{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:38:09Z","timestamp":1791221889031,"version":"4.1.0"},"reference-count":109,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T00:00:00Z","timestamp":1741651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T00:00:00Z","timestamp":1741651200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2023YFC2705403"],"award-info":[{"award-number":["2023YFC2705403"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32370914, 92478122, 92357306"],"award-info":[{"award-number":["32370914, 92478122, 92357306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["23ZR1408200"],"award-info":[{"award-number":["23ZR1408200"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Oriental Talent Plan","award":["\/"],"award-info":[{"award-number":["\/"]}]},{"name":"Open Fund for Shanghai Key Laboratory of Embryo Original Diseases","award":["shelab2024ZD02"],"award-info":[{"award-number":["shelab2024ZD02"]}]},{"name":"Chu Ying Project of the International Peace Maternity and Child Health Hospital","award":["CYJH2413"],"award-info":[{"award-number":["CYJH2413"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Semin Immunopathol"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s00281-025-01048-7","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T06:44:37Z","timestamp":1741675477000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["NK cells: shielding senescence homeostasis in the decidua during early pregnancy"],"prefix":"10.1007","volume":"47","author":[{"given":"Zi-Meng","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Wei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-0722","authenticated-orcid":false,"given":"Ming-Qing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,11]]},"reference":[{"key":"1048_CR1","doi-asserted-by":"crossref","unstructured":"Ochoa-Bernal MA, Fazleabas AT (2020) Physiologic events of embryo implantation and decidualization in human and Non-Human Primates. Int J Mol Sci 21","DOI":"10.3390\/ijms21061973"},{"key":"1048_CR2","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1038\/nm.3012","volume":"18","author":"J Cha","year":"2012","unstructured":"Cha J, Sun X, Dey SK (2012) Mechanisms of implantation: strategies for successful pregnancy. Nat Med 18:1754\u20131767","journal-title":"Nat Med"},{"key":"1048_CR3","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1210\/er.2014-1045","volume":"35","author":"B Gellersen","year":"2014","unstructured":"Gellersen B, Brosens JJ (2014) Cyclic decidualization of the human endometrium in reproductive health and failure. Endocr Rev 35:851\u2013905","journal-title":"Endocr Rev"},{"key":"1048_CR4","doi-asserted-by":"crossref","unstructured":"Ng SW, Norwitz GA, Pavlicev M, Tilburgs T, Sim\u00f3n C, Norwitz ER (2020) Endometrial decidualization: the primary driver of pregnancy health. Int J Mol Sci 21","DOI":"10.3390\/ijms21114092"},{"key":"1048_CR5","doi-asserted-by":"publisher","first-page":"101586","DOI":"10.1016\/j.tice.2021.101586","volume":"72","author":"C Ticconi","year":"2021","unstructured":"Ticconi C, Di Simone N, Campagnolo L, Fazleabas A (2021) Clinical consequences of defective decidualization. Tissue Cell 72:101586","journal-title":"Tissue Cell"},{"key":"1048_CR6","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.mam.2012.12.011","volume":"34","author":"S Zhang","year":"2013","unstructured":"Zhang S, Lin H, Kong S, Wang S, Wang H, Wang H, Armant DR (2013) Physiological and molecular determinants of embryo implantation. Mol Aspects Med 34:939\u2013980","journal-title":"Mol Aspects Med"},{"key":"1048_CR7","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.placenta.2017.06.005","volume":"60","author":"KP Conrad","year":"2017","unstructured":"Conrad KP, Rabaglino MB, Post Uiterweer ED (2017) Emerging role for dysregulated decidualization in the genesis of preeclampsia. Placenta 60:119\u2013129","journal-title":"Placenta"},{"key":"1048_CR8","doi-asserted-by":"publisher","first-page":"104223","DOI":"10.1016\/j.jri.2024.104223","volume":"163","author":"ST Goudarzi","year":"2024","unstructured":"Goudarzi ST, Vousooghi N, Verdi J, Mehdizadeh A, Aslanian-Kalkhoran L, Yousefi M (2024) Autophagy genes and signaling pathways in endometrial decidualization and pregnancy complications. J Reprod Immunol 163:104223","journal-title":"J Reprod Immunol"},{"key":"1048_CR9","doi-asserted-by":"publisher","first-page":"728291","DOI":"10.3389\/fimmu.2021.728291","volume":"12","author":"X Zhang","year":"2021","unstructured":"Zhang X, Wei H (2021) Role of decidual natural killer cells in human pregnancy and related pregnancy complications. Front Immunol 12:728291","journal-title":"Front Immunol"},{"key":"1048_CR10","doi-asserted-by":"publisher","first-page":"663660","DOI":"10.3389\/fimmu.2021.663660","volume":"12","author":"Y Liu","year":"2021","unstructured":"Liu Y, Gao S, Zhao Y, Wang H, Pan Q, Shao Q (2021) Decidual natural killer cells: A good Nanny at the Maternal-Fetal interface during early pregnancy. Front Immunol 12:663660","journal-title":"Front Immunol"},{"key":"1048_CR11","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.3389\/fimmu.2019.02317","volume":"10","author":"F Yang","year":"2019","unstructured":"Yang F, Zheng Q, Jin L (2019) Dynamic function and composition changes of immune cells during normal and pathological pregnancy at the Maternal-Fetal interface. Front