{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:10:25Z","timestamp":1759961425991,"version":"3.35.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s00284-024-04049-1","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T20:44:06Z","timestamp":1735937046000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Response Surface D-Optimal Design for Optimizing Fortimicins Production by Micromonospora olivasterospora and New Synergistic Fortimicin-A-Antibiotic Combinations"],"prefix":"10.1007","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6973-6460","authenticated-orcid":false,"given":"Heba Mohammed Refat M.","family":"Selim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7794-5890","authenticated-orcid":false,"given":"Fatma Alzahraa M.","family":"Gomaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3873-4565","authenticated-orcid":false,"given":"Mohammad Y.","family":"Alshahrani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7608-850X","authenticated-orcid":false,"given":"Khaled M.","family":"Aboshanab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,3]]},"reference":[{"key":"4049_CR1","doi-asserted-by":"publisher","first-page":"745","DOI":"10.7164\/antibiotics.42.745","volume":"42","author":"K Hotta","year":"1989","unstructured":"Hotta K, Morioka M, Okami Y (1989) Biosynthetic similarity between Streptomyces tenjimariensis and Micromonospora olivasterospora which produce fortimicin-group antibiotics. J Antibiot 42:745\u2013751. https:\/\/doi.org\/10.7164\/antibiotics.42.745","journal-title":"J Antibiot"},{"key":"4049_CR2","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/9780470149676.ch2","volume-title":"Aminoglycoside Antibiotics","author":"W Piepersberg","year":"2007","unstructured":"Piepersberg W, Aboshanab KM, Schmidt-Bei\u00dfner H, Wehmeier UF (2007) The biochemistry and genetics of aminoglycoside producers. Aminoglycoside Antibiotics. Wiley, New York, pp 15\u2013118"},{"key":"4049_CR3","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/S0076-6879(09)04619-9","volume":"459","author":"UF Wehmeier","year":"2009","unstructured":"Wehmeier UF, Piepersberg W (2009) Enzymology of aminoglycoside biosynthesis\u2014deduction from gene clusters. Methods Enzymol 459:459\u2013491","journal-title":"Methods Enzymol"},{"key":"4049_CR4","doi-asserted-by":"publisher","first-page":"564","DOI":"10.7164\/antibiotics.30.564","volume":"30","author":"RL Girolami","year":"1977","unstructured":"Girolami RL, Stamm JM (1977) Fortimicins A and B, new aminoglycoside antibiotics. IV. In vitro Study of fortimicin a compared with other aminoglycosides. J Antibiot 30:564\u2013570. https:\/\/doi.org\/10.7164\/antibiotics.30.564","journal-title":"J Antibiot"},{"key":"4049_CR5","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1128\/AAC.19.1.122","volume":"19","author":"C Thornsberry","year":"1981","unstructured":"Thornsberry C, Barry AL, Jones RN, Baker CN, Badal RE, Packer RR (1981) Antibacterial activity of fortimicin A compared with those of five other aminoglycosides, and factors affecting susceptibility tests. Antimicrob Agents Chemother 19:122\u2013129. https:\/\/doi.org\/10.1128\/AAC.19.1.122","journal-title":"Antimicrob Agents Chemother"},{"key":"4049_CR6","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1128\/AAC.16.6.823","volume":"16","author":"RN Jones","year":"1979","unstructured":"Jones RN, Barry AL, Fuchs PC, Gavan TL, Sommers HM, Gerlach EH (1979) Fortimicin A: collaborative in vitro susceptibility. Comparison with amikacin and gentamicin against 11,840 clinical bacterial isolates. Antimicrob Agents Chemother 16:823\u2013828","journal-title":"Antimicrob Agents Chemother"},{"key":"4049_CR7","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.bsheal.2023.01.001","volume":"5","author":"Y Zhang","year":"2023","unstructured":"Zhang Y, Zhang N, Wang M, Luo M, Peng Y, Li Z, Xu J, Ou M, Kan B, Li X, Lu X (2023) The prevalence and distribution of aminoglycoside resistance genes. Biosaf Health 5:14\u201320. https:\/\/doi.org\/10.1016\/j.bsheal.2023.01.001","journal-title":"Biosaf