{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:03:04Z","timestamp":1773324184562,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2011,10,30]],"date-time":"2011-10-30T00:00:00Z","timestamp":1319932800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathologe"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1007\/s00292-011-1474-7","type":"journal-article","created":{"date-parts":[[2011,10,28]],"date-time":"2011-10-28T06:58:56Z","timestamp":1319785136000},"page":"451-460","source":"Crossref","is-referenced-by-count":7,"title":["HPV-assoziiertes Karzinom des weiblichen Genitaltrakts","HPV-associated carcinomas of the female genital tract"],"prefix":"10.1007","volume":"32","author":[{"given":"M.","family":"Reuschenbach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Vinokurova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"von Knebel Doeberitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,10,30]]},"reference":[{"key":"1474_CR1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-0-387-46816-7_7","volume":"133","author":"Cameron","year":"2007","unstructured":"Cameron JE, Hagensee ME (2007) Human papillomavirus infection and disease in the HIV\u2009+ \u2009individual. Cancer Treat Res 133:185\u2013213","journal-title":"Cancer Treat Res"},{"key":"1474_CR2","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1101\/gad.9.19.2335","volume":"9","author":"Cheng","year":"1995","unstructured":"Cheng S, Schmidt-Grimminger DC, Murant T et al (1995) Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev 9:2335\u20132349","journal-title":"Genes Dev"},{"key":"1474_CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0042-6822(02)00143-5","volume":"307","author":"Day","year":"2003","unstructured":"Day PM, Lowy DR, Schiller JT (2003) Papillomaviruses infect cells via a clathrin-dependent pathway. Virology 307:1\u201311","journal-title":"Virology"},{"key":"1474_CR4","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.arcmed.2009.06.002","volume":"40","author":"von","year":"2009","unstructured":"von Knebel Doeberitz M, Vinokurova S (2009) Host factors in HPV-related carcinogenesis: cellular mechanisms controlling HPV infections. Arch Med Res 40:435\u2013442. doi 10.1016\/j.arcmed","journal-title":"Arch Med Res"},{"key":"1474_CR5","doi-asserted-by":"crossref","first-page":"125","DOI":"10.4161\/epi.3.3.6249","volume":"3","author":"Doerfler","year":"2008","unstructured":"Doerfler W (2008) In pursuit of the first recognized epigenetic signal-DNA methylation: a 1976 to 2008 synopsis. Epigenetics 3:125\u2013133 (6249 [pii])","journal-title":"Epigenetics"},{"key":"1474_CR6","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1042\/CS20050369","volume":"Sci","author":"Doorbar","year":"2006","unstructured":"Doorbar J (2006) Molecular biology of human papillomavirus infection and cervical cancer. Clin Sci (Lond) 110:525\u2013541. doi 10.1042\/CS\u00a020050369","journal-title":"Clin"},{"key":"1474_CR7","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nature05919","volume":"447","author":"Feinberg","year":"2007","unstructured":"Feinberg AP (2007) Phenotypic plasticity and the epigenetics of human disease. Nature 447:433\u2013440. doi 10.1038\/nature05919","journal-title":"Nature"},{"key":"1474_CR8","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1101\/gr.083550.108","volume":"19","author":"Fernandez","year":"2009","unstructured":"Fernandez AF, Rosales C, Lopez-Nieva P et al (2009) The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer. Genome Res 19:438\u2013451. doi 10.1101\/gr.083550.108","journal-title":"Genome Res"},{"key":"1474_CR9","doi-asserted-by":"crossref","first-page":"20458","DOI":"10.1073\/pnas.0908502106","volume":"106","author":"Kines","year":"2009","unstructured":"Kines RC, Thompson CD, Lowy DR et al (2009) The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding. Proc Natl Acad Sci U S A 106:20458\u201320463. doi 10.1073\/pnas.0908502106","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1474_CR10","first-page":"6132","volume":"59","author":"Klaes","year":"1999","unstructured":"Klaes R, Woerner SM, Ridder R et al (1999) Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes. Cancer Res 