{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T16:49:56Z","timestamp":1771692596218,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"GSBTM","award":["GSBTM\/JD(R&D)\/610\/20\u201321\/365-371"],"award-info":[{"award-number":["GSBTM\/JD(R&D)\/610\/20\u201321\/365-371"]}]},{"name":"GSBTM","award":["GSBTM\/JD(R&D)\/616\/21\u201322\/1236"],"award-info":[{"award-number":["GSBTM\/JD(R&D)\/616\/21\u201322\/1236"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s00284-022-03108-9","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T09:07:32Z","timestamp":1671527252000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["A Comprehensive in vitro and in silico Assessment on Inhibition of CYP51B and Ergosterol Biosynthesis by Eugenol in Rhizopus oryzae"],"prefix":"10.1007","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8700-9929","authenticated-orcid":false,"given":"Jignesh","family":"Prajapati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7203-8249","authenticated-orcid":false,"given":"Priyashi","family":"Rao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6272-8732","authenticated-orcid":false,"given":"Lipi","family":"Poojara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2001-7160","authenticated-orcid":false,"given":"Dhaval","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4919-1322","authenticated-orcid":false,"given":"Saumya K.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0165-0294","authenticated-orcid":false,"given":"Dweipayan","family":"Goswami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7985-1187","authenticated-orcid":false,"given":"Rakesh M.","family":"Rawal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,20]]},"reference":[{"key":"3108_CR1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006408","author":"C Baldin","year":"2017","unstructured":"Baldin C, Ibrahim AS (2017) Molecular mechanisms of mucormycosis\u2014The bitter and the sweet. PLoS Pathog. https:\/\/doi.org\/10.1371\/journal.ppat.1006408","journal-title":"PLoS Pathog"},{"key":"3108_CR2","doi-asserted-by":"publisher","first-page":"S16","DOI":"10.1093\/cid\/cir865","volume":"54","author":"AS Ibrahim","year":"2012","unstructured":"Ibrahim AS, Spellberg B, Walsh TJ, Kontoyiannis DP (2012) Pathogenesis of mucormycosis. Clin Infect Dis 54:S16. https:\/\/doi.org\/10.1093\/cid\/cir865","journal-title":"Clin Infect Dis"},{"key":"3108_CR3","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s00284-022-02824-6","volume":"79","author":"N Ahmed","year":"2022","unstructured":"Ahmed N, Mahmood MS, Ullah MA et al (2022) COVID-19-associated Candidiasis: possible patho-mechanism, predisposing factors, and prevention strategies. Curr Microbiol 79:127. https:\/\/doi.org\/10.1007\/s00284-022-02824-6","journal-title":"Curr Microbiol"},{"key":"3108_CR4","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/s41564-020-00837-0","volume":"6","author":"SSM Soliman","year":"2021","unstructured":"Soliman SSM, Baldin C, Gu Y et al (2021) Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis. Nat Microbiol 6:313\u2013326. https:\/\/doi.org\/10.1038\/s41564-020-00837-0","journal-title":"Nat Microbiol"},{"key":"3108_CR5","doi-asserted-by":"publisher","first-page":"39611","DOI":"10.1039\/c8ra08426b","volume":"8","author":"MM Masood","year":"2018","unstructured":"Masood MM, Irfan M, Khan P et al (2018) 1,2,3-Triazole-quinazolin-4(3H)-one conjugates: evolution of ergosterol inhibitor as anticandidal agent. RSC Adv 8:39611\u201339625. https:\/\/doi.org\/10.1039\/c8ra08426b","journal-title":"RSC Adv"},{"key":"3108_CR6","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.micpath.2009.10.001","volume":"48","author":"A Ahmad","year":"2010","unstructured":"Ahmad A, Khan A, Manzoor N, Khan LA (2010) Evolution of ergosterol biosynthesis inhibitors as fungicidal against Candida. Microb Pathog 48:35\u201341. https:\/\/doi.org\/10.1016\/j.micpath.2009.10.001","journal-title":"Microb Pathog"},{"key":"3108_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fcimb.2021.660347","volume":"11","author":"G Nagy","year":"2021","unstructured":"Nagy G, Kiss S, Varghese R et al (2021) Characterization of three pleiotropic drug resistance transporter genes and their