{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:40:52Z","timestamp":1762508452682},"reference-count":78,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathologe"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1007\/s00292-021-00932-x","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T09:03:36Z","timestamp":1618909416000},"page":"333-351","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["WHO-Klassifikation der Hypophysentumoren des Jahres 2017","The 2017 WHO classification of pituitary tumors"],"prefix":"10.1007","volume":"42","author":[{"given":"Wolfgang","family":"Saeger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"key":"932_CR1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1055\/a-1310-7900","volume":"129","author":"W Saeger","year":"2021","unstructured":"Saeger\u00a0W, Koch\u00a0A (2021) Review: clinical implications of the new WHO classification 2017 for pituitary tumors. Exp Clin Endocrinol Diabetes 129:146\u2013156","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"932_CR2","first-page":"251","volume":"18","author":"C Souchier","year":"1996","unstructured":"Souchier\u00a0C, Guigard\u00a0MP, Fonlupt\u00a0P, Trouillas\u00a0J (1996) Quantitative evaluation of the distribution of cell density\u2014application to human pituitary corticotroph cells. Anal Quant Cytol Histol 18:251\u2013260","journal-title":"Anal. Quant. Cytol. Histol."},{"key":"932_CR3","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/00005072-198209000-00002","volume":"41","author":"PE McKeever","year":"1982","unstructured":"McKeever\u00a0PE, Koppelman\u00a0MCS, Metcalf\u00a0D, Quindlen\u00a0E, Kornblith\u00a0PL, Strott\u00a0CA, Howard\u00a0R, Smith\u00a0BH (1982) Refractory cushing\u2019s disease caused by multinodular ACTH-cell hyperplasia. J\u00a0Neuropathol Exp Neurol 41:490\u2013499","journal-title":"J Neuropathol Exp Neurol"},{"key":"932_CR4","first-page":"484","volume":"107","author":"BW Scheithauer","year":"1983","unstructured":"Scheithauer\u00a0BW, Kovacs\u00a0K, Randall\u00a0RV (1983) The pituitary gland in untreated Addison\u2019s disease. A histologic and immunocytologic study of 18 adenohypophyses. Arch Pathol Lab Med 107:484\u2013487","journal-title":"Arch. Pathol. Lab. Med."},{"key":"932_CR5","first-page":"499","volume":"109","author":"BW Scheithauer","year":"1985","unstructured":"Scheithauer\u00a0BW, Kovacs\u00a0K, Randall\u00a0RV, Ryan\u00a0N (1985) Pituitary gland in hypothyroidism. Histologic and immunocytologic study. Arch Pathol Lab Med 109:499\u2013504","journal-title":"Arch. Pathol. Lab. Med."},{"key":"932_CR6","first-page":"141","volume":"6","author":"W Saeger","year":"1985","unstructured":"Saeger\u00a0W, Schr\u00f6der\u00a0H (1985) ACTH-Zellhyperplasien der Adeno- und der Neurohypophyse und ihre Beziehungen zur arteriellen Hypertonie. Pathologe 6:141\u2013148","journal-title":"Pathologe"},{"key":"932_CR7","first-page":"1","volume-title":"Tumors of the pituitary gland","author":"SL Asa","year":"1998","unstructured":"Asa\u00a0SL (1998) Tumors of the pituitary gland. Armed Forces Institute of Pathology, Washington, D.C., S\u00a01\u2013210"},{"key":"932_CR8","first-page":"1","volume-title":"Tumors of the pituitary gland","author":"K Kovacs","year":"1986","unstructured":"Kovacs\u00a0K, Horvath\u00a0E (1986) Tumors of the pituitary gland. Armed Forces Institute of Pathology, Washington, D.C., S\u00a01\u2013269"},{"key":"932_CR9","first-page":"9","volume-title":"Pathology and Genetics. Tumours of Endocrine Tumours","author":"RV Lloyd","year":"2004","unstructured":"Lloyd\u00a0RV, Kovacs\u00a0K, Young\u00a0WF\u00a0Jr., Farrell\u00a0WE, Asa\u00a0SL, Trouillas\u00a0J, Kontogeorgos\u00a0G, Sano\u00a0T, Scheithauer\u00a0BW, Horvath\u00a0E, Watson\u00a0RE\u00a0Jr., Lindell\u00a0EP, Barkan\u00a0AL, Saeger\u00a0W, Nos\u00e9\u00a0V, Osamura\u00a0RY, Ezzat\u00a0S, Yamada\u00a0S, Roncaroli\u00a0F, Lopes\u00a0MBS, Ruibal\u00a0VS (2004) Tumours of the pituitary. In: DeLellis\u00a0RA, Lloyd\u00a0RV, Heitz\u00a0PU (Hrsg) Pathology and Genetics. Tumours of Endocrine Tumours, 1.