Immunol 10:2317","journal-title":"Front Immunol"},{"key":"1048_CR12","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1093\/biolre\/ioac094","volume":"107","author":"X Xu","year":"2022","unstructured":"Xu X, Zhou Y, Fu B, Wei H (2022) Uterine NK cell functions at maternal-fetal interface\u2020. Biol Reprod 107:327\u2013338","journal-title":"Biol Reprod"},{"key":"1048_CR13","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1093\/humupd\/dmac006","volume":"28","author":"E Von Woon","year":"2022","unstructured":"Von Woon E, Greer O, Shah N, Nikolaou D, Johnson M, Male V (2022) Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis. Hum Reprod Update 28:548\u2013582","journal-title":"Hum Reprod Update"},{"key":"1048_CR14","doi-asserted-by":"publisher","first-page":"904744","DOI":"10.3389\/fendo.2022.904744","volume":"13","author":"R Fraser","year":"2022","unstructured":"Fraser R, Zenclussen AC (2022) Killer timing: the Temporal uterine natural killer cell differentiation pathway and implications for female reproductive health. Front Endocrinol (Lausanne) 13:904744","journal-title":"Front Endocrinol (Lausanne)"},{"key":"1048_CR15","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1007\/s00018-019-03374-0","volume":"77","author":"P Deryabin","year":"2020","unstructured":"Deryabin P, Griukova A, Nikolsky N, Borodkina A (2020) The link between endometrial stromal cell senescence and decidualization in female fertility: the Art of balance. Cell Mol Life Sci 77:1357\u20131370","journal-title":"Cell Mol Life Sci"},{"key":"1048_CR16","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1093\/humrep\/deac112","volume":"37","author":"PI Deryabin","year":"2022","unstructured":"Deryabin PI, Borodkina AV (2022) Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells. Hum Reprod 37:1505\u20131524","journal-title":"Hum Reprod"},{"key":"1048_CR17","doi-asserted-by":"crossref","unstructured":"Deryabin PI, Ivanova JS, Borodkina AV (2022) Senescent endometrial stromal cells transmit reactive oxygen species to the trophoblast-like cells and impair spreading of blastocyst-like spheroids. Mol Hum Reprod 28","DOI":"10.1093\/molehr\/gaac039"},{"key":"1048_CR18","doi-asserted-by":"crossref","unstructured":"Brighton PJ, Maruyama Y, Fishwick K, Vrljicak P, Tewary S, Fujihara R, Muter J, Lucas ES, Yamada T, Woods L, Lucciola R, Hou Lee Y, Takeda S, Ott S, Hemberger M, Quenby S, Brosens JJ (2017) Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium. Elife 6","DOI":"10.7554\/eLife.31274"},{"key":"1048_CR19","doi-asserted-by":"crossref","unstructured":"Marquez CMD, Ibana JA, Velarde MC (2017) The female reproduction and senescence nexus. Am J Reprod Immunol 77","DOI":"10.1111\/aji.12646"},{"key":"1048_CR20","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1093\/biolre\/ioad071","volume":"109","author":"GS Gong","year":"2023","unstructured":"Gong GS, Muyayalo KP, Zhang YJ, Lin XX, Liao AH (2023) Flip a coin: cell senescence at the maternal-fetal interface\u2020. Biol Reprod 109:244\u2013255","journal-title":"Biol Reprod"},{"key":"1048_CR21","doi-asserted-by":"crossref","unstructured":"Shi JW, Lai ZZ, Zhou WJ, Yang HL, Zhang T, Sun JS, Zhao JY, Li MQ (2024) TNFSF14(+) natural killer cells prevent spontaneous abortion by restricting leucine-mediated decidual stromal cell senescence. Embo J","DOI":"10.1038\/s44318-024-00220-3"},{"key":"1048_CR22","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1080\/15384101.2017.1371888","volume":"16","author":"JM Cha","year":"2017","unstructured":"Cha JM, Aronoff DM (2017) A role for cellular senescence in birth timing. Cell Cycle 16:2023\u20132031","journal-title":"Cell Cycle"},{"key":"1048_CR23","doi-asserted-by":"crossref","unstructured":"Rawlings TM, Makwana K, Taylor DM, Mol\u00e8 MA, Fishwick KJ, Tryfonos M, Odendaal J, Hawkes A, Zernicka-Goetz M, Hartshorne GM, Brosens JJ, Lucas ES (2021) Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. Elife 10","DOI":"10.7554\/eLife.69603"},{"key":"1048_CR24","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1126\/science.adj7050","volume":"384","author":"JP de Magalh\u00e3es","year":"2024","unstructured":"de Magalh\u00e3es JP (2024) Cellular senescence in normal physiology. Science 384:1300\u20131301","journal-title":"Science"},{"key":"1048_CR25","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1124\/pharmrev.122.000622","volume":"75","author":"V Lucas","year":"2023","unstructured":"Lucas V, Cavadas C, Aveleira CA (2023) Cellular senescence: from mechanisms to current biomarkers and senotherapies. Pharmacol Rev 75:675\u2013713","journal-title":"Pharmacol Rev"},{"key":"1048_CR26","doi-asserted-by":"publisher","first-page":"101601","DOI":"10.1016\/j.molmet.2022.101601","volume":"66","author":"AK Palmer","year":"2022","unstructured":"Palmer AK, Tchkonia T, Kirkland JL (2022) Targeting cellular senescence in metabolic disease. Mol Metab 66:101601","journal-title":"Mol Metab"},{"key":"1048_CR27","doi-asserted-by":"crossref","unstructured":"Rhinn M, Ritschka B, Keyes WM (2019) Cellular senescence in development, regeneration and disease. Development 146","DOI":"10.1242\/dev.151837"},{"key":"1048_CR28","first-page":"168","volume":"29","author":"Regulski","year":"2017","unstructured":"Regulski MJ (2017) Cellular senescence: what, why, and how. Wounds 