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Ihre eindeutige Identifikation und Charakterisierung ist f\u00fcr betroffene Personen prognostisch und therapeutisch von gro\u00dfer Bedeutung. Ebenso wichtig ist aber auch die klare Abgrenzung anderer mesenchymaler Neoplasien, zu denen leiomyomat\u00f6se, neurogene, adipozyt\u00e4re und fibroblast\u00e4re Tumoren geh\u00f6ren. Zudem w\u00e4chst die Zahl der translokationspositiven Entit\u00e4ten, die sich nur mit entsprechenden molekularen Methoden eindeutig diagnostizieren lassen. Ziel dieses Beitrags ist es, f\u00fcr deren sichere Identifikation praktische Hinweise zu geben. 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