\u00a0Aufl. IARC, Lyon, S\u00a09\u201348","edition":"1"},{"key":"932_CR10","first-page":"1275","volume":"77","author":"SL Asa","year":"1993","unstructured":"Asa\u00a0SL, Puy\u00a0LA, Lew\u00a0AM, Sundmark\u00a0VC, Elsholtz\u00a0HP (1993) Cell type-specific expression of the pituitary transcription activator pit\u20111 in the human pituitary and pituitary adenomas. J Clin Endocrinol Metab 77:1275\u20131280","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"932_CR11","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-017-1768-9","author":"E Sj\u00f6stedt","year":"2017","unstructured":"Sj\u00f6stedt\u00a0E, Bollerslev\u00a0J, Mulder\u00a0J, Lindskog\u00a0C, Ponten\u00a0F, Casar-Borota\u00a0O (2017) A specific antibody to detect transcription factor T\u2011pit: a\u00a0reliable marker of corticotroph cell differentiation and a\u00a0tool to improve the classification of pituitary neuroendocrine tumours. Acta Neuropathol. https:\/\/doi.org\/10.1007\/s00401-017-1768-9","journal-title":"Acta Neuropathol."},{"key":"932_CR12","first-page":"2165","volume":"81","author":"SL Asa","year":"1996","unstructured":"Asa\u00a0SL, Bamberger\u00a0AM, Cao\u00a0B, Wong\u00a0M, Parker\u00a0KL, Ezzat\u00a0S (1996) The transcription activator steroidogenic factor\u20111 is preferentially expressed in the human pituitary gonadotroph. J\u00a0Clin Endocrinol Metab 81:2165\u20132170","journal-title":"J Clin Endocrinol Metab"},{"key":"932_CR13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/s12022-017-9498-z","volume":"28","author":"O Mete","year":"2017","unstructured":"Mete\u00a0O, Lopes\u00a0MB (2017) Overview of the 2017 WHO classification of pituitary tumors. Endocr Pathol 28:228\u2013243","journal-title":"Endocr Pathol"},{"key":"932_CR14","unstructured":"Saeger, W, Buslei, R: Data of the German Pituitary Tumor Registry in 2018 according to the new WHO classification of 2017, 2020. (UnPub)"},{"key":"932_CR15","first-page":"3621","volume":"80","author":"M Zafar","year":"1995","unstructured":"Zafar\u00a0M, Ezzat\u00a0S, Ramyar\u00a0L, Pan\u00a0N, Smyth\u00a0HS, Asa\u00a0SL (1995) Cell-specific expression of estrogen receptor in the human pituitary and its adenomas. J Clin Endocrinol Metab 80:3621\u20133627","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"932_CR16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/1097-0142(19810215)47:4<761::AID-CNCR2820470422>3.0.CO;2-L","volume":"47","author":"E Horvath","year":"1981","unstructured":"Horvath\u00a0E, Kovacs\u00a0K, Singer\u00a0W, Smyth\u00a0HS, Killinger\u00a0DW, Erzin\u00a0C, Weiss\u00a0MH (1981) Acidophil stem-cell adenoma of the human pituitary\u2014clinicopathologic analysis of 15 cases. Cancer 47:761\u2013771","journal-title":"Cancer"},{"key":"932_CR17","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s12020-016-0863-3","volume":"52","author":"FG Amlashi","year":"2016","unstructured":"Amlashi\u00a0FG, Tritos\u00a0NA (2016) Thyrotropin-secreting pituitary adenomas: epidemiology, diagnosis, and management. Endocrine 52:427\u2013440","journal-title":"Endocrine"},{"key":"932_CR18","first-page":"91","volume-title":"Diagnosis and management pituitary tumors","author":"BW Scheithauer","year":"2001","unstructured":"Scheithauer\u00a0BW, Horvath\u00a0E, Lloyd\u00a0RV, Kovacs\u00a0K (2001) Pathology of pituitary adenomas and pituitary hyperplasia. In: Thapar\u00a0K, Kovacs\u00a0K, Scheithauer\u00a0BW, Lloyd\u00a0RV (Hrsg) Diagnosis and management pituitary tumors, 1.\u00a0Aufl. Humana Press, Totowa, S\u00a091\u2013154","edition":"1"},{"key":"932_CR19","first-page":"245","volume-title":"Functional endocrine pathology","author":"E Horvath","year":"1991","unstructured":"Horvath\u00a0E, Kovacs\u00a0K (1991) The adenohypophysis. In: Kovacs\u00a0K, Asa\u00a0SL (Hrsg) Functional endocrine pathology. Blackwell, Oxford, London, Edinburgh, Melbourne, Paris, Berlin, Vienna, S\u00a0245\u2013282"},{"key":"932_CR20","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00430669","volume":"394","author":"W Saeger","year":"1982","unstructured":"Saeger\u00a0W, L\u00fcdecke\u00a0DK (1982) Pituitary adenomas with hyperfunction of TSH. Frequency, histological classification, immunocytochemistry and ultrastructure. Virchows Arch 394:255\u2013267","journal-title":"Virchows Arch"},{"key":"932_CR21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/path.1700410215","volume":"41","author":"AC Crooke","year":"1935","unstructured":"Crooke\u00a0AC (1935) A change in the basophil cells of the pituitary gland common to conditions which wxhibit the syndrome attributed to basophil adenoma. J\u00a0Pathol Bacteriol 41:339\u2013349","journal-title":"J Pathol Bacteriol"},{"key":"932_CR22","first-page":"1","volume-title":"Pathology and genetics: Tumours of endocrine organs (World Health Organization classification of tumours)","author":"RA DeLellis","year":"2004","unstructured":"DeLellis\u00a0RA, Lloyd\u00a0RV, Heitz\u00a0PU (2004) Pathology and genetics: Tumours of endocrine organs (World Health Organization classification of tumours), 1.