29:168\u2013174","journal-title":"Wounds"},{"key":"1048_CR29","doi-asserted-by":"publisher","first-page":"e13338","DOI":"10.1111\/acel.13338","volume":"20","author":"M Ogrodnik","year":"2021","unstructured":"Ogrodnik M (2021) Cellular aging beyond cellular senescence: markers of senescence prior to cell cycle arrest in vitro and in vivo. Aging Cell 20:e13338","journal-title":"Aging Cell"},{"key":"1048_CR30","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1093\/humupd\/dmw022","volume":"22","author":"R Menon","year":"2016","unstructured":"Menon R, Bonney EA, Condon J, Mesiano S, Taylor RN (2016) Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition. Hum Reprod Update 22:535\u2013560","journal-title":"Hum Reprod Update"},{"key":"1048_CR31","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1093\/biolre\/ioaa113","volume":"103","author":"JC Wijaya","year":"2020","unstructured":"Wijaya JC, Khanabdali R, Georgiou HM, Kalionis B (2020) Ageing in human parturition: impetus of the gestation clock in the decidua\u2020. Biol Reprod 103:695\u2013710","journal-title":"Biol Reprod"},{"key":"1048_CR32","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1093\/humupd\/dmw004","volume":"22","author":"F Schatz","year":"2016","unstructured":"Schatz F, Guzeloglu-Kayisli O, Arlier S, Kayisli UA, Lockwood CJ (2016) The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding. Hum Reprod Update 22:497\u2013515","journal-title":"Hum Reprod Update"},{"key":"1048_CR33","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1172\/JCI40051","volume":"120","author":"Y Hirota","year":"2010","unstructured":"Hirota Y, Daikoku T, Tranguch S, Xie H, Bradshaw HB, Dey SK (2010) Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice. J Clin Invest 120:803\u2013815","journal-title":"J Clin Invest"},{"key":"1048_CR34","doi-asserted-by":"publisher","first-page":"18073","DOI":"10.1073\/pnas.1108180108","volume":"108","author":"Y Hirota","year":"2011","unstructured":"Hirota Y, Cha J, Yoshie M, Daikoku T, Dey SK (2011) Heightened uterine mammalian target of Rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice. Proc Natl Acad Sci U S A 108:18073\u201318078","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1048_CR35","doi-asserted-by":"publisher","first-page":"2441","DOI":"10.1007\/s10815-024-03207-5","volume":"41","author":"R Kendirci-Katirci","year":"2024","unstructured":"Kendirci-Katirci R, Sati L, Celik-Ozenci C (2024) Deciphering the role of Rapamycin in modulating decidual senescence: implications for decidual remodeling and implantation failure. J Assist Reprod Genet 41:2441\u20132456","journal-title":"J Assist Reprod Genet"},{"key":"1048_CR36","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/s42003-020-0763-1","volume":"3","author":"ES Lucas","year":"2020","unstructured":"Lucas ES, Vrljicak P, Muter J, Diniz-da-Costa MM, Brighton PJ, Kong CS, Lipecki J, Fishwick KJ, Odendaal J, Ewington LJ, Quenby S, Ott S, Brosens JJ (2020) Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window. Commun Biol 3:37","journal-title":"Commun Biol"},{"key":"1048_CR37","doi-asserted-by":"publisher","first-page":"102597","DOI":"10.1016\/j.ebiom.2019.102597","volume":"51","author":"S Tewary","year":"2020","unstructured":"Tewary S, Lucas ES, Fujihara R, Kimani PK, Polanco A, Brighton PJ, Muter J, Fishwick KJ, Da Costa M, Ewington LJ, Lacey L, Takeda S, Brosens JJ, Quenby S (2020) Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells: A randomised, double-blind placebo-controlled feasibility trial. EBioMedicine 51:102597","journal-title":"EBioMedicine"},{"key":"1048_CR38","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.fertnstert.2022.12.016","volume":"119","author":"R Hou","year":"2023","unstructured":"Hou R, Huang R, Zhou Y, Lin D, Xu J, Yang L, Wei X, Xie Z, Zhou Q (2023) Single-cell profiling of the microenvironment in decidual tissue from women with missed abortions. Fertil Steril 119:492\u2013503","journal-title":"Fertil Steril"},{"key":"1048_CR39","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1093\/molehr\/gah081","volume":"10","author":"J Nordengren","year":"2004","unstructured":"Nordengren J, Pilka R, Noskova V, Ehinger A, Domanski H, Andersson C, H\u00f8yer-Hansen G, Hansson SR, Cassl\u00e9n B (2004) Differential localization and expression of urokinase plasminogen activator (uPA), its receptor (uPAR), and its inhibitor (PAI-1) mRNA and protein in endometrial tissue during the menstrual cycle. Mol Hum Reprod 10:655\u2013663","journal-title":"Mol Hum Reprod"},{"key":"1048_CR40","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1161\/ATVBAHA.117.309451","volume":"37","author":"DE Vaughan","year":"2017","unstructured":"Vaughan DE, Rai R, Khan SS, Eren M, Ghosh AK (2017) Plasminogen activator Inhibitor-1 is a marker and a mediator of senescence. Arterioscler Thromb Vasc Biol 37:1446\u20131452","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1048_CR41","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.1177\/15353702211026566","volume":"246","author":"H Wang","year":"2021","unstructured":"Wang H, Shi H (2021) Megestrol acetate drives endometrial carcinoma cell senescence via interacting with progesterone receptor B\/FOXO1 axis. Exp Biol Med (Maywood) 246:2307\u20132316","journal-title":"Exp Biol Med (Maywood)"},{"key":"1048_CR42","doi-asserted-by":"crossref","unstructured":"Tsuru A, Yoshie M, Kojima J, Yonekawa R, Azumi M, Kusama K, Nishi H, Tamura K (2022) PGRMC1 Regulates Cellular