{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:52:15Z","timestamp":1772891535456,"version":"3.50.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathologe"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1007\/s00292-021-00910-3","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T15:03:11Z","timestamp":1611241391000},"page":"71-77","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Histopathologie der Lungentuberkulose","Histopathology of pulmonary tuberculosis"],"prefix":"10.1007","volume":"42","author":[{"given":"Florian","family":"Stellmacher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Perner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"issue":"15","key":"910_CR1","first-page":"221","volume":"19","author":"R Koch","year":"1882","unstructured":"Koch\u00a0R (1882) Die Aetiologie der Tuberculose. Berl Klin Wochenschr 19(15):221\u2013230","journal-title":"Berl Klin Wochenschr"},{"key":"910_CR2","unstructured":"https:\/\/www.who.int\/health-topics\/tuberculosis. Zugegriffen: 30.10.2020"},{"key":"910_CR3","unstructured":"https:\/\/www.rki.de\/DE\/Content\/InfAZ\/T\/Tuberkulose\/Archiv_Berichte_TB_in_Dtl_tab.html. Zugegriffen: 30.10.2020"},{"key":"910_CR4","unstructured":"https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Merkblaetter\/Ratgeber_Tuberkulose.html. Zugegriffen: 30.10.2020"},{"key":"910_CR5","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s10405-010-0464-4","volume":"8","author":"E Vollmer","year":"2011","unstructured":"Vollmer\u00a0E, Goldmann\u00a0T (2011) Pathologie und Diagnose der Lungentuberkulose sowie nichttuberkul\u00f6ser Mykobakterien. Pneumologie 8:301\u2013305","journal-title":"Pneumologie"},{"issue":"4","key":"910_CR6","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1046\/j.1440-1843.2003.00513.x","volume":"8","author":"A Mert","year":"2003","unstructured":"Mert A, Ozaras R, Bilir M, Tabak F, Aki H, Ozturk R (2003) Ziehl-Neelsen staining and polymerase chain reaction study of tissue from tuberculous granulomas. Respirology 8(4):548","journal-title":"Respirology"},{"issue":"7","key":"910_CR7","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1164\/rccm.2111028","volume":"166","author":"H Fukunaga","year":"2002","unstructured":"Fukunaga\u00a0H, Murakami\u00a0T, Gondo\u00a0T, Sugi\u00a0K, Ishihara\u00a0T (2002) Sensitivity of acid-fast staining for Mycobacterium tuberculosis in formalin-fixed tissue. Am J Respir Crit Care Med 166(7):994\u2013997 (Oct)","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"910_CR8","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.jmoldx.2015.04.005","volume":"17","author":"YN Kim","year":"2015","unstructured":"Kim\u00a0YN, Kim\u00a0KM, Choi\u00a0HN, Lee\u00a0JH, Park\u00a0HS, Jang\u00a0KY, Moon\u00a0WS, Kang\u00a0MJ, Lee\u00a0DG, Chung\u00a0MJ (2015) Clinical usefulness of PCR for differential diagnosis of tuberculosis and nontuberculous mycobacterial infection in paraffin-embedded lung tissues. J\u00a0Mol Diagn 17(5):597\u2013604","journal-title":"J Mol Diagn"},{"issue":"9","key":"910_CR9","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1078\/0344-0338-00470","volume":"199","author":"R Sen Gupta","year":"2003","unstructured":"Sen Gupta\u00a0R, Hillemann\u00a0D, Kubica\u00a0T, Zissel\u00a0G, M\u00fcller-Quernheim\u00a0J, Galle\u00a0J, Vollmer\u00a0E, Goldmann\u00a0T (2003) HOPE-fixation enables improved PCR-based detection and differentiation of Mycobacterium tuberculosis complex in paraffin-embedded tissues. Pathol Res Pract 