{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:43:07Z","timestamp":1740109387515,"version":"3.37.3"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100008973","name":"University of Kurdistan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008973","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1007\/s00284-022-02775-y","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T08:03:24Z","timestamp":1645603404000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sirt3, 6, and 7 Genes Expression in Gastric Antral Epithelial Cells of Patients with Helicobacter pylori Infection"],"prefix":"10.1007","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0654-8918","authenticated-orcid":false,"given":"Manouchehr Ahmadi","family":"Hedayati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8749-811X","authenticated-orcid":false,"given":"Delniya","family":"Khani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-5032","authenticated-orcid":false,"given":"Farshad","family":"Sheikhesmaeili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,23]]},"reference":[{"issue":"4","key":"2775_CR1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/nrm3293","volume":"13","author":"RH Houtkooper","year":"2012","unstructured":"Houtkooper RH, Pirinen E, Auwerx J (2012) Sirtuins as regulators of metabolism and healthspan. Nat Rev Mol Cell Biol 13(4):225\u2013238","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"1","key":"2775_CR2","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1186\/s13046-016-0461-5","volume":"35","author":"Z Mei","year":"2016","unstructured":"Mei Z, Zhang X, Yi J, Huang J, He J, Tao Y (2016) Sirtuins in metabolism, DNA repair, and cancer. J Exp Clin Cancer Res 35(1):182","journal-title":"J Exp Clin Cancer Res"},{"key":"2775_CR3","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.semcdb.2015.07.008","volume":"43","author":"C Sebastian","year":"2015","unstructured":"Sebastian C, Mostoslavsky R (2015) The role of mammalian sirtuins in cancer metabolism. Semin Cell Dev Biol 43:33\u201342","journal-title":"Semin Cell Dev Biol"},{"key":"2775_CR4","doi-asserted-by":"publisher","first-page":"235754","DOI":"10.4061\/2011\/235754","volume":"2011","author":"D McGuinness","year":"2011","unstructured":"McGuinness D, McGuinness DH, McCaul JA, Shiels PG (2011) Sirtuins, bioageing, and cancer. J Aging Res 2011:235754","journal-title":"J Aging Res"},{"key":"2775_CR5","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.1016\/j.ddtec.2012.08.003","volume":"12","author":"W Dang","year":"2014","unstructured":"Dang W (2014) The controversial world of sirtuins. Drug Discov Today Technol 12:e9\u2013e17. https:\/\/doi.org\/10.1016\/j.ddtec.2012.08.003","journal-title":"Drug Discov Today Technol"},{"issue":"2","key":"2775_CR6","first-page":"1938","volume":"8","author":"Q Geng","year":"2015","unstructured":"Geng Q, Peng H, Chen F, Luo R, Li R (2015) High expression of Sirt7 served as a predictor of adverse outcome in breast cancer. Int J Clin Exp Pathol 8(2):1938\u20131945","journal-title":"Int J Clin Exp Pathol"},{"issue":"3","key":"2775_CR7","first-page":"245","volume":"15","author":"G Kelly","year":"2010","unstructured":"Kelly G (2010) A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1. Altern Med Rev 15(3):245\u2013263","journal-title":"Altern Med Rev"},{"issue":"12","key":"2775_CR8","doi-asserted-by":"publisher","first-page":"1949","DOI":"10.3390\/cancers11121949","volume":"11","author":"E Zhao","year":"2019","unstructured":"Zhao E, Hou J, Ke X, Abbas MN, Kausar S, Zhang L et al (2019) The roles of sirtuin family proteins in cancer progression. Cancers 11(12):1949","journal-title":"Cancers"},{"issue":"10","key":"2775_CR9","doi-asserted-by":"publisher","first-page":"645","DOI":"10.3109\/07357907.2013.853076","volume":"31","author":"MV de Oliveira","year":"2013","unstructured":"de Oliveira MV, Andrade JM, Paraiso AF, Santos SH (2013) Sirtuins and cancer: new insights and cell signaling. Cancer Investig 31(10):645\u2013653","journal-title":"Cancer Investig"},{"issue":"3\u20134","key":"2775_CR10","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s13148-010-0008-0","volume":"1","author":"S Voelter-Mahlknecht","year":"2010","unstructured":"Voelter-Mahlknecht S, Mahlknecht U (2010) The sirtuins in the pathogenesis of cancer. Clin Epigenet 1(3\u20134):71\u201383","journal-title":"Clin