Health"},{"key":"4049_CR8","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.idc.2016.02.011","volume":"30","author":"Y Doi","year":"2016","unstructured":"Doi Y, Wachino J, Arakawa Y (2016) Aminoglycoside resistance. Infect Dis Clin North Am 30:523\u2013537. https:\/\/doi.org\/10.1016\/j.idc.2016.02.011","journal-title":"Infect Dis Clin North Am"},{"key":"4049_CR9","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1128\/jcm.18.2.440-442.1983","volume":"18","author":"AL Barry","year":"1983","unstructured":"Barry AL, Thornsberry C, Jones RN (1983) Proposed zone standards for interpretation of fortimicin A disk diffusion tests. J Clin Microbiol 18:440\u2013442. https:\/\/doi.org\/10.1128\/jcm.18.2.440-442.1983","journal-title":"J Clin Microbiol"},{"key":"4049_CR10","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1186\/s12866-024-03316-2","volume":"24","author":"NA Kamel","year":"2024","unstructured":"Kamel NA, Tohamy ST, Alshahrani MY, Aboshanab KM (2024) Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate. BMC Microbiol 24:164. https:\/\/doi.org\/10.1186\/s12866-024-03316-2","journal-title":"BMC Microbiol"},{"key":"4049_CR11","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.7164\/antibiotics.32.1061","volume":"32","author":"T Deushi","year":"1979","unstructured":"Deushi T, Iwasaki A, Kamiya K, Mizoguchi T, Nakayama M, Itoh H, Mori T (1979) New aminoglycoside antibiotics, sannamycin. J Antibiot 32:1061\u20131065. https:\/\/doi.org\/10.7164\/antibiotics.32.1061","journal-title":"J Antibiot"},{"key":"4049_CR12","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1128\/AAC.26.6.857","volume":"26","author":"N Moreau","year":"1984","unstructured":"Moreau N, Jaxel C, Le Goffic F (1984) Comparison of fortimicins with other aminoglycosides and effects on bacterial ribosome and protein synthesis. Antimicrob Agents Chemother 26:857\u2013862. https:\/\/doi.org\/10.1128\/AAC.26.6.857","journal-title":"Antimicrob Agents Chemother"},{"key":"4049_CR13","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.mycmed.2009.04.001","volume":"19","author":"D Thakur","year":"2009","unstructured":"Thakur D, Bora TC, Bordoloi GN, Mazumdar S (2009) Influence of nutrition and culturing conditions for optimum growth and antimicrobial metabolite production by Streptomyces sp. 201. J Mycol Med 19:161\u2013167. https:\/\/doi.org\/10.1016\/j.mycmed.2009.04.001","journal-title":"J Mycol Med"},{"key":"4049_CR14","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s13568-018-0536-0","volume":"8","author":"E Yang","year":"2018","unstructured":"Yang E, Fan L, Yan J, Jiang Y, Doucette C, Fillmore S, Walker B (2018) Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria. AMB Express 8:10. https:\/\/doi.org\/10.1186\/s13568-018-0536-0","journal-title":"AMB Express"},{"key":"4049_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-019-1390-1","author":"AA Ibrahim","year":"2019","unstructured":"Ibrahim AA, El-Housseiny GS, Aboshanab KM, Yassien MA, Hassouna NA (2019) Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens. BMC Microbiol. https:\/\/doi.org\/10.1186\/s12866-019-1390-1","journal-title":"BMC Microbiol"},{"key":"4049_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-021-02093-6","author":"GS El-Housseiny","year":"2021","unstructured":"El-Housseiny GS, Ibrahim AA, Yassien MA, Aboshanab KM (2021) Production and statistical optimization of Paromomycin by Streptomyces rimosus NRRL 2455 in solid state fermentation. BMC Microbiol. https:\/\/doi.org\/10.1186\/s12866-021-02093-6","journal-title":"BMC Microbiol"},{"key":"4049_CR17","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3923\/tasr.2011.121.129","volume":"6","author":"HM Ibrahim","year":"2011","unstructured":"Ibrahim HM, Elkhidir EE (2011) Response surface method as an efficient tool for medium optimisation. Trends Appl Sci Res 6:121\u2013129. https:\/\/doi.org\/10.3923\/tasr.2011.121.129","journal-title":"Trends Appl Sci