Senescence via Modulating FOXO1 Expression in Decidualizing Endometrial Stromal Cells. Biomolecules 12","DOI":"10.3390\/biom12081046"},{"key":"1048_CR43","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1093\/biolre\/ioab183","volume":"106","author":"DJ Stadtmauer","year":"2022","unstructured":"Stadtmauer DJ, Wagner GP (2022) Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal\u2020. Biol Reprod 106:155\u2013172","journal-title":"Biol Reprod"},{"key":"1048_CR44","doi-asserted-by":"publisher","first-page":"111070","DOI":"10.1016\/j.ecoenv.2020.111070","volume":"204","author":"B Chen","year":"2020","unstructured":"Chen B, Chai Q, Xu S, Li Q, Wu T, Chen S, Wu L (2020) Silver nanoparticle-activated COX2\/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo. Ecotoxicol Environ Saf 204:111070","journal-title":"Ecotoxicol Environ Saf"},{"key":"1048_CR45","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1016\/j.bbalip.2013.04.005","volume":"1831","author":"S Martien","year":"2013","unstructured":"Martien S, Pluquet O, Vercamer C, Malaquin N, Martin N, Gosselin K, Pourtier A, Abbadie C (2013) Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts. Biochim Biophys Acta 1831:1217\u20131227","journal-title":"Biochim Biophys Acta"},{"key":"1048_CR46","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.mad.2017.08.003","volume":"170","author":"J Cormenier","year":"2018","unstructured":"Cormenier J, Martin N, Desl\u00e9 J, Salazar-Cardozo C, Pourtier A, Abbadie C, Pluquet O (2018) The ATF6\u03b1 arm of the unfolded protein response mediates replicative senescence in human fibroblasts through a COX2\/prostaglandin E(2) intracrine pathway. Mech Ageing Dev 170:82\u201391","journal-title":"Mech Ageing Dev"},{"key":"1048_CR47","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1530\/JME-14-0162","volume":"54","author":"K Kusama","year":"2015","unstructured":"Kusama K, Yoshie M, Tamura K, Imakawa K, Tachikawa E (2015) EPAC2-mediated calreticulin regulates LIF and COX2 expression in human endometrial glandular cells. J Mol Endocrinol 54:17\u201324","journal-title":"J Mol Endocrinol"},{"key":"1048_CR48","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1210\/en.2013-1478","volume":"155","author":"K Kusama","year":"2014","unstructured":"Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, Tachikawa E (2014) The role of exchange protein directly activated by Cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology 155:240\u2013248","journal-title":"Endocrinology"},{"key":"1048_CR49","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/978-1-62703-556-9_11","volume":"1048","author":"Z Wang","year":"2013","unstructured":"Wang Z, Wei D, Xiao H (2013) Methods of cellular senescence induction using oxidative stress. Methods Mol Biol 1048:135\u2013144","journal-title":"Methods Mol Biol"},{"key":"1048_CR50","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.redox.2016.11.005","volume":"11","author":"A Chandrasekaran","year":"2017","unstructured":"Chandrasekaran A, Idelchik M, Melendez JA (2017) Redox control of senescence and age-related disease. Redox Biol 11:91\u2013102","journal-title":"Redox Biol"},{"key":"1048_CR51","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.freeradbiomed.2016.03.008","volume":"95","author":"T Nacarelli","year":"2016","unstructured":"Nacarelli T, Azar A, Sell C (2016) Mitochondrial stress induces cellular senescence in an mTORC1-dependent manner. Free Radic Biol Med 95:133\u2013154","journal-title":"Free Radic Biol Med"},{"key":"1048_CR52","doi-asserted-by":"crossref","unstructured":"Papaconstantinou J (2019) The role of signaling pathways of inflammation and oxidative stress in development of senescence and aging phenotypes in cardiovascular disease. Cells 8","DOI":"10.3390\/cells8111383"},{"key":"1048_CR53","doi-asserted-by":"publisher","first-page":"3429","DOI":"10.1080\/01443615.2022.2144171","volume":"42","author":"W Gao","year":"2022","unstructured":"Gao W, Feng F, Ma X, Zhang R, Li L, Yue F, Lv M, Liu L (2022) Progress of oxidative stress in endometrium decidualization. J Obstet Gynaecol 42:3429\u20133434","journal-title":"J Obstet Gynaecol"},{"key":"1048_CR54","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1186\/s12915-022-01483-0","volume":"20","author":"JW Shi","year":"2022","unstructured":"Shi JW, Lai ZZ, Yang HL, Zhou WJ, Zhao XY, Xie F, Liu SP, Chen WD, Zhang T, Ye JF, Zhou XY, Li MQ (2022) An IGF1-expressing endometrial stromal cell population is associated with human decidualization. BMC Biol 20:276","journal-title":"BMC Biol"},{"key":"1048_CR55","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.placenta.2018.05.008","volume":"67","author":"J Jin","year":"2018","unstructured":"Jin J, Richardson L, Sheller-Miller S, Zhong N, Menon R (2018) Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells. Placenta 67:15\u201323","journal-title":"Placenta"},{"key":"1048_CR56","doi-asserted-by":"crossref","unstructured":"Ivanov D, Drobintseva A, Rodichkina V, Mironova E, Zubareva T, Krylova Y, Morozkina S, Marasco MGP, Mazzoccoli G, Nasyrov R, Kvetnoy I (2024) Inflammaging: Expansion of Molecular Phenotype and Role in Age-Associated Female Infertility. Biomedicines 12","DOI":"10.3390\/biomedicines12091987"},{"key":"1048_CR57","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1002\/art.42068","volume":"74","author":"M Tong","year":"2022","unstructured":"Tong