\u00a0Aufl. International Agency for Research and Cancer (IARC), Lyon, S\u00a01\u2013311","edition":"1"},{"key":"932_CR23","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/BF00705414","volume":"409","author":"AM Landolt","year":"1986","unstructured":"Landolt\u00a0AM, Heitz\u00a0PU (1986) Alpha-subunit-producing pituitary adenomas. Immunocytochemical and ultrastructural studies. Virchows Arch A Pathol Anat Histopathol 409:417\u2013431","journal-title":"Virchows Arch. A. Pathol. Anat. Histopathol."},{"key":"932_CR24","first-page":"587","volume-title":"Urogenitale und endokrine Organe, Gelenke und Skelett","author":"W Saeger","year":"2015","unstructured":"Saeger\u00a0W (2015) Hypophyse. In: Amann\u00a0K, Kain\u00a0R, Kl\u00f6ppel\u00a0G (Hrsg) Urogenitale und endokrine Organe, Gelenke und Skelett, 3.\u00a0Aufl. Springer, Heidelberg, S\u00a0587\u2013630","edition":"3"},{"key":"932_CR25","first-page":"11","volume-title":"WHO classification of tumours of endocrine organs","author":"R Osamura","year":"2017","unstructured":"Osamura\u00a0R, Lopes\u00a0MBS, Grossman\u00a0A, Kontogeorgos\u00a0G, Trouillas\u00a0J (2017) Tumours of the pituitary gland. In: Lloyd\u00a0RV, Osamura\u00a0RY, Kl\u00f6ppel\u00a0G, Rosai\u00a0J (Hrsg) WHO classification of tumours of endocrine organs, 4.\u00a0Aufl. Springer, Heidelberg, Berlin, S\u00a011\u201364","edition":"4"},{"key":"932_CR26","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11102-017-0855-1","volume":"21","author":"E Manojlovic-Gacic","year":"2018","unstructured":"Manojlovic-Gacic\u00a0E, Engstrom\u00a0B, Casar-Borota\u00a0O (2018) Histopathological classification of non-functioning pituitary neuroendocrine tumors. Pituitary 21:119\u2013129","journal-title":"Pituitary"},{"key":"932_CR27","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1007\/s11102-019-00981-9","volume":"22","author":"JP Almeida","year":"2019","unstructured":"Almeida\u00a0JP, Stephens\u00a0CC, Eschbacher\u00a0JM, Felicella\u00a0MM, Yuen\u00a0KCJ, White\u00a0WL, Mooney\u00a0MA, Bernat\u00a0AL, Mete\u00a0O, Zadeh\u00a0G, Gentili\u00a0F, Little\u00a0AS (2019) Clinical, pathologic, and imaging characteristics of pituitary null cell adenomas as defined according to the 2017 World Health Organization criteria: a\u00a0case series from two pituitary centers. Pituitary 22:514\u2013519","journal-title":"Pituitary"},{"key":"932_CR28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s12022-014-9347-2","volume":"26","author":"JA Balogun","year":"2015","unstructured":"Balogun\u00a0JA, Monsalves\u00a0E, Juraschka\u00a0K, Parvez\u00a0K, Kucharczyk\u00a0W, Mete\u00a0O, Gentili\u00a0F, Zadeh\u00a0G (2015) Null cell adenomas of the pituitary gland: an institutional review of their clinical imaging and behavioral characteristics. Endocr Pathol 26:63\u201370","journal-title":"Endocr Pathol"},{"key":"932_CR29","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1080\/01913120500323514","volume":"29","author":"E Horvath","year":"2005","unstructured":"Horvath\u00a0E, Kovacs\u00a0K, Smyth\u00a0HS, Cusimano\u00a0M, Singer\u00a0W (2005) Silent adenoma subtype 3 of the pituitary\u2014Immunohistochemical and ultrastructural classification: a review of 29\u00a0cases. Ultrastruct Pathol 29:511\u2013524","journal-title":"Ultrastruct Pathol"},{"key":"932_CR30","first-page":"75","volume-title":"Molecular and cellular endocrine pathology","author":"L Stefaneanu","year":"2000","unstructured":"Stefaneanu\u00a0L, Kovacs\u00a0K, Horvath\u00a0E, Scheithauer\u00a0BW (2000) The adenohypophysis. In: Stefaneanu\u00a0L, Sasano\u00a0H, Kovacs\u00a0K (Hrsg) Molecular and cellular endocrine pathology, 1.