{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:16:35Z","timestamp":1792782995514,"version":"4.5.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["H2015201076"],"award-info":[{"award-number":["H2015201076"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81000760"],"award-info":[{"award-number":["81000760"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Construction Special Project of Hebei University","award":["2014A2003"],"award-info":[{"award-number":["2014A2003"]}],"id":[{"id":"https:\/\/ror.org\/01p884a79","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s00284-018-1471-7","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T03:25:02Z","timestamp":1523330702000},"page":"952-959","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Altered Profiles of Gut Microbiota in Klebsiella pneumoniae-Induced Pyogenic Liver Abscess"],"prefix":"10.1007","volume":"75","author":[{"given":"Nan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zong-Xin","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong-Tong","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Shuang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Liang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Ping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-cong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,4,10]]},"reference":[{"key":"1471_CR1","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1128\/AEM.63.7.2747-2753.1997","volume":"63","author":"MF Bernet-Camard","year":"1997","unstructured":"Bernet-Camard MF, Li\u00e9vin V, Brassart D et al (1997) The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo. Appl Environ Microbiol 63:2747\u20132753","journal-title":"Appl Environ Microbiol"},{"key":"1471_CR2","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1053\/j.gastro.2014.01.059","volume":"146","author":"RA Britton","year":"2014","unstructured":"Britton RA, Young VB (2014) Role of the intestinal microbiota in resistance to colonization by Clostridium difficile. Gastroenterology 146:1547\u20131553","journal-title":"Gastroenterology"},{"key":"1471_CR3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.micpath.2014.08.006","volume":"75","author":"N Chen","year":"2014","unstructured":"Chen N, Wang LL, Xue J et al (2014) Different metabolic profiles of K1 serotype and non-serotype K1 and K2 Klebsiella pneumoniae isolates in oral infection mice model. Microb Pathog 75:41\u201348","journal-title":"Microb Pathog"},{"key":"1471_CR4","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.jinf.2006.11.008","volume":"54","author":"DR Chung","year":"2007","unstructured":"Chung DR, Lee SS, Lee HR et al (2007) Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. J Infect 54:578\u2013583","journal-title":"J Infect"},{"key":"1471_CR5","doi-asserted-by":"publisher","first-page":"2945","DOI":"10.1099\/ijs.0.65848-0","volume":"58","author":"MJ Claesson","year":"2008","unstructured":"Claesson MJ, Van Sinderen D, O\u2019Toole PW (2008) Lactobacillus phylogenomics-towards a reclassifcation of the genus. Int J Syst Evol Microbiol 58:2945\u20132954","journal-title":"Int J Syst Evol Microbiol"},{"key":"1471_CR6","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1093\/biomet\/40.3-4.237","volume":"40","author":"IJ Good","year":"1953","unstructured":"Good IJ (1953) The population frequencies of species and the estimation of population parameters. Biometrika 40:237\u2013264","journal-title":"Biometrika"},{"key":"1471_CR7","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/S0168-1605(01)00440-8","volume":"67","author":"PK Gopal","year":"2001","unstructured":"Gopal PK, Prasad J, Smart J et al (2001) In vitro adherence properties of Lactobacillus rhamnosus DR20 and Bifdobacteriumlactis DR10 strains and their antagonistic activity against an enterotoxigenic Escherichia coli. Int J Food Microbiol 67:207\u2013216","journal-title":"Int J Food Microbiol"},{"key":"1471_CR8","first-page":"2108","volume":"7","author":"M He","year":"2016","unstructured":"He M, Fang S, Huang X et al (2016) Evaluating the contribution of gut microbiota to the variation of porcine fatness with the cecum and fecal samples. Front Microbiol 7:2108","journal-title":"Front Microbiol"},{"key":"1471_CR9","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1128\/AEM.63.2.513-518.1997","volume":"63","author":"S Hudault","year":"1997","unstructured":"Hudault S, Lievin V, Bernet-Camard MF et al (1997) Antagonistic activity exerted in vitro and in vivo by Lactobacillus casei (strain GG) against Salmonella typhimurium C5 infection. Appl Environ Microbiol 63:513\u2013518","journal-title":"Appl Environ Microbiol"},{"key":"1471_CR10","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1016\/j.ajem.2013.02.045","volume":"31","author":"SH Kuo","year":"2013","unstructured":"Kuo SH, Lee YT, Li CR et al (2013) Mortality in emergency department sepsis score as a prognostic indicator in patients with pyogenic liver abscess. Am J Emerg Med 31:916\u2013921","journal-title":"Am J Emerg Med"},{"key":"1471_CR11","doi-asserted-by":"publisher","first-page":"e79961","DOI":"10.1371\/journal.pone.0079961","volume":"8","author":"YC Lin","year":"2013","unstructured":"Lin YC, Lu MC, Lin C et al (2013) Activation of IFN-\u03b3\/STAT\/IRF-1 