{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:56:49Z","timestamp":1781647009718,"version":"3.54.5"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012681","name":"Universit\u00e4tsklinikum K\u00f6ln","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012681","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Hematol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment, which carries a high risk of complications and mortality, highlighting the necessity of discussions about life threat. This study explores the perspectives of patients, informal caregivers (ICs), and healthcare professionals (HCPs) regarding the timing, content, and challenges of these discussions. Multicenter cross-sectional survey in comprehensive care centers across Germany, involving patients with allo-HSCT, ICs, and HCPs. Questionnaires assessed perceived concerns about life threat, communication needs, and attitudes toward death. Statistical analyses included descriptive statistics, group comparisons, and multivariate logistic regressions. A total of 61 patients, 31 ICs and 125 HCPs participated in this study. Patients and ICs had a high need for discussion about life threat at diagnosis, which was corroborated by HCPs. At further time points in the transplant trajectory, there were more discrepancies between patients\u2018\/ICs\u2018 and HCPs\u2019 perceptions towards conversations about life threat. While 61.7% of patients preferred having their ICs present during discussions, ICs often felt overlooked, with only 50% finding conversations with HCPs helpful. HCPs\u2019 avoidance of death was associated with a reduced likelihood of reporting a need for conversation in patients in the event of severe complications. These findings highlight a discrepancy between patients\u2019 and ICs\u2019 preferred timing for conversations about life threat and HCPs\u2019 perceptions of when patients actually express such a need. To bridge this gap, earlier and ongoing conversations are essential. Training programs should address HCPs\u2019 discomfort in discussing prognosis and improve interdisciplinary teamwork to standardize end-of-life communication.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial registration number<\/jats:bold>\n                    : DRKS00027290 (German Clinical Trials Register) on 10.01.2022.\n                  <\/jats:p>","DOI":"10.1007\/s00277-026-06981-7","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T13:06:05Z","timestamp":1775135165000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["How to talk about death? A cross-sectional survey on patients\u2019, informal caregivers\u2019 and health care professionals\u2019 views in the setting of allogenic hematopoietic stem cell transplantation"],"prefix":"10.1007","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0402-8197","authenticated-orcid":false,"given":"Lisanne","family":"Preuss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6884-1813","authenticated-orcid":false,"given":"Steffen T.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7473-7476","authenticated-orcid":false,"given":"Marco","family":"Herling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5543-0257","authenticated-orcid":false,"given":"Udo","family":"Holtick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1618-8784","authenticated-orcid":false,"given":"Alinda","family":"Reimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-6659","authenticated-orcid":false,"given":"Berenike","family":"Schoerger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6252-6193","authenticated-orcid":false,"given":"Sukhvir","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6596-6680","authenticated-orcid":false,"given":"Jithmi","family":"Weliwitage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Hellmich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7425-4455","authenticated-orcid":false,"given":"Michael","family":"Hallek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"Schepers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5631-4143","authenticated-orcid":false,"given":"Johann","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6539-226X","authenticated-orcid":false,"given":"Christof","family":"Scheid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2744-5491","authenticated-orcid":false,"given":"Roland","family":"Schroers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg-Nikolaus","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4761-3395","authenticated-orcid":false,"given":"Raymond","family":"Voltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8201-2344","authenticated-orcid":false,"given":"Anne","family":"Pralong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"6981_CR1","doi-asserted-by":"publisher","unstructured":"Wenzel