{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:51:39Z","timestamp":1773787899337,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"DBT","award":["BT\/RLF\/Re-entry\/09\/2019"],"award-info":[{"award-number":["BT\/RLF\/Re-entry\/09\/2019"]}]},{"name":"Department of Science and Technology","award":["JCB-41"],"award-info":[{"award-number":["JCB-41"]}]},{"DOI":"10.13039\/501100009053","name":"The Wellcome Trust DBT India Alliance","doi-asserted-by":"publisher","award":["IA\/E\/18\/1\/504307"],"award-info":[{"award-number":["IA\/E\/18\/1\/504307"]}],"id":[{"id":"10.13039\/501100009053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s00284-022-03094-y","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T01:11:28Z","timestamp":1669165888000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Structural Profiles of SARS-CoV-2 Variants in India"],"prefix":"10.1007","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7384-690X","authenticated-orcid":false,"given":"Soumyananda","family":"Chakraborti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmita","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritu","family":"Goswami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anmol","family":"Chandele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,22]]},"reference":[{"issue":"4","key":"3094_CR1","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/S2213-2600(21)00075-8","volume":"9","author":"TC Williams","year":"2021","unstructured":"Williams TC, Burgers WA (2021) SARS-CoV-2 evolution and vaccines: cause for concern? Lancet Respir Med 9(4):333\u2013335. https:\/\/doi.org\/10.1016\/S2213-2600(21)00075-8","journal-title":"Lancet Respir Med"},{"issue":"6","key":"3094_CR2","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1038\/s41577-021-00556-5","volume":"21","author":"RK Gupta","year":"2021","unstructured":"Gupta RK (2021) Will SARS-CoV-2 variants of concern affect the promise of vaccines? Nat Rev Immunol 21(6):340\u2013341. https:\/\/doi.org\/10.1038\/s41577-021-00556-5","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"3094_CR3","doi-asserted-by":"publisher","first-page":"e80","DOI":"10.1016\/j.jinf.2022.02.005","volume":"84","author":"PD Yadav","year":"2022","unstructured":"Yadav PD, Sapkal GN, Sahay RR, Potdar VA, Deshpande GR, Patil DY et al (2022) Substantial immune response in Omicron infected breakthrough and unvaccinated individuals against SARS-CoV-2 variants of concerns. J Infect 84(5):e80\u2013e81. https:\/\/doi.org\/10.1016\/j.jinf.2022.02.005","journal-title":"J Infect"},{"key":"3094_CR4","doi-asserted-by":"publisher","first-page":"e238","DOI":"10.1016\/S2666-5247(21)00123-3","volume":"2","author":"U Samarasekera","year":"2021","unstructured":"Samarasekera U (2021) India grapples with second wave of COVID-19. Lancet Microbe 2:e238. https:\/\/doi.org\/10.1016\/S2666-5247(21)00123-3","journal-title":"Lancet Microbe"},{"issue":"6","key":"3094_CR5","doi-asserted-by":"publisher","first-page":"2354","DOI":"10.1002\/jmv.27646","volume":"94","author":"PA Desingu","year":"2022","unstructured":"Desingu PA, Nagarajan K (2022) SARS-CoV-2 Omicron variant is spreading in different parts of the world in three different trends. J Med Virol 94(6):2354\u20132356. https:\/\/doi.org\/10.1002\/jmv.27646","journal-title":"J Med Virol"},{"issue":"3","key":"3094_CR6","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/j.dsx.2021.05.009","volume":"15","author":"VK Jain","year":"2021","unstructured":"Jain VK, Iyengar KP, Vaishya R (2021) Differences between First wave and Second wave of COVID-19 in India. Diabetes Metab Syndr 15(3):1047\u20131048. https:\/\/doi.org\/10.1016\/j.dsx.2021.05.009","journal-title":"Diabetes Metab Syndr"},{"issue":"1","key":"3094_CR7","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/s41392-020-0190-2","volume":"5","author":"B Chen","year":"2020","unstructured":"Chen B, Tian E-K, He B, Tian L, Han R, Wang S et al (2020) Overview of lethal human coronaviruses. Signal Transduct Target Ther 