M, Kayani T, Jones DM, Salmon JE, Whirledge S, Chamley LW, Abrahams VM (2022) Antiphospholipid antibodies increase endometrial stromal cell decidualization, senescence, and inflammation via Toll-like receptor 4, reactive oxygen species, and p38 MAPK signaling. Arthritis Rheumatol 74:1001\u20131012","journal-title":"Arthritis Rheumatol"},{"key":"1048_CR58","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1038\/s42255-021-00483-8","volume":"3","author":"CD Wiley","year":"2021","unstructured":"Wiley CD, Campisi J (2021) The metabolic roots of senescence: mechanisms and opportunities for intervention. Nat Metabolism 3:1290\u20131301","journal-title":"Nat Metabolism"},{"key":"1048_CR59","doi-asserted-by":"publisher","first-page":"116962","DOI":"10.1016\/j.biopha.2024.116962","volume":"177","author":"Z Wang","year":"2024","unstructured":"Wang Z, Gao J, Xu C (2024) Targeting metabolism to influence cellular senescence a promising anti-cancer therapeutic strategy. Biomed Pharmacother 177:116962","journal-title":"Biomed Pharmacother"},{"key":"1048_CR60","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1002\/cac2.12591","volume":"44","author":"F Zhang","year":"2024","unstructured":"Zhang F, Guo J, Yu S, Zheng Y, Duan M, Zhao L, Wang Y, Yang Z, Jiang X (2024) Cellular senescence and metabolic reprogramming: unraveling the intricate crosstalk in the immunosuppressive tumor microenvironment. Cancer Commun (Lond) 44:929\u2013966","journal-title":"Cancer Commun (Lond)"},{"key":"1048_CR61","doi-asserted-by":"publisher","first-page":"102294","DOI":"10.1016\/j.arr.2024.102294","volume":"97","author":"Q Zeng","year":"2024","unstructured":"Zeng Q, Gong Y, Zhu N, Shi Y, Zhang C, Qin L (2024) Lipids and lipid metabolism in cellular senescence: emerging targets for age-related diseases. Ageing Res Rev 97:102294","journal-title":"Ageing Res Rev"},{"key":"1048_CR62","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1038\/s41586-019-0920-1","volume":"566","author":"W-S Choi","year":"2019","unstructured":"Choi W-S, Lee G, Song W-H, Koh J-T, Yang J, Kwak J-S, Kim H-E, Kim SK, Son Y-O, Nam H, Jin I, Park Z-Y, Kim J, Park IY, Hong J-I, Kim HA, Chun C-H, Ryu J-H, Chun J-S (2019) The CH25H\u2013CYP7B1\u2013ROR\u03b1 axis of cholesterol metabolism regulates osteoarthritis. Nature 566:254\u2013258","journal-title":"Nature"},{"key":"1048_CR63","doi-asserted-by":"publisher","first-page":"9240","DOI":"10.18632\/aging.103200","volume":"12","author":"H Wang","year":"2020","unstructured":"Wang H, Fu H, Zhu R, Wu X, Ji X, Li X, Jiang H, Lin Z, Tang X, Sun S, Chen J, Wang X, Li Q, Ji Y, Chen H (2020) BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. Aging 12:9240\u20139259","journal-title":"Aging"},{"key":"1048_CR64","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1038\/s42255-023-00747-5","volume":"5","author":"K Roh","year":"2023","unstructured":"Roh K, Noh J, Kim Y, Jang Y, Kim J, Choi H, Lee Y, Ji M, Kang D, Kim M-S, Paik M-J, Chung J, Kim J-H, Kang C (2023) Lysosomal control of senescence and inflammation through cholesterol partitioning. Nat Metabolism 5:398\u2013413","journal-title":"Nat Metabolism"},{"key":"1048_CR65","doi-asserted-by":"publisher","first-page":"33023","DOI":"10.1038\/srep33023","volume":"6","author":"I Lanekoff","year":"2016","unstructured":"Lanekoff I, Cha J, Kyle JE, Dey SK, Laskin J, Burnum-Johnson KE (2016) Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site. Sci Rep 6:33023","journal-title":"Sci Rep"},{"key":"1048_CR66","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.2174\/1389557516666160620095103","volume":"18","author":"X Bai","year":"2018","unstructured":"Bai X, Yao L, Ma X, Xu X (2018) Small molecules as SIRT modulators. Mini Rev Med Chem 18:1151\u20131157","journal-title":"Mini Rev Med Chem"},{"key":"1048_CR67","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1097\/NEN.0b013e3181922348","volume":"68","author":"C Julien","year":"2009","unstructured":"Julien C, Tremblay C, Emond V, Lebbadi M, Salem N Jr., Bennett DA, Calon F (2009) Sirtuin 1 reduction parallels the accumulation of Tau in alzheimer disease. J Neuropathol Exp Neurol 68:48\u201358","journal-title":"J Neuropathol Exp Neurol"},{"key":"1048_CR68","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s11926-016-0591-y","volume":"18","author":"M Dvir-Ginzberg","year":"2016","unstructured":"Dvir-Ginzberg M, Mobasheri A, Kumar A (2016) The role of sirtuins in cartilage homeostasis and osteoarthritis. Curr Rheumatol Rep 18:43","journal-title":"Curr Rheumatol Rep"},{"key":"1048_CR69","doi-asserted-by":"crossref","unstructured":"Cummings MJ, Yu H, Paudel S, Hu G, Li X, Hemberger M, Wang X (2022) Uterine-specific SIRT1 deficiency confers premature uterine aging and impairs invasion and spacing of blastocyst, and stromal cell decidualization, in mice. Mol Hum Reprod 28","DOI":"10.1093\/molehr\/gaac016"},{"key":"1048_CR70","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1002\/rmb2.12303","volume":"19","author":"A Ochiai","year":"2020","unstructured":"Ochiai A, Kuroda K (2020) Preconception Resveratrol intake against infertility: friend or foe? Reprod Med Biol 19:107\u2013113","journal-title":"Reprod Med Biol"},{"key":"1048_CR71","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1111\/fcp.12915","volume":"37","author":"D Shang","year":"2023","unstructured":"Shang D, Liu H, Tu Z (2023) Pro-inflammatory