F, Pralong A, Holtick U, Scheid C, Herling M, Simon ST (2021) Burden and Needs of Patients with Severe GvHD from the Supportive and Palliative Care Perspective-A Literature Review. Cancers (Basel) 13. https:\/\/doi.org\/10.3390\/CANCERS13112697","DOI":"10.3390\/CANCERS13112697"},{"key":"6981_CR2","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1038\/s41409-022-01691-w","volume":"57","author":"JA Snowden","year":"2022","unstructured":"Snowden JA, S\u00e1nchez-Ortega I, Corbacioglu S, Basak GW, Chabannon C, de la Camara R et al (2022) Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022. Bone Marrow Transpl 57:1217\u20131239. https:\/\/doi.org\/10.1038\/s41409-022-01691-w","journal-title":"Bone Marrow Transpl"},{"key":"6981_CR3","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1182\/ASHEDUCATION-2010.1.248","volume":"2010","author":"M Bevans","year":"2010","unstructured":"Bevans M (2010) Health-related quality of life following allogeneic hematopoietic stem cell transplantation. Hematology \/ the Education Program of the American Society of Hematology American Society of Hematology. Educ Program 2010:248\u2013254. https:\/\/doi.org\/10.1182\/ASHEDUCATION-2010.1.248","journal-title":"Educ Program"},{"key":"6981_CR4","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/S1470-2045(09)70352-3","volume":"11","author":"B Friedrichs","year":"2010","unstructured":"Friedrichs B, Tichelli A, Bacigalupo A, Russell NH, Ruutu T, Shapira MY et al (2010) Long-term outcome and late effects in patients transplanted with mobilised blood or bone marrow: A randomised trial. Lancet Oncol 11:331\u2013338. https:\/\/doi.org\/10.1016\/S1470-2045(09)70352-3","journal-title":"Lancet Oncol"},{"key":"6981_CR5","doi-asserted-by":"publisher","first-page":"e777","DOI":"10.1016\/S2352-3026(23)00114-X","volume":"10","author":"C Sp\u00e4th","year":"2023","unstructured":"Sp\u00e4th C, Neumann T, Schmidt CA, Heidel FH, Kr\u00fcger WH (2023) Patients receiving allogeneic haematopoietic stem-cell transplantation and clinical outcomes after early access to palliative care. Lancet Haematol 10:e777\u2013e784. https:\/\/doi.org\/10.1016\/S2352-3026(23)00114-X","journal-title":"Lancet Haematol"},{"key":"6981_CR6","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1038\/BMT.2015.113","volume":"50","author":"A El-Jawahri","year":"2015","unstructured":"El-Jawahri A, Traeger L, Kuzmuk K, Eusebio J, Vandusen H, Keenan T et al (2015) Prognostic understanding, quality of life and mood in patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transpl 50:1119\u20131124. https:\/\/doi.org\/10.1038\/BMT.2015.113","journal-title":"Bone Marrow Transpl"},{"key":"6981_CR7","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1200\/JCO.18.02386","volume":"38","author":"A El-Jawahri","year":"2020","unstructured":"El-Jawahri A, Nelson AM, Gray TF, Lee SJ, LeBlanc TW (2020) Palliative and End-of-Life Care for Patients With Hematologic Malignancies. J Clin Oncol 38:944. https:\/\/doi.org\/10.1200\/JCO.18.02386","journal-title":"J Clin Oncol"},{"key":"6981_CR8","doi-asserted-by":"publisher","unstructured":"Howell DA, Shellens R, Roman E, Garry AC, Patmore R, Howard MR (2011) Haematological malignancy: Are patients appropriately referred for specialist palliative and hospice care? A systematic review and meta-analysis of published data. Palliat Med 25:630\u2013641. https:\/\/doi.org\/10.1177\/0269216310391692\/ASSET\/IMAGES\/LARGE\/10.1177_0269216310391692-FIG2.JPEG","DOI":"10.1177\/0269216310391692\/ASSET\/IMAGES\/LARGE\/10.1177_0269216310391692-FIG2.JPEG"},{"key":"6981_CR9","doi-asserted-by":"publisher","first-page":"S559","DOI":"10.1016\/j.jtct.2024.04.020","volume":"30","author":"A Barata","year":"2024","unstructured":"Barata A, Tavori G, Wolff D, Herrmann A (2024) Patient and Physician Communication in the Allogeneic Transplantation Setting: Challenges and Potential Solutions. Transpl Cell Ther 30:S559\u2013S569. https:\/\/doi.org\/10.1016\/j.jtct.2024.04.020","journal-title":"Transpl Cell Ther"},{"key":"6981_CR10","doi-asserted-by":"publisher","unstructured":"Reimer A, Ley M, Schepers C, Pralong A, Schoerger B, Voltz R et al (2024) The life threat in hematopoietic allogeneic stem cell transplantation - an interview and focus group study on health care professionals\u2019 perspectives. Ann Hematol 103. https:\/\/doi.org\/10.1007\/S00277-024-05967-7","DOI":"10.1007\/S00277-024-05967-7"},{"key":"6981_CR11","doi-asserted-by":"publisher","unstructured":"Pralong A, Simon ST, Holtick U, Reimer A, Schoerger B, Kaur S et al (2025) A cross-sectional survey on health care professionals\u2019 approaches, challenges, and support needs when addressing life threat with recipients of an allogeneic hematopoietic stem cell transplantation and with their relatives. Ann Hematol 104. https:\/\/doi.org\/10.1007\/S00277-025-06211-6","DOI":"10.1007\/S00277-025-06211-6"},{"key":"6981_CR12","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1001\/jama.300.14.1665","volume":"300","author":"AA Wright","year":"2008","unstructured":"Wright AA, Zhang B, Alaka Ray M, Mack JW, Elizabeth Trice M, Balboni T et al (2008) Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment. JAMA 300:1665","journal-title":"JAMA"},{"key":"6981_CR13","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1001\/JAMAINTERNMED.2015.6599","volume":"176","author":"OO Odejide","year":"2016","unstructured":"Odejide OO, Cronin AM, Condron N, Earle CC, Wolfe J, Abel GA (2016) Timeliness of End-of-Life Discussions for Blood Cancers: A National Survey of Hematologic Oncologists. JAMA Intern Med 176:263\u2013265. https:\/\/doi.org\/10.1001\/JAMAINTERNMED.2015.6599","journal-title":"JAMA Intern Med"},{"key":"6981_CR14","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1002\/PON.4581","volume":"27","author":"AJ Applebaum","year":"2018","unstructured":"Applebaum AJ, Buda K, Kryza-Lacombe M, Buthorn JJ, Walker R, Shaffer KM et al (2018) Prognostic awareness and communication preferences among caregivers of patients with malignant glioma. Psychooncology 27:817\u2013823. https:\/\/doi.org\/10.1002\/PON.4581","journal-title":"Psychooncology"},{"key":"6981_CR15","doi-asserted-by":"publisher","unstructured":"Zaleta AK, Miller MF, Johnson J, Mcmanus S, Karten C, Mauro MJ et al (2017) Symptom Burden, Palliative Care Needs, and Patient-Provider Communication Among Chronic Myeloid Leukemia Survivors. https:\/\/doi.org\/10.1182\/blood.V130.Suppl_1.4704.4704","DOI":"10.1182\/blood.V130.Suppl_1.4704.4704"},{"key":"6981_CR16","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1093\/annonc\/mdv028","volume":"26","author":"D Hui","year":"2015","unstructured":"Hui D, Bansal S, Park M, Reddy A, Cortes J, Fossella F et al (2015) Differences in attitudes and beliefs toward end-of-life care between hematologic and solid tumor oncology specialists. Ann Oncol 26:1440\u20131446. https:\/\/doi.org\/10.1093\/annonc\/mdv028","journal-title":"Ann Oncol"},{"key":"6981_CR17","doi-asserted-by":"publisher","unstructured":"Pralong A, Herling M, Holtick U, Scheid C, Hellmich M, Hallek M et al (2023) Developing a supportive and palliative care intervention for patients with allogeneic stem cell transplantation: Protocol of a multicentre mixed-methods study (allo-PaS). BMJ Open 13. https:\/\/doi.org\/10.1136\/bmjopen-2022-066948","DOI":"10.1136\/bmjopen-2022-066948"},{"key":"6981_CR18","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1007\/s00277-021-04538-4","volume":"100","author":"ST Simon","year":"2021","unstructured":"Simon ST, Pralong A, Hallek M, Scheid C, Holtick U, Herling M (2021) What is known about palliative care in adult patients with allogeneic stem cell transplantation (allo-SCT)? Ann Hematol 100:1377\u20131389. https:\/\/doi.org\/10.1007\/s00277-021-04538-4","journal-title":"Ann Hematol"},{"key":"6981_CR19","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1017\/S1478951508000199","volume":"6","author":"A Mehnert","year":"2008","unstructured":"Mehnert A, Koch U (2008) Psychometric evaluation of the German version of the Life Attitude Profile\u2013Revised (LAP-R) in prostate cancer patients. Palliat Support Care 6:119\u2013124. https:\/\/doi.org\/10.1017\/S1478951508000199","journal-title":"Palliat Support Care"},{"key":"6981_CR20","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1037\/h0081178","volume":"13","author":"GT Reker","year":"1981","unstructured":"Reker GT, Peacock EJ (1981) The Life Attitude Profile (LAP): A multidimensional instrument for assessing attitudes toward life. Can J Behav Sci 13:264\u2013273. https:\/\/doi.org\/10.1037\/h0081178","journal-title":"Can J Behav