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The 16S rRNA gene sequence of strain C5-48<jats:sup>T<\/jats:sup> showed high similarity to the corresponding sequences of <jats:italic>Lachnoclostridium edouardi<\/jats:italic> Marseille-P3397<jats:sup>T<\/jats:sup> (95.7%) and <jats:italic>Clostridium fessum<\/jats:italic> SNUG30386<jats:sup>T<\/jats:sup> (94.7%). However, phylogenetic analysis using the sequences of the 16S rRNA, <jats:italic>rpoB<\/jats:italic>, and <jats:italic>hsp60<\/jats:italic> genes and whole-genome analysis strongly suggested that C5-48<jats:sup>T<\/jats:sup> should be included in the genus <jats:italic>Enterocloster<\/jats:italic>. The novelty of strain C5-48<jats:sup>T<\/jats:sup> was further confirmed by comprehensive average nucleotide identity (ANI) calculations based on its whole-genome sequence, which showed appreciable ANI values with known <jats:italic>Enterocloster<\/jats:italic> species (<jats:italic>e.g<\/jats:italic>., 74.3% and 73.4% with <jats:italic>Enterocloster bolteae<\/jats:italic> WAL 16351<jats:sup>T<\/jats:sup> and <jats:italic>Enterocloster clostridioformis<\/jats:italic> ATCC 25537<jats:sup>T<\/jats:sup>, respectively). The temperature range for growth of strain C5-48<jats:sup>T<\/jats:sup> was 15\u201337\u00a0\u00b0C with an optimum of 37\u00a0\u00b0C. The pH range for growth was 5.5\u201310.5 with an optimum of 7.5. The major constituents of the cell membrane lipids of strain C5-48<jats:sup>T<\/jats:sup> were 16:0, 14:0, and 18:1 <jats:italic>\u03c9<\/jats:italic>7<jats:italic>c<\/jats:italic> dimethyl acetal fatty acids. On the basis of the genotypic and phenotypic properties, <jats:italic>Enterocloster alcoholdehydrogenati<\/jats:italic> sp. nov. is proposed, with the type strain C5-48<jats:sup>T<\/jats:sup> (=\u2009JCM 33305<jats:sup>T<\/jats:sup>\u2009=\u2009DSM 109474<jats:sup>T<\/jats:sup>).\n<\/jats:p>","DOI":"10.1007\/s00284-023-03285-1","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T10:02:26Z","timestamp":1681898546000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Enterocloster alcoholdehydrogenati sp. nov., a Novel Bacterial Species Isolated from the Feces of a Patient with Alcoholism"],"prefix":"10.1007","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9300-4849","authenticated-orcid":false,"given":"Daiki","family":"Oikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Fukui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3280-5076","authenticated-orcid":false,"given":"Yuichi","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0128-096X","authenticated-orcid":false,"given":"Toshiyuki","family":"Waki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2288-4340","authenticated-orcid":false,"given":"Seiji","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7023-9605","authenticated-orcid":false,"given":"Takefumi","family":"Shimoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5275-4731","authenticated-orcid":false,"given":"Toru","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,19]]},"reference":[{"key":"3285_CR1","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1093\/aje\/kwn073","volume":"167","author":"T Mizoue","year":"2008","unstructured":"Mizoue T, Inoue M, Wakai K et al (2008) Alcohol drinking and colorectal cancer in Japanese: a pooled analysis of results from five cohort studies. 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