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Sequencing analysis of the oral mucosa and bone marrow specimens during the remission phase confirmed the germline origin of the\n                    <jats:italic>TET2<\/jats:italic>\n                    mutation. This represents the first documented case of the sequential transformation across three distinct lymphoid malignancies attributable to a germline\n                    <jats:italic>TET2<\/jats:italic>\n                    mutation, underscoring its pivotal role in lymphomagenesis and clonal evolution.\n                  <\/jats:p>","DOI":"10.1007\/s00277-026-06930-4","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:09:13Z","timestamp":1773767353000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["TET2 germline mutation in a patient with sequential lymphoid malignancies: a novel case report"],"prefix":"10.1007","volume":"105","author":[{"given":"Xia","family":"Mao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kefeng","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qilin","family":"Ao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"issue":"22","key":"6930_CR1","doi-asserted-by":"publisher","first-page":"2289","DOI":"10.1056\/NEJMoa0810069","volume":"360","author":"F Delhommeau","year":"2009","unstructured":"Delhommeau F, Dupont S, Della Valle V et al (2009) Mutation in TET2 in myeloid cancers. 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The patients\/participants provided their written informed consent to participate in this study. Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}}],"article-number":"184"}}