199(9):619\u2013623","journal-title":"Pathol Res Pract"},{"issue":"3","key":"910_CR10","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1309\/AJCP2QZRH4ZNPRDD","volume":"142","author":"AN Seo","year":"2014","unstructured":"Seo\u00a0AN, Park\u00a0HJ, Lee\u00a0HS, Park\u00a0JO, Chang\u00a0HE, Nam\u00a0KH, Choe\u00a0G, Park\u00a0KU (2014) Performance characteristics of nested polymerase chain reaction vs real-time polymerase chain reaction methods for detecting mycobacterium tuberculosis complex in paraffin-embedded human tissues. Am J Clin Pathol 142(3):384\u2013390","journal-title":"Am J Clin Pathol"},{"issue":"4","key":"910_CR11","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.jmoldx.2011.02.004","volume":"13","author":"HS Lee","year":"2011","unstructured":"Lee\u00a0HS, Park\u00a0KU, Park\u00a0JO, Chang\u00a0HE, Song\u00a0J, Choe\u00a0G (2011) Rapid, sensitive, and specific detection of mycobacterium tuberculosis complex by real-time PCR on paraffin-embedded human tissues. J\u00a0Mol Diagn 13(4):390\u2013394","journal-title":"J Mol Diagn"},{"issue":"6","key":"910_CR12","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1053\/j.semdp.2017.06.003","volume":"34","author":"D Jain","year":"2017","unstructured":"Jain\u00a0D, Ghosh\u00a0S, Teixeira\u00a0L, Mukhopadhyay\u00a0S (2017) Pathology of pulmonary tuberculosis and non-tuberculous mycobacterial lung disease: facts, misconceptions, and practical tips for pathologists. Semin Diagn Pathol 34(6):518\u2013529","journal-title":"Semin Diagn Pathol"},{"issue":"3","key":"910_CR13","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/S0962-8479(96)90008-8","volume":"77","author":"G Di Perri","year":"1996","unstructured":"Di Perri\u00a0G, Cazzadori\u00a0A, Vento\u00a0S, Bonora\u00a0S, Malena\u00a0M, Bontempini\u00a0L, Lanzafame\u00a0M, Allegranzi\u00a0B, Concia\u00a0E (1996) Comparative histopathological study of pulmonary tuberculosis in human immunodeficiency virus-infected and non-infected patients. Tuber Lung Dis 77(3):244\u2013249","journal-title":"Tuber Lung Dis"},{"issue":"3","key":"910_CR14","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s00428-005-1233-3","volume":"447","author":"C Schewe","year":"2005","unstructured":"Schewe\u00a0C, Goldmann\u00a0T, Grosser\u00a0M, Zink\u00a0A, Schl\u00fcns\u00a0K, Pahl\u00a0S, Ulrichs\u00a0T, Kaufmann\u00a0SH, Nerlich\u00a0A, Baretton\u00a0GB, Dietel\u00a0M, Vollmer\u00a0E, Petersen\u00a0I (2005) Inter-laboratory validation of PCR-based detection of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissues. Virchows Arch 447(3):573\u2013585. https:\/\/doi.org\/10.1007\/s00428-005-1233-3","journal-title":"Virchows Arch"},{"issue":"12","key":"910_CR15","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/S1473-3099(04)01206-X","volume":"4","author":"M Pai","year":"2004","unstructured":"Pai\u00a0M, Riley\u00a0LW, Colford\u00a0JM Jr. (2004) Interferon-gamma assays in the immunodiagnosis of tuberculosis: a\u00a0systematic review. Lancet Infect Dis 4(12):761\u2013776. https:\/\/doi.org\/10.1016\/S1473-3099(04)01206-X","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"910_CR16","doi-asserted-by":"publisher","first-page":"1702189","DOI":"10.1183\/13993003.02189-2017","volume":"51","author":"C Jafari","year":"2018","unstructured":"Jafari\u00a0C, Olaru\u00a0ID, Daduna\u00a0F, Ernst\u00a0M, Heyckendorf\u00a0J, Lange\u00a0C, Kalsdorf\u00a0B (2018) Rapid diagnosis of pulmonary tuberculosis by combined molecular and immunological methods. Eur Respir\u00a0J 