Epigenet"},{"key":"2775_CR11","doi-asserted-by":"publisher","first-page":"38","DOI":"10.3389\/fphar.2019.00038","volume":"10","author":"V Carafa","year":"2019","unstructured":"Carafa V, Altucci L, Nebbioso A (2019) Dual tumor suppressor and tumor promoter action of sirtuins in determining malignant phenotype. Front Pharmacol 10:38","journal-title":"Front Pharmacol"},{"key":"2775_CR12","doi-asserted-by":"publisher","first-page":"239","DOI":"10.2147\/CMAR.S149619","volume":"10","author":"R Sitarz","year":"2018","unstructured":"Sitarz R, Skierucha M, Mielko J, Offerhaus GJA, Maciejewski R, Polkowski WP (2018) Gastric cancer: epidemiology, prevention, classification, and treatment. Cancer Manag Res 10:239\u2013248. https:\/\/doi.org\/10.2147\/CMAR.S149619 (Published 7 Feb 2018)","journal-title":"Cancer Manag Res"},{"issue":"1","key":"2775_CR13","doi-asserted-by":"publisher","first-page":"43","DOI":"10.30699\/ijmm.14.1.43","volume":"14","author":"M Ahmadi Hedayati","year":"2020","unstructured":"Ahmadi Hedayati M, Khani D (2020) Relationship of social risk factors and Helicobacter pylori infection with pathological characteristics of gastric carcinoma. Iran J Med Microbiol 14(1):43\u201330","journal-title":"Iran J Med Microbiol"},{"issue":"2","key":"2775_CR14","doi-asserted-by":"publisher","first-page":"543","DOI":"10.3892\/ol.2016.5506","volume":"13","author":"XY Zhang","year":"2017","unstructured":"Zhang XY, Zhang PY, Aboul-Soud MA (2017) From inflammation to gastric cancer: role of Helicobacter pylori. Oncol Lett 13(2):543\u2013548. https:\/\/doi.org\/10.3892\/ol.2016.5506","journal-title":"Oncol Lett"},{"issue":"Suppl 1","key":"2775_CR15","first-page":"8","volume":"20","author":"DN Ouras","year":"2015","unstructured":"Ouras DN, Trang TTH, Yamaoka Y (2015) Pathogenesis of Helicobacter pylori infection. Helicobacter 20(Suppl 1):8\u201316","journal-title":"Helicobacter"},{"key":"2775_CR16","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3389\/fmicb.2010.00115","volume":"1","author":"KR Jones","year":"2010","unstructured":"Jones KR, Whitmire JM, Merrell DS (2010) A tale of two toxins: Helicobacter pylori CagA and VacA modulate host pathways that impact disease. Front Microbiol 1:115","journal-title":"Front Microbiol"},{"issue":"34","key":"2775_CR17","doi-asserted-by":"publisher","first-page":"5685","DOI":"10.3748\/wjg.v19.i34.5685","volume":"19","author":"F Vaziri","year":"2013","unstructured":"Vaziri F, Najar Peerayeh S, Alebouyeh M et al (2013) Diversity of Helicobacter pylori genotypes in Iranian patients with different gastroduodenal disorders. World J Gastroenterol 19(34):5685\u20135692. https:\/\/doi.org\/10.3748\/wjg.v19.i34.5685","journal-title":"World J Gastroenterol"},{"key":"2775_CR18","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/1478-811X-9-28","volume":"9","author":"S Backert","year":"2011","unstructured":"Backert S, Clyne M, Tegtmeyer N (2011) Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori. Cell Commun Signal 9:28","journal-title":"Cell Commun Signal"},{"key":"2775_CR19","doi-asserted-by":"publisher","first-page":"737621","DOI":"10.1155\/2015\/737621","volume":"2015","author":"S Sue","year":"2015","unstructured":"Sue S, Shibata W, Maeda S (2015) Helicobacter pylori-induced signaling pathways contribute to intestinal metaplasia and gastric carcinogenesis. BioMed Res Int 2015:737621","journal-title":"BioMed Res Int"},{"issue":"4","key":"2775_CR20","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3390\/toxins9040115","volume":"9","author":"S Backert","year":"2017","unstructured":"Backert S, Tegtmeyer N (2017) Type IV secretion and signal transduction of Helicobacter pylori CagA through interactions with host cell receptors. Toxins 9(4):115","journal-title":"Toxins"},{"key":"2775_CR21","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8167273","author":"VT Vachharajani","year":"2016","unstructured":"Vachharajani VT, Liu T, Wang X, Hoth JJ, Yoza BK, McCall CE (2016) Sirtuins link inflammation and metabolism. J Immunol Res. https:\/\/doi.org\/10.1155\/2016\/8167273","journal-title":"J Immunol Res"},{"issue":"19","key":"2775_CR22","doi-asserted-by":"publisher","first-page":"343","DOI":"10.3238\/arztebl.2010.0343","volume":"107","author":"JB du Prel","year":"2010","unstructured":"du Prel JB, R\u00f6hrig B, Hommel G, Blettner M (2010) Choosing statistical tests: part 12 of a series on evaluation of scientific publications. Dtsch Arztebl Int 107(19):343\u2013348. https:\/\/doi.org\/10.3238\/arztebl.2010.0343","journal-title":"Dtsch Arztebl Int"},{"issue":"2","key":"2775_CR23","doi-asserted-by":"publisher","first-page":"85","DOI":"10.4103\/0301-4738.77005","volume":"59","author":"BK Nayak","year":"2011","unstructured":"Nayak BK, Hazra A (2011) How to choose the right statistical test? Indian J Ophthalmol 59(2):85\u201386. https:\/\/doi.org\/10.4103\/0301-4738.77005","journal-title":"Indian J Ophthalmol"},{"key":"2775_CR24","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.micpath.2017.12.078","volume":"116","author":"S Zandi","year":"2018","unstructured":"Zandi S, Hedayati MA, Mohammadi E, Sheikhesmaeili F (2018) Helicobacter pylori infection increases sirt2 gene expression in gastric epithelial cells of gastritis patients. Microb Pathog 116:120\u2013123","journal-title":"Microb Pathog"},{"issue":"4","key":"2775_CR25","first-page":"913","volume":"19","author":"S Mohammadi Saravle","year":"2018","unstructured":"Mohammadi Saravle S, Ahmadi Hedayati M, Mohammadi E, Sheikhesmaeili F, Nikkhou B (2018) Sirt1 gene expression and gastric epithelial cells tumor stage in patients with Helicobacter pylori infection. Asian Pac J Cancer Prev 19(4):913\u2013916","journal-title":"Asian Pac J Cancer Prev"},{"issue":"11","key":"2775_CR26","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1007\/s00109-006-0097-6","volume":"84","author":"JH Schefe","year":"2006","unstructured":"Schefe JH, Lehmann KE, Buschmann IR, Unger T, Funke-Kaiser H (2006) Quantitative real-time RT-PCR data analysis: current concepts and the novel \u201cgene expression\u2019s CT difference\u201d formula. J Mol Med (Berl) 84(11):901\u2013910. https:\/\/doi.org\/10.1007\/s00109-006-0097-6 (Epub 14 Sep 2006)","journal-title":"J Mol Med (Berl)"},{"key":"2775_CR27","doi-asserted-by":"publisher","first-page":"17771","DOI":"10.1074\/jbc.270.30.17771","volume":"270","author":"JC Atherton","year":"1995","unstructured":"Atherton JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ, Cover TL (1995) Cover Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 270:17771\u201317777","journal-title":"J Biol Chem"},{"issue":"1","key":"2775_CR28","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/S0016-5085(98)70365-8","volume":"115","author":"LJ van Doorn","year":"1998","unstructured":"van Doorn LJ, Figueiredo C, Sanna R, Plaisier A, Schneeberger P, de Boer W et al (1998) Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 115(1):58\u201366","journal-title":"Gastroenterology"},{"issue":"2","key":"2775_CR29","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/j.1523-5378.2011.00919.x","volume":"17","author":"LA Sicinschi","year":"2012","unstructured":"Sicinschi LA, Correa P, Bravo LE et al (2012) Non-invasive genotyping of Helicobacter pylori cagA, vacA, and hopQ from asymptomatic children. Helicobacter 17(2):96\u2013106","journal-title":"Helicobacter"},{"issue":"39","key":"2775_CR30","doi-asserted-by":"publisher","first-page":"6615","DOI":"10.1038\/s41388-019-0894-3","volume":"38","author":"W-B Ou","year":"2019","unstructured":"Ou W-B, Ni N, Zuo R, Zhuang W, Zhu M, Kyriazoglou A et al (2019) Cyclin D1 is a mediator of gastrointestinal stromal tumor KIT-independence. Oncogene 38(39):6615\u20136629","journal-title":"Oncogene"},{"issue":"8","key":"2775_CR31","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1111\/bph.13861","volume":"175","author":"G Meng","year":"2018","unstructured":"Meng G, Liu J, Liu S et al (2018) Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner. Br J Pharmacol 175(8):1126\u20131145. https:\/\/doi.org\/10.1111\/bph.13861","journal-title":"Br J Pharmacol"},{"key":"2775_CR32","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1478-811X-11-77","volume":"11","author":"G Posselt","year":"2013","unstructured":"Posselt G, Backert S, Wessler S (2013) The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal 11:77","journal-title":"Cell Commun Signal"},{"issue":"11","key":"2775_CR33","doi-asserted-by":"publisher","first-page":"677","DOI":"10.3390\/toxins11110677","volume":"11","author":"S Ansari","year":"2019","unstructured":"Ansari S, Yamaoka Y (2019) Helicobacter pylori virulence factors exploiting gastric colonization and its