Res"},{"key":"4049_CR18","doi-asserted-by":"publisher","first-page":"4737","DOI":"10.3934\/mbe.2022221","volume":"19","author":"Z Gong","year":"2022","unstructured":"Gong Z, Zhu X, Zhang C (2022) D-optimal design of the additive mixture model with multi-response. Math Biosci Eng 19:4737\u20134748. https:\/\/doi.org\/10.3934\/mbe.2022221","journal-title":"Math Biosci Eng"},{"key":"4049_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.02087","author":"V Singh","year":"2017","unstructured":"Singh V, Haque S, Niwas R, Srivastava A, Pasupuleti M, Tripathi CKM (2017) Strategies for fermentation medium optimization: an in-depth review. Front Microbiol. https:\/\/doi.org\/10.3389\/fmicb.2016.02087","journal-title":"Front Microbiol"},{"key":"4049_CR20","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1574-6968.1985.tb01001.x","volume":"30","author":"J Distler","year":"1985","unstructured":"Distler J, Klier K, Piendl W, B\u00f6ck A, Kresze G, Piepersberg W (1985) Streptomycin biosynthesis in Streptomyces griseus. I. Characterization of streptomycin-idiotrophic mutants. FEMS Microbiol Lett 30:145\u2013150","journal-title":"FEMS Microbiol Lett"},{"key":"4049_CR21","volume-title":"Practical Streptomyces genetics","author":"T Kieser","year":"2000","unstructured":"Kieser T, Bibb M, Buttner M, Chater K, Hopwood D (2000) Practical Streptomyces genetics. John Innes Foundation, Norwich"},{"key":"4049_CR22","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.jpha.2015.11.005","volume":"6","author":"M Balouiri","year":"2016","unstructured":"Balouiri M, Sadiki M, Ibnsouda SK (2016) Methods for in vitro evaluating antimicrobial activity: a review. J Pharm Anal 6:71\u201379. https:\/\/doi.org\/10.1016\/j.jpha.2015.11.005","journal-title":"J Pharm Anal"},{"key":"4049_CR23","unstructured":"Miller JH (1972) Experiments in molecular genetics. Cold Spring Harbor Laboratory, USA, pp 1-466"},{"key":"4049_CR24","unstructured":"Holt JG, Krieg NR, Sneath PH, Staley JT, Williams ST (1994): Bergey's Manual of determinate bacteriology. (https:\/\/www.scirp.org\/(S(i43dyn45teexjx455qlt3d2q))\/reference\/ReferencesPapersaspx?ReferenceID=42336; accessed on 12 June 2024)"},{"key":"4049_CR25","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1136\/jcp.51.4.316","volume":"51","author":"N Shetty","year":"1998","unstructured":"Shetty N, Hill G, Ridgway G (1998) The Vitek analyser for routine bacterial identification and susceptibility testing: protocols, problems, and pitfalls. J Clin Pathol 51:316\u2013323. https:\/\/doi.org\/10.1136\/jcp.51.4.316","journal-title":"J Clin Pathol"},{"key":"4049_CR26","unstructured":"CLSI: Performance standards for antimicrobial susceptibility testing. Clinical and Laboratory Standards Institute 2022. In., vol. M100-Ed31 https:\/\/clsi.org\/standards\/products\/microbiology\/documents\/m100\/ (accessed on 12 June 2024)."},{"key":"4049_CR27","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","volume":"18","author":"A-P Magiorakos","year":"2012","unstructured":"Magiorakos A-P, Srinivasan A, Carey RB, Carmeli Y, Falagas M, Giske C et al (2012) Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 18:268\u2013281. https:\/\/doi.org\/10.1111\/j.1469-0691.2011.03570.x","journal-title":"Clin Microbiol Infect"},{"key":"4049_CR28","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/0732-8893(93)90087-n","volume":"16","author":"MH Hsieh","year":"1993","unstructured":"Hsieh MH, Chen MY, Victor LY, Chow JW (1993) Synergy assessed by checkerboard a critical analysis. Diagn Microbiol Infect Dis 16:343\u2013349. https:\/\/doi.org\/10.1016\/0732-8893(93)90087-n","journal-title":"Diagn Microbiol Infect Dis"},{"key":"4049_CR29","doi-asserted-by":"publisher","first-page":"1719","DOI":"10.1099\/jmm.0.047100-0","volume":"61","author":"IS Hwang","year":"2012","unstructured":"Hwang IS, Hwang JH, Choi H, Kim KJ, Lee DG (2012) Synergistic effects between silver nanoparticles and antibiotics and the mechanisms involved. J Med Microbiol 61:1719\u20131726. https:\/\/doi.org\/10.1099\/jmm.0.047100-0","journal-title":"J Med