2022.2022068","volume":"57","author":"YH Park","year":"2022","unstructured":"Park YH (2022) Diagnosis and management of thrombocytopenia in pregnancy. Blood Res 57(S1):79\u201385. https:\/\/doi.org\/10.5045\/br.2022.2022068","journal-title":"Blood Res"},{"issue":"3","key":"6566_CR17","doi-asserted-by":"publisher","first-page":"61","DOI":"10.4038\/sljog.v36i3.7713","volume":"36","author":"TS Palihawadana","year":"2014","unstructured":"Palihawadana TS, Goonewardene IMR, Motha MBC, Williams HSA (2014) Iron deficiency anaemia in pregnancy: diagnosis, prevention and treatment. Sri Lanka J Obstet Gynaecol 36(3):61. https:\/\/doi.org\/10.4038\/sljog.v36i3.7713","journal-title":"Sri Lanka J Obstet Gynaecol"},{"issue":"4","key":"6566_CR18","doi-asserted-by":"publisher","first-page":"256","DOI":"10.4038\/cmj.v62i3.8521","volume":"62","author":"D Senadheera","year":"2017","unstructured":"Senadheera D, Goonewardene M, Mampitiya I (2017) Authors response: Anaemia and iron deficiency in pregnant women attending an antenatal clinic in a teaching hospital in Southern Sri Lanka. Ceylon Med J 62(4):256. https:\/\/doi.org\/10.4038\/cmj.v62i3.8521","journal-title":"Ceylon Med J"},{"issue":"1","key":"6566_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12884-021-04341-z","volume":"22","author":"GS Amarasinghe","year":"2022","unstructured":"Amarasinghe GS, Agampodi TC, Mendis V, Malawanage K, Kappagoda C, Agampodi SB (2022) Prevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies. BMC Pregnancy Childbirth 22(1):1\u201312. https:\/\/doi.org\/10.1186\/s12884-021-04341-z","journal-title":"BMC Pregnancy Childbirth"},{"key":"6566_CR20","doi-asserted-by":"publisher","unstructured":"Hewawaduge D, Wijesekara J, Lekamge K, Abeygunawardhana L, Lokuyaddage SSK, De Silva BSS (2019) Knowledge about iron deficiency anemia among pregnant mothers in the first trimester in Sri Lanka. 2(Mcv):1\u20139. https:\/\/doi.org\/10.17501\/26138417.2019.2101","DOI":"10.17501\/26138417.2019.2101"},{"issue":"2","key":"6566_CR21","doi-asserted-by":"publisher","first-page":"146","DOI":"10.15537\/smj.2015.2.10289","volume":"36","author":"NM Abu-Ouf","year":"2015","unstructured":"Abu-Ouf NM, Jan MM (2015) The impact of maternal iron deficiency and iron deficiency anemia on child\u2019s health. Saudi Med J 36(2):146\u2013149. https:\/\/doi.org\/10.15537\/smj.2015.2.10289","journal-title":"Saudi Med J"},{"key":"6566_CR22","unstructured":"RCOG Green-top Guideline. Royal College of Obstetricians and Gynaecologists. Thromboembolic Disease in Pregnancy and the Puerperium: Acute Management (Green-top Guideline No. 37b) (2015) ;(37). https:\/\/www.rcog.org.uk\/globalassets\/documents\/guidelines\/gtg-37b.pdf"},{"key":"6566_CR23","doi-asserted-by":"publisher","unstructured":"Alsheef MA, Alabbad AM, Albassam RA, Alarfaj RM, Zaidi ARZ, Al-Arfaj O (2020) Pregnancy and Venous Thromboembolism: Risk Factors, Trends, Management, and Mortality. Biomed Res Int. ;2020. https:\/\/doi.org\/10.1155\/2020\/4071892","DOI":"10.1155\/2020\/4071892"},{"issue":"February","key":"6566_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmolb.2020.00016","volume":"7","author":"F Sorrentino","year":"2020","unstructured":"Sorrentino F, Maffei L, Caprari P, Cassetta R, Dell\u2019anna D, Materazzi S (2020) Pregnancy in thalassemia and sickle cell disease: the experience of an Italian thalassemia center. Front Mol Biosci 7(February):1\u20136. https:\/\/doi.org\/10.3389\/fmolb.2020.00016","journal-title":"Front Mol Biosci"},{"issue":"6","key":"6566_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7759\/cureus.41165","volume":"15","author":"T Shegekar","year":"2023","unstructured":"Shegekar T, Pajai S (2023) A comprehensive review of pregnancy in sickle cell disease. Cureus 15(6):1\u201312. https:\/\/doi.org\/10.7759\/cureus.41165","journal-title":"Cureus"},{"key":"6566_CR26","unstructured":"Royal