{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T15:16:25Z","timestamp":1768403785876,"version":"3.49.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1007\/s00284-021-02460-6","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T05:07:17Z","timestamp":1616648837000},"page":"1807-1812","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Zearalenone Adsorbent Based on a Lyophilized Indigenous Bacterial Lactobacillus plantarum Strain as Feed Additive for Pigs: A Preliminary Study In Vivo"],"prefix":"10.1007","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-2686","authenticated-orcid":false,"given":"Mar\u00eda F.","family":"Vega","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana N.","family":"Di\u00e9guez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Riccio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda O.","family":"Tapia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia N.","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"2460_CR1","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s40813-018-0095-4","volume":"4","author":"I Hennig-Pauka","year":"2018","unstructured":"Hennig-Pauka I, Koch FJ, Schaumberger S, Woechtl B, Novak J, Sulyok M, Nagl V (2018) Current challenges in the diagnosis of zearalenone toxicosis as illustrated by a field case of hyperestrogenism in suckling piglets. Porcine Health Manag 4:18. https:\/\/doi.org\/10.1186\/s40813-018-0095-4","journal-title":"Porcine Health Manag"},{"issue":"9","key":"2460_CR2","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/0278-6915(87)90101-3","volume":"25","author":"M Olsen","year":"1987","unstructured":"Olsen M, Pettersson H, Sandholm K, Visconti A, Kiessling KH (1987) Metabolism of zearalenone by sow intestinal mucosa in vitro. Food Chem Toxicol 25(9):681\u2013683. https:\/\/doi.org\/10.1016\/0278-6915(87)90101-3","journal-title":"Food Chem Toxicol"},{"issue":"1","key":"2460_CR3","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.tvjl.2005.03.004","volume":"172","author":"H Malekinejad","year":"2006","unstructured":"Malekinejad H, Maas-Bakker R, Fink-Gremmels J (2006) Species differences in the hepatic biotransformation of zearalenone. Vet J 172(1):96\u2013102. https:\/\/doi.org\/10.1016\/j.tvjl.2005.03.004","journal-title":"Vet J"},{"key":"2460_CR4","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/B978-0-12-415759-0.00039-X","volume-title":"Haschek and Rousseaux\u2019s handbook of toxicologic pathology","author":"WM Haschek","year":"2013","unstructured":"Haschek WM, Voss KA (2013) Mycotoxins. In: Haschek WM, Rousseaux CR, Wallig MA (eds) Haschek and Rousseaux\u2019s handbook of toxicologic pathology, vol II, 3rd edn. Academic Press, Elsevier, pp 1187\u20131258","edition":"3"},{"issue":"37","key":"2460_CR5","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1055\/s-0032-1305295","volume":"137","author":"V Andresen","year":"2012","unstructured":"Andresen V, Layer P, Menge D, Keller J (2012) Efficacy of freeze-dried Lactobacilli in functional diarrhoe: a pilot study. Dtsch Med Wochenschr 137(37):1792\u20131796. https:\/\/doi.org\/10.1055\/s-0032-1305295","journal-title":"Dtsch Med Wochenschr"},{"issue":"1","key":"2460_CR6","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1111\/jam.13438","volume":"123","author":"BD Chaves","year":"2017","unstructured":"Chaves BD, Brashears MM, Nightingale KK (2017) Applications and safety considerations of Lactobacillus salivarius as a probiotic in animal and human health. J Appl Microbiol 123(1):18\u201328. https:\/\/doi.org\/10.1111\/jam.13438","journal-title":"J Appl Microbiol"},{"issue":"1","key":"2460_CR7","doi-asserted-by":"publisher","first-page":"11","DOI":"10.2174\/1573401313666170517165500","volume":"14","author":"R Massoud","year":"2018","unstructured":"Massoud R, Cruz A, K. DK, (2018) Ochratoxin A: from safety aspects to prevention and remediation strategies. Curr Nutr Food Sci 14(1):11\u201316","journal-title":"Curr Nutr Food Sci"},{"issue":"4","key":"2460_CR8","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1111\/jam.14172","volume":"124","author":"A Zoghi","year":"2018","unstructured":"Zoghi A, Khosravi K, Sohrabvandi S, Attar H (2018) Patulin removal from synbiotic apple juice using Lactobacillus plantarum ATCC 8014. J Appl Microbiol 124(4):1149\u20131160","journal-title":"J Appl Microbiol"},{"issue":"1","key":"2460_CR9","doi-asserted-by":"publisher","first-page":"84","DOI":"10.2174\/1389557513666131211105554","volume":"14","author":"A Zoghi","year":"2014","unstructured":"Zoghi A, Khosravi-Darani K, Sohrabvandi S (2014) Surface binding of toxins and heavy metals by probiotics. Mini Rev Med Chem 14(1):84\u201398. https:\/\/doi.org\/10.2174\/1389557513666131211105554","journal-title":"Mini Rev