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We aimed to analyze the relationship between <jats:italic>Blastocystis<\/jats:italic> subtypes ST1-4 and 7, the <jats:italic>Firmicutes<\/jats:italic> to <jats:italic>Bacteroidetes<\/jats:italic> ratio (<jats:italic>F\/B<\/jats:italic> ratio) of fecal microbiota, and chronic stress in university students. This study had a cross-sectional design with a sample of 202 students. We analyzed fecal and hair samples, and stress inventories were applied to the students. The results showed a frequency of <jats:italic>Blastocystis<\/jats:italic>-colonized students of 52.97%. Regarding fecal microbiota, a median RAU of 0.801 for <jats:italic>Firmicutes<\/jats:italic> and 0.82 of <jats:italic>Bacteroidetes<\/jats:italic> were obtained, with an <jats:italic>F\/B<\/jats:italic> ratio of 0.83. A low <jats:italic>F\/B<\/jats:italic> ratio (66.04%) was more frequent in <jats:italic>Blastocystis<\/jats:italic>-colonized students, whereas a high <jats:italic>F\/B<\/jats:italic> ratio (68.09%) (<jats:italic>p<\/jats:italic>\u2009=\u2009\u2009&lt;\u20090.0001) was found in the <jats:italic>Blastocystis<\/jats:italic>-non-colonized. Only <jats:italic>Blastocystis<\/jats:italic> ST3 did not significantly correlate with a low <jats:italic>F\/B<\/jats:italic> ratio (<jats:italic>p<\/jats:italic>\u2009=\u20090.290). The ST4 was associated with lower values of cortisol (<jats:italic>p<\/jats:italic>\u2009=\u20090.030), psychological stress (<jats:italic>p<\/jats:italic>\u2009=\u20090.040), and lower frequency of constipation (<jats:italic>p<\/jats:italic>\u2009=\u20090.010). Only two students with the ST1 had abdominal pain (<jats:italic>p<\/jats:italic>\u2009=\u20090.007). Our results suggest that colonization by <jats:italic>Blastocystis<\/jats:italic> subtypes can modify the intestinal microbiota due to a decreased ratio between the two most representative phyla <jats:italic>(F\/B).<\/jats:italic> Also, the results of this study show that ST4 colonization is related to a lower level of chronic stress.<\/jats:p>\n                <jats:p><jats:bold>Graphical abstract<\/jats:bold><\/jats:p>","DOI":"10.1007\/s00284-021-02756-7","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T04:34:59Z","timestamp":1642998899000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Relationship Among Blastocystis, the Firmicutes\/Bacteroidetes Ratio and Chronic Stress in Mexican University Students"],"prefix":"10.1007","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5597-182X","authenticated-orcid":false,"given":"Janeth Oliva","family":"Guangorena-G\u00f3mez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iliana Itzel","family":"Lozano-Ochoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0712-8053","authenticated-orcid":false,"given":"Ilse Lizeth","family":"Rivera-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5686-7821","authenticated-orcid":false,"given":"Alejandra","family":"M\u00e9ndez-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9090-6049","authenticated-orcid":false,"given":"Jorge Antonio","family":"Espinosa-Fematt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Mu\u00f1oz-Y\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,24]]},"reference":[{"key":"2756_CR1","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1007\/s10096-017-2965-0","volume":"36","author":"M Lepczy\u0144ska","year":"2017","unstructured":"Lepczy\u0144ska M, Bia\u0142kowska J, Dzika E et al (2017) Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity? 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