pathogenicity. Toxins 11(11):677","journal-title":"Toxins"},{"issue":"9","key":"2775_CR34","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1016\/j.bbadis.2015.07.001","volume":"1852","author":"A Magalh\u00e3es","year":"2015","unstructured":"Magalh\u00e3es A, Marcos-Pinto R, Nairn AV, Dela Rosa M, Ferreira RM, Junqueira-Neto S et al (2015) Helicobacter pylori chronic infection and mucosal inflammation switches the human gastric glycosylation pathways. Biochim Biophys Acta 1852(9):1928\u20131939","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"2775_CR35","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.3390\/biology2031110","volume":"2","author":"M Oleastro","year":"2013","unstructured":"Oleastro M, M\u00e9nard A (2013) The role of Helicobacter pylori outer membrane proteins in adherence and pathogenesis. Biology 2(3):1110\u20131134","journal-title":"Biology"},{"key":"2775_CR36","doi-asserted-by":"publisher","first-page":"426309","DOI":"10.1155\/2014\/426309","volume":"2014","author":"B Kalali","year":"2014","unstructured":"Kalali B, Mejias-Luque R, Javaheri A, Gerhard M (2014) H. pylori virulence factors: influence on immune system and pathology. Mediat Inflamm 2014:426309","journal-title":"Mediat Inflamm"},{"issue":"45","key":"2775_CR37","doi-asserted-by":"publisher","first-page":"78365","DOI":"10.18632\/oncotarget.18695","volume":"8","author":"DY Lee","year":"2017","unstructured":"Lee DY, Jung DE, Yu SS, Lee YS, Choi BK, Lee YC (2017) Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer by Helicobacter pylori oncoprotein CagA. OncoTarget 8(45):78365\u201378378. https:\/\/doi.org\/10.18632\/oncotarget.18695 (Published 27 June 2017)","journal-title":"OncoTarget"},{"issue":"7","key":"2775_CR38","first-page":"710","volume":"22","author":"R Xia","year":"2019","unstructured":"Xia R, Zhang B, Wang X, Jia Q (2019) Pathogenic interactions between Helicobacter pylori adhesion protein HopQ and human cell surface adhesion molecules CEACAMs in gastric epithelial cells. Iran J Basic Med Sci 22(7):710\u2013715","journal-title":"Iran J Basic Med Sci"},{"issue":"4","key":"2775_CR39","doi-asserted-by":"publisher","first-page":"e1553487","DOI":"10.1080\/2162402X.2018.1553487","volume":"8","author":"C Gur","year":"2019","unstructured":"Gur C, Maalouf N, Gerhard M, Singer BB, Emg\u00e5rd J, Temper V et al (2019) The Helicobacter pylori HopQ outer-membrane protein inhibits immune cell activities. Oncoimmunology 8(4):e1553487","journal-title":"Oncoimmunology"},{"issue":"13","key":"2775_CR40","doi-asserted-by":"publisher","first-page":"e98665","DOI":"10.15252\/embj.201798665","volume":"37","author":"K Moonens","year":"2018","unstructured":"Moonens K, Hamway Y, Neddermann M, Reschke M, Tegtmeyer N, Kruse T et al (2018) Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAMs. EMBO J 37(13):e98665","journal-title":"EMBO J"},{"key":"2775_CR41","doi-asserted-by":"publisher","first-page":"2135","DOI":"10.3389\/fimmu.2019.02135","volume":"10","author":"O Silva-Garc\u00eda","year":"2019","unstructured":"Silva-Garc\u00eda O, Valdez-Alarc\u00f3n JJ, Baizabal-Aguirre VM (2019) Wnt\/\u03b2-catenin signaling as a molecular target by pathogenic bacteria. Front Immunol 10:2135","journal-title":"Front Immunol"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-02775-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-022-02775-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-02775-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T19:09:15Z","timestamp":1647544155000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-022-02775-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,23]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["2775"],"URL":"https:\/\/doi.org\/10.1007\/s00284-022-02775-y","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"type":"print","value":"0343-8651"},{"type":"electronic","value":"1432-0991"}],"subject":[],"published":{"date-parts":[[2022,2,23]]},"assertion":[{"value":"16 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors, Manouchehr Ahmadi Hedayati, Delniya Khani, and Farshad Sheikhesmaeili, declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The ethical clearance (IR.MUK.REC. 2018-07-17) for the study was obtained from Kurdistan University of Medical Sciences.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}],"article-number":"114"}}