59:6132\u20136136","journal-title":"Cancer Res"},{"key":"1474_CR11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tibs.2005.12.008","volume":"31","author":"Klose","year":"2006","unstructured":"Klose RJ, Bird AP (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31:89\u201397 (S 0968-0004(05)00352-X [pii]; doi 10.1016\/j.tibs.2005.12.008)","journal-title":"Trends Biochem Sci"},{"key":"1474_CR12","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1073\/pnas.1009933108","volume":"108","author":"McLaughlin-Drubin","year":"2011","unstructured":"McLaughlin-Drubin ME, Crum CP, Munger K (2011) Human papillomavirus E7 oncoprotein induces KDM\u00a06\u00a0A and KDM\u00a06B histone demethylase expression and causes epigenetic reprogramming. Proc Natl Acad Sci U S A 108:2130\u20132135 (1009933108 [pii]; doi 10.1073\/pnas.1009933108)","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1474_CR13","doi-asserted-by":"crossref","first-page":"d641","DOI":"10.2741\/munger","volume":"7","author":"Munger","year":"2002","unstructured":"Munger K (2002) The role of human papillomaviruses in human cancers. Front Biosci 7:d641-d649","journal-title":"Front Biosci"},{"key":"1474_CR14","doi-asserted-by":"crossref","first-page":"4952","DOI":"10.1128\/JVI.75.10.4952-4953.2001","volume":"75","author":"Orth","year":"2001","unstructured":"Orth G, Favre M, Majewski S, Jablonska S (2001) Epidermodysplasia verruciformis defines a subset of cutaneous human papillomaviruses. J Virol 75:4952\u20134953","journal-title":"J Virol"},{"key":"1474_CR15","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/path.2192","volume":"212","author":"Pett","year":"2007","unstructured":"Pett M, Coleman N (2007) Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis? J Pathol 212:356\u2013367 (doi 10.1002\/path.2192)","journal-title":"J Pathol"},{"key":"1474_CR16","doi-asserted-by":"crossref","first-page":"e1000148","DOI":"10.1371\/journal.ppat.1000148","volume":"4","author":"Schelhaas","year":"2008","unstructured":"Schelhaas M, Ewers H, Rajamaki ML (2008) Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions. PLoS Pathog 4:e1000148 (doi 10.1371\/journal.ppat.1000148)","journal-title":"PLoS Pathog"},{"key":"1474_CR17","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/S0140-6736(07)61416-0","volume":"370","author":"Schiffman","year":"2007","unstructured":"Schiffman M, Castle PE, Jeronimo J et al (2007) Human papillomavirus and cervical cancer. Lancet 370:890\u2013907 (S 0140-6736(07)61416-0 [pii]; doi 10.1016\/S 0140-6736(07)61416-0)","journal-title":"Lancet"},{"key":"1474_CR18","doi-asserted-by":"crossref","first-page":"10970","DOI":"10.1128\/JVI.00998-07","volume":"81","author":"Selinka","year":"2007","unstructured":"Selinka HC, Florin L, Patel HD et al (2007) Inhibition of transfer to secondary receptors by heparan sulfate-binding drug or antibody induces noninfectious uptake of human papillomavirus. J Virol 81:10970\u201310980 (JVI.00998\u201307 [pii]; doi 10.1128\/JVI.00998\u201307)","journal-title":"J Virol"},{"key":"1474_CR19","doi-asserted-by":"crossref","first-page":"9922","DOI":"10.1128\/JVI.00988-07","volume":"81","author":"Smith","year":"2007","unstructured":"Smith JL, Campos SK, Ozbun MA (2007) Human papillomavirus type 31 uses a caveolin 1- and dynamin 2-mediated entry pathway for infection of human keratinocytes. J Virol 81:9922\u20139931 (JVI.00988\u201307 [pii]; doi 10.1128\/JVI.00988\u201307)","journal-title":"J Virol"},{"key":"1474_CR20","doi-asserted-by":"crossref","first-page":"9505","DOI":"10.1128\/JVI.01014-08","volume":"82","author":"Smith","year":"2008","unstructured":"Smith JL, Campos SK, Wandinger-Ness A, Ozbun MA (2008) Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoating. J Virol 82:9505\u201395120 (JVI.01014\u201308 [pii];10.1128\/JVI.01014\u201308 [doi])","journal-title":"J Virol"},{"key":"1474_CR21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0165-0378(01)00113-9","volume":"52","author":"Stanley","year":"2001","unstructured":"Stanley MA (2001) Immunobiology of papillomavirus infections. J Reprod Immunol 52:45\u201359 (S 0165037801001139 [pii])","journal-title":"J Reprod