in hepatic responses to Klebsiella pneumoniae Infection. PLoS ONE 8:e79961","journal-title":"PLoS ONE"},{"key":"1471_CR12","doi-asserted-by":"publisher","first-page":"7485","DOI":"10.1038\/srep07485","volume":"4","author":"Z Ling","year":"2014","unstructured":"Ling Z, Liu X, Jia X et al (2014) Impacts of infection with different toxigenic Clostridium difficile strains on faecal microbiota in children. Sci Rep 4:7485","journal-title":"Sci Rep"},{"key":"1471_CR13","doi-asserted-by":"publisher","first-page":"17098","DOI":"10.1038\/srep17098","volume":"5","author":"Z Ling","year":"2015","unstructured":"Ling Z, Liu X et al (2015) Decreased diversity of the oral microbiota of patients with hepatitis B virus-induced chronic liver disease: a pilot project. Sci Rep 5:17098","journal-title":"Sci Rep"},{"key":"1471_CR14","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1056\/NEJMra1600266","volume":"375","author":"SV Lynch","year":"2016","unstructured":"Lynch SV, Pedersen O (2016) The human intestinal microbiome in health and disease. New Engl J Med 375:2369\u20132379","journal-title":"New Engl J Med"},{"key":"1471_CR15","doi-asserted-by":"publisher","first-page":"441","DOI":"10.4161\/gmic.29599","volume":"5","author":"C Roderburg","year":"2014","unstructured":"Roderburg C, Luedde T (2014) The role of the gut microbiome in the development and progression of liver cirrhosis and hepatocellular carcinoma. Gut Microbes 5:441\u2013445","journal-title":"Gut Microbes"},{"key":"1471_CR16","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s11892-017-0841-z","volume":"17","author":"A Sabatino","year":"2017","unstructured":"Sabatino A, Regolisti G, Cosola C et al (2017) Intestinal microbiota in Type 2 diabetes and chronic kidney disease. Curr Diab Rep 17:16","journal-title":"Curr Diab Rep"},{"key":"1471_CR17","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1086\/342912","volume":"35","author":"MK Salminen","year":"2002","unstructured":"Salminen MK, Tynkkynen S, Rautelin H et al (2002) Lactobacillus bacteremia during a rapid increase in probiotic use of Lactobacillus rhamnosus GG in Finland. Clin Infect Dis 35:1155\u20131160","journal-title":"Clin Infect Dis"},{"key":"1471_CR18","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1080\/00365540500449826","volume":"38","author":"A Sullivan","year":"2006","unstructured":"Sullivan A, Nord CE (2006) Probiotic lactobacilli and bacteraemia in Stockholm. Scand J Infect Dis 38:327\u2013331","journal-title":"Scand J Infect Dis"},{"key":"1471_CR19","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.3748\/wjg.v11.i8.1131","volume":"11","author":"A Swidsinski","year":"2005","unstructured":"Swidsinski A, Loening-Baucke V, Lochs H et al (2005) Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice. World J Gastroenterol 11:1131\u20131140","journal-title":"World J Gastroenterol"},{"key":"1471_CR20","doi-asserted-by":"publisher","first-page":"2657","DOI":"10.1128\/IAI.01523-08","volume":"77","author":"YC Tu","year":"2009","unstructured":"Tu YC, Lu MC, Chiang MK et al (2009) Genetic requirements for Klebsiella pneumoniae-induced liver abscess in an oral infection model. Infect Immun 77:2657\u20132671","journal-title":"Infect Immun"},{"key":"1471_CR21","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1099\/jmm.0.46964-0","volume":"56","author":"JF Turton","year":"2007","unstructured":"Turton JF, Englender H, Gabriel SN et al (2007) Genetically similar isolates of Klebsiella pneumoniae serotype K1 causing liver abscesses in three continents. J Med Microbiol 56:593\u2013597","journal-title":"J Med Microbiol"},{"key":"1471_CR22","doi-asserted-by":"publisher","first-page":"107","DOI":"10.2174\/1874285801105010107","volume":"5","author":"A Vila","year":"2011","unstructured":"Vila A, Cassata A, Pagella H et al (2011) Appearance of Klebsiella pneumoniae liver abscess syndrome in Argentina: case report and review of molecular mechanisms of pathogenesis. Open Microbiol J 5:107\u2013113","journal-title":"Open Microbiol J"},{"key":"1471_CR23","doi-asserted-by":"publisher","first-page":"G112","DOI":"10.1152\/ajpgi.00294.2016","volume":"312","author":"A Zaborin","year":"2017","unstructured":"Zaborin A, Krezalek M, Hyoju S et al (2017) Critical role of microbiota within cecal crypts on the regenerative capacity of the intestinal epithelium following surgical stress. Am J Physiol Gastrointest Liver Physiol 312:G112\u2013G122","journal-title":"Am J Physiol Gastrointest Liver Physiol"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00284-018-1471-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-018-1471-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-018-1471-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T07:59:05Z","timestamp":1604131145000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00284-018-1471-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,10]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["1471"],"URL":"https:\/\/doi.org\/10.1007\/s00284-018-1471-7","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"value":"0343-8651","type":"print"},{"value":"1432-0991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,10]]},"assertion":[{"value":"17 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}