{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T08:07:36Z","timestamp":1761293256934,"version":"build-2065373602"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Ministry of Education, Govt. of India, IISc, STARS Program","award":["SCHEME FOR TRANSFORMATIONAL AND ADVANCED RESEARCH IN SCIENCES (STARS-2)","IISc program (Grant No. MoE\/STARS\/2023-0297)","Govt of India"],"award-info":[{"award-number":["SCHEME FOR TRANSFORMATIONAL AND ADVANCED RESEARCH IN SCIENCES (STARS-2)","IISc program (Grant No. MoE\/STARS\/2023-0297)","Govt of India"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Curr Microbiol"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00284-025-04489-3","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T16:15:37Z","timestamp":1757952937000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Deciphering Autoantigen Signatures in Chikungunya Virus Infection Using Machine Learning: A Data-Driven Approach to Understand Host Immunity"],"prefix":"10.1007","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7515-6072","authenticated-orcid":false,"given":"Chaitra Mallasandra","family":"Krishnappa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1294-7149","authenticated-orcid":false,"given":"Shanker","family":"Govindaswamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1327-5487","authenticated-orcid":false,"given":"Anjali","family":"Ganjiwale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,15]]},"reference":[{"key":"4489_CR1","doi-asserted-by":"publisher","first-page":"1095549","DOI":"10.3389\/fpubh.2022.1095549","volume":"10","author":"L Cai","year":"2023","unstructured":"Cai L, Hu X, Liu S, Wang L, Lu H, Tu H, Tong Y (2023) The research progress of Chikungunya fever. Front Public Health 10:1095549","journal-title":"Front Public Health"},{"issue":"7","key":"4489_CR2","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/nrmicro2368","volume":"8","author":"O Schwartz","year":"2010","unstructured":"Schwartz O, Albert ML (2010) Biology and pathogenesis of chikungunya virus. Nat Rev Microbiol 8(7):491\u2013500","journal-title":"Nat Rev Microbiol"},{"issue":"8","key":"4489_CR3","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1111\/tmi.13906","volume":"28","author":"P Yodtaweepornanan","year":"2023","unstructured":"Yodtaweepornanan P, Pongsittisak W, Satpanich P (2023) Incidence and factors associated with chronic chikungunya arthritis following chikungunya virus infection. Trop Med Int Health 28(8):653\u2013659","journal-title":"Trop Med Int Health"},{"issue":"5","key":"4489_CR4","doi-asserted-by":"publisher","first-page":"104938","DOI":"10.1016\/j.idnow.2024.104938","volume":"54","author":"VG da Costa","year":"2017","unstructured":"da Costa VG, Saivish MV, Sinhorini PF, Nogueira ML, Rahal P (2017) A meta-analysis of Chikungunya virus in neurological disorders. Infect Dis Now 54(5):104938","journal-title":"Infect Dis Now"},{"issue":"3","key":"4489_CR5","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1172\/JCI84417","volume":"127","author":"LA Silva","year":"2017","unstructured":"Silva LA, Dermody TS (2017) Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies. J Clin Invest 127(3):737\u2013749","journal-title":"J Clin Invest"},{"issue":"1","key":"4489_CR6","doi-asserted-by":"publisher","first-page":"e0005318","DOI":"10.1371\/journal.pntd.0005318","volume":"11","author":"C Weber","year":"2017","unstructured":"Weber C, Berberich E, von Rhein C, Hen\u00df L, Hildt E, Schnierle BS (2017) Identification of functional determinants in the chikungunya virus E2 protein. PLoS Negl Trop Dis 11(1):e0005318","journal-title":"PLoS Negl Trop Dis"},{"issue":"7324","key":"4489_CR7","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1038\/nature09555","volume":"468","author":"JE