\u00a0Aufl. Arnold, London, S\u00a075\u2013118","edition":"1"},{"key":"932_CR31","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s11102-018-0888-0","volume":"21","author":"A Nakhleh","year":"2018","unstructured":"Nakhleh\u00a0A, Shehadeh\u00a0N, Hochberg\u00a0I, Zloczower\u00a0M, Zolotov\u00a0S, Taher\u00a0R, Naccache\u00a0DD (2018) Management of cystic prolactinomas: a\u00a0review. Pituitary 21:425\u2013430","journal-title":"Pituitary"},{"key":"932_CR32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.wneu.2013.09.035","volume":"81","author":"EH Lee","year":"2014","unstructured":"Lee\u00a0EH, Kim\u00a0KH, Kwon\u00a0JH, Kim\u00a0HD, Kim\u00a0YZ (2014) Results of immunohistochemical staining of cell-cycle regulators: the prediction of recurrence of functioning pituitary adenoma. World Neurosurg 81:563\u2013575","journal-title":"World Neurosurg"},{"key":"932_CR33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1530\/EJE-15-0586","volume":"174","author":"A Coli","year":"2016","unstructured":"Coli\u00a0A, Asa\u00a0SL, Fadda\u00a0G, Scannone\u00a0D, Chiloiro\u00a0S, de Marinis\u00a0L, Lauretti\u00a0L, Ranelletti\u00a0FO, Lauriola\u00a0L (2016) Minichromosome maintenance protein 7 as prognostic marker of tumor aggressiveness in pituitary adenoma patients. Eur J Endocrinol 174:307\u2013314","journal-title":"Eur. J. Endocrinol."},{"key":"932_CR34","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nrendo.2014.64","volume":"10","author":"A Di Ieva","year":"2014","unstructured":"Di Ieva\u00a0A, Rotondo\u00a0F, Syro\u00a0LV, Cusimano\u00a0MD, Kovacs\u00a0K (2014) Aggressive pituitary adenomas-diagnosis and emerging treatments. Nat Rev Endocrinol 10:423\u2013435","journal-title":"Nat Rev Endocrinol"},{"key":"932_CR35","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1210\/jc.2011-1166","volume":"96","author":"K Dudziak","year":"2011","unstructured":"Dudziak\u00a0K, Honegger\u00a0J, Bornemann\u00a0A, Horger\u00a0M, Mussig\u00a0K (2011) Pituitary carcinoma with malignant growth from first presentation and fulminant clinical course-case report and review of the literature. J\u00a0Clin Endocrinol Metab 96:2665\u20132669","journal-title":"J Clin Endocrinol Metab"},{"key":"932_CR36","doi-asserted-by":"crossref","first-page":"C5","DOI":"10.1530\/ERC-17-0004","volume":"24","author":"SL Asa","year":"2017","unstructured":"Asa\u00a0SL, Casar-Borota\u00a0O, Chanson\u00a0P, Delgrange\u00a0E, Earls\u00a0P, Ezzat\u00a0S, Grossman\u00a0A, Ikeda\u00a0H, Inoshita\u00a0N, Karavitaki\u00a0N, Korbonits\u00a0M, Laws\u00a0ER, Lopes\u00a0MB, Maartens\u00a0N, McCutcheon\u00a0IE, Mete\u00a0O, Nishioka\u00a0H, Raverot\u00a0G, Roncaroli\u00a0F, Saeger\u00a0W, Syro\u00a0LV, Vasiljevic\u00a0A, Villa\u00a0C, Wierinckx\u00a0A, Trouillas\u00a0J (2017) From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal. Endocr Relat Cancer 24:C5\u2013C8","journal-title":"Endocr Relat Cancer"},{"key":"932_CR37","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s002920050236","volume":"18","author":"W Saeger","year":"1997","unstructured":"Saeger\u00a0W, L\u00fcdecke\u00a0DK, Losa\u00a0M (1997) Kombinierte neuronale und endokrine Tumoren der Sellaregion. Pathologe 18:419\u2013424","journal-title":"Pathologe"},{"key":"932_CR38","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00193956","volume":"425","author":"W Saeger","year":"1994","unstructured":"Saeger\u00a0W, Puchner\u00a0MJA, L\u00fcdecke\u00a0DK (1994) Combined sellar gangliocytoma and pituitary adenoma in acromegaly or Cushing\u2019s disease. A report of 3\u00a0cases. Virchows Arch 425:93\u201399","journal-title":"Virchows Arch"},{"key":"932_CR39","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1097\/PAS.0000000000000803","volume":"41","author":"C Sergeant","year":"2017","unstructured":"Sergeant\u00a0C, Jublanc\u00a0C, Leclercq\u00a0D, Boch\u00a0AL, Bielle\u00a0F, Raverot\u00a0G, Daly\u00a0AF, Trouillas\u00a0J, Villa\u00a0C (2017) Transdifferentiation of neuroendocrine cells gangliocytoma associated with two pituitary adenomas of different lineage in MEN1. Am J Surg Pathol 41:849\u2013853","journal-title":"Am J Surg Pathol"},{"key":"932_CR40","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/s12020-019-02033-5","volume":"66","author":"SS Pereira","year":"2019","unstructured":"Pereira\u00a0SS, Monteiro\u00a0MP, Costa\u00a0MM, Moreira\u00a0A, Alves\u00a0MG, Oliveira\u00a0PF, Jarak\u00a0I, Pignatelli\u00a0D (2019) IGF2 role in adrenocortical carcinoma biology. Endocrine 66:326\u2013337","journal-title":"Endocrine"},{"key":"932_CR41","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02921349","volume":"3","author":"JA Maguire","year":"1992","unstructured":"Maguire\u00a0JA, Bilbao\u00a0JM, Kovacs\u00a0K, Resch\u00a0L (1992) Hypothalamic neurocytoma with vasopressin Immunoreactivity\u2014Immunohistochemical and ultrastructural observations. Endocr Pathol 3:99\u2013104","journal-title":"Endocr Pathol"},{"key":"932_CR42","doi-asserted-by":"crossref","first-page":"953","DOI":"10.3171\/jns.1996.85.5.0953","volume":"85","author":"B Lach","year":"1996","unstructured":"Lach\u00a0B, Rippstein\u00a0P, Benoit\u00a0BG, Staines\u00a0W (1996) Differentiating neuroblastoma of pituitary gland: Neuroblastic transformation of epithelial adenoma cells\u2014Case report. J\u00a0Neurosurg 85:953\u2013960","journal-title":"J Neurosurg"},{"key":"932_CR43","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.clineuro.2011.04.002","volume":"113","author":"A Albert","year":"2011","unstructured":"Albert\u00a0A, Ramirez\u00a0JAR, Codere\u00a0F, Petrecca\u00a0K (2011) Sellar paraganglioma: a unique route to a\u00a0rare destination case report and literature review. Clin Neurol Neurosurg 113:675\u2013677","journal-title":"Clin Neurol Neurosurg"},{"key":"932_CR44","doi-asserted-by":"crossref","first-page":"E243","DOI":"10.1210\/jc.2010-1222","volume":"96","author":"HK Ghayee","year":"2011","unstructured":"Ghayee\u00a0HK, Rege\u00a0J, Watumull\u00a0LM, Nwariaku\u00a0FE, Carrick\u00a0KS, Rainey\u00a0WE, Miller\u00a0WL, Auchus\u00a0RJ (2011) Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome. J\u00a0Clin Endocrinol Metab 96:E243\u2013E250","journal-title":"J Clin Endocrinol Metab"},{"key":"932_CR45","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00401-006-0184-3","volume":"113","author":"R Buslei","year":"2007","unstructured":"Buslei\u00a0R, H\u00f6lsken\u00a0A, Hofmann\u00a0B, Kreutzer\u00a0J, Siebzehnrubl\u00a0F, Hans\u00a0V, Oppel\u00a0F, Buchfelder\u00a0M, Fahlbusch\u00a0R, Bl\u00fcmcke\u00a0I (2007) Nuclear beta-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas. Acta Neuropathol 113:585\u2013590","journal-title":"Acta Neuropathol"},{"key":"932_CR46","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s00401-005-1004-x","volume":"109","author":"R Buslei","year":"2005","unstructured":"Buslei\u00a0R, Nolde\u00a0M, Hofmann\u00a0B, Meissner\u00a0S, Eyupoglu\u00a0IY, Siebzehnrubl\u00a0F, Hahnen\u00a0E, Kreutzer\u00a0J, Fahlbusch\u00a0R (2005) Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region. Acta Neuropathol 109:589\u2013597","journal-title":"Acta Neuropathol"},{"key":"932_CR47","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1097\/01.pas.0000213328.64121.12","volume":"30","author":"BM Hofmann","year":"2006","unstructured":"Hofmann\u00a0BM, Kreutzer\u00a0J, Saeger\u00a0W, Buchfelder\u00a0M, Blumcke\u00a0I, Fahlbusch\u00a0R, Buslei\u00a0R (2006) Nuclear beta-catenin accumulation as reliable marker for the differentiation between cystic craniopharyngiomas and Rathke cleft cysts: a clinico-pathologic approach. Am J Surg Pathol 30:1595\u20131603","journal-title":"Am J Surg Pathol"},{"key":"932_CR48","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1016\/S0002-9440(10)64477-X","volume":"161","author":"S Sekine","year":"2002","unstructured":"Sekine\u00a0S, Shibata\u00a0T, Kokubu\u00a0A, Morishita\u00a0Y, Noguchi\u00a0M, Nakanishi\u00a0Y, Sakamoto\u00a0M, Hirohashi\u00a0S (2002) Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations. Am J Pathol 161:1997\u20132001","journal-title":"Am J. Pathol."},{"key":"932_CR49","doi-asserted-by":"crossref","first-page":"A2","DOI":"10.5414\/NPP29002","volume":"29","author":"M Ishida","year":"2010","unstructured":"Ishida\u00a0M, Hotta\u00a0M, Tsukamura\u00a0A, Taga\u00a0T, Kato\u00a0H, Ohta\u00a0S, Takeuchi\u00a0Y, Nakasu\u00a0S, Okabe\u00a0H (2010) Malignant transformation in craniopharyngioma after radiation therapy: a\u00a0case report and review of the literature. Clin Neuropathol 29:A2\u2013A8","journal-title":"Clin. Neuropathol."