cytokines mediating senescence of vascular endothelial cells in atherosclerosis. Fundam Clin Pharmacol 37:928\u2013936","journal-title":"Fundam Clin Pharmacol"},{"key":"1048_CR72","doi-asserted-by":"publisher","first-page":"e13145","DOI":"10.1111\/acel.13145","volume":"19","author":"D Shang","year":"2020","unstructured":"Shang D, Sun D, Shi C, Xu J, Shen M, Hu X, Liu H, Tu Z (2020) Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. Aging Cell 19:e13145","journal-title":"Aging Cell"},{"key":"1048_CR73","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1186\/s12964-024-01740-5","volume":"22","author":"K Kawamura","year":"2024","unstructured":"Kawamura K, Matsumura Y, Kawamura T, Araki H, Hamada N, Kuramoto K, Yagi H, Onoyama I, Asanoma K, Kato K (2024) Endometrial senescence is mediated by Interleukin 17 receptor B signaling. Cell Commun Signal 22:363","journal-title":"Cell Commun Signal"},{"key":"1048_CR74","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1038\/s41420-024-02048-6","volume":"10","author":"RN Taylor","year":"2024","unstructured":"Taylor RN, Berga SL, Zou E, Washington J, Song S, Marzullo BJ, Bagchi IC, Bagchi MK, Yu J (2024) Interleukin-1\u03b2 induces and accelerates human endometrial stromal cell senescence and impairs decidualization via the c-Jun N-terminal kinase pathway. Cell Death Discov 10:288","journal-title":"Cell Death Discov"},{"key":"1048_CR75","doi-asserted-by":"publisher","first-page":"3108","DOI":"10.1182\/blood-2007-08-105965","volume":"111","author":"C Carlino","year":"2008","unstructured":"Carlino C, Stabile H, Morrone S, Bulla R, Soriani A, Agostinis C, Bossi F, Mocci C, Sarazani F, Tedesco F, Santoni A, Gismondi A (2008) Recruitment of Circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy. Blood 111:3108\u20133115","journal-title":"Blood"},{"key":"1048_CR76","doi-asserted-by":"crossref","unstructured":"Lash GE, Robson SC, Bulmer JN (2010) Review: Functional role of uterine natural killer (uNK) cells in human early pregnancy decidua. Placenta 31 Suppl: S87-92","DOI":"10.1016\/j.placenta.2009.12.022"},{"key":"1048_CR77","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1093\/intimm\/dxn105","volume":"20","author":"P Vacca","year":"2008","unstructured":"Vacca P, Cantoni C, Prato C, Fulcheri E, Moretta A, Moretta L, Mingari MC (2008) Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells. Int Immunol 20:1395\u20131405","journal-title":"Int Immunol"},{"key":"1048_CR78","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1093\/humupd\/dmaa062","volume":"27","author":"I D\u00edaz-Hern\u00e1ndez","year":"2021","unstructured":"D\u00edaz-Hern\u00e1ndez I, Alecsandru D, Garc\u00eda-Velasco JA, Dom\u00ednguez F (2021) Uterine natural killer cells: from foe to friend in reproduction. Hum Reprod Update 27:720\u2013746","journal-title":"Hum Reprod Update"},{"key":"1048_CR79","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1038\/onc.2012.206","volume":"32","author":"A Sagiv","year":"2013","unstructured":"Sagiv A, Biran A, Yon M, Simon J, Lowe SW, Krizhanovsky V (2013) Granule exocytosis mediates immune surveillance of senescent cells. Oncogene 32:1971\u20131977","journal-title":"Oncogene"},{"key":"1048_CR80","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1002\/JLB.MR0718-299R","volume":"105","author":"F Antonangeli","year":"2019","unstructured":"Antonangeli F, Zingoni A, Soriani A, Santoni A (2019) Senescent cells: living or dying is a matter of NK cells. J Leukoc Biol 105:1275\u20131283","journal-title":"J Leukoc Biol"},{"key":"1048_CR81","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1186\/s13075-022-02859-x","volume":"24","author":"Y Liu","year":"2022","unstructured":"Liu Y, Zhang Z, Li T, Xu H, Zhang H (2022) Senescence in osteoarthritis: from mechanism to potential treatment. Arthritis Res Ther 24:174","journal-title":"Arthritis Res Ther"},{"key":"1048_CR82","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.jri.2009.06.123","volume":"82","author":"H El Costa","year":"2009","unstructured":"El Costa H, Tabiasco J, Berrebi A, Parant O, Aguerre-Girr M, Piccinni MP, Le Bouteiller P (2009) Effector functions of human decidual NK cells in healthy early pregnancy are dependent on the specific engagement of natural cytotoxicity receptors. J Reprod Immunol 82:142\u2013147","journal-title":"J Reprod Immunol"},{"key":"1048_CR83","doi-asserted-by":"publisher","first-page":"1353556","DOI":"10.3389\/fimmu.2024.1353556","volume":"15","author":"D Feyaerts","year":"2024","unstructured":"Feyaerts D, Benner M, Comitini G, Shadmanfar W, van der Heijden OWH, Joosten I, van der Molen RG (2024) NK cell receptor profiling of endometrial and decidual NK cells reveals pregnancy-induced adaptations. Front Immunol 15:1353556","journal-title":"Front Immunol"},{"key":"1048_CR84","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/s41593-020-00745-w","volume":"24","author":"WN Jin","year":"2021","unstructured":"Jin WN, Shi K, He W, Sun JH, Van Kaer L, Shi FD, Liu Q (2021) Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition. Nat Neurosci 24:61\u201373","journal-title":"Nat Neurosci"},{"key":"1048_CR85","doi-asserted-by":"publisher","first-page":"6527","DOI":"10.7150\/thno.74053","volume":"12","author":"ZZ Lai","year":"2022","unstructured":"Lai ZZ, Wang Y, Zhou WJ, Liang Z, Shi JW, Yang HL, Xie F, Chen WD, Zhu R, Zhang C, Mei J, Zhao JY, Ye JF, Zhang T, Li MQ (2022) Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure. Theranostics 12:6527\u20136547","journal-title":"Theranostics"},{"key":"1048_CR86","doi-asserted-by":"publisher","first-page":"3159","DOI":"10.1007\/s43032-024-01653-1","volume":"31","author":"KT Rytk\u00f6nen","year":"2024","unstructured":"Rytk\u00f6nen KT, Adossa N, Z\u00fa\u00f1iga Norman S, L\u00f6nnberg T, Poutanen M, Elo LL (2024) Gene regulatory network analysis of decidual stromal cells and natural killer cells. Reprod Sci 31:3159\u20133174","journal-title":"Reprod Sci"},{"key":"1048_CR87","doi-asserted-by":"publisher","first-page":"e21336","DOI":"10.1096\/fj.202002217R","volume":"35","author":"CS Kong","year":"2021","unstructured":"Kong CS, Ordo\u00f1ez AA, Turner S, Tremaine T, Muter J, Lucas ES, Salisbury E, Vassena R, Tiscornia G, Fouladi-Nashta AA, Hartshorne G, Brosens JJ, Brighton PJ (2021) Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation. Faseb J 35:e21336","journal-title":"Faseb J"},{"key":"1048_CR88","doi-asserted-by":"publisher","first-page":"103776","DOI":"10.1016\/j.jri.2022.103776","volume":"155","author":"S Zeng","year":"2023","unstructured":"Zeng S, Liang Y, Lai S, Bi S, Huang L, Li Y, Deng W, Xu P, Liu M, Xiong Z, Chen J, Tu Z, Chen D, Du L (2023) TNF\u03b1\/TNFR1 signal induces excessive senescence of decidua stromal cells in recurrent pregnancy loss. J Reprod Immunol 155:103776","journal-title":"J Reprod Immunol"},{"key":"1048_CR89","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.gpb.2020.11.002","volume":"19","author":"F Wang","year":"2021","unstructured":"Wang F, Jia W, Fan M, Shao X, Li Z, Liu Y, Ma Y, Li YX, Li R, Tu Q, Wang YL (2021) Single-cell immune landscape of human recurrent miscarriage. Genomics Proteom Bioinf 19:208\u2013222","journal-title":"Genomics Proteom Bioinf"},{"key":"1048_CR90","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s12522-015-0207-7","volume":"14","author":"A Fukui","year":"2015","unstructured":"Fukui A, Kamoi M, Funamizu A, Fuchinoue K, Chiba H, Yokota M, Fukuhara R, Mizunuma H (2015) NK cell abnormality and its treatment in women with reproductive failures such as recurrent pregnancy loss, implantation failures, preeclampsia, and pelvic endometriosis. Reprod Med Biol 14:151\u2013157","journal-title":"Reprod Med Biol"},{"key":"1048_CR91","doi-asserted-by":"publisher","first-page":"e12478","DOI":"10.1002\/rmb2.12478","volume":"21","author":"M Yamamoto","year":"2022","unstructured":"Yamamoto M, Fukui A, Mai C, Saeki S, Takayama R, Wakimoto Y, Yamaya A, Kwak-Kim J, Shibahara H (2022) Evaluation of NKp46 expression and cytokine production of decidual NK cells in women with recurrent pregnancy loss. Reprod Med Biol 21:e12478","journal-title":"Reprod Med Biol"},{"key":"1048_CR92","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1093\/humrep\/deae246","volume":"39","author":"X Tang","year":"2024","unstructured":"Tang X, Zhu Y, Cao Z, Wang X, Cai X, Tang Y, Zhou J, Wu M, Zhen X, Ding L, Yan G, Wang H, Sun H, Jiang R (2024) CDC42 deficiency leads to endometrial stromal cell senescence in recurrent implantation failure. Hum Reprod 39:2768\u20132784","journal-title":"Hum Reprod"},{"key":"1048_CR93","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s12958-024-01265-z","volume":"22","author":"J Delenko","year":"2024","unstructured":"Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, Adelson RP, Safaric Tepes P, Gregersen PK, Metz CN (2024) Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol 22:100","journal-title":"Reprod Biol Endocrinol"},{"key":"1048_CR94","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.bbrc.2021.07.075","volume":"571","author":"K Kusama","year":"2021","unstructured":"Kusama K, Yamauchi N, Yoshida K, Azumi M, Yoshie M, Tamura K (2021) Senolytic treatment modulates decidualization in human endometrial stromal cells. Biochem Biophys Res Commun 571:174\u2013180","journal-title":"Biochem Biophys Res Commun"},{"key":"1048_CR95","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.18632\/aging.102772","volume":"12","author":"MB Cavalcante","year":"2020","unstructured":"Cavalcante MB, Saccon TD, Nunes ADC, Kirkland JL, Tchkonia T, Schneider A, Masternak MM (2020) Dasatinib plus Quercetin prevents uterine age-related dysfunction and fibrosis in mice. Aging 12:2711\u20132722","journal-title":"Aging"},{"key":"1048_CR96","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1093\/humupd\/dmad019","volume":"29","author":"ADS Pathare","year":"2023","unstructured":"Pathare ADS, Loid M, Saare M, Gidl\u00f6f SB, Zamani Esteki M, Acharya G, Peters M, Salumets A (2023) Endometrial receptivity in women of advanced age: an underrated factor in infertility. Hum Reprod Update 29:773\u2013793","journal-title":"Hum Reprod Update"},{"key":"1048_CR97","doi-asserted-by":"crossref","unstructured":"Zhou DD, Luo M, Huang SY, Saimaiti A, Shang A, Gan RY, Li HB (2021) Effects and Mechanisms of Resveratrol on Aging and Age-Related Diseases. Oxid Med Cell Longev 2021: 9932218","DOI":"10.1155\/2021\/9932218"},{"key":"1048_CR98","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1038\/s41419-019-1511-7","volume":"10","author":"A Ochiai","year":"2019","unstructured":"Ochiai A, Kuroda K, Ozaki R, Ikemoto Y, Murakami K, Muter J, Matsumoto A, Itakura A, Brosens JJ, Takeda S (2019) Resveratrol inhibits decidualization by accelerating downregulation of the CRABP2-RAR pathway in differentiating human endometrial stromal cells. Cell Death Dis 10:276","journal-title":"Cell Death Dis"},{"key":"1048_CR99","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1093\/biolre\/ioaa172","volume":"103","author":"K Kuroda","year":"2020","unstructured":"Kuroda K, Ochiai A, Brosens JJ (2020) The actions of Resveratrol in decidualizing endometrium: acceleration or inhibition?