Immunol"},{"key":"1474_CR22","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1128\/JVI.71.1.50-58.1997","volume":"71","author":"Steger","year":"1997","unstructured":"Steger G, Corbach S (1997) Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 protein. J Virol 71:50\u201358","journal-title":"J Virol"},{"key":"1474_CR23","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/S0046-8177(86)80569-X","volume":"17","author":"Stoler","year":"1986","unstructured":"Stoler MH, Broker TR (1986) In situ hybridization detection of human papillomavirus DNAs and messenger RNAs in genital condylomas and a cervical carcinoma. Hum Pathol 17:1250\u20131258","journal-title":"Hum Pathol"},{"key":"1474_CR24","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0042-6822(89)90135-9","volume":"172","author":"Stoler","year":"1989","unstructured":"Stoler MH, Wolinsky SM, Whitbeck A et al (1989) Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes. Virology 172:331\u2013340","journal-title":"Virology"},{"key":"1474_CR25","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/jnci\/dji073","volume":"97","author":"Strickler","year":"2005","unstructured":"Strickler HD, Burk RD, Fazzari M et al (2005) Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women. J Natl Cancer Inst 97:577\u2013586 (97\/8\/577 [pii];10.1093\/jnci\/dji073 [doi])","journal-title":"J Natl Cancer Inst"},{"key":"1474_CR26","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.virol.2008.11.014","volume":"384","author":"Thierry","year":"2009","unstructured":"Thierry F (2009) Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma. Virology 384:375\u2013379 (S 0042\u20136822(08)00728\u20139 [pii];10.1016\/j.virol.2008.11.014 [doi])","journal-title":"Virology"},{"key":"1474_CR27","doi-asserted-by":"crossref","first-page":"e24451","DOI":"10.1371\/journal.pone.0024451","volume":"6","author":"Vinokurova","year":"2011","unstructured":"Vinokurova S, Knebel Doeberitz M von (2011) Differential methylation of the HPV16 upstream regulatory region during epithelial differentiation and neoplastic transformation. PLoS One 6:e24451","journal-title":"PLoS One"},{"key":"1474_CR28","doi-asserted-by":"crossref","unstructured":"Weissenborn S, Neale RE, Waterboer T et al (2011) Beta-papillomavirus DNA loads in hair follicles of immunocompetent people and organ transplant recipients. Med Microbiol Immunol (10.1007\/s00430\u2013011-0212\u20133 [doi])","DOI":"10.1007\/s00430-011-0212-3"},{"key":"1474_CR29","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0092-8674(04)00402-7","volume":"117","author":"You","year":"2004","unstructured":"You J, Croyle JL, Nishimura A et al (2004) Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 117:349\u2013360 (S 0092867404004027 [pii])","journal-title":"Cell"},{"key":"1474_CR30","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/jnci\/92.9.690","volume":"92","author":"zur","year":"2000","unstructured":"zur Hausen H (2000) Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 92:690\u2013698","journal-title":"J Natl Cancer Inst"},{"key":"1474_CR31","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.virol.2008.11.046","volume":"384","author":"zur","year":"2009","unstructured":"zur Hausen H (2009) Papillomaviruses in the causation of human cancers \u2013 a brief historical account. Virology 384:260\u2013265 (S 0042-6822(08)00772-1 [pii];10.1016\/j.virol.2008.11.046 [doi])","journal-title":"Virology"}],"container-title":["Der Pathologe"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-011-1474-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00292-011-1474-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-011-1474-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T17:32:33Z","timestamp":1593192753000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00292-011-1474-7"}},"subtitle":["Molekulare Mechanismen der Entstehung","Molecular mechanisms of development"],"short-title":[],"issued":{"date-parts":[[2011,10,30]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["1474"],"URL":"https:\/\/doi.org\/10.1007\/s00292-011-1474-7","relation":{},"ISSN":["0172-8113","1432-1963"],"issn-type":[{"value":"0172-8113","type":"print"},{"value":"1432-1963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,30]]}}}