College of Obstetricians & Gynaecologists (2014) Management of beta thalassaemia in pregnancy. R Coll Obstet Gynaecol. (66):1\u201317. https:\/\/www.rcog.org.uk\/media\/vz1g54xu\/gtg_66_thalassaemia.pdf"},{"issue":"1","key":"6566_CR27","doi-asserted-by":"publisher","first-page":"5","DOI":"10.5005\/jp-journals-10065-0002","volume":"1","author":"T Banerjee","year":"2017","unstructured":"Banerjee T, Aniyery RB (2017) Thalassemia and its management during pregnancy. World Journal of Anemia 1(1):5\u201317","journal-title":"World Journal of Anemia"},{"key":"6566_CR28","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2019.019","author":"R Origa","year":"2019","unstructured":"Origa R, Comitini F (2019) Pregnancy in thalassemia. Mediterr J Hematol Infect Dis. https:\/\/doi.org\/10.4084\/MJHID.2019.019","journal-title":"Mediterr J Hematol Infect Dis"},{"issue":"10","key":"6566_CR29","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1038\/s41375-022-01688-w","volume":"36","author":"AR Landtblom","year":"2022","unstructured":"Landtblom AR, Andersson TML, Johansson ALV, Wendel SB, Lundberg FE, Samuelsson J (2022) Pregnancy and childbirth outcomes in women with myeloproliferative neoplasms\u2014a nationwide population-based study of 342 pregnancies in Sweden. Leukemia 36(10):2461\u20132467. https:\/\/doi.org\/10.1038\/s41375-022-01688-w","journal-title":"Leukemia"},{"issue":"3","key":"6566_CR30","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1002\/ajh.26067","volume":"96","author":"N Gangat","year":"2021","unstructured":"Gangat N, Tefferi A (2021) Myeloproliferative neoplasms and pregnancy: overview and practice recommendations. Am J Hematol 96(3):354\u2013366. https:\/\/doi.org\/10.1002\/ajh.26067","journal-title":"Am J Hematol"},{"key":"6566_CR31","doi-asserted-by":"publisher","unstructured":"Scheres LJJ, Marijnen MC, Middeldorp S (2017) Aspirin or heparin or both for improving pregnancy outcomes in women with persistent antiphospholipid antibodies and recurrent pregnancy loss. Cochrane Database Syst Rev 2017(11). https:\/\/doi.org\/10.1002\/14651858.CD012852.pub2","DOI":"10.1002\/14651858.CD012852.pub2"},{"key":"6566_CR32","doi-asserted-by":"publisher","unstructured":"Dudley L, Mp G, S GM, Ad O, Marti S, Ad O (2017) Implementation strategies for health systems in low-income countries;an overview of systematic reviews (Review). https:\/\/doi.org\/10.1002\/14651858.CD011086.pub2","DOI":"10.1002\/14651858.CD011086.pub2"},{"key":"6566_CR33","unstructured":"WHO. Trends in maternal mortality 2000 to 2020: estimates. WHO, Geneva (2021) 12 https:\/\/www.who.int\/reproductivehealth\/publications\/maternal-mortality-2000-2017\/en\/https:\/\/www.unfpa.org\/sites\/default\/files\/pub-pdf\/9789240108462-eng.pdf"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-025-06566-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-025-06566-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-025-06566-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:15:16Z","timestamp":1767485716000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-025-06566-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":33,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["6566"],"URL":"https:\/\/doi.org\/10.1007\/s00277-025-06566-w","relation":{},"ISSN":["1432-0584"],"issn-type":[{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,10]]},"assertion":[{"value":"20 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors consented to the publication of this research article. Written informed consent for publication was obtained from all study patients, and the research adhered to ethical guidelines. The data presented are novel and have not been published elsewhere.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish\u00a0"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}