Voss","year":"2010","unstructured":"Voss JE, Vaney MC, Duquerroy S, Vonrhein C, Girard-Blanc C, Crublet E, Thompson A, Bricogne G, Rey FA (2010) Glycoprotein organization of Chikungunya virus particles revealed by x-ray crystallography. Nature 468(7324):709\u2013712","journal-title":"Nature"},{"issue":"10","key":"4489_CR8","doi-asserted-by":"publisher","first-page":"5914","DOI":"10.4049\/jimmunol.0900255","volume":"184","author":"JJ Hoarau","year":"2010","unstructured":"Hoarau JJ, Jaffar Bandjee MC, Krejbich Trotot P, Das T, Li-Pat-Yuen G, Dassa B, Denizot M, Guichard E, Ribera A, Henni T, Tallet F, Moiton MP, Gauz\u00e8re BA, Bruniquet S, Jaffar Bandjee Z, Morbidelli P, Martigny G, Jolivet M, Gay F, Grandadam M, Tolou H, Vieillard V, Debr\u00e9 P, Autran B, Gasque P (2010) Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response. J Immunol 184(10):5914\u20135927","journal-title":"J Immunol"},{"issue":"7","key":"4489_CR9","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1038\/nrrheum.2012.64","volume":"8","author":"A Suhrbier","year":"2012","unstructured":"Suhrbier A, Jaffar-Bandjee MC, Gasque P (2012) Arthritogenic alphaviruses\u2014an overview. Nat Rev Rheumatol 8(7):420\u2013429","journal-title":"Nat Rev Rheumatol"},{"issue":"7","key":"4489_CR10","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1016\/j.cell.2019.04.008","volume":"177","author":"H Song","year":"2019","unstructured":"Song H, Zhao Z, Chai Y, Jin X, Li C, Yuan F, Liu S, Gao Z, Wang H, Song J, Vazquez L, Zhang Y, Tan S, Morel CM, Yan J, Shi Y, Qi J, Gao F, Gao GF (2019) Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. Cell 177(7):1714-1724.e12","journal-title":"Cell"},{"issue":"12","key":"4489_CR11","doi-asserted-by":"publisher","first-page":"615165","DOI":"10.3389\/fmicb.2021.615165","volume":"25","author":"L De Caluw\u00e9","year":"2021","unstructured":"De Caluw\u00e9 L, Coppens S, Vereecken K, Daled S, Dhaenens M, Van Ostade X, Deforce D, Ari\u00ebn KK, Bartholomeeusen K (2021) The CD147 Protein Complex Is Involved in Entry of Chikungunya Virus and Related Alphaviruses in Human Cells. Front Microbiol 25(12):615165","journal-title":"Front Microbiol"},{"issue":"5","key":"4489_CR12","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1128\/JVI.03116-13","volume":"88","author":"LA Silva","year":"2014","unstructured":"Silva LA, Khomandiak S, Ashbrook AW, Weller R, Heise MT, Morrison TE, Dermody TS (2014) A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization. J Virol 88(5):2385\u20132397","journal-title":"J Virol"},{"issue":"3","key":"4489_CR13","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/infdis\/jis368","volume":"206","author":"M Noret","year":"2012","unstructured":"Noret M, Herrero L, Rulli N, Rolph M, Smith PN, Li RW, Roques P, Gras G, Mahalingam S (2012) Interleukin 6, RANKL, and osteoprotegerin expression by chikungunya virus-infected human osteoblasts. J Infect Dis 206(3):455\u2013457","journal-title":"J Infect Dis"},{"issue":"4","key":"4489_CR14","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/s10123-023-00337-1","volume":"26","author":"MS Hakim","year":"2023","unstructured":"Hakim MS, Annisa L, Aman AT (2023) The evolution of chikungunya virus circulating in Indonesia: sequence analysis of the orf2 gene encoding the viral structural proteins. Int Microbiol 26(4):781\u2013790","journal-title":"Int Microbiol"},{"issue":"8","key":"4489_CR15","doi-asserted-by":"publisher","first-page":"e7862","DOI":"10.15252\/msb.20177862","volume":"14","author":"D Michlmayr","year":"2018","unstructured":"Michlmayr D, Pak TR, Rahman AH, Amir EAD, Kim EY, Kim-Schulze S, Harris E (2018) Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases. Mol Syst Biol 14(8):e7862","journal-title":"Mol Syst