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Standard pure tone audiometry alone is inadequate for this context. Comprehensive and consistent hearing tests should be implemented in a monitoring and surveillance program. High-frequency audiometry (10\u201316\u00a0kHz) is a sensitive tool in the detection of ototoxic hearing loss at onset. In addition to threshold audiometry, measures of speech comprehension (both in quiet and in noise) can add useful information in the evaluation of hearing in real-life situations. Not only hearing loss, but also tinnitus and imbalance are common in patients who receive platinum-based chemotherapy, and can cause debilitating effects upon quality of life in this population. Moreover, self-report measures associated with cochlear and vestibular handicaps can provide valuable information regarding the impact of ototoxicity.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>It is vital to build awareness about the variety and impact of the symptoms of ototoxicity. Comprehensive evaluation of hearing status along with self-reported impact of the cochlear and vestibular handicap should be implemented in a monitoring and surveillance program for appropriate investigation and management.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00280-019-04012-z","type":"journal-article","created":{"date-parts":[[2019,12,21]],"date-time":"2019-12-21T08:03:22Z","timestamp":1576915402000},"page":"245-250","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy"],"prefix":"10.1007","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0767-0723","authenticated-orcid":false,"given":"David M.","family":"Baguley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3002-0497","authenticated-orcid":false,"given":"Pattarawadee","family":"Prayuenyong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,21]]},"reference":[{"key":"4012_CR1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a033548","author":"CJ Kros","year":"2018","unstructured":"Kros CJ, Steyger PS (2018) Aminoglycoside- and cisplatin-induced ototoxicity: mechanisms and otoprotective strategies. 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