Sci"},{"key":"6981_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S40359-019-0336-6\/FIGURES\/2","volume":"7","author":"J Jansen","year":"2019","unstructured":"Jansen J, Schulz-Quach C, Eisenbeck N, Carreno DF, Schmitz A, Fountain R et al (2019) German version of the Death Attitudes Profile- Revised (DAP-GR) - Translation and validation of a multidimensional measurement of attitudes towards death. BMC Psychol 7:1\u201311. https:\/\/doi.org\/10.1186\/S40359-019-0336-6\/FIGURES\/2","journal-title":"BMC Psychol"},{"key":"6981_CR22","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1055\/s-0033-1348218","volume":"92","author":"G Meltendorf","year":"2013","unstructured":"Meltendorf G, Meltendorf C (2013) Patientenaufkl\u00e4rung und Behandlungs-dokumentation - Gesetz zur Verbesserung der Rechte von Patientinnen und Patienten. Laryngorhinootologie 92:482\u2013493. https:\/\/doi.org\/10.1055\/s-0033-1348218","journal-title":"Laryngorhinootologie"},{"key":"6981_CR23","unstructured":"Wong PTP, Reker GT, Gesser G Death Attitude Profile-Revised (DAP-R) n.d"},{"key":"6981_CR24","unstructured":"[The Italian (2026) law 219\/2017: informed consent and advance directives. When the patient-doctor communication time is law, but it is forgotten] - PubMed n.d. https:\/\/pubmed.ncbi.nlm.nih.gov\/38808933\/"},{"key":"6981_CR25","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.zefq.2023.05.005","volume":"180","author":"K G\u00f6tze","year":"2023","unstructured":"G\u00f6tze K, Feddersen B, in der Schmitten J, Marckmann G (2023) Advance Care Planning in Germany. Z Evid Fortbild Qual Gesundhwes 180:127\u2013132. https:\/\/doi.org\/10.1016\/j.zefq.2023.05.005","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"key":"6981_CR26","doi-asserted-by":"publisher","unstructured":"Gray TF, Temel JS, El-Jawahri A (2021) Illness and prognostic understanding in patients with hematologic malignancies. Blood Rev 45. https:\/\/doi.org\/10.1016\/j.blre.2020.100692","DOI":"10.1016\/j.blre.2020.100692"},{"key":"6981_CR27","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/J.LEUKRES.2008.12.008","volume":"33","author":"T Yogaparan","year":"2009","unstructured":"Yogaparan T, Panju A, Minden M, Brandwein J, Mohamedali HZ, Alibhai SMH (2009) Information needs of adult patients 50 or older with newly diagnosed acute myeloid leukemia. Leuk Res 33:1288\u20131290. https:\/\/doi.org\/10.1016\/J.LEUKRES.2008.12.008","journal-title":"Leuk Res"},{"key":"6981_CR28","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1093\/annonc\/mdt557","volume":"25","author":"F Efficace","year":"2014","unstructured":"Efficace F, Gaidano G, Sprangers M, Cottone F, Breccia M, Voso MT et al (2014) Preference for involvement in treatment decisions and request for prognostic information in newly diagnosed patients with higher-risk myelodysplastic syndromes. Ann Oncol 25:447\u2013455. https:\/\/doi.org\/10.1093\/annonc\/mdt557","journal-title":"Ann Oncol"},{"key":"6981_CR29","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/hon.2138","volume":"33","author":"JAJ Rood","year":"2015","unstructured":"Rood JAJ, van Zuuren FJ, Stam F, van der Ploeg T, Eeltink C, Verdonck-de Leeuw IM et al (2015) Perceived need for information among patients with a haematological malignancy: Associations with information satisfaction and treatment decision-making preferences. Hematol Oncol 33:85\u201398 .2138;JOURNAL:JOURNAL:10991069;WGROUP:STRING:PUBLICATION","journal-title":"Hematol Oncol"},{"key":"6981_CR30","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1007\/S00520-002-0424-6\/TABLES\/4","volume":"11","author":"LS Friis","year":"2003","unstructured":"Friis LS, Elverdam B, Schmidt KG (2003) The patient\u2019s perspective: A qualitative study of acute myeloid leukaemia patients\u2019 need for information and their information-seeking behaviour. Support Care Cancer 11:162\u2013170. https:\/\/doi.org\/10.1007\/S00520-002-0424-6\/TABLES\/4","journal-title":"Support Care Cancer"},{"key":"6981_CR31","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.pec.2016.10.008","volume":"100","author":"C Fletcher","year":"2017","unstructured":"Fletcher C, Flight I, Chapman J, Fennell K, Wilson C (2017) The information needs of adult cancer survivors across the cancer continuum: A scoping review. Patient Educ Couns 100:383\u2013410. https:\/\/doi.org\/10.1016\/j.pec.2016.10.008","journal-title":"Patient Educ Couns"},{"key":"6981_CR32","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1634\/theoncologist.5-4-302","volume":"5","author":"WF