{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:22:17Z","timestamp":1757618537410,"version":"3.44.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s00284-025-04316-9","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T21:44:16Z","timestamp":1750196656000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the Efficacy of Amoxicillin-Broccoli Combination in Combating Multidrug-Resistant Staphylococcus aureus Infection"],"prefix":"10.1007","volume":"82","author":[{"given":"Habiba","family":"Mosaad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8287-1026","authenticated-orcid":false,"given":"Engy","family":"Elekhnawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walaa A.","family":"Negm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salwa S.","family":"Younis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"El-Aasr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"issue":"1","key":"4316_CR1","doi-asserted-by":"publisher","first-page":"1848","DOI":"10.1080\/10717544.2022.2083725","volume":"29","author":"B Alotaibi","year":"2022","unstructured":"Alotaibi B et al (2022) Aqueous core epigallocatechin gallate PLGA nanocapsules: characterization, antibacterial activity against uropathogens, and in vivo reno-protective effect in cisplatin induced nephrotoxicity. Drug Deliv 29(1):1848\u20131862","journal-title":"Drug Deliv"},{"issue":"8","key":"4316_CR2","doi-asserted-by":"publisher","first-page":"993","DOI":"10.3390\/antibiotics11080993","volume":"11","author":"NG Attallah","year":"2022","unstructured":"Attallah NG et al (2022) Anti-Biofilm and Antibacterial Activities of Cycas media R. Br Secondary Metabolites: In Silico, In Vitro, and In Vivo Approaches. Antibiotics 11(8):993","journal-title":"Antibiotics"},{"issue":"10","key":"4316_CR3","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.3390\/jof8101005","volume":"8","author":"FA Alherz","year":"2022","unstructured":"Alherz FA et al (2022) Silver nanoparticles prepared using encephalartos laurentianus de wild leaf extract have inhibitory activity against candida albicans clinical isolates. J Fungi 8(10):1005","journal-title":"J Fungi"},{"key":"4316_CR4","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3389\/fcimb.2020.00107","volume":"10","author":"Y Guo","year":"2020","unstructured":"Guo Y et al (2020) Prevalence and therapies of antibiotic-resistance in Staphylococcus aureus. Front Cell Infect Microbiol 10:107","journal-title":"Front Cell Infect Microbiol"},{"issue":"8","key":"4316_CR5","doi-asserted-by":"publisher","first-page":"946","DOI":"10.3390\/plants9080946","volume":"9","author":"TN Le","year":"2020","unstructured":"Le TN, Chiu C-H, Hsieh P-C (2020) Bioactive compounds and bioactivities of Brassica oleracea L. var. italica sprouts and microgreens: An updated overview from a nutraceutical perspective. Plants 9(8):946","journal-title":"Plants"},{"issue":"3","key":"4316_CR6","doi-asserted-by":"publisher","first-page":"182","DOI":"10.15326\/jcopdf.7.3.2019.0152","volume":"7","author":"S Janciauskiene","year":"2020","unstructured":"Janciauskiene S (2020) The beneficial effects of antioxidants in health and diseases. Chronic Obstructive Pulmonary Diseases: J COPD Found 7(3):182","journal-title":"Chronic Obstructive Pulmonary Diseases: J COPD Found"},{"issue":"3","key":"4316_CR7","doi-asserted-by":"publisher","first-page":"602","DOI":"10.3390\/antiox11030602","volume":"11","author":"S Suriyaprom","year":"2022","unstructured":"Suriyaprom S et al (2022) Antioxidants of fruit extracts as antimicrobial agents against pathogenic bacteria. Antioxid 11(3):602","journal-title":"Antioxid"},{"issue":"3","key":"4316_CR8","first-page":"352","volume":"14","author":"L He","year":"2024","unstructured":"He L et al (2024) Sulforaphane-enriched extracts from broccoli exhibit antimicrobial activity against plant pathogens. Promis Nat Antimicrob Ag Crop Prot 14(3):352","journal-title":"Promis Nat Antimicrob Ag Crop Prot"},{"issue":"22","key":"4316_CR9","doi-asserted-by":"publisher","first-page":"7841","DOI":"10.3390\/molecules27227841","volume":"27","author":"FM Abdel Bar","year":"2022","unstructured":"Abdel Bar FM et al (2022) Anti-quorum sensing and anti-biofilm activity of Pelargonium\u00d7 hortorum root extract against