\u2020. Biol Reprod 103:1152\u20131156","journal-title":"Biol Reprod"},{"key":"1048_CR100","doi-asserted-by":"publisher","first-page":"792","DOI":"10.3389\/fimmu.2019.00792","volume":"10","author":"Y Yao","year":"2019","unstructured":"Yao Y, Xu XH, Jin L (2019) Macrophage polarization in physiological and pathological pregnancy. Front Immunol 10:792","journal-title":"Front Immunol"},{"key":"1048_CR101","doi-asserted-by":"publisher","first-page":"758281","DOI":"10.3389\/fimmu.2021.758281","volume":"12","author":"J Ding","year":"2021","unstructured":"Ding J, Zhang Y, Cai X, Diao L, Yang C, Yang J (2021) Crosstalk between trophoblast and macrophage at the Maternal-Fetal interface: current status and future perspectives. Front Immunol 12:758281","journal-title":"Front Immunol"},{"key":"1048_CR102","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.7150\/thno.91119","volume":"14","author":"Y Deng","year":"2024","unstructured":"Deng Y, Chen Q, Yang X, Sun Y, Zhang B, Wei W, Deng S, Meng J, Hu Y, Wang Y, Zhang Z, Wen L, Huang F, Wan C, Yang K (2024) Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment. Theranostics 14:1224\u20131240","journal-title":"Theranostics"},{"key":"1048_CR103","doi-asserted-by":"crossref","unstructured":"Behmoaras J, Gil J (2021) Similarities and interplay between senescent cells and macrophages. J Cell Biol 220","DOI":"10.1083\/jcb.202010162"},{"key":"1048_CR104","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.18632\/aging.101268","volume":"9","author":"BM Hall","year":"2017","unstructured":"Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, Rydkina E, Vujcic S, Balan K, Gitlin II, Leonova KI, Consiglio CR, Gollnick SO, Chernova OB, Gudkov AV (2017) p16(Ink4a) and senescence-associated \u03b2-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli. Aging 9:1867\u20131884","journal-title":"Aging"},{"key":"1048_CR105","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1186\/s13046-019-1198-8","volume":"38","author":"M Mazzoni","year":"2019","unstructured":"Mazzoni M, Mauro G, Erreni M, Romeo P, Minna E, Vizioli MG, Belgiovine C, Rizzetti MG, Pagliardini S, Avigni R, Anania MC, Allavena P, Borrello MG, Greco A (2019) Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. J Exp Clin Cancer Res 38:208","journal-title":"J Exp Clin Cancer Res"},{"key":"1048_CR106","unstructured":"Wang L, Yin Z, Shen Y, Feng G, Dai F, Yang D, Deng Z, Yang J, Chen R, Yang L, Chen X, Sun Q, Huang C, Cheng Y, Deng H, Diao L, Li L, Yin T 2024. Targeting decidual CD16(+) immune cells with Exosome-Based glucocorticoid nanoparticles for miscarriage. Adv Sci (Weinh): e2406370"},{"key":"1048_CR107","doi-asserted-by":"publisher","first-page":"107028","DOI":"10.1016\/j.isci.2023.107028","volume":"26","author":"VK Sirohi","year":"2023","unstructured":"Sirohi VK, Medrano TI, Kannan A, Bagchi IC, Cooke PS (2023) Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss. iScience 26:107028","journal-title":"iScience"},{"key":"1048_CR108","doi-asserted-by":"publisher","first-page":"9912","DOI":"10.18632\/aging.102441","volume":"11","author":"A Griukova","year":"2019","unstructured":"Griukova A, Deryabin P, Shatrova A, Burova E, Severino V, Farina A, Nikolsky N, Borodkina A (2019) Molecular basis of senescence transmitting in the population of human endometrial stromal cells. Aging 11:9912\u20139931","journal-title":"Aging"},{"key":"1048_CR109","doi-asserted-by":"crossref","unstructured":"Kelleher AM, Setlem R, Dantzer F, DeMayo FJ, Lydon JP, Kraus WL (2021) Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss. Proc Natl Acad Sci U S A 118","DOI":"10.1073\/pnas.2109252118"}],"container-title":["Seminars in Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00281-025-01048-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00281-025-01048-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00281-025-01048-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:38:55Z","timestamp":1778672335000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00281-025-01048-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,11]]},"references-count":109,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["1048"],"URL":"https:\/\/doi.org\/10.1007\/s00281-025-01048-7","relation":{},"ISSN":["1863-2297","1863-2300"],"issn-type":[{"value":"1863-2297","type":"print"},{"value":"1863-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,11]]},"assertion":[{"value":"8 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors contributed to the study conception and design. The first draft of the manuscript was written by ZM Z. JW S, L W and MQ L reviewed and edited the manuscript critically for important intellectual content and provide comments and feedback for the scientific contents of the manuscript. All authors read and approved the final manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contribution"}},{"value":"The authors have declared that no competing interest exists.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"22"}}