participation in the azole resistance of Mucor circinelloides. Front Cell Infect Microbiol 11:1\u201315. https:\/\/doi.org\/10.3389\/fcimb.2021.660347","journal-title":"Front Cell Infect Microbiol"},{"key":"3108_CR8","doi-asserted-by":"publisher","first-page":"104240","DOI":"10.1016\/J.BIOORG.2020.104240","volume":"104","author":"M Shafiei","year":"2020","unstructured":"Shafiei M, Peyton L, Hashemzadeh M, Foroumadi A (2020) History of the development of antifungal azoles: a review on structures, SAR, and mechanism of action. Bioorg Chem 104:104240. https:\/\/doi.org\/10.1016\/J.BIOORG.2020.104240","journal-title":"Bioorg Chem"},{"key":"3108_CR9","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1007\/S00284-020-02269-9\/TABLES\/2","volume":"78","author":"A Ganeshkumar","year":"2021","unstructured":"Ganeshkumar A, Suvaithenamudhan S, Rajaram R (2021) In vitro and in silico analysis of ascorbic acid towards lanosterol 14-\u03b1-demethylase enzyme of fluconazole-resistant Candida albicans. Curr Microbiol 78:292\u2013302. https:\/\/doi.org\/10.1007\/S00284-020-02269-9\/TABLES\/2","journal-title":"Curr Microbiol"},{"key":"3108_CR10","doi-asserted-by":"publisher","first-page":"100050","DOI":"10.1016\/j.crphar.2021.100050","volume":"2","author":"J Prajapati","year":"2021","unstructured":"Prajapati J, Goswami D, Rawal RM (2021) Endophytic fungi: a treasure trove of novel anticancer compounds. Curr Res Pharmacol Drug Discov 2:100050. https:\/\/doi.org\/10.1016\/j.crphar.2021.100050","journal-title":"Curr Res Pharmacol Drug Discov"},{"key":"3108_CR11","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/J.BIOCHI.2020.11.023","volume":"181","author":"CF Almeida","year":"2021","unstructured":"Almeida CF, Teixeira N, Oliveira A et al (2021) Discovery of a multi-target compound for estrogen receptor-positive (ER+) breast cancer: involvement of aromatase and ERs. Biochimie 181:65\u201376. https:\/\/doi.org\/10.1016\/J.BIOCHI.2020.11.023","journal-title":"Biochimie"},{"key":"3108_CR12","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/J.BIOCHI.2021.12.007","volume":"194","author":"SQ Pantale\u00e3o","year":"2022","unstructured":"Pantale\u00e3o SQ, Philot EA, de Paula H et al (2022) Virtual screening and in vitro assays of novel hits as promising DPP-4 inhibitors. Biochimie 194:43\u201350. https:\/\/doi.org\/10.1016\/J.BIOCHI.2021.12.007","journal-title":"Biochimie"},{"key":"3108_CR13","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/J.BIOCHI.2013.10.005","volume":"97","author":"P Abraham","year":"2014","unstructured":"Abraham P, George S, Kumar KS (2014) Novel antibacterial peptides from the skin secretion of the Indian bicoloured frog Clinotarsus curtipes. Biochimie 97:144\u2013151. https:\/\/doi.org\/10.1016\/J.BIOCHI.2013.10.005","journal-title":"Biochimie"},{"key":"3108_CR14","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/J.BIOCHI.2014.06.014","volume":"105","author":"H Choi","year":"2014","unstructured":"Choi H, Lee DG (2014) Antifungal activity and pore-forming mechanism of astacidin 1 against Candida albicans. Biochimie 105:58\u201363. https:\/\/doi.org\/10.1016\/J.BIOCHI.2014.06.014","journal-title":"Biochimie"},{"key":"3108_CR15","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1007\/S00284-014-0627-3\/FULLTEXT.HTML","volume":"69","author":"O Priha","year":"2014","unstructured":"Priha O, Virkaj\u00e4rvi V, Juvonen R et al (2014) Quorum sensing signalling and biofilm formation of brewery-derived bacteria, and inhibition of signalling by natural compounds. Curr Microbiol 69:617\u2013627. https:\/\/doi.org\/10.1007\/S00284-014-0627-3\/FULLTEXT.HTML","journal-title":"Curr Microbiol"},{"key":"3108_CR16","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.bbrc.2019.08.053","volume":"518","author":"SN Khan","year":"2019","unstructured":"Khan SN, Khan S, Misba L et al (2019) Synergistic fungicidal activity with low doses of eugenol and amphotericin B against Candida albicans. Biochem Biophys Res Commun 518:459\u2013464. https:\/\/doi.org\/10.1016\/j.bbrc.2019.08.053","journal-title":"Biochem Biophys Res Commun"},{"key":"3108_CR17","doi-asserted-by":"publisher","first-page":"201","DOI":"10.4274\/tjps.62207","volume":"14","author":"S Mohammadi Nejad","year":"2017","unstructured":"Mohammadi Nejad S, \u00d6zg\u00fcne\u015f H, Ba\u015faran N (2017) Pharmacological and toxicological properties of eugenol. Turkish J Pharm Sci 14:201\u2013206. https:\/\/doi.org\/10.4274\/tjps.62207","journal-title":"Turkish J Pharm Sci"},{"key":"3108_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22073671","author":"M Ulanowska","year":"2021","unstructured":"Ulanowska M, Olas B (2021) Biological properties and prospects for the application of eugenol\u2014a review. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms22073671","journal-title":"Int J Mol Sci"},{"key":"3108_CR19","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1007\/S00284-021-02344-9\/FULLTEXT.HTML","volume":"78","author":"DOS Nunes","year":"2021","unstructured":"Nunes DOS, Vinturelle R, Martins FJ et al (2021) Biotechnological potential of eugenol and thymol derivatives against Staphylococcus aureus from Bovine Mastitis. Curr Microbiol 78:1846\u20131855. https:\/\/doi.org\/10.1007\/S00284-021-02344-9\/FULLTEXT.HTML","journal-title":"Curr Microbiol"},{"key":"3108_CR20","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/J.1472-765X.2010.02867.X","volume":"51","author":"YJ Zhang","year":"2010","unstructured":"Zhang YJ, Zhang S, Liu XZ et al (2010) A simple method of genomic DNA extraction suitable for analysis of bulk fungal strains. Lett Appl Microbiol 51:114\u2013118. https:\/\/doi.org\/10.1111\/J.1472-765X.2010.02867.X","journal-title":"Lett Appl Microbiol"},{"key":"3108_CR21","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1093\/molbev\/msab120","volume":"38","author":"K Tamura","year":"2021","unstructured":"Tamura K, Stecher G, Kumar S (2021) MEGA11: molecular evolutionary genetics analysis version 11. Mol Biol Evol 38:3022\u20133027. https:\/\/doi.org\/10.1093\/molbev\/msab120","journal-title":"Mol Biol Evol"},{"key":"3108_CR22","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1016\/0045-6535(89)90512-2","volume":"19","author":"J Devillers","year":"1989","unstructured":"Devillers J, Steiman R, Seigle-Murandi F (1989) The usefulness of the agar-well diffusion method for assessing chemical toxicity to bacteria and fungi. Chemosphere 19:1693\u20131700. https:\/\/doi.org\/10.1016\/0045-6535(89)90512-2","journal-title":"Chemosphere"},{"key":"3108_CR23","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/jam.13612","volume":"124","author":"D Zhou","year":"2018","unstructured":"Zhou D, Wang Z, Li M et al (2018) Carvacrol and eugenol effectively inhibit Rhizopus stolonifer and control postharvest soft rot decay in peaches. J Appl Microbiol 124:166\u2013178. https:\/\/doi.org\/10.1111\/jam.13612","journal-title":"J Appl Microbiol"},{"key":"3108_CR24","doi-asserted-by":"publisher","first-page":"509b","DOI":"10.1039\/AN953780509B","volume":"78","author":"WHC Shaw","year":"1953","unstructured":"Shaw WHC, Jefferies JP (1953) The determination of ergosterol in yeast. Part I. the ultra-violet absorption of purified ergosterol. Analyst 78:509b\u20135514. https:\/\/doi.org\/10.1039\/AN953780509B","journal-title":"Analyst"},{"key":"3108_CR25","doi-asserted-by":"publisher","first-page":"109048","DOI":"10.1016\/j.abb.2021.109048","volume":"712","author":"J Prajapati","year":"2021","unstructured":"Prajapati J, Rao P, Poojara L et al (2021) Unravelling the antifungal mode of action of curcumin by potential inhibition of CYP51B: a computational study validated in vitro on mucormycosis agent Rhizopus oryzae. Arch Biochem Biophys 712:109048. https:\/\/doi.org\/10.1016\/j.abb.2021.109048","journal-title":"Arch Biochem Biophys"},{"key":"3108_CR26","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/s10822-013-9644-8","volume":"27","author":"GM Sastry","year":"2013","unstructured":"Sastry GM, Adzhigirey M, Sherman W (2013) Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments. J Comput Aided Mol Des 27:221\u2013234. https:\/\/doi.org\/10.1007\/s10822-013-9644-8","journal-title":"J Comput Aided Mol Des"},{"key":"3108_CR27","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1021\/jm030644s","volume":"47","author":"TA Halgren","year":"2004","unstructured":"Halgren TA, Murphy RB, Friesner RA et al (2004) Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening. J