5(1):89. https:\/\/doi.org\/10.1038\/s41392-020-0190-2","journal-title":"Signal Transduct Target Ther"},{"key":"3094_CR8","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1038\/s41564-020-0695-z","volume":"5","author":"Coronaviridae Study Group of the International Committee on Taxonomy of Viruses","year":"2020","unstructured":"Coronaviridae Study Group of the International Committee on Taxonomy of Viruses (2020) The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol 5:536\u2013544. https:\/\/doi.org\/10.1038\/s41564-020-0695-z","journal-title":"Nat Microbiol"},{"key":"3094_CR9","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/s41579-020-00459-7","volume":"19","author":"B Hu","year":"2021","unstructured":"Hu B, Guo H, Zhou P, Shi Z-L (2021) Characteristics of SARS-CoV-2 and COVID-19. Nat Rev Microbiol 19:141\u2013154. https:\/\/doi.org\/10.1038\/s41579-020-00459-7","journal-title":"Nat Rev Microbiol"},{"issue":"9","key":"3094_CR10","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1038\/s41401-020-0485-4","volume":"41","author":"Y Huang","year":"2020","unstructured":"Huang Y, Yang C, Xu X, Liu S-W (2020) Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19. Acta Pharmacol Sin 41(9):1141\u20131149. https:\/\/doi.org\/10.1038\/s41401-020-0485-4","journal-title":"Acta Pharmacol Sin"},{"key":"3094_CR11","doi-asserted-by":"publisher","first-page":"587269","DOI":"10.3389\/fcimb.2020.587269","volume":"10","author":"MY Wang","year":"2020","unstructured":"Wang MY, Zhao R, Gao L-J, Gao X-F, Wang D-P, Cao J-M (2020) SARS-CoV-2: structure, biology, and structure-based therapeutics development. Front Cell Infect Microbiol 10:587269. https:\/\/doi.org\/10.3389\/fcimb.2020.587269","journal-title":"Front Cell Infect Microbiol"},{"issue":"6501","key":"3094_CR12","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1126\/science.abb9983","volume":"369","author":"Y Watanabe","year":"2020","unstructured":"Watanabe Y, Allen JD, Wrapp D, McLellan J-S, Crispin M (2020) Site-specific glycan analysis of the SARS-CoV-2 spike. Science 369(6501):330\u2013333. https:\/\/doi.org\/10.1126\/science.abb9983","journal-title":"Science"},{"issue":"7807","key":"3094_CR13","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1038\/s41586-020-2180-5","volume":"581","author":"J Lan","year":"2020","unstructured":"Lan J, Ge J, Yu J, Shan S, Zhou H, Fan S et al (2020) Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE-2 receptor. Nature 581(7807):215\u2013220. https:\/\/doi.org\/10.1038\/s41586-020-2180-5","journal-title":"Nature"},{"issue":"6511","key":"3094_CR14","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1126\/science.abd4251","volume":"369","author":"Y Cai","year":"2020","unstructured":"Cai Y, Zhang J, Xiao T, Peng H, Sterling SM, Walsh RM et al (2020) Distinct conformational states of SARS-CoV-2 spike protein. Science 369(6511):1586\u20131592. https:\/\/doi.org\/10.1126\/science.abd4251","journal-title":"Science"},{"issue":"3","key":"3094_CR15","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/j.cell.2020.09.018","volume":"183","author":"H Yao","year":"2020","unstructured":"Yao H, Song Y, Chen Y, Wu N, Xu J, Sun C et al (2020) Molecular architecture of the SARS-CoV-2 virus. Cell 183(3):730-738.e13. https:\/\/doi.org\/10.1016\/j.cell.2020.09.018","journal-title":"Cell"},{"issue":"8","key":"3094_CR16","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/s41577-021-00578-z","volume":"21","author":"M Sadarangani","year":"2021","unstructured":"Sadarangani M, Marchant A, Kollmann TR (2021) Immunological mechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol 21(8):475\u2013484. https:\/\/doi.org\/10.1038\/s41577-021-00578-z","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"3094_CR17","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/s41392-021-00536-0","volume":"6","author":"C Li","year":"2021","unstructured":"Li C, Tian X, Jia X, Wan J, Lu L, Jiang S et al (2021) The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2. Signal Transduct Target Ther 