Pseudomonas aeruginosa: combinatorial effect of catechin and gallic acid. Mol 27(22):7841","journal-title":"Mol"},{"key":"4316_CR10","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.3389\/fmicb.2019.01638","volume":"10","author":"Q Yao","year":"2019","unstructured":"Yao Q et al (2019) Amoxicillin administration regimen and resistance mechanisms of Staphylococcus aureus established in tissue cage infection model. Front Microbiol 10:1638","journal-title":"Front Microbiol"},{"issue":"17","key":"4316_CR11","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.3390\/plants12173077","volume":"12","author":"EM Abdallah","year":"2023","unstructured":"Abdallah EM et al (2023) Back to Nature: Medicinal plants as promising sources for antibacterial drugs in the post-antibiotic era. Plants 12(17):3077","journal-title":"Plants"},{"key":"4316_CR12","doi-asserted-by":"publisher","first-page":"128075","DOI":"10.1016\/j.foodchem.2020.128075","volume":"339","author":"M Rad\u00fcnz","year":"2021","unstructured":"Rad\u00fcnz M et al (2021) Encapsulation of broccoli extract by electrospraying: influence of in vitro simulated digestion on phenolic and glucosinolate contents, and on antioxidant and antihyperglycemic activities. F chem 339:128075","journal-title":"F chem"},{"issue":"5","key":"4316_CR13","first-page":"343","volume":"8","author":"WA Negm","year":"2016","unstructured":"Negm WA, Abd El-Rahim SI, El-Seoud KA, Attia GI, Ragab AE (2016) A new cytotoxic and antioxidant Amentoflavone Monoglucoside from Cycas revoluta Thunb growing in Egypt. J Pharm Sci Res 8(5):343","journal-title":"J Pharm Sci Res"},{"issue":"23","key":"4316_CR14","doi-asserted-by":"publisher","first-page":"5166","DOI":"10.1080\/14786419.2020.1789636","volume":"35","author":"WA Negm","year":"2021","unstructured":"Negm WA, Abo El-Seoud KA, Kabbash A, Kassab AA, El-Aasr M (2021) Hepatoprotective, cytotoxic, antimicrobial and antioxidant activities of Dioon spinulosum leaves Dyer Ex Eichler and its isolated secondary metabolites. Nat Prod Res 35(23):5166\u20135176","journal-title":"Nat Prod Res"},{"issue":"5","key":"4316_CR15","doi-asserted-by":"publisher","first-page":"693","DOI":"10.3390\/life12050693","volume":"12","author":"EM Seliem","year":"2022","unstructured":"Seliem EM et al (2022) Green coffee bean extract normalize obesity-induced alterations of metabolic parameters in rats by upregulating adiponectin and GLUT4 levels and reducing RBP-4 and HOMA-IR. Life 12(5):693","journal-title":"Life"},{"issue":"2","key":"4316_CR16","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.jpha.2015.11.005","volume":"6","author":"M Balouiri","year":"2016","unstructured":"Balouiri M, Sadiki M, Ibnsouda SK (2016) Methods for in vitro evaluating antimicrobial activity: A review. J pharm anal 6(2):71\u201379","journal-title":"J pharm anal"},{"key":"4316_CR17","doi-asserted-by":"publisher","first-page":"232","DOI":"10.3389\/fmicb.2020.00232","volume":"11","author":"ID Nix","year":"2020","unstructured":"Nix ID et al (2020) Detection of methicillin resistance in Staphylococcus aureus from agar cultures and directly from positive blood cultures using MALDI-TOF mass spectrometry-based direct-on-target microdroplet growth assay. Front Microbiol 11:232","journal-title":"Front Microbiol"},{"issue":"1","key":"4316_CR18","doi-asserted-by":"publisher","first-page":"48","DOI":"10.21608\/zjps.2017.38130","volume":"26","author":"S El-Adl","year":"2017","unstructured":"El-Adl S et al (2017) Evaluation of the potency of some antibiotic formulations in the Egyptian market. Zagazig J Pharm Sci 26(1):48\u201354","journal-title":"Zagazig J Pharm Sci"},{"issue":"1","key":"4316_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12866-024-03214-7","volume":"24","author":"MS Abdel-Halim","year":"2024","unstructured":"Abdel-Halim MS et al (2024) Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae. BMC Microbiol 24(1):1\u201312","journal-title":"BMC Microbiol"},{"issue":"9","key":"4316_CR20","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1128\/AAC.42.9.2375","volume":"42","author":"D Andes","year":"1998","unstructured":"Andes D, Craig W (1998) In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob Agents Chemother 