},{"key":"932_CR50","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1097\/PAS.0b013e31802d8a96","volume":"31","author":"FJ Rodriguez","year":"2007","unstructured":"Rodriguez\u00a0FJ, Scheithauer\u00a0BW, Tsunoda\u00a0S, Kovacs\u00a0K, Vidal\u00a0S, Piepgras\u00a0DG (2007) The spectrum of malignancy in craniopharyngioma. Am J Surg Pathol 31:1020\u20131028","journal-title":"Am J Surg Pathol"},{"key":"932_CR51","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1227\/NEU.0000000000000380","volume":"75","author":"AA Sofela","year":"2014","unstructured":"Sofela\u00a0AA, Hettige\u00a0S, Curran\u00a0O, Bassi\u00a0S (2014) Malignant transformation in craniopharyngiomas. Neurosurgery 75:306\u2013314","journal-title":"Neurosurgery"},{"key":"932_CR52","first-page":"249","volume":"24","author":"J Cao","year":"2010","unstructured":"Cao\u00a0J, Lin\u00a0JP, Yang\u00a0LX, Chen\u00a0K, Huang\u00a0ZS (2010) Expression of aberrant beta-catenin and impaired p63 in craniopharyngiomas. Br J Neurosurg 24:249\u2013256","journal-title":"Br J Neurosurg"},{"key":"932_CR53","doi-asserted-by":"crossref","first-page":"R139","DOI":"10.1530\/EJE-15-0957","volume":"174","author":"PK Brastianos","year":"2016","unstructured":"Brastianos\u00a0PK, Santagata\u00a0S (2016) BRAF V600E mutations in papillary craniopharyngioma. Eur J Endocrinol 174:R139\u2013R144","journal-title":"Eur J Endocrinol"},{"key":"932_CR54","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/nan.12201","volume":"41","author":"L Schweizer","year":"2015","unstructured":"Schweizer\u00a0L, Capper\u00a0D, Holsken\u00a0A, Fahlbusch\u00a0R, Flitsch\u00a0J, Buchfelder\u00a0M, Herold-Mende\u00a0C, von Deimling\u00a0A, Buslei\u00a0R (2015) BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke\u2019s cleft cysts. Neuropathol Appl Neurobiol 41:733\u2013742","journal-title":"Neuropathol Appl Neurobiol"},{"key":"932_CR55","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3171\/jns.2002.96.2.0209","volume":"96","author":"S Hama","year":"2002","unstructured":"Hama\u00a0S, Arita\u00a0K, Nishisaka\u00a0T, Fukuhara\u00a0T, Tominaga\u00a0A, Sugiyama\u00a0K, Yoshioka\u00a0H, Eguchi\u00a0K, Sumida\u00a0M, Heike\u00a0Y, Kurisu\u00a0K (2002) Changes in the epithelium of Rathke cleft cyst associated with inflammation. J\u00a0Neurosurg 96:209\u2013216","journal-title":"J Neurosurg"},{"key":"932_CR56","doi-asserted-by":"crossref","first-page":"83","DOI":"10.30802\/AALAS-CM-18-000137","volume":"70","author":"GJ Daggett","year":"2020","unstructured":"Daggett\u00a0GJ, Wood\u00a0JS, Gumber\u00a0S, Pinelli\u00a0CJ (2020) Spontaneous pituitary adenomas in squirrel monkeys (Saimiri sciureus). comp med 70:83\u201386","journal-title":"comp med"},{"key":"932_CR57","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.1016\/j.crad.2016.04.022","volume":"71","author":"ZI Hasiloglu","year":"2016","unstructured":"Hasiloglu\u00a0ZI, Ure\u00a0E, Comunoglu\u00a0N, Tanriover\u00a0N, Oz\u00a0B, Gazioglu\u00a0N, Mihmanli\u00a0I (2016) New radiological clues in the diagnosis of spindle cell oncocytoma of the adenohypophysis. Clin Radiol 71:E5","journal-title":"Clin Radiol"},{"key":"932_CR58","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1097\/PAS.0b013e31829723e7","volume":"37","author":"O Mete","year":"2013","unstructured":"Mete\u00a0O, Lopes\u00a0MB, Asa\u00a0SL (2013) Spindle cell Oncocytomas and granular cell tumors of the pituitary are variants of Pituicytoma. Am J Surg Pathol 37:1694\u20131699","journal-title":"Am J Surg Pathol"},{"key":"932_CR59","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1097\/00000478-200208000-00010","volume":"26","author":"F Roncaroli","year":"2002","unstructured":"Roncaroli\u00a0F, Scheithauer\u00a0BW, Cenacchi\u00a0G, Horvath\u00a0E, Kovacs\u00a0K, Lloyd\u00a0RV, Abell-Aleff\u00a0P, Santi\u00a0M, Yates\u00a0AJ (2002) Spindle cell oncocytoma\u2019 of the adenohypophysis\u2014A tumor of folliculostellate cells? Am J Surg Pathol 26:1048\u20131055","journal-title":"Am. J. Surg. Pathol."