Microbiol"},{"key":"4049_CR30","first-page":"75","volume":"47","author":"VG Chalenko","year":"1970","unstructured":"Chalenko VG, Volodina IK, Rumiantsev SN (1970) Colorimetric dry weight of bacterial cultures. I. Details of the method. Zh Mikrobiol Epidemiol Immunobiol 47:75\u201381","journal-title":"Zh Mikrobiol Epidemiol Immunobiol"},{"key":"4049_CR31","doi-asserted-by":"publisher","first-page":"2802","DOI":"10.1128\/jb.170.6.2802-2808.1988","volume":"170","author":"MJ Babcock","year":"1988","unstructured":"Babcock MJ, Kendrick KE (1988) Cloning of DNA involved in sporulation of Streptomyces griseus. J Bacteriol 170:2802\u20132808. https:\/\/doi.org\/10.1128\/jb.170.6.2802-2808.1988","journal-title":"J Bacteriol"},{"key":"4049_CR32","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1128\/AAC.27.5.798","volume":"27","author":"DH Nam","year":"1985","unstructured":"Nam DH, Ryu DD (1985) Relationship between butirosin biosynthesis and sporulation in Bacillus circulans. Antimicrob Agents Chemother 27:798\u2013801. https:\/\/doi.org\/10.1128\/AAC.27.5.798","journal-title":"Antimicrob Agents Chemother"},{"key":"4049_CR33","volume-title":"Response surface methodology in engineering science","author":"S Bhattacharya","year":"2021","unstructured":"Bhattacharya S (2021) Central composite design for response surface methodology and its application in pharmacy. Response surface methodology in engineering science. IntechOpen"},{"key":"4049_CR34","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1080\/1028415X.1999.11747262","volume":"2","author":"HW Thompson","year":"1999","unstructured":"Thompson HW, Mera R, Prasad C (1999) The analysis of variance (ANOVA). Nutr Neurosci 2:43\u201355. https:\/\/doi.org\/10.1080\/1028415X.1999.11747262","journal-title":"Nutr Neurosci"},{"key":"4049_CR35","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/S0021-9673(00)81948-2","volume":"208","author":"JL Elrod","year":"1981","unstructured":"Elrod JL, White LB, Wong CF (1981) Determination of fortimicin a sulfate by high-performance liquid chromatography after derivatization with 2,4-dinitrofluorobenzene. J Chromatogr A 208:357\u2013363. https:\/\/doi.org\/10.1016\/S0021-9673(00)81948-2","journal-title":"J Chromatogr A"},{"key":"4049_CR36","doi-asserted-by":"publisher","DOI":"10.18683\/germs.2022.1308","author":"SH Mostafa","year":"2022","unstructured":"Mostafa SH, Saleh SE, Hamed SM, Aboshanab KM (2022) Febrile illness of bacterial etiology in a public fever hospital in Egypt: high burden of multidrug resistance and WHO priority Gram negative pathogens. Germs. https:\/\/doi.org\/10.18683\/germs.2022.1308","journal-title":"Germs"},{"key":"4049_CR37","doi-asserted-by":"publisher","first-page":"860","DOI":"10.3390\/antibiotics12050860","volume":"12","author":"M Thy","year":"2023","unstructured":"Thy M, Timsit J-F, de Montmollin E (2023) Aminoglycosides for the treatment of severe infection due to resistant gram-negative pathogens. Antibiotics 12:860. https:\/\/doi.org\/10.3390\/antibiotics12050860","journal-title":"Antibiotics"},{"key":"4049_CR38","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1007\/s11274-022-03445-8","volume":"39","author":"CM Webster","year":"2023","unstructured":"Webster CM, Shepherd M (2023) A mini-review: environmental and metabolic factors affecting aminoglycoside efficacy. World J Microbiol Biotechnol 39:7. https:\/\/doi.org\/10.1007\/s11274-022-03445-8","journal-title":"World J Microbiol Biotechnol"},{"issue":"10","key":"4049_CR39","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1007\/s11274-024-04118-4","volume":"40","author":"FAM Gomaa","year":"2024","unstructured":"Gomaa FAM, Selim HMRM, Alshahrani MY, Aboshanab KM (2024) Central composite design for optimizing istamycin production by Streptomyces tenjimariensis. World J Microbiol Biotechnol 40(10):316. https:\/\/doi.org\/10.1007\/s11274-024-04118-4","journal-title":"World J Microbiol Biotechnol"},{"key":"4049_CR40","doi-asserted-by":"publisher","first-page":"17","DOI":"10.7164\/antibiotics.30.17","volume":"30","author":"T