42(9):2375\u20132379","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"4316_CR21","doi-asserted-by":"publisher","first-page":"450","DOI":"10.3390\/antibiotics13050450","volume":"13","author":"J Alqahtani","year":"2024","unstructured":"Alqahtani J et al (2024) Potential surviving effect of cleome droserifolia extract against systemic staphylococcus aureus infection: investigation of the chemical content of the plant. Antibiot 13(5):450","journal-title":"Antibiot"},{"issue":"9","key":"4316_CR22","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1128\/AAC.42.9.2375","volume":"42","author":"D Andes","year":"1998","unstructured":"Andes D, Craig W (1998) In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob ag chemother 42(9):2375\u20132379","journal-title":"Antimicrob ag chemother"},{"issue":"11","key":"4316_CR23","first-page":"1361","volume":"15","author":"HM Al-Kuraishy","year":"2022","unstructured":"Al-Kuraishy HM et al (2022) Potential therapeutic benefits of metformin alone and in combination with sitagliptin in the management of type 2 diabetes patients with COVID-19. Pharm 15(11):1361","journal-title":"Pharm"},{"key":"4316_CR24","doi-asserted-by":"publisher","first-page":"113673","DOI":"10.1016\/j.biopha.2022.113673","volume":"154","author":"HM Al-Kuraishy","year":"2022","unstructured":"Al-Kuraishy HM et al (2022) Investigation of the impact of rosuvastatin and telmisartan in doxorubicin-induced acute cardiotoxicity. Biomed Pharmacother 154:113673","journal-title":"Biomed Pharmacother"},{"key":"4316_CR25","doi-asserted-by":"publisher","unstructured":"Vestergaard, M., D. Frees, and H. Ingmer, Antibiotic resistance and the MRSA problem. Microbiology spectrum, 2019. 7(2): p. https:\/\/doi.org\/10.1128\/microbiolspec. gpp3\u20130057\u20132018.","DOI":"10.1128\/microbiolspec"},{"key":"4316_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13756-017-0243-7","volume":"6","author":"S Deyno","year":"2017","unstructured":"Deyno S, Fekadu S, Astatkie A (2017) Resistance of Staphylococcus aureus to antimicrobial agents in Ethiopia: a meta-analysis. Antimicrob Resist Infect Control 6:1\u201315","journal-title":"Antimicrob Resist Infect Control"},{"issue":"4","key":"4316_CR27","doi-asserted-by":"publisher","first-page":"103604","DOI":"10.1016\/j.sjbs.2023.103604","volume":"30","author":"BA Alghamdi","year":"2023","unstructured":"Alghamdi BA et al (2023) Antimicrobial resistance in methicillin-resistant Staphylococcus aureus. Saudi j biological sci 30(4):103604","journal-title":"Saudi j biological sci"},{"key":"4316_CR28","doi-asserted-by":"crossref","unstructured":"Gurung, R.R., P. Maharjan, and G.G. Chhetri 2020, Antibiotic resistance pattern of Staphylococcus aureus with reference to MRSA isolates from pediatric patients. Future science OA,. 6(4): p. FSO464.","DOI":"10.2144\/fsoa-2019-0122"},{"key":"4316_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40360-017-0141-x","volume":"18","author":"S Deyno","year":"2017","unstructured":"Deyno S et al (2017) Antimicrobial resistance profile of staphylococcus aureus isolates isolated from ear discharges of patients at University of Hawassa comprehensive specialized hospital. BMC Pharmacol Toxicol 18:1\u20137","journal-title":"BMC Pharmacol Toxicol"},{"issue":"3","key":"4316_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2023.103576","volume":"30","author":"S Atta","year":"2023","unstructured":"Atta S et al (2023) Antibacterial potential and synergistic interaction between natural polyphenolic extracts and synthetic antibiotic on clinical isolates. Saudi Journal of Biological Sciences 30(3):103576","journal-title":"Saudi Journal of Biological Sciences"},{"issue":"13","key":"4316_CR31","first-page":"1147","volume":"3","author":"O Aiyegoro","year":"2009","unstructured":"Aiyegoro O, Okoh A (2009) Use of bioactive plant products in combination with standard antibiotics: Implications in antimicrobial chemotherapy. Journal of Medicinal Plants Research 3(13):1147\u20131152","journal-title":"Journal of Medicinal Plants Research"},{"issue":"14","key":"4316_CR32","doi-asserted-by":"publisher","first-page":"74","DOI":"10.14715\/cmb\/2016.62.14.13","volume":"62","author":"K Akilandeswari","year":"2016","unstructured":"Akilandeswari K, Ruckmani K (2016) Synergistic antibacterial effect of apigenin with \u00ce2-lactam antibiotics and modulation of bacterial resistance by a possible membrane effect against methicillin resistant Staphylococcus aureus. Cell Mol Biol (Noisy-le-grand) 62(14):74\u201382","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"key":"4316_CR33","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.indcrop.2017.09.028","volume":"109","author":"LA Dra","year":"2017","unstructured":"Dra LA et al (2017) Chemical composition, antioxidant and evidence antimicrobial synergistic effects of Periploca laevigata essential oil with conventional antibiotics. Ind Crops Prod 109:746\u2013752","journal-title":"Ind Crops Prod"},{"issue":"22","key":"4316_CR34","doi-asserted-by":"publisher","first-page":"7481","DOI":"10.3390\/molecules28227481","volume":"28","author":"K Prasad","year":"2023","unstructured":"Prasad K et al (2023) Enhanced Antimicrobial Activity through Synergistic Effects of Cold Atmospheric Plasma and Plant Secondary Metabolites: Opportunities and Challenges. Molecules 28(22):7481","journal-title":"Molecules"},{"issue":"5","key":"4316_CR35","doi-asserted-by":"publisher","first-page":"549","DOI":"10.3390\/ph15050549","volume":"15","author":"NG Attallah","year":"2022","unstructured":"Attallah NG et al (2022) Mechanistic insights on the in vitro antibacterial activity and in vivo hepatoprotective effects of salvinia auriculata aubl against methotrexate-induced liver injury. Pharmaceuticals 15(5):549","journal-title":"Pharmaceuticals"},{"issue":"11","key":"4316_CR36","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.3390\/ph16111615","volume":"16","author":"G Muteeb","year":"2023","unstructured":"Muteeb G et al (2023) Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review. Pharmaceuticals 16(11):1615","journal-title":"Pharmaceuticals"},{"key":"4316_CR37","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.610070","volume":"11","author":"T Su","year":"2020","unstructured":"Su T et al (2020) Novel opportunity to reverse antibiotic resistance: To explore traditional Chinese medicine with potential activity against antibiotics-resistance bacteria. Front Microbiol 11:610070","journal-title":"Front Microbiol"},{"key":"4316_CR38","doi-asserted-by":"publisher","first-page":"1188752","DOI":"10.3389\/fvets.2023.1188752","volume":"10","author":"AM Almuzaini","year":"2023","unstructured":"Almuzaini AM (2023) Phytochemicals: Potential alternative strategy to fight Salmonella enterica serovar typhimurium. Frontiers in Veterinary Science 10:1188752","journal-title":"Frontiers in Veterinary Science"},{"key":"4316_CR39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12941-021-00485-0","volume":"20","author":"MK Dassanayake","year":"2021","unstructured":"Dassanayake MK, Khoo T-J, An J (2021) Antibiotic resistance modifying ability of phytoextracts in anthrax biological agent Bacillus anthracis and emerging superbugs: a review of synergistic mechanisms. Ann Clin Microbiol Antimicrob 20:1\u201336","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"22","key":"4316_CR40","doi-asserted-by":"publisher","first-page":"57","DOI":"10.4103\/phrev.phrev_21_17","volume":"11","author":"MJ Cheesman","year":"2017","unstructured":"Cheesman MJ et al (2017) Developing new antimicrobial therapies: are synergistic combinations of plant extracts\/compounds with conventional antibiotics the solution? Pharmacogn Rev 11(22):57","journal-title":"Pharmacogn Rev"},{"key":"4316_CR41","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.cbi.2019.05.050","volume":"308","author":"M Ayaz","year":"2019","unstructured":"Ayaz M et al (2019) Synergistic interactions of phytochemicals with antimicrobial agents: Potential strategy to counteract drug resistance. Chem Biol Interact 308:294\u2013303","journal-title":"Chem Biol Interact"},{"issue":"23","key":"4316_CR42","doi-asserted-by":"publisher","first-page":"3918","DOI":"10.3390\/foods13233918","volume":"13","author":"I Gudi\u00f1o","year":"2024","unstructured":"Gudi\u00f1o I et al (2024) Comprehensive analysis of bioactive compounds, functional properties, and applications of broccoli by-products. Foods 13(23):3918","journal-title":"Foods"},{"issue":"1","key":"4316_CR43","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1080\/21691401.2023.2207606","volume":"51","author":"A