Med Chem 47:1750\u20131759. https:\/\/doi.org\/10.1021\/jm030644s","journal-title":"J Med Chem"},{"key":"3108_CR28","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-020-01997-2","author":"A Shukla","year":"2020","unstructured":"Shukla A, Parmar P, Rao P et al (2020) Twin peaks: presenting the antagonistic molecular interplay of curcumin with LasR and LuxR quorum sensing pathways. Curr Microbiol. https:\/\/doi.org\/10.1007\/s00284-020-01997-2","journal-title":"Curr Microbiol"},{"key":"3108_CR29","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1146\/annurev.biophys.30.1.211","volume":"30","author":"W Wang","year":"2001","unstructured":"Wang W, Donini O, Reyes CM, Kollman PA (2001) Biomolecular simulations: recent developments in force fields, simulations of enzyme catalysis, protein-ligand, protein-protein, and protein-nucleic acid noncovalent interactions. Annu Rev Biophys Biomol Struct 30:211\u2013243","journal-title":"Annu Rev Biophys Biomol Struct"},{"key":"3108_CR30","doi-asserted-by":"publisher","first-page":"287","DOI":"10.2174\/157340906778226454","volume":"2","author":"J Wang","year":"2006","unstructured":"Wang J, Hou T, Xu X (2006) Recent advances in free energy calculations with a combination of molecular mechanics and continuum models. Curr Comput Aided-Drug Des 2:287\u2013306. https:\/\/doi.org\/10.2174\/157340906778226454","journal-title":"Curr Comput Aided-Drug Des"},{"key":"3108_CR31","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1021\/ar000033j","volume":"33","author":"PA Kollman","year":"2000","unstructured":"Kollman PA, Massova I, Reyes C et al (2000) Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models. Acc Chem Res 33:889\u2013897. https:\/\/doi.org\/10.1021\/ar000033j","journal-title":"Acc Chem Res"},{"key":"3108_CR32","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1023\/A:1008763014207","volume":"18","author":"I Massova","year":"2000","unstructured":"Massova I, Kollman PA (2000) Combined molecular mechanical and continuum solvent approach (MM- PBSA\/GBSA) to predict ligand binding. Perspect Drug Discov Des 18:113\u2013135. https:\/\/doi.org\/10.1023\/A:1008763014207","journal-title":"Perspect Drug Discov Des"},{"key":"3108_CR33","doi-asserted-by":"crossref","unstructured":"Bowers KJ, Chow E, Xu H, et al (2006) Scalable algorithms for molecular dynamics simulations on commodity clusters. In: Proceedings of the 2006 ACM\/IEEE Conference on Supercomputing, SC\u201906. ACM Press, New York p 84","DOI":"10.1145\/1188455.1188544"},{"key":"3108_CR34","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1111\/MYC.12228","volume":"57","author":"S Dolatabadi","year":"2014","unstructured":"Dolatabadi S, de Hoog GS, Meis JF, Walther G (2014) Species boundaries and nomenclature of Rhizopus arrhizus (syn. R. oryzae). Mycoses 57:108\u2013127. https:\/\/doi.org\/10.1111\/MYC.12228","journal-title":"Mycoses"},{"key":"3108_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6882-14-309","volume":"14","author":"CMO Azeredo","year":"2014","unstructured":"Azeredo CMO, Santos TG, de Maia BHL, Soares MJ (2014) In vitro biological evaluation of eight different essential oils against Trypanosoma cruzi, with emphasis on Cinnamomum verum essential oil. BMC Complement Altern Med 14:1\u20138. https:\/\/doi.org\/10.1186\/1472-6882-14-309","journal-title":"BMC Complement Altern Med"},{"key":"3108_CR36","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.jbiosc.2016.09.011","volume":"123","author":"A Sharma","year":"2017","unstructured":"Sharma A, Rajendran S, Srivastava A et al (2017) Antifungal activities of selected essential oils against Fusarium oxysporum f. sp. lycopersici 1322, with emphasis on Syzygium aromaticum essential oil. J Biosci Bioeng 123:308\u2013313. https:\/\/doi.org\/10.1016\/j.jbiosc.2016.09.011","journal-title":"J Biosci Bioeng"},{"key":"3108_CR37","doi-asserted-by":"publisher","first-page":"507","DOI":"10.3109\/13693786.2012.742966","volume":"51","author":"PF De Oliveira","year":"2013","unstructured":"De Oliveira PF, Mendes JM, De Oliveira LE (2013) Investigation on mechanism of antifungal activity of eugenol against Trichophyton rubrum. Med Mycol 