Biol"},{"key":"4489_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13059-017-1382-0","volume":"19","author":"FA Wolf","year":"2018","unstructured":"Wolf FA, Angerer P, Theis FJ (2018) Scanpy: large-scale single-cell gene expression data analysis. Genome Biol 19:1\u20135","journal-title":"Genome Biol"},{"key":"4489_CR17","first-page":"2825","volume":"12","author":"F Pedregosa","year":"2011","unstructured":"Pedregosa F, Varoquaux G, Gramfort A, Michel V, Thirion B, Grisel O et al (2011) Scikit-learn: machine learning in python. J Mach Learn Res 12:2825\u20132830","journal-title":"J Mach Learn Res"},{"key":"4489_CR18","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s12864-019-6413-7","volume":"21","author":"D Chicco","year":"2020","unstructured":"Chicco D, Jurman G (2020) The advantages of the Matthews correlation coefficient (MCC) over F1 score and accuracy in binary classification evaluation. BMC Genomics 21:6. https:\/\/doi.org\/10.1186\/s12864-019-6413-7","journal-title":"BMC Genomics"},{"issue":"D1","key":"4489_CR19","doi-asserted-by":"publisher","first-page":"D769","DOI":"10.1093\/nar\/gkw946","volume":"45","author":"D Wang","year":"2017","unstructured":"Wang D, Yang L, Zhang P, LaBaer J, Hermjakob H, Li D, Yu X (2017) Aagatlas 1.0: a human autoantigen database. Nucleic Acids Res 45(D1):D769\u2013D776","journal-title":"Nucleic Acids Res"},{"issue":"suppl_2","key":"4489_CR20","doi-asserted-by":"publisher","first-page":"W214","DOI":"10.1093\/nar\/gkq537","volume":"38","author":"D Warde-Farley","year":"2010","unstructured":"Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, Morris Q (2010) The genemania prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res 38(suppl_2):W214\u2013W220","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"4489_CR21","doi-asserted-by":"publisher","first-page":"e90","DOI":"10.1002\/cpz1.90","volume":"1","author":"Z Xie","year":"2021","unstructured":"Xie Z, Bailey A, Kuleshov MV, Clarke DJ, Evangelista JE, Jenkins SL, Ma\u2019ayan A (2021) Gene set knowledge discovery with Enrichr. Current protocols 1(3):e90","journal-title":"Current protocols"},{"issue":"W1","key":"4489_CR22","doi-asserted-by":"publisher","first-page":"W234","DOI":"10.1093\/nar\/gkz240","volume":"47","author":"G Zhou","year":"2019","unstructured":"Zhou G, Soufan O, Ewald J, Hancock RE, Basu N, Xia J (2019) Networkanalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis. Nucleic Acids Res 47(W1):W234\u2013W241","journal-title":"Nucleic Acids Res"},{"issue":"22","key":"4489_CR23","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1093\/bioinformatics\/btq562","volume":"26","author":"J Montojo","year":"2010","unstructured":"Montojo J, Zuberi K, Rodriguez H, Kazi F, Wright G, Donaldson SL, Bader GD (2010) GeneMANIA cytoscape plugin: fast gene function predictions on the desktop. Bioinformatics 26(22):2927\u20132928","journal-title":"Bioinformatics"},{"issue":"W1","key":"4489_CR24","doi-asserted-by":"publisher","first-page":"W168","DOI":"10.1093\/nar\/gkad393","volume":"51","author":"JE Evangelista","year":"2023","unstructured":"Evangelista JE, Xie Z, Marino GB, Nguyen N, Clarke DJ, Ma\u2019ayan A (2023) Enrichr-KG: bridging enrichment analysis across multiple libraries. Nucleic Acids Res 51(W1):W168\u2013W179","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"4489_CR25","first-page":"D845","volume":"48","author":"J Pi\u00f1ero","year":"2020","unstructured":"Pi\u00f1ero J, Ram\u00edrez-Anguita JM, Sa\u00fcch-Pitarch J, Ronzano F, Centeno E, Sanz F, Furlong LI (2020) The DisGeNET knowledge platform for disease genomics. Nucleic Acids Res 48(D1):D845\u2013D855","journal-title":"Nucleic Acids Res"},{"key":"4489_CR26","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/s41586-022-05575-3","volume":"613","author":"JL