Saleh","year":"2023","unstructured":"Saleh A, Abdelkader DH, El-Masry TA, Eliwa D, Alotaibi B, Negm WA, Elekhnawy E (2023) Antiviral and antibacterial potential of electrosprayed PVA\/PLGA nanoparticles loaded with chlorogenic acid for the management of coronavirus and Pseudomonas aeruginosa lung infection. Artif Cells, Nanomedicine, and Biotechnol 51(1):255\u2013267","journal-title":"Artif Cells, Nanomedicine, and Biotechnol"},{"key":"4316_CR44","volume":"462","author":"Y Liu","year":"2025","unstructured":"Liu Y et al (2025) Investigating the synergistic antibacterial effects of chlorogenic and p-coumaric acids on Shigella dysenteriae 462:141011","journal-title":"Investigating the synergistic antibacterial effects of chlorogenic and p-coumaric acids on Shigella dysenteriae"},{"issue":"17","key":"4316_CR45","doi-asserted-by":"publisher","first-page":"2544","DOI":"10.2174\/1389557521666210105123834","volume":"21","author":"R Choi\u0144ska","year":"2021","unstructured":"Choi\u0144ska R, D\u0105browska K, \u015awis\u0142ocka R, Lewandowski W, \u015awiergiel AH (2021) Antimicrobial properties of mandelic acid, gallic acid and their derivatives. Mini rev med chem 21(17):2544\u20132550","journal-title":"Mini rev med chem"},{"issue":"12","key":"4316_CR46","first-page":"2502","volume":"12","author":"S Davidova","year":"2024","unstructured":"Davidova S, Galabov AS, Satchanska GJM (2024) Antibacterial, Antifungal. Antivir Activity, and Mechanisms of Action of Plant Polyphenols 12(12):2502","journal-title":"Antivir Activity, and Mechanisms of Action of Plant Polyphenols"},{"issue":"5","key":"4316_CR47","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.3390\/molecules27051741","volume":"27","author":"A Przybylska-Balcerek","year":"2022","unstructured":"Przybylska-Balcerek A, Szablewski T, Cegielska-Radziejewska R, G\u00f3ral T, Kurasiak-Popowska D, Stuper-Szablewska K (2022) Assessment of antimicrobial properties of phenolic acid extracts from grain infected with fungi from the genus fusarium. Mol 27(5):1741","journal-title":"Mol"},{"issue":"5","key":"4316_CR48","doi-asserted-by":"publisher","first-page":"2993","DOI":"10.1111\/jam.15756","volume":"133","author":"Y Cheng","year":"2022","unstructured":"Cheng Y, De Bank PA, Bolhuis A (2022) An in vitro and ex vivo wound infection model to test topical and systemic treatment with antibiotics. J Appl Microbiol 133(5):2993\u20133006","journal-title":"J Appl Microbiol"},{"issue":"9","key":"4316_CR49","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.3390\/biomedicines10092055","volume":"10","author":"DV Bhalani","year":"2022","unstructured":"Bhalani DV et al (2022) Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics. Biomedicines 10(9):2055","journal-title":"Biomedicines"},{"issue":"11","key":"4316_CR50","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3390\/md20110694","volume":"20","author":"DH Abdelkader","year":"2022","unstructured":"Abdelkader DH et al (2022) Insight into fucoidan-based PEGylated PLGA nanoparticles encapsulating methyl anthranilic acid: in vitro evaluation and in vivo anti-inflammatory study. Mar Drugs 20(11):694","journal-title":"Mar Drugs"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-025-04316-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-025-04316-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-025-04316-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T23:01:06Z","timestamp":1757199666000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-025-04316-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":50,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["4316"],"URL":"https:\/\/doi.org\/10.1007\/s00284-025-04316-9","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"type":"print","value":"0343-8651"},{"type":"electronic","value":"1432-0991"}],"subject":[],"published":{"date-parts":[[2025,6,18]]},"assertion":[{"value":"9 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Authors declare the absence of any conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The in vivo protocol was accepted by the research ethics committee of the faculty of pharmacy, Tanta University, Tanta, Egypt (TP\/RE\/1\/24 p-04).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"338"}}