51:507\u2013513. https:\/\/doi.org\/10.3109\/13693786.2012.742966","journal-title":"Med Mycol"},{"key":"3108_CR38","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/nrd.2017.46","volume":"16","author":"JR Perfect","year":"2017","unstructured":"Perfect JR (2017) The antifungal pipeline: a reality check. Nat Rev Drug Discov 16:603\u2013616. https:\/\/doi.org\/10.1038\/nrd.2017.46","journal-title":"Nat Rev Drug Discov"},{"key":"3108_CR39","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s00253-012-4195-9","volume":"95","author":"R Becher","year":"2012","unstructured":"Becher R, Wirsel SGR (2012) Fungal cytochrome P450 sterol 14\u03b1-demethylase (CYP51) and azole resistance in plant and human pathogens. Appl Microbiol Biotechnol 95:825\u2013840. https:\/\/doi.org\/10.1007\/s00253-012-4195-9","journal-title":"Appl Microbiol Biotechnol"},{"key":"3108_CR40","doi-asserted-by":"publisher","first-page":"29015","DOI":"10.1039\/d1ra04460e","volume":"11","author":"D Goswami","year":"2021","unstructured":"Goswami D (2021) Comparative assessment of RNA-dependent RNA polymerase (RdRp) inhibitors under clinical trials to control SARS-CoV2 using rigorous computational workflow. RSC Adv 11:29015\u201329028. https:\/\/doi.org\/10.1039\/d1ra04460e","journal-title":"RSC Adv"},{"key":"3108_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-021-96963-8","volume":"11","author":"P Rao","year":"2021","unstructured":"Rao P, Goswami D, Rawal RM (2021) Revealing the molecular interplay of curcumin as Culex pipiens Acetylcholine esterase 1 (AChE1) inhibitor. Sci Rep 11:1\u201318. https:\/\/doi.org\/10.1038\/s41598-021-96963-8","journal-title":"Sci Rep"},{"key":"3108_CR42","doi-asserted-by":"publisher","first-page":"104568","DOI":"10.1016\/j.compbiomed.2021.104568","volume":"135","author":"J Prajapati","year":"2021","unstructured":"Prajapati J, Patel R, Goswami D et al (2021) Sterenin M as a potential inhibitor of SARS-CoV-2 main protease identified from MeFSAT database using molecular docking, molecular dynamics simulation and binding free energy calculation. Comput Biol Med 135:104568. https:\/\/doi.org\/10.1016\/j.compbiomed.2021.104568","journal-title":"Comput Biol Med"},{"key":"3108_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-021-01845-8","volume":"11","author":"A Shukla","year":"2021","unstructured":"Shukla A, Shukla G, Parmar P et al (2021) Exemplifying the next generation of antibiotic susceptibility intensifiers of phytochemicals by LasR-mediated quorum sensing inhibition. Sci Rep 11:1\u201323. https:\/\/doi.org\/10.1038\/s41598-021-01845-8","journal-title":"Sci Rep"},{"key":"3108_CR44","doi-asserted-by":"publisher","DOI":"10.1007\/s11030-021-10233-3","author":"P Parmar","year":"2021","unstructured":"Parmar P, Rao P, Sharma A et al (2021) Meticulous assessment of natural compounds from NPASS database for identifying analogue of GRL0617, the only known inhibitor for SARS-CoV2 papain-like protease (PLpro) using rigorous computational workflow. Mol Divers. https:\/\/doi.org\/10.1007\/s11030-021-10233-3","journal-title":"Mol Divers"},{"key":"3108_CR45","doi-asserted-by":"publisher","DOI":"10.1007\/s11030-021-10325-0","author":"R Patel","year":"2021","unstructured":"Patel R, Prajapati J, Rao P et al (2021) Repurposing the antibacterial drugs for inhibition of SARS-CoV2-PLpro using molecular docking, MD simulation and binding energy calculation. Mol Divers. https:\/\/doi.org\/10.1007\/s11030-021-10325-0","journal-title":"Mol Divers"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-03108-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-022-03108-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-022-03108-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T15:01:16Z","timestamp":1744210876000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-022-03108-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,20]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["3108"],"URL":"https:\/\/doi.org\/10.1007\/s00284-022-03108-9","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"value":"0343-8651","type":"print"},{"value":"1432-0991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,20]]},"assertion":[{"value":"2 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"47"}}