51(5):1702189. https:\/\/doi.org\/10.1183\/13993003.02189-2017","journal-title":"Eur Respir J"},{"issue":"2","key":"910_CR17","first-page":"S92","volume":"18","author":"M Kuhns","year":"2020","unstructured":"Kuhns\u00a0M, Kohl\u00a0TA, Maurer\u00a0FP, Niemann\u00a0S (2020) Mikrobiologische Diagnostik der Tuberkulose \u2013 Altbew\u00e4hrte und neue Verfahren. Trilium Diagn 18(2):S92\u2013S95","journal-title":"Trilium Diagn"},{"key":"910_CR18","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.meegid.2018.11.021","volume":"72","author":"D Machado","year":"2019","unstructured":"Machado\u00a0D, Couto\u00a0I, Viveiros\u00a0M (2019) Advances in the molecular diagnosis of tuberculosis: from probes to genomes. Infect Genet Evol 72:93\u2013112. https:\/\/doi.org\/10.1016\/j.meegid.2018.11.021","journal-title":"Infect Genet Evol"},{"issue":"9","key":"910_CR19","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/s41579-019-0214-5","volume":"17","author":"CJ Meehan","year":"2019","unstructured":"Meehan\u00a0CJ, Goig\u00a0GA, Kohl\u00a0TA, Verboven\u00a0L, Dippenaar\u00a0A, Ezewudo\u00a0M, Farhat\u00a0MR, Guthrie\u00a0JL, Laukens\u00a0K, Miotto\u00a0P, Ofori-Anyinam\u00a0B, Dreyer\u00a0V, Supply\u00a0P, Suresh\u00a0A, Utpatel\u00a0C, van Soolingen\u00a0D, Zhou\u00a0Y, Ashton\u00a0PM, Brites\u00a0D, Cabibbe\u00a0AM, de Jong\u00a0BC, de Vos\u00a0M, Menardo\u00a0F, Gagneux\u00a0S, Gao\u00a0Q, Heupink\u00a0TH, Liu\u00a0Q, Loiseau\u00a0C, Rigouts\u00a0L, Rodwell\u00a0TC, Tagliani\u00a0E, Walker\u00a0TM, Warren\u00a0RM, Zhao\u00a0Y, Zignol\u00a0M, Schito\u00a0M, Gardy\u00a0J, Cirillo\u00a0DM, Niemann\u00a0S, Comas\u00a0I, Van Rie\u00a0A (2019) Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues. Nat Rev Microbiol 17(9):533\u2013545. https:\/\/doi.org\/10.1038\/s41579-019-0214-5","journal-title":"Nat Rev Microbiol"},{"key":"910_CR20","first-page":"16","volume-title":"Tuberkulose und nicht tuberkul\u00f6se Mykobakteriosen heute","author":"S Ewig","year":"2011","unstructured":"Ewig\u00a0S, Schaberg\u00a0T, R\u00fcsch-Gerdes\u00a0S, Bollow\u00a0M (2011) Tuberkulose und nicht tuberkul\u00f6se Mykobakteriosen heute, 3.\u00a0Aufl. Dustri Verlag, Dr. Karl Feistle, M\u00fcnchen-Deisenhofen, S 16\u201367. ISBN 978-3-87185-405-7","edition":"3"},{"key":"910_CR21","doi-asserted-by":"crossref","unstructured":"Stellmacher, Perner (2021) \u00dcbersicht: Granulomat\u00f6se Erkrankungen der Lunge","DOI":"10.1007\/s00292-020-00893-7"},{"key":"910_CR22","doi-asserted-by":"crossref","unstructured":"Stellmacher et\u00a0al (2021) Molekuarpathologie der Tuberkulose","DOI":"10.1007\/s00292-021-00911-2"}],"container-title":["Der Pathologe"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-021-00910-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00292-021-00910-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-021-00910-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T11:58:20Z","timestamp":1612353500000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00292-021-00910-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,21]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["910"],"URL":"https:\/\/doi.org\/10.1007\/s00292-021-00910-3","relation":{},"ISSN":["0172-8113","1432-1963"],"issn-type":[{"value":"0172-8113","type":"print"},{"value":"1432-1963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,21]]},"assertion":[{"value":"4 January 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F.\u00a0Stellmacher und S.\u00a0Perner geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}