6(1):132. https:\/\/doi.org\/10.1038\/s41392-021-00536-0","journal-title":"Signal Transduct Target Ther"},{"key":"3094_CR18","doi-asserted-by":"publisher","DOI":"10.1101\/2022.01.24.477633","author":"S Kim","year":"2022","unstructured":"Kim S, Liu Y, Ziarnik M, Cao Y, Zhang F, Im W (2022) Binding of human ACE2 and RBD of Omicron enhanced by unique interaction patterns among SARS-CoV-2 variants of concern. bioRxiv. https:\/\/doi.org\/10.1101\/2022.01.24.477633","journal-title":"bioRxiv"},{"issue":"5","key":"3094_CR19","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1002\/jmv.27585","volume":"94","author":"RK Mahapatra","year":"2022","unstructured":"Mahapatra RK, Tiwari R, Sarangi AK, Sharma SK, Khandia R, Saikumar G et al (2022) Twin combination of Omicron and Delta variants triggering a tsunami wave of ever high surges in COVID-19 cases: a challenging global threat with a special focus on the Indian subcontinent. J Med Virol 94(5):1761\u20131765. https:\/\/doi.org\/10.1002\/jmv.27585","journal-title":"J Med Virol"},{"issue":"3","key":"3094_CR20","doi-asserted-by":"publisher","first-page":"e06564","DOI":"10.1016\/j.heliyon.2021.e06564","volume":"7","author":"S Alai","year":"2021","unstructured":"Alai S, Gujar N, Joshi M, Gautam M, Gairola S (2021) Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein. Heliyon 7(3):e06564. https:\/\/doi.org\/10.1016\/j.heliyon.2021.e06564","journal-title":"Heliyon"},{"issue":"7","key":"3094_CR21","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.3390\/microorganisms9071542","volume":"9","author":"S Cherian","year":"2021","unstructured":"Cherian S, Potdar V, Jadhav S, Yadav P, Gupta N, Das M (2021) SARS-CoV-2 Spike Mutations, L452R, T478K, E484Q and P681R, in the Second Wave of COVID-19 in Maharashtra, India. Microorganisms 9(7):1542. https:\/\/doi.org\/10.3390\/microorganisms9071542","journal-title":"Microorganisms"},{"issue":"10","key":"3094_CR22","doi-asserted-by":"publisher","first-page":"4780","DOI":"10.1002\/jmv.27927","volume":"94","author":"S Kumar","year":"2022","unstructured":"Kumar S, Karuppanan K, Subramaniam G (2022) Omicron (BA.1) and sub-variants (BA.1.1, BA.2, and BA.3) of SARS-CoV-2 spike infectivity and pathogenicity: a comparative sequence and structural-based computational assessment. J Med Virol 94(10):4780\u20134791. https:\/\/doi.org\/10.1002\/jmv.27927","journal-title":"J Med Virol"},{"key":"3094_CR23","doi-asserted-by":"publisher","first-page":"105367","DOI":"10.1016\/j.compbiomed.2022.105367","volume":"144","author":"S Vardhan","year":"2022","unstructured":"Vardhan S, Sahoo SK (2022) Computational studies on the interaction of SARS-CoV-2 Omicron SGp RBD with human receptor ACE2, limonin and glycyrrhizic acid. Comput Biol Med 144:105367. https:\/\/doi.org\/10.1016\/j.compbiomed.2022.105367","journal-title":"Comput Biol Med"},{"issue":"1","key":"3094_CR24","doi-asserted-by":"publisher","first-page":"23622","DOI":"10.1038\/s41598-021-01655-y","volume":"11","author":"MR Rahbar","year":"2021","unstructured":"Rahbar MR, Jahangiri A, Khalili S, Zarei M, Zeinabad KM, Khalesi B et al (2021) Hotspots for mutations in the SARS-CoV-2 spike glycoprotein: a correspondence analysis. Sci Rep 11(1):23622. https:\/\/doi.org\/10.1038\/s41598-021-01655-y","journal-title":"Sci Rep"},{"issue":"7923","key":"3094_CR25","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1038\/d41586-022-02154-4","volume":"608","author":"E Callaway","year":"2022","unstructured":"Callaway E (2022) Will \u201cCentaurus\u201d be the next global coronavirus variant? Indian cases offer clues. Nature 608(7923):462\u2013463. https:\/\/doi.org\/10.1038\/d41586-022-02154-4","journal-title":"Nature"},{"issue":"5","key":"3094_CR26","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1038\/s41423-020-0407-x","volume":"17","author":"P Yang","year":"2020","unstructured":"Yang P, Wang X (2020) COVID-19: a new challenge for human beings. Cell Mol Immunol 17(5):555\u2013557. https:\/\/doi.org\/10.1038\/s41423-020-0407-x","journal-title":"Cell Mol