Nara","year":"1977","unstructured":"Nara T, Yamamoto M, Takasawa S, Sato S, Sato T, Kawamoto I, Okachi R, Takahashi I, Morikawa A (1977) A new aminoglycoside antibiotic complex\u2014the seldomycins. I. Taxonomy, fermentation and antibacterial properties. J Antibiot 30:17\u201324. https:\/\/doi.org\/10.7164\/antibiotics.30.17","journal-title":"J Antibiot"},{"key":"4049_CR41","doi-asserted-by":"publisher","first-page":"4259","DOI":"10.1007\/s00253-017-8189-5","volume":"101","author":"K Kasuga","year":"2017","unstructured":"Kasuga K, Sasaki A, Matsuo T, Yamamoto C, Minato Y, Kuwahara N, Fujii C, Kobayashi M, Agematu H, Tamura T, Komatsu M, Ishikawa J, Ikeda H, Kojima I (2017) Heterologous production of kasugamycin, an aminoglycoside antibiotic from Streptomyces kasugaensis, in Streptomyces lividans and Rhodococcus erythropolis L-88 by constitutive expression of the biosynthetic gene cluster. Appl Microbiol Biotechnol 101:4259\u20134268. https:\/\/doi.org\/10.1007\/s00253-017-8189-5","journal-title":"Appl Microbiol Biotechnol"},{"key":"4049_CR42","unstructured":"Yoshihiko Oka K, Hitoshi Ishida A, Moto Morioka N, Yoso Numusaki A, Tsutomu Yamafuji T, Takashi Osono (1981) Process for production of aminoglycoside antibiotics. USA patent. US4279997A. https:\/\/patents.google.com\/patent\/US4279997A\/en"},{"key":"4049_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-020-10962-9","author":"SE El-Sayed","year":"2020","unstructured":"El-Sayed SE, Abdelaziz NA, El-Housseiny GS, Aboshanab KM (2020) Octadecyl 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) propanoate, an antifungal metabolite of Alcaligenes faecalis strain MT332429 optimized through response surface methodology. Appl Microbiol Biotechnol. https:\/\/doi.org\/10.1007\/s00253-020-10962-9","journal-title":"Appl Microbiol Biotechnol"},{"key":"4049_CR44","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1080\/00224065.2020.1757391","volume":"53","author":"B Jones","year":"2021","unstructured":"Jones B, Allen-Moyer K, Goos P (2021) A-optimal versus D-optimal design of screening experiments. J Qual Technol 53:369\u2013382. https:\/\/doi.org\/10.1080\/00224065.2020.1757391","journal-title":"J Qual Technol"},{"key":"4049_CR45","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1049\/iet-syb:20080094","volume":"3","author":"R Schenkendorf","year":"2009","unstructured":"Schenkendorf R, Kremling A, Mangold M (2009) Optimal experimental design with the sigma point method. IET Syst Biol 3:10\u201323. https:\/\/doi.org\/10.1049\/iet-syb:20080094","journal-title":"IET Syst Biol"},{"key":"4049_CR46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4103\/jpbs.jpbs_372_23","volume":"16","author":"IPW Sanjaya","year":"2024","unstructured":"Sanjaya IPW, Sudarsono, Chan MT, Sukma D, Buchori A, Putra RP, Nurcholis W (2024) D-optimal design optimization of solvent mixture for flavonoid extraction from\u00a0Phalaenopsis\u00a0leaves with antioxidant activity. J Pharm Bioallied Sci 16:1\u20137. https:\/\/doi.org\/10.4103\/jpbs.jpbs_372_23","journal-title":"J Pharm Bioallied Sci"},{"issue":"7","key":"4049_CR47","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.3390\/molecules29071614","volume":"29","author":"Y Elmahboub","year":"2024","unstructured":"Elmahboub Y, Albash R, Magdy William M, Rayan AH, Hamed NO, Ousman MS, Raslan NA, Mosallam S (2024) Metformin loaded zein polymeric nanoparticles to augment antitumor activity against ehrlich carcinoma via activation of AMPK pathway: D-optimal design optimization, in vitro characterization, and in vivo study. Molecules 29(7):1614. https:\/\/doi.org\/10.3390\/molecules29071614","journal-title":"Molecules"},{"key":"4049_CR48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10826068.2023.2297709","volume":"3","author":"A Mokhtari","year":"2024","unstructured":"Mokhtari A, Omidi M, Ebrahimi M, Alizadeh H, Sobhani A, Azadi P, Noormohammadi N, Shafaie M (2024) Optimizing the extract yield of bioactive compounds in\u00a0Valeriana officinalis\u00a0root: a D-optimal design. Prep