Baile","year":"2000","unstructured":"Baile WF, Buckman R, Lenzi R, Glober G, Beale EA, Kudelka AP (2000) SPIKES - A six-step protocol for delivering bad news: Application to the patient with cancer. Oncologist 5:302\u2013311. https:\/\/doi.org\/10.1634\/theoncologist.5-4-302","journal-title":"Oncologist"},{"key":"6981_CR33","doi-asserted-by":"publisher","first-page":"610e1","DOI":"10.1016\/J.JTCT.2023.09.023","volume":"30","author":"TF Gray","year":"2024","unstructured":"Gray TF, Do KM, Amonoo HL, Sullivan L, Kelkar AH, Pirl WF et al (2024) Family Caregiver Experiences in the Inpatient and Outpatient Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation Settings: A Qualitative Study. Transpl Cell Ther 30:610e1. https:\/\/doi.org\/10.1016\/J.JTCT.2023.09.023","journal-title":"Transpl Cell Ther"},{"key":"6981_CR34","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1177\/1049909117715215","volume":"35","author":"A Shalev","year":"2018","unstructured":"Shalev A, Phongtankuel V, Kozlov E, Shen MJ, Adelman RD, Reid MC (2018) Awareness and Misperceptions of Hospice and Palliative Care: A Population-Based Survey Study. Am J Hosp Palliat Care 35:431\u2013439. https:\/\/doi.org\/10.1177\/1049909117715215","journal-title":"Am J Hosp Palliat Care"},{"key":"6981_CR35","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1089\/JPM.2023.0630","volume":"27","author":"M Heckel","year":"2024","unstructured":"Heckel M, Peters J, Schweighart S, Habermann M, Ostgathe C (2024) Knowledge and Public Perception of Palliative Care in Germany. J Palliat Med 27:986\u2013992. https:\/\/doi.org\/10.1089\/JPM.2023.0630","journal-title":"J Palliat Med"},{"key":"6981_CR36","doi-asserted-by":"publisher","unstructured":"El-Jawahri A, Webb JA, Breffni H, Zimmermann C (2024) Integrating Palliative Care and Hematologic Malignancies: Bridging the Gaps for Our Patients and Their Caregivers. Am Soc Clin Oncol Educational Book 44. https:\/\/doi.org\/10.1200\/edbk_432196","DOI":"10.1200\/edbk_432196"},{"key":"6981_CR37","doi-asserted-by":"publisher","first-page":"356","DOI":"10.3322\/CAAC.21490","volume":"68","author":"D Hui","year":"2018","unstructured":"Hui D, Hannon BL, Zimmermann C, Bruera E (2018) Improving Patient and Caregiver Outcomes in Oncology: Team-Based, Timely, and Targeted Palliative Care. CA Cancer J Clin 68:356. https:\/\/doi.org\/10.3322\/CAAC.21490","journal-title":"CA Cancer J Clin"},{"key":"6981_CR38","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1634\/theoncologist.2016-0090","volume":"21","author":"D Hui","year":"2016","unstructured":"Hui D, Cerana MA, Park M, Hess K, Bruera E (2016) Impact of Oncologists\u2019 Attitudes Toward End-of-Life Care on Patients\u2019 Access to Palliative Care. Oncologist 21:1149\u20131155. https:\/\/doi.org\/10.1634\/theoncologist.2016-0090","journal-title":"Oncologist"},{"key":"6981_CR39","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1002\/pon.6132","volume":"32","author":"N Harnischfeger","year":"2023","unstructured":"Harnischfeger N, Rath HM, Alt-Epping B, Brand H, Haller K, Letsch A et al (2023) Association between oncologists\u2019 death anxiety and their end-of-life communication with advanced cancer patients. Psychooncology 32:923\u2013932. https:\/\/doi.org\/10.1002\/pon.6132","journal-title":"Psychooncology"}],"container-title":["Annals of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-026-06981-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00277-026-06981-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00277-026-06981-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:25:07Z","timestamp":1781645107000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00277-026-06981-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,2]]},"references-count":39,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["6981"],"URL":"https:\/\/doi.org\/10.1007\/s00277-026-06981-7","relation":{},"ISSN":["1432-0584"],"issn-type":[{"value":"1432-0584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,2]]},"assertion":[{"value":"15 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Study approved by the Ethics Commission of the Faculty of Medicine of the University of Cologne on 23 March 2022 (20-1370_2). Research was carried out in accordance with the relevant guidelines and regulations of this ethical review committee and the the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}],"article-number":"225"}}