Immunol"},{"issue":"6520","key":"3094_CR27","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1126\/science.abe1502","volume":"370","author":"S Bangaru","year":"2020","unstructured":"Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X et al (2020) Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. Science 370(6520):1089\u20131094. https:\/\/doi.org\/10.1126\/science.abe1502","journal-title":"Science"},{"issue":"5","key":"3094_CR28","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1016\/j.cell.2020.07.012","volume":"182","author":"Q Li","year":"2020","unstructured":"Li Q, Wu J, Nie J, Zhang L, Hao H, Liu S, Zhao C et al (2020) The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity. Cell 182(5):1284-1294.e9. https:\/\/doi.org\/10.1016\/j.cell.2020.07.012","journal-title":"Cell"},{"issue":"7","key":"3094_CR29","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1038\/s41579-021-00573-0","volume":"19","author":"WT Harvey","year":"2021","unstructured":"Harvey WT, Carabelli AM, Jackson B, Gupta RK, Thomson EC, Harrison EC et al (2021) SARS-CoV-2 variants, spike mutations and immune escape. Nat Rev Microbiol 19(7):409\u2013424. https:\/\/doi.org\/10.1038\/s41579-021-00573-0","journal-title":"Nat Rev Microbiol"},{"issue":"7","key":"3094_CR30","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1038\/s41591-021-01397-4","volume":"27","author":"J Singh","year":"2021","unstructured":"Singh J, Rahman SA, Ehtesham NZ, Hira S, Hasnani SE (2021) SARS-CoV-2 variants of concern are emerging in India. Nat Med 27(7):1131\u20131133. https:\/\/doi.org\/10.1038\/s41591-021-01397-4","journal-title":"Nat Med"},{"key":"3094_CR31","doi-asserted-by":"publisher","first-page":"102332","DOI":"10.1016\/j.tmaid.2022.102332","volume":"48","author":"S Das","year":"2022","unstructured":"Das S, Samanta S, Banerjee J, Pal A, Giri B, Kar SS et al (2022) Is Omicron the end of pandemic or start of a new innings? Travel Med Infect Dis 48:102332. https:\/\/doi.org\/10.1016\/j.tmaid.2022.102332","journal-title":"Travel Med Infect Dis"},{"key":"3094_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(22)00220-8","author":"WC Tan","year":"2022","unstructured":"Tan WC, Lim B-L, Young BE, Yeoh AY-Y, Yung C-F, Yap W-C et al (2022) Comparative neutralisation profile of SARS-CoV-2 omicron subvariants BA.2.75 and BA.5. Lancet Microbe. https:\/\/doi.org\/10.1016\/S2666-5247(22)00220-8","journal-title":"Lancet Microbe"},{"issue":"6","key":"3094_CR33","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/s41423-020-0400-4","volume":"17","author":"W Tai","year":"2020","unstructured":"Tai W, He L, Zhang X, Pu J, Voronin D, Jiang S et al (2020) Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine. Cell Mol Immunol 17(6):613\u2013620. https:\/\/doi.org\/10.1038\/s41423-020-0400-4","journal-title":"Cell Mol Immunol"},{"key":"3094_CR34","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.bbrc.2021.12.082","volume":"592","author":"T Koley","year":"2022","unstructured":"Koley T, Kumar M, Goswami A, Ethayathulla AS, Hariprasad G (2022) Structural modeling of Omicron spike protein and its complex with human ACE-2 receptor: molecular basis for high transmissibility of the virus. Biochem Biophys Res Commun 592:51\u201353. https:\/\/doi.org\/10.1016\/j.bbrc.2021.12.082","journal-title":"Biochem Biophys Res Commun"},{"key":"3094_CR35","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.bbrc.2022.01.006","volume":"592","author":"SL Rath","year":"2022","unstructured":"Rath SL, Padhi AK, Mandal N (2022) Scanning the RBD-ACE2 molecular interactions in Omicron variant. Biochem Biophys Res Commun 592:18\u201323. https:\/\/doi.org\/10.1016\/j.bbrc.2022.01.006","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"3094_CR36","doi-asserted-by":"publisher","first-page":"e2020216118","DOI":"10.1073\/pnas.2020216118","volume":"118","author":"K Liu","year":"2021","unstructured":"Liu K, Tan S, Niu S, Wang J, Wu L, Sun H et al (2021) Cross-species recognition of SARS-CoV-2 to bat ACE-2. Proc Natl Acad Sci U S A 