Biochem Biotechnol 3:1\u201311. https:\/\/doi.org\/10.1080\/10826068.2023.2297709","journal-title":"Prep Biochem Biotechnol"},{"key":"4049_CR49","doi-asserted-by":"publisher","first-page":"130948","DOI":"10.1016\/j.ijbiomac.2024.130948","volume":"265","author":"S Hamid","year":"2024","unstructured":"Hamid S, Oukil NF, Moussa H, Mahdjoub MM, Djihad N, Berrabah I, Bouhenna MM, Chebrouk F, Hentabli M (2024) Enhancing basil essential oil microencapsulation using pectin\/casein biopolymers: optimization through D-optimal design, controlled release modeling, and characterization. Int J Biol Macromol 265:130948. https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.130948","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"4049_CR50","doi-asserted-by":"publisher","first-page":"2343","DOI":"10.1080\/10717544.2022.2100513","volume":"29","author":"AA Nemr","year":"2022","unstructured":"Nemr AA, El-Mahrouk GM, Badie HA (2022) Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation,\u00a0in vitro\u00a0characterization, and\u00a0in vivo\u00a0pharmacodynamic evaluation in rabbits. Drug Deliv 29(1):2343\u20132356. https:\/\/doi.org\/10.1080\/10717544.2022.2100513","journal-title":"Drug Deliv"},{"key":"4049_CR51","doi-asserted-by":"publisher","first-page":"112262","DOI":"10.1016\/j.msec.2021.112262","volume":"128","author":"M Zohri","year":"2021","unstructured":"Zohri M, Arefian E, Akbari Javar H, Gazori T, Aghaee-Bakhtiari SH, Taheri M, Fatahi Y, Azadi A, Khoshayand MR, Ghahremani MH (2021) Potential of chitosan\/alginate nanoparticles as a non-viral vector for gene delivery: Formulation and optimization using D-optimal design. Mater Sci Eng C Mater Biol Appl 128:112262. https:\/\/doi.org\/10.1016\/j.msec.2021.112262","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"issue":"3","key":"4049_CR52","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3390\/molecules22030457","volume":"22","author":"T Liang","year":"2017","unstructured":"Liang T, Guan R, Shen H, Xia Q, Liu M (2017) Optimization of conditions for Cyanidin-3-OGlucoside (C3G) nanoliposome production by response surface methodology and cellular uptake studies in Caco-2 cells. Molecules 22(3):457. https:\/\/doi.org\/10.3390\/molecules22030457","journal-title":"Molecules"},{"key":"4049_CR53","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/s12866-014-0278-3","volume":"14","author":"LS Singh","year":"2014","unstructured":"Singh LS, Sharma H, Talukdar NC (2014) Production of potent antimicrobial agent by actinomycete, Streptomyces sannanensis strain SU118 isolated from phoomdi in Loktak Lake of Manipur India. BMC Microbiol 14:278. https:\/\/doi.org\/10.1186\/s12866-014-0278-3","journal-title":"BMC Microbiol"},{"key":"4049_CR54","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-011-9079-2","author":"F Khoshayand","year":"2011","unstructured":"Khoshayand F, Goodarzi S, Shahverdi AR, Khoshayand MR (2011) Optimization of culture conditions for fermentation of soymilk using Lactobacillus casei by response surface methodology. Probiotics Antimicrob Proteins. https:\/\/doi.org\/10.1007\/s12602-011-9079-2","journal-title":"Probiotics Antimicrob Proteins"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-024-04049-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-024-04049-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-024-04049-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T04:21:52Z","timestamp":1738210912000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-024-04049-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,3]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["4049"],"URL":"https:\/\/doi.org\/10.1007\/s00284-024-04049-1","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"type":"print","value":"0343-8651"},{"type":"electronic","value":"1432-0991"}],"subject":[],"published":{"date-parts":[[2025,1,3]]},"assertion":[{"value":"5 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there are no conflict of interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"68"}}