Johnson","year":"2023","unstructured":"Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM et al (2023) An atlas of substrate specificities for the human serine\/threonine kinome. Nature 613:759\u2013766","journal-title":"Nature"},{"key":"4489_CR27","doi-asserted-by":"publisher","first-page":"D380","DOI":"10.1093\/nar\/gkx1013","volume":"46","author":"H Han","year":"2018","unstructured":"Han H, Cho JW, Lee S, Yun A, Kim H, Bae D, Yang S, Kim CY, Lee M, Kim E et al (2018) TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions. Nucleic Acids Res 46:D380\u2013D386","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"4489_CR28","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1007\/s00705-013-1602-1","volume":"158","author":"J Rana","year":"2013","unstructured":"Rana J, Sreejith R, Gulati S, Bharti I, Jain S, Gupta S (2013) Deciphering the host-pathogen protein interface in chikungunya virus-mediated sickness. Arch Virol 158(6):1159\u20131172","journal-title":"Arch Virol"},{"issue":"11","key":"4489_CR29","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.3390\/v12111252","volume":"12","author":"T Lin","year":"2020","unstructured":"Lin T, Geng T, Harrison AG, Yang D, Vella AT, Fikrig E, Wang P (2020) CXCL10 signaling contributes to the pathogenesis of arthritogenic alphaviruses. Viruses 12(11):1252. https:\/\/doi.org\/10.3390\/v12111252","journal-title":"Viruses"},{"issue":"3","key":"4489_CR30","doi-asserted-by":"publisher","first-page":"e91","DOI":"10.1016\/j.amjmed.2019.10.005","volume":"133","author":"JK Amaral","year":"2020","unstructured":"Amaral JK, Bilsborrow JB, Schoen RT (2020) Chronic chikungunya arthritis and rheumatoid arthritis: what they have in common. Am J Med 133(3):e91\u2013e97","journal-title":"Am J Med"},{"issue":"1","key":"4489_CR31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41572-023-00429-2","volume":"9","author":"K Bartholomeeusen","year":"2023","unstructured":"Bartholomeeusen K, Daniel M, LaBeaud DA, Gasque P, Peeling RW, Stephenson KE, Ari\u00ebn KK (2023) Chikungunya fever. Nat Rev Dis Primers 9(1):17","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"4489_CR32","doi-asserted-by":"publisher","first-page":"e1978","DOI":"10.1002\/rmv.1978","volume":"28","author":"R Mehta","year":"2018","unstructured":"Mehta R, Gerardin P, de Brito CAA, Soares CN, Ferreira MLB, Solomon T (2018) The neurological complications of chikungunya virus: A systematic review. Rev Med Virol 28(3):e1978. https:\/\/doi.org\/10.1002\/rmv.1978","journal-title":"Rev Med Virol"},{"issue":"6","key":"4489_CR33","doi-asserted-by":"publisher","first-page":"jcs260743","DOI":"10.1242\/jcs.260743","volume":"136","author":"T Welz","year":"2023","unstructured":"Welz T, Kerkhoff E (2023) The role of SPIRE actin nucleators in cellular transport processes. J Cell Sci 136(6):jcs260743","journal-title":"J Cell Sci"},{"issue":"2","key":"4489_CR34","doi-asserted-by":"publisher","first-page":"e1010277","DOI":"10.1371\/journal.ppat.1010277","volume":"18","author":"AA Torres","year":"2022","unstructured":"Torres AA, Macilwee SL, Rashid A, Cox SE, Albarnaz JD, Bonjardim CA, Smith GL (2022) The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling. PLoS Pathog 18(2):e1010277","journal-title":"PLoS Pathog"},{"key":"4489_CR35","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.meegid.2017.09.028","volume":"66","author":"A Mozzi","year":"2018","unstructured":"Mozzi A, Pontremoli C, Sironi M (2018) Genetic susceptibility to infectious diseases: current status and future perspectives from genome-wide approaches. Infect Genet Evol 66:286\u2013307","journal-title":"Infect Genet Evol"},{"issue":"2","key":"4489_CR36","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1042\/BST20160022","volume":"45","author":"IH Yaseen","year":"2017","unstructured":"Yaseen