},{"key":"932_CR60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02688697.2018.1533107","volume":"15","author":"HM Witte","year":"2018","unstructured":"Witte\u00a0HM, Riecke\u00a0A, Saeger\u00a0W, Hackenbroch\u00a0C, Mathieu\u00a0R, Mauer\u00a0UM, Schulz\u00a0C (2018) Spindle cell oncocytoma of the neurohypophysis with metastasis to the sphenoparietal sinus and immunohistochemical negativity for S100 and Epithrelial Membrane Antigen (EMA). Br J Neurosurg 15:1\u20136","journal-title":"Br J Neurosurg"},{"key":"932_CR61","first-page":"141","volume-title":"Surgical pathology of the pituitary gland","author":"PE McKeever","year":"1993","unstructured":"McKeever\u00a0PE, Blaivas\u00a0M, Sima\u00a0AAF (1993) Neoplasms of the sellar region. In: Lloyd\u00a0RV (Hrsg) Surgical pathology of the pituitary gland. W.B. Saunders Company, Philadelphia, S\u00a0141\u2013210"},{"key":"932_CR62","first-page":"1","volume-title":"Pathologie der endokrinen Organe, Teil 2","author":"W Saeger","year":"1981","unstructured":"Saeger\u00a0W (1981) Hypophyse. In: Doerr\u00a0W, Seifert\u00a0G (Hrsg) Pathologie der endokrinen Organe, Teil 2. Springer, Berlin-Heidelberg-New York, S 1\u2013226"},{"key":"932_CR63","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1097\/00006123-199912000-00042","volume":"45","author":"T Beems","year":"1999","unstructured":"Beems\u00a0T, Grotenhuis\u00a0JA, Wesseling\u00a0P (1999) Meningioma of the pituitary stalk without dural attachment: case report and review of the literature. Neurosurgery 45:1474\u20131477","journal-title":"Neurosurgery"},{"key":"932_CR64","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1007\/s00292-019-00653-2","volume":"40","author":"C Mawrin","year":"2019","unstructured":"Mawrin\u00a0C (2019) Molekulare Biologie, Diagnostik und Therapie von Meningeomen. Pathologe 40:514\u2013518","journal-title":"Pathologe"},{"key":"932_CR65","first-page":"137","volume":"16","author":"C Madsen","year":"1997","unstructured":"Madsen\u00a0C, Schroder\u00a0HD (1997) Ki-67 immunoreactivity in meningiomas\u2014determination of the proliferation potential of meningiomas using the monclonal antibody Ki-67. Clin Neuropathol 16:137\u2013142","journal-title":"Clin. Neuropathol."},{"key":"932_CR66","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.clineuro.2015.06.001","volume":"137","author":"G Sharifi","year":"2015","unstructured":"Sharifi\u00a0G, Bakhtevari\u00a0MH, Alghasi\u00a0M, Saberi\u00a0M, Dehghan\u00a0M, Bidari\u00a0F, Rezaei\u00a0O (2015) Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature. Clin Neurol Neurosurg 137:38\u201343","journal-title":"Clin Neurol Neurosurg"},{"key":"932_CR67","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.5858\/2009-0476-OA.1","volume":"134","author":"NA Jambhekar","year":"2010","unstructured":"Jambhekar\u00a0NA, Rekhi\u00a0B, Thorat\u00a0K, Dikshit\u00a0R, Agrawal\u00a0M, Puri\u00a0A (2010) Revisiting Chordoma with Brachyury, a\u00a0\u201cnew Age\u201d marker analysis of a\u00a0validation study on 51 cases. Arch Pathol Lab Med 134:1181\u20131187","journal-title":"Arch Pathol Lab Med"},{"key":"932_CR68","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s12020-014-0184-3","volume":"47","author":"FF Jian","year":"2014","unstructured":"Jian\u00a0FF, Bian\u00a0LG, Sun\u00a0SY, Yang\u00a0J, Chen\u00a0X, Chen\u00a0YF, Ma\u00a0QY, Miao\u00a0F, Wang\u00a0WQ, Ning\u00a0G, Sun\u00a0QF (2014) Surgical biopsies in patients with central diabetes insipidus and thickened pituitary stalks. Endocrine 47:325\u2013335","journal-title":"Endocrine"},{"key":"932_CR69","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1023\/A:1009923029942","volume":"1","author":"M Fehn","year":"1999","unstructured":"Fehn\u00a0M, Bettendorf\u00a0M, L\u00fcdecke\u00a0DK, Sommer\u00a0C, Saeger\u00a0W (1999) Lymphocytic hypophysitis masking a\u00a0suprasellar germinoma in a\u00a012\u00a0year old girl\u2014a\u00a0case report. Pituitary 1:303\u2013307","journal-title":"Pituitary"},{"key":"932_CR70","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.wneu.2018.12.185","volume":"124","author":"JCM Low","year":"2019","unstructured":"Low\u00a0JCM, Maratos\u00a0E, Kumar\u00a0A, King\u00a0A, Al-Sarraj\u00a0S, Barazi\u00a0S (2019) Adult Parasellar capillary Hemangioma with Intrasellar extension. World Neurosurg 124:184\u2013191","journal-title":"World Neurosurg"},{"key":"932_CR71","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1159\/000224763","volume":"27","author":"K Kovacs","year":"1973","unstructured":"Kovacs\u00a0K (1973) Metastatic cancer of the pituitary gland. Oncology 27:533\u2013542","journal-title":"Oncology"},{"key":"932_CR72","first-page":"308","volume":"6","author":"W