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Neben der Lunge sind auch andere Organe betroffen, welche die Morbidit\u00e4t und Mortalit\u00e4t deutlich beeinflussen k\u00f6nnen. Insbesondere neurologische Symptome unter Beteiligung des zentralen und peripheren Nervensystems k\u00f6nnen akute Symptome oder Langzeitfolgen ausl\u00f6sen. Die Mechanismen dieser Neuropathogenese der SARS-CoV-2-Infektion und ihr Zusammenhang mit akuten und chronischen neurologischen Symptomen sind Gegenstand aktueller Studien, die sich mit der Untersuchung einer potenziellen direkten und indirekten Virusinfektion des Nervensystems besch\u00e4ftigen. In der folgenden \u00dcbersichtsarbeit wird der aktuelle Stand \u00fcber die neuropathologischen Manifestationen, die molekulare Pathogenese, die m\u00f6glichen Infektionswege im Nervensystem und die systemischen Wirkungen zusammengefasst. 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