IH, Monk PN, Partridge LJ (2017) Tspan2: A tetraspanin protein involved in oligodendrogenesis and cancer metastasis. Biochem Soc Trans 45(2):465. https:\/\/doi.org\/10.1042\/BST20160022","journal-title":"Biochem Soc Trans"},{"issue":"6","key":"4489_CR37","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1038\/ng.2261","volume":"44","author":"PT Ellinor","year":"2012","unstructured":"Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, K\u00e4\u00e4b S (2012) Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet 44(6):670\u2013675","journal-title":"Nat Genet"},{"key":"4489_CR38","doi-asserted-by":"publisher","first-page":"921653","DOI":"10.3389\/fmicb.2023.921653","volume":"14","author":"U Saeed","year":"2023","unstructured":"Saeed U, Piracha ZZ (2023) PIN1 and PIN4 inhibition via parvulin impeders Juglone, PiB, ATRA, 6, 7, 4\u2032-THIF, KPT6566, and EGCG thwarted hepatitis B virus replication. Front Microbiol 14:921653","journal-title":"Front Microbiol"},{"issue":"12","key":"4489_CR39","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1038\/s10038-023-01192-8","volume":"68","author":"R Han","year":"2023","unstructured":"Han R, Chu M, Gao J, Wang J, Wang M, Ma Y, Zhang X (2023) Compound heterozygous variants of THG1L result in autosomal recessive cerebellar ataxia. J Hum Genet 68(12):843\u2013848","journal-title":"J Hum Genet"},{"issue":"2\u20133","key":"4489_CR40","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.mam.2012.10.011","volume":"34","author":"E Traiffort","year":"2013","unstructured":"Traiffort E, O Regan S, Ruat M (2013) The choline transporter-like family SLC44: properties and roles in human diseases. Mol Aspects Med 34(2\u20133):646\u2013654","journal-title":"Mol Aspects Med"},{"issue":"4","key":"4489_CR41","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1038\/s41388-021-02113-9","volume":"41","author":"C Demetriadou","year":"2022","unstructured":"Demetriadou C, Raoukka A, Charidemou E, Mylonas C, Michael C, Parekh S, Kirmizis A (2022) Histone n-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Oncogene 41(4):571\u2013585","journal-title":"Oncogene"},{"issue":"2","key":"4489_CR42","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.ajhg.2018.12.013","volume":"104","author":"C Coutton","year":"2019","unstructured":"Coutton C, Martinez G, Kherraf ZE, Amiri-Yekta A, Boguenet M, Saut A, He X, Zhang F, Cristou-Kent M, Escoffier J, Bidart M, Satre V, Conne B, Fourati Ben Mustapha S, Halouani L, Marrakchi O, Makni M, Latrous H, Kharouf M, Pernet-Gallay K, Bonhivers M, Hennebicq S, Rives N, Dulioust E, Tour\u00e9 A, Gourabi H, Cao Y, Zouari R, Hosseini SH, Nef S, Thierry-Mieg N, Arnoult C, Ray PF (2019) Bi-allelic mutations in ARMC2 lead to severe astheno-teratozoospermia due to sperm flagellum malformations in humans and mice. Am J Hum Genet 104(2):331\u2013340","journal-title":"Am J Hum Genet"},{"key":"4489_CR43","first-page":"18","volume":"88","author":"OH Minchenko","year":"2016","unstructured":"Minchenko OH, Tsymbal DO, Minchenko DO, Ratushna OO (2016) The role of the TNF receptors and apoptosis inducing ligands in tumor growth. Ukr Biokhim Zh 88:18\u201337","journal-title":"Ukr Biokhim Zh"},{"issue":"9","key":"4489_CR44","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/JVI.02251-17","volume":"92","author":"QQ He","year":"2018","unstructured":"He QQ, Ren S, Xia ZC, Cheng ZK, Peng NF, Zhu Y (2018) Fibronectin facilitates enterovirus 71 infection by mediating viral entry. J Virol 92(9):10\u20131128","journal-title":"J Virol"},{"issue":"3","key":"4489_CR45","doi-asserted-by":"publisher","first-page":"e0152721","DOI":"10.1371\/journal.pone.0152721","volume":"11","author":"S Ren","year":"2016","unstructured":"Ren S, Wang J, Chen L, Li Y, Wan S, Peng F, Gui E, Zhu Y (2016) Hepatitis B