Med Chem"},{"issue":"8","key":"2460_CR10","doi-asserted-by":"publisher","first-page":"2601","DOI":"10.1002\/jsfa.8082","volume":"97","author":"A Zoghi","year":"2017","unstructured":"Zoghi A, Khosravi-Darani K, Sohrabvandi S, Attar H, Alavi SA (2017) Effect of probiotics on patulin removal from synbiotic apple juice. J Sci Food Agric 97(8):2601\u20132609. https:\/\/doi.org\/10.1002\/jsfa.8082","journal-title":"J Sci Food Agric"},{"issue":"5","key":"2460_CR11","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.3390\/toxins2051078","volume":"2","author":"L Abrunhosa","year":"2010","unstructured":"Abrunhosa L, Paterson RR, Venancio A (2010) Biodegradation of ochratoxin a for food and feed decontamination. Toxins 2(5):1078\u20131099. https:\/\/doi.org\/10.3390\/toxins2051078","journal-title":"Toxins"},{"issue":"2","key":"2460_CR12","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s12602-017-9350-2","volume":"10","author":"EZ Gomaa","year":"2018","unstructured":"Gomaa EZ, Abdelall MF, El-Mahdy OM (2018) Detoxification of Aflatoxin B1 by antifungal compounds from Lactobacillus brevis and Lactobacillus paracasei, isolated from dairy products. Probiotics Antimicrob Proteins 10(2):201\u2013209. https:\/\/doi.org\/10.1007\/s12602-017-9350-2","journal-title":"Probiotics Antimicrob Proteins"},{"key":"2460_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-018-9512-x","author":"A Chlebicz","year":"2019","unstructured":"Chlebicz A, Slizewska K (2019) In vitro detoxification of aflatoxin B1, deoxynivalenol, fumonisins, T-2 toxin and zearalenone by probiotic bacteria from genus Lactobacillus and Saccharomyces cerevisiae yeast. Probiotics Antimicrob Proteins. https:\/\/doi.org\/10.1007\/s12602-018-9512-x","journal-title":"Probiotics Antimicrob Proteins"},{"issue":"7","key":"2460_CR14","doi-asserted-by":"publisher","first-page":"3545","DOI":"10.1128\/aem.68.7.3545-3549.2002","volume":"68","author":"H El-Nezami","year":"2002","unstructured":"El-Nezami H, Polychronaki N, Salminen S, Mykkanen H (2002) Binding rather than metabolism may explain the interaction of two food-Grade Lactobacillus strains with zearalenone and its derivative (')alpha-earalenol. Appl Environ Microbiol 68(7):3545\u20133549. https:\/\/doi.org\/10.1128\/aem.68.7.3545-3549.2002","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"2460_CR15","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.bjm.2017.05.001","volume":"48","author":"MF Vega","year":"2017","unstructured":"Vega MF, Dieguez SN, Riccio B, Aranguren S, Giordano A, Denzoin L, Soraci AL, Tapia MO, Ross R, Apas A, Gonzalez SN (2017) Zearalenone adsorption capacity of lactic acid bacteria isolated from pigs. Braz J Microbiol 48(4):715\u2013723. https:\/\/doi.org\/10.1016\/j.bjm.2017.05.001","journal-title":"Braz J Microbiol"},{"issue":"3","key":"2460_CR16","doi-asserted-by":"publisher","first-page":"613","DOI":"10.4315\/0362-028X-68.3.613","volume":"68","author":"DJ Bueno","year":"2005","unstructured":"Bueno DJ, Di Marco L, Oliver G, Bardon A (2005) In vitro binding of zearalenone to different adsorbents. J Food Prot 68(3):613\u2013615","journal-title":"J Food Prot"},{"issue":"14","key":"2460_CR17","doi-asserted-by":"publisher","first-page":"4577","DOI":"10.1021\/jf049924m","volume":"52","author":"H El-Nezami","year":"2004","unstructured":"El-Nezami H, Polychronaki N, Lee YK, Haskard C, Juvonen R, Salminen S, Mykkanen H (2004) Chemical moieties and interactions involved in the binding of zearalenone to the surface of Lactobacillus rhamnosus strains GG. J Agric Food Chem 52(14):4577\u20134581. https:\/\/doi.org\/10.1021\/jf049924m","journal-title":"J Agric Food Chem"},{"issue":"4","key":"2460_CR18","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1080\/1745039X.2014.927709","volume":"68","author":"MB Riccio","year":"2014","unstructured":"Riccio MB, Tapia MO, Martinez G, Aranguren SM, Dieguez SN, Soraci AL, Rodriguez E (2014) Effect of the combination of crude extracts of Penicillium griseofulvum and Fusarium graminearum containing patulin and zearalenone on rumen microbial fermentation and on their metabolism in continuous culture fermenters. Arch Anim Nutr 68(4):309\u2013319. https:\/\/doi.org\/10.1080\/1745039X.2014.927709","journal-title":"Arch Anim Nutr"},{"issue":"1","key":"2460_CR19","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1080\/02652030110053426","volume":"19","author":"B Odhav","year":"2002","unstructured":"Odhav B, Naicker V (2002) Mycotoxins in South African traditionally brewed beers. Food Addit Contam 19(1):55\u201361. https:\/\/doi.org\/10.1080\/02652030110053426","journal-title":"Food Addit Contam"},{"issue":"4","key":"2460_CR20","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.riam.2009.03.003","volume":"26","author":"MB