Saeger","year":"1985","unstructured":"Saeger\u00a0W, Riedel\u00a0M, Schr\u00f6der\u00a0H (1985) Metastasen in der Hypophyse und der Sella. Pathologe 6:308\u2013312","journal-title":"Pathologe"},{"key":"932_CR73","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/BF03345118","volume":"26","author":"P Viacava","year":"2003","unstructured":"Viacava\u00a0P, Gasperi\u00a0M, Acerbi\u00a0G, Manetti\u00a0L, Cecconi\u00a0E, Bonadio\u00a0AG, Naccarato\u00a0AG, Acerbi\u00a0F, Parenti\u00a0G, Lupi\u00a0I, Genovesi\u00a0M, Martino\u00a0E (2003) Microvascular density and vascular endothelial growth factor expression in normal pituitary tissue and pituitary adenomas. J\u00a0Endocrinol Invest 26:23\u201328","journal-title":"J Endocrinol Invest"},{"key":"932_CR74","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1177\/1066896912449478","volume":"21","author":"F Rotondo","year":"2013","unstructured":"Rotondo\u00a0F, Kovacs\u00a0K, Macdonald\u00a0RL, Prud\u2019homme\u00a0GJ, Latta\u00a0E, Munoz\u00a0D (2013) Non-small cell bronchial carcinoma metastasizing into a\u00a0Prolactin-producing pituitary Adenoma. Int J Surg Pathol 21:68\u201371","journal-title":"Int J Surg Pathol"},{"key":"932_CR75","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s004010051001","volume":"97","author":"W Paulus","year":"1999","unstructured":"Paulus\u00a0W, Honegger\u00a0J, Keyvani\u00a0K, Fahlbusch\u00a0R (1999) Xanthogranuloma of the sellar region: a\u00a0clinicopathological entity different from adamantinomatous craniopharyngioma. Acta Neuropathol 97:377\u2013382","journal-title":"Acta Neuropathol"},{"key":"932_CR76","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1365-2265.2011.04235.x","volume":"76","author":"R Trifanescu","year":"2012","unstructured":"Trifanescu\u00a0R, Ansorge\u00a0O, Wass\u00a0JAH, Grossman\u00a0AB, Karavitaki\u00a0N (2012) Rathke\u2019s cleft cysts. Clin Endocrinol 76:151\u2013160","journal-title":"Clin Endocrinol"},{"key":"932_CR77","doi-asserted-by":"crossref","first-page":"E4","DOI":"10.3171\/2010.2.FOCUS09318","volume":"28","author":"G Zada","year":"2010","unstructured":"Zada\u00a0G, Lin\u00a0N, Ojerholm\u00a0E, Ramkissoon\u00a0S, Laws\u00a0ER (2010) Craniopharyngioma and other cystic epithelial lesions of the sellar region: a\u00a0review of clinical, imaging, and histopathological relationships\u2014art. no. E4. Neurosurg Focus 28:E4","journal-title":"Neurosurg Focus"},{"key":"932_CR78","first-page":"263","volume":"15","author":"W Saeger","year":"2004","unstructured":"Saeger\u00a0W, L\u00fcdecke\u00a0DK, Buchfelder\u00a0M, Fahlbusch\u00a0R (2004) Metastases to the pituitary in surgical specimens. Endocr Pathol 15:263\u2013264","journal-title":"Endocr Pathol"}],"container-title":["Der Pathologe"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-021-00932-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00292-021-00932-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-021-00932-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T10:06:51Z","timestamp":1619690811000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00292-021-00932-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,20]]},"references-count":78,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["932"],"URL":"https:\/\/doi.org\/10.1007\/s00292-021-00932-x","relation":{},"ISSN":["0172-8113","1432-1963"],"issn-type":[{"type":"print","value":"0172-8113"},{"type":"electronic","value":"1432-1963"}],"subject":[],"published":{"date-parts":[[2021,4,20]]},"assertion":[{"value":"9 March 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2021","order":3,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":4,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Die Wissenschaftliche Leitung wurde korrigiert.","order":5,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"<b>W.\u00a0Saeger<\/b>: A.\u00a0Finanzielle Interessen: W.\u00a0Saeger gibt an, dass kein finanzieller Interessenkonflikt besteht.\u00a0\u2013 B.\u00a0Nichtfinanzielle Interessen: selbstst\u00e4ndiger Konsiliararzt f\u00fcr endokrine Pathologie, Universit\u00e4tsklinikum Hamburg-Eppendorf.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden vom Autor keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}