{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T14:41:34Z","timestamp":1651329694572},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathologe"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1007\/s00292-022-01067-3","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T15:03:37Z","timestamp":1649257417000},"page":"202-209","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epitheliale kindliche Lebertumoren"],"prefix":"10.1007","volume":"43","author":[{"given":"J. F.","family":"Lau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Vokuhl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"1067_CR1","unstructured":"Erdmann F, Grabow D, Kaatsch P, Spix C, Wellbrock M (2020) Jahresbericht 2019 des Deutschen Kinderkrebsregisters"},{"key":"1067_CR2","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/S0046-8177(83)80005-7","volume":"14","author":"AG Weinberg","year":"1983","unstructured":"Weinberg\u00a0AG, Finegold\u00a0MJ (1983) Primary hepatic tumors of childhood. Hum Pathol 14:512\u2013537","journal-title":"Hum Pathol"},{"key":"1067_CR3","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/S0022-3476(98)70008-3","volume":"132","author":"MR DeBaun","year":"1998","unstructured":"DeBaun\u00a0MR, Tucker\u00a0MA (1998) Risk of cancer during the first four years of life in children from the Beckwith-Wiedemann syndrome registry. J\u00a0Pediatr 132:398\u2013400","journal-title":"J Pediatr"},{"key":"1067_CR4","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/S0022-3476(05)80297-5","volume":"3","author":"FM Giardiello","year":"1991","unstructured":"Giardiello FM, Offerhaus JA, Krush AJ (1991) Risk of hepatoblastoma in familial adenomatous polyposis. J\u00a0Pediatr 3:766\u2013768","journal-title":"J\u00a0Pediatr"},{"key":"1067_CR5","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/j.jpeds.2009.06.039","volume":"155","author":"M Kato","year":"2009","unstructured":"Kato\u00a0M et\u00a0al (2009) Hepatoblastoma in a\u00a0patient with sotos syndrome. J\u00a0Pediatr 155:937\u2013939","journal-title":"J Pediatr"},{"key":"1067_CR6","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0022-3476(97)70239-7","volume":"130","author":"H Ikeda","year":"1997","unstructured":"Ikeda\u00a0H, Matsuyama\u00a0S, Tanimura\u00a0M (1997) Association between hepatoblastoma and very low birth weight: A trend or a\u00a0chance? J\u00a0Pediatr 130:557\u2013560","journal-title":"J Pediatr"},{"key":"1067_CR7","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1038\/modpathol.2013.80","volume":"27","author":"D L\u00f3pez-Terrada","year":"2014","unstructured":"L\u00f3pez-Terrada\u00a0D et al (2014) Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium. Mod Pathol 27:472\u2013491","journal-title":"Mod Pathol"},{"key":"1067_CR8","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1002\/1097-0142(19890901)64:5<1082::AID-CNCR2820640520>3.0.CO;2-G","volume":"64","author":"JE Haas","year":"1989","unstructured":"Haas\u00a0JE et\u00a0al (1989) Histopathology and prognosis in childhood hepatoblastoma and hepatocarcinoma. Cancer 64:1082\u20131095","journal-title":"Cancer"},{"key":"1067_CR9","doi-asserted-by":"publisher","first-page":"3301","DOI":"10.1200\/JCO.2010.29.3837","volume":"29","author":"MH Malogolowkin","year":"2011","unstructured":"Malogolowkin\u00a0MH et\u00a0al (2011) Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the children\u2019s oncology group. JCO 29:3301\u20133306","journal-title":"JCO"},{"key":"1067_CR10","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1177\/1093526619875228","volume":"23","author":"S Ranganathan","year":"2020","unstructured":"Ranganathan\u00a0S, Lopez-Terrada\u00a0D, Alaggio\u00a0R (2020) Hepatoblastoma and pediatric hepatocellular carcinoma: an update. Pediatr Dev Pathol 23:79\u201395","journal-title":"Pediatr Dev Pathol"},{"key":"1067_CR11","doi-asserted-by":"publisher","first-page":"00803","DOI":"10.1200\/JCO.21.00803","volume":"21","author":"A Trobaugh-Lotrario","year":"2021","unstructured":"Trobaugh-Lotrario\u00a0A et al (2021) Small cell undifferentiated histology does not adversely affect outcome in hepatoblastoma: a report from the children\u2019s oncology group (COG) AHEP0731 study committee. JCO 21:803. https:\/\/doi.org\/10.1200\/JCO.21.00803","journal-title":"JCO"},{"key":"1067_CR12","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1002\/gcc.22390","volume":"55","author":"C Vokuhl","year":"2016","unstructured":"Vokuhl\u00a0C et\u00a0al (2016) Small cell undifferentiated (SCUD) hepatoblastomas: All malignant rhabdoid tumors?: SCUD Hepatoblastomas. Genes Chromosomes Cancer 55:925\u2013931","journal-title":"Genes Chromosomes Cancer"},{"key":"1067_CR13","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3109\/15513818309048287","volume":"1","author":"J Rutledge","year":"1983","unstructured":"Rutledge\u00a0J, Beckwith\u00a0JB, Benjamin\u00a0D, Haas\u00a0JE (1983) Absence of immunoperoxidase staining for myoglobin in the malignant rhabdoid tumor of the kidney. Pediatr Pathol 1:93\u201398","journal-title":"Pediatr Pathol"},{"key":"1067_CR14","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1097\/00000478-200405000-00013","volume":"28","author":"AR Judkins","year":"2004","unstructured":"Judkins\u00a0AR, Mauger\u00a0J, Ht\u00a0A, Rorke\u00a0LB, Biegel\u00a0JA (2004) Immunohistochemical analysis of hSNF5\/INI1 in pediatric CNS neoplasms. Am J Surg Pathol 28:644\u2013650","journal-title":"Am J Surg