{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:43:36Z","timestamp":1740185016619,"version":"3.37.3"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T00:00:00Z","timestamp":1712793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T00:00:00Z","timestamp":1712793600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100012940","name":"Universit\u00e4tsklinikum T\u00fcbingen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012940","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathologie"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Wir stellen einen seltenen Fall mit h\u00e4matologischer Neoplasie bei einer jungen Erwachsenen vor, welche zuerst 2008 beschrieben wurde und seit 2022 in beide g\u00e4ngigen Tumorklassifikationssysteme h\u00e4matologischer Neoplasien, ICC und WHO, aufgenommen wurde. Diese Neoplasie zeigt eine charakteristische immunhisthochemische ALK-Positivit\u00e4t und entsprechend molekular ein ALK-Fusionsgen. Patholg*innen sollten diese Entit\u00e4t kennen, zumal eine Unterscheidung zwischen dieser Erkrankung und anderen h\u00e4ufiger auftretenden Erkrankungen des gleichen Formenkreises sowie einer mesenchymalen Neoplasie mit ALK-Aberration herausfordernd ist.<\/jats:p>","DOI":"10.1007\/s00292-024-01321-w","type":"journal-article","created":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T07:02:21Z","timestamp":1712818941000},"page":"284-289","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seltene Differenzialdiagnose bei osteolytischer L\u00e4sion des Unterkiefers einer jungen Erwachsenen","Rare differential diagnosis of an osteolytic lesion of the mandible in a young adult"],"prefix":"10.1007","volume":"45","author":[{"given":"Hyunkyu","family":"Shin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Naros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinja","family":"Kieninger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Polligkeit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Falko","family":"Fend","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5319-5677","authenticated-orcid":false,"