virus stimulated fibronectin facilitates viral maintenance and replication through two distinct mechanisms. PLoS ONE 11(3):e0152721","journal-title":"PLoS ONE"},{"key":"4489_CR46","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X251318620","author":"RS Beard Jr.","year":"2025","unstructured":"Beard RS Jr., Hoettels BA, McAllister JM, Meegan JE, Wertz TS, Self DA, Hrkach DE, Greiner D, Chapman K, Villalba N, Yang X, Cha BJ, Jorcyk CL, Oxford JT, Wu MH, Yuan SY (2025) Progression of experimental autoimmune encephalomyelitis in mice and neutrophil-mediated blood-brain barrier dysfunction requires non-muscle myosin light chain kinase. J Cereb Blood Flow Metab. https:\/\/doi.org\/10.1177\/0271678X251318620","journal-title":"J Cereb Blood Flow Metab"},{"issue":"15","key":"4489_CR47","doi-asserted-by":"publisher","first-page":"5619","DOI":"10.1128\/MCB.20.15.5619-5630.2000","volume":"20","author":"T Guan","year":"2000","unstructured":"Guan T, Kehlenbach RH, Schirmer EC, Kehlenbach A, Fan F, Clurman BE, Arnheim N, Gerace L (2000) Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Mol Cell Biol 20(15):5619\u20135630","journal-title":"Mol Cell Biol"},{"key":"4489_CR48","doi-asserted-by":"publisher","first-page":"S405","DOI":"10.1016\/j.joca.2021.02.525","volume":"29","author":"M van Hoolwerff","year":"2021","unstructured":"van Hoolwerff M, Ruiz AR, Suchiman E, Bouma MJ, Freund CM, Mummery CL, Meulenbelt I (2021) High impact mutation FN1 affects cartilage integrity via aberrant binding to collagen type II. Osteoarthritis Cartilage 29:S405\u2013S406","journal-title":"Osteoarthritis Cartilage"},{"issue":"45","key":"4489_CR49","doi-asserted-by":"publisher","first-page":"eabg8583","DOI":"10.1126\/sciadv.abg8583","volume":"7","author":"M van Hoolwerff","year":"2021","unstructured":"van Hoolwerff M, Rodr\u00edguez Ruiz A, Bouma M, Suchiman HED, Koning RI, Jost CR, Meulenbelt I (2021) High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II. Sci Adv 7(45):eabg8583","journal-title":"Sci Adv"},{"key":"4489_CR50","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.chom.2024.02.011","volume":"32","author":"WM de Souza","year":"2024","unstructured":"de Souza WM, Marcilio J et al (2024) Pathophysiology of chikungunya virus infection associated with fatal outcomes. Cell Host Microbe 32:606-622.e8. https:\/\/doi.org\/10.1016\/j.chom.2024.02.011","journal-title":"Cell Host Microbe"},{"key":"4489_CR51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/ar3744","volume":"14","author":"JJ van Beers","year":"2012","unstructured":"van Beers JJ, Willemze A, Stammen-Vogelzangs J, Drijfhout JW, Toes RE, Pruijn GJ (2012) Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles. Arthritis Res Ther 14:1\u201316","journal-title":"Arthritis Res Ther"}],"container-title":["Current Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-025-04489-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00284-025-04489-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00284-025-04489-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T08:02:35Z","timestamp":1761292955000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00284-025-04489-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,15]]},"references-count":51,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["4489"],"URL":"https:\/\/doi.org\/10.1007\/s00284-025-04489-3","relation":{},"ISSN":["0343-8651","1432-0991"],"issn-type":[{"type":"print","value":"0343-8651"},{"type":"electronic","value":"1432-0991"}],"subject":[],"published":{"date-parts":[[2025,9,15]]},"assertion":[{"value":"8 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest, financial or otherwise\n                      .","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Consent to Participate"}}],"article-number":"501"}}