118(1):e2020216118. https:\/\/doi.org\/10.1073\/pnas.2020216118","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"16","key":"3094_CR37","doi-asserted-by":"publisher","first-page":"e107786","DOI":"10.15252\/embj.2021107786","volume":"40","author":"S Niu","year":"2021","unstructured":"Niu S, Wang J, Bai B, Wu L, Zheng A, Chen Q et al (2021) Molecular basis of cross-species ACE-2 interactions with SARS-CoV-2-like viruses of pangolin origin. EMBO J 40(16):e107786. https:\/\/doi.org\/10.15252\/embj.2021107786","journal-title":"EMBO J"},{"issue":"4","key":"3094_CR38","doi-asserted-by":"publisher","first-page":"e3001237","DOI":"10.1371\/journal.pbio.3001237","volume":"19","author":"X Zhu","year":"2021","unstructured":"Zhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP (2021) Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE-2 and 2 potent neutralizing antibodies. PLoS Biol 19(4):e3001237. https:\/\/doi.org\/10.1371\/journal.pbio.3001237","journal-title":"PLoS Biol"},{"issue":"6508","key":"3094_CR39","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1126\/science.abc0870","volume":"369","author":"KK Chan","year":"2020","unstructured":"Chan KK, Dorosky D, Sharma P, Abbasi SA, Dye JM, Kranz DM et al (2020) Engineering human ACE-2 to optimize binding to the spike protein of SARS coronavirus 2. Science 369(6508):1261\u20131265. https:\/\/doi.org\/10.1126\/science.abc0870","journal-title":"Science"},{"issue":"8","key":"3094_CR40","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1038\/sj.emboj.7600640","volume":"24","author":"W Li","year":"2005","unstructured":"Li W, Zhang C, Sui J, Kuhn JH, Moore MJ, Luo S et al (2005) Receptor and viral determinants of SARS-coronavirus adaptation to human ACE-2. EMBO J 24(8):1634\u20131643. https:\/\/doi.org\/10.1038\/sj.emboj.7600640","journal-title":"EMBO J"},{"issue":"1","key":"3094_CR41","doi-asserted-by":"publisher","first-page":"14534","DOI":"10.1038\/s41598-022-18507-y","volume":"12","author":"V Durmaz","year":"2022","unstructured":"Durmaz V, Kochl K, Krassnigg A, Parigger L, Hetmann M, Singh A et al (2022) Structural bioinformatics analysis of SARS-CoV-2 variants reveals higher hACE2 receptor binding affinity for Omicron B.1.1.529 spike RBD compared to wild type reference. Sci Rep 12(1):14534. https:\/\/doi.org\/10.1038\/s41598-022-18507-y","journal-title":"Sci Rep"},{"issue":"2","key":"3094_CR42","doi-asserted-by":"publisher","first-page":"e20200104","DOI":"10.1590\/1678-4685-gmb-2020-0104","volume":"43","author":"SOF Bibiana","year":"2020","unstructured":"Bibiana SOF, Vargas-Pinilla P, Amorim CEG, Sortica VA, Bortolini MC et al (2020) ACE-2 diversity in placental mammals reveals the evolutionary strategy of SARS-CoV-2. Genet Mol Biol 43(2):e20200104. https:\/\/doi.org\/10.1590\/1678-4685-gmb-2020-0104","journal-title":"Genet Mol Biol"},{"issue":"9","key":"3094_CR43","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1002\/jmv.25832","volume":"92","author":"M Hussain","year":"2020","unstructured":"Hussain M, Jabeen N, Raza F, Shabbir S, Baig AA, Amanullah A (2020) Structural variations in human ACE-2 may influence its binding with SARS-CoV-2 spike protein. J Med Virol 92(9):1580\u20131586. https:\/\/doi.org\/10.1002\/jmv.25832","journal-title":"J Med Virol"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-03094-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-022-03094-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-03094-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T15:10:08Z","timestamp":1673363408000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-022-03094-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,22]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["3094"],"URL":"https:\/\/doi.org\/10.1007\/s00284-022-03094-y","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"value":"0343-8651","type":"print"},{"value":"1432-0991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,22]]},"assertion":[{"value":"5 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publication"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"1"}}