Roige","year":"2009","unstructured":"Roige MB, Aranguren SM, Riccio MB, Pereyra S, Soraci AL, Tapia MO (2009) Mycobiota and mycotoxins in fermented feed, wheat grains and corn grains in Southeastern Buenos Aires Province Argentina. Rev Iberoam Micol 26(4):233\u2013237","journal-title":"Rev Iberoam Micol"},{"issue":"1","key":"2460_CR21","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/2049-1891-5-37","volume":"5","author":"X Li","year":"2014","unstructured":"Li X, Zhao L, Fan Y, Jia Y, Sun L, Ma S, Ji C, Ma Q, Zhang J (2014) Occurrence of mycotoxins in feed ingredients and complete feeds obtained from the Beijing region of China. J Anim Sci Biotechnol 5(1):37. https:\/\/doi.org\/10.1186\/2049-1891-5-37","journal-title":"J Anim Sci Biotechnol"},{"key":"2460_CR22","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/1746-6148-8-89","volume":"8","author":"C Suo","year":"2012","unstructured":"Suo C, Yin Y, Wang X, Lou X, Song D, Wang X, Gu Q (2012) Effects of Lactobacillus plantarum ZJ316 on pig growth and pork quality. BMC Vet Res 8:89. https:\/\/doi.org\/10.1186\/1746-6148-8-89","journal-title":"BMC Vet Res"},{"key":"2460_CR23","doi-asserted-by":"publisher","DOI":"10.1002\/9780470995624","volume-title":"Whittemore\u2019s science and practice of pig production","author":"A Kyriazakis","year":"2006","unstructured":"Kyriazakis A, Whittemore CT (2006) Whittemore\u2019s science and practice of pig production. Blackwell, Oxford"},{"issue":"2","key":"2460_CR24","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.jchromb.2006.06.012","volume":"843","author":"P Songsermsakul","year":"2006","unstructured":"Songsermsakul P, Sontag G, Cichna-Markl M, Zentek J, Razzazi-Fazeli E (2006) Determination of zearalenone and its metabolites in urine, plasma and faeces of horses by HPLC-APCI-MS. J Chromatogr B 843(2):252\u2013261. https:\/\/doi.org\/10.1016\/j.jchromb.2006.06.012","journal-title":"J Chromatogr B"},{"issue":"6","key":"2460_CR25","doi-asserted-by":"publisher","first-page":"944","DOI":"10.3109\/08923973.2012.674139","volume":"34","author":"S Abbes","year":"2012","unstructured":"Abbes S, Ben Salah-Abbes J, Sharafi H, Noghabi KA, Oueslati R (2012) Interaction of Lactobacillus plantarum MON03 with Tunisian montmorillonite clay and ability of the composite to immobilize zearalenone in vitro and counteract immunotoxicity in vivo. Immunopharmacol Immunotoxicol 34(6):944\u2013950. https:\/\/doi.org\/10.3109\/08923973.2012.674139","journal-title":"Immunopharmacol Immunotoxicol"},{"issue":"1","key":"2460_CR26","first-page":"33","volume":"15","author":"J Bauer","year":"1987","unstructured":"Bauer J, Heinritzi K, Gareis M, Gedek B (1987) Changes in the genital tract of female swine after feeding with practice-relevant amounts of zearalenone. Tierarztl Prax 15(1):33\u201336","journal-title":"Tierarztl Prax"},{"issue":"3","key":"2460_CR27","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/0273-2300(87)90037-7","volume":"7","author":"T Kuiper-Goodman","year":"1987","unstructured":"Kuiper-Goodman T, Scott PM, Watanabe H (1987) Risk assessment of the mycotoxin zearalenone. Regul Toxicol Pharmacol 7(3):253\u2013306","journal-title":"Regul Toxicol Pharmacol"},{"issue":"12","key":"2460_CR28","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1080\/09553002.2019.1524990","volume":"94","author":"MH Sanad","year":"2018","unstructured":"Sanad MH, Fouzy ASM, Sobhy HM, Hathout AS, Hussain OA (2018) Tracing the protective activity of Lactobacillus plantarum using technetium-(99m)-labeled zearalenone for organ toxicity. Int J Radiat Biol 94(12):1151\u20131158. https:\/\/doi.org\/10.1080\/09553002.2019.1524990","journal-title":"Int J Radiat Biol"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-021-02460-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-021-02460-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-021-02460-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T03:54:26Z","timestamp":1619754866000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-021-02460-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,25]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["2460"],"URL":"https:\/\/doi.org\/10.1007\/s00284-021-02460-6","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"value":"0343-8651","type":"print"},{"value":"1432-0991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,25]]},"assertion":[{"value":"16 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"These studies were authorized by the Ethics Committee of the Graduate Department of the Faculty of Biochemistry, Chemistry and Pharmacy of National University of Tucum\u00e1n, and this situation was supported by the defence of my Thesis.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}