Pathol"},{"key":"1067_CR15","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/28212","volume":"394","author":"I Versteege","year":"1998","unstructured":"Versteege\u00a0I et\u00a0al (1998) Truncating mutations of hSNF5\/INI1 in aggressive paediatric cancer. Nature 394:203\u2013206","journal-title":"Nature"},{"key":"1067_CR16","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1111\/neup.12452","volume":"38","author":"C Bookhout","year":"2018","unstructured":"Bookhout\u00a0C, Bouldin\u00a0TW, Ellison\u00a0DW (2018) Atypical teratoid\/rhabdoid tumor with retained INI1 (SMARCB1) expression and loss of BRG1 (SMARCA4): AT\/RT with retained INI1 and BRG1 loss. Neuropathology 38:305\u2013308","journal-title":"Neuropathology"},{"key":"1067_CR17","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1016\/j.jhep.2014.08.009","volume":"61","author":"M Eichenm\u00fcller","year":"2014","unstructured":"Eichenm\u00fcller\u00a0M et al (2014) The genomic landscape of hepatoblastoma and their progenies with HCC-like features. J\u00a0Hepatol 61:1312\u20131320","journal-title":"J Hepatol"},{"key":"1067_CR18","doi-asserted-by":"publisher","first-page":"4863","DOI":"10.1038\/sj.onc.1205591","volume":"21","author":"K Taniguchi","year":"2002","unstructured":"Taniguchi\u00a0K et al (2002) Mutational spectrum of \u03b2\u2011catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 21:4863\u20134871","journal-title":"Oncogene"},{"key":"1067_CR19","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.ejca.2020.09.026","volume":"141","author":"S Cairo","year":"2020","unstructured":"Cairo\u00a0S et\u00a0al (2020) A combined clinical and biological risk classification improves prediction of outcome in hepatoblastoma patients. Eur J Cancer 141:30\u201339","journal-title":"Eur J Cancer"},{"key":"1067_CR20","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1002\/mpo.10177","volume":"39","author":"A Prokurat","year":"2002","unstructured":"Prokurat\u00a0A et al (2002) Transitional liver cell tumors (TLCT) in older children and adolescents: A novel group of aggressive hepatic tumors expressing beta-catenin. Med Pediatr Oncol 39:510\u2013518","journal-title":"Med Pediatr Oncol"},{"key":"1067_CR21","doi-asserted-by":"publisher","first-page":"5423","DOI":"10.1038\/s41467-021-25430-9","volume":"12","author":"G Nagae","year":"2021","unstructured":"Nagae\u00a0G et\u00a0al (2021) Genetic and epigenetic basis of hepatoblastoma diversity. Nat Commun 12:5423","journal-title":"Nat Commun"},{"key":"1067_CR22","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1038\/ng.2256","volume":"44","author":"C Guichard","year":"2012","unstructured":"Guichard\u00a0C et al (2012) Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 44:694\u2013698","journal-title":"Nat Genet"},{"issue":"X","key":"1067_CR23","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1002\/hep.26540","volume":"58","author":"SP Cleary","year":"2013","unstructured":"Cleary\u00a0SP et\u00a0al (2013) Identification of driver genes in hepatocellular carcinoma by exome sequencing. Hepatology 58(X):1693\u20131702","journal-title":"Hepatology"},{"key":"1067_CR24","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1002\/cncr.11292","volume":"97","author":"HM Katzenstein","year":"2003","unstructured":"Katzenstein\u00a0HM et\u00a0al (2003) Fibrolamellar hepatocellular carcinoma in children and adolescents. Cancer 97:2006\u20132012","journal-title":"Cancer"},{"key":"1067_CR25","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1093\/carcin\/bgw118","volume":"38","author":"CV Rao","year":"2017","unstructured":"Rao\u00a0CV, Asch\u00a0AS, Yamada\u00a0HY (2017) Frequently mutated genes\/pathways and genomic instability as prevention targets in liver cancer. CARCIN 38:2\u201311","journal-title":"CARCIN"},{"key":"1067_CR26","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.clinre.2015.07.006","volume":"40","author":"J-C Nault","year":"2016","unstructured":"Nault\u00a0J\u2011C, Zucman-Rossi\u00a0J (2016) TERT promoter mutations in primary liver tumors. Clin Res Hepatol Gastroenterol 40:9\u201314","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"1067_CR27","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1053\/j.gastro.2014.12.028","volume":"148","author":"H Cornella","year":"2015","unstructured":"Cornella\u00a0H et\u00a0al (2015) Unique genomic profile of Fibrolamellar hepatocellular carcinoma. Gastroenterology 148:806\u2013818.e10","journal-title":"Gastroenterology"}],"container-title":["Der Pathologe"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-022-01067-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00292-022-01067-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00292-022-01067-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T08:07:41Z","timestamp":1651219661000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00292-022-01067-3"}},"subtitle":["Eine \u00dcbersicht der neuen WHO-Klassifikation f\u00fcr p\u00e4diatrische Tumoren"],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["1067"],"URL":"https:\/\/doi.org\/10.1007\/s00292-022-01067-3","relation":{},"ISSN":["0172-8113","1432-1963"],"issn-type":[{"value":"0172-8113","type":"print"},{"value":"1432-1963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,6]]},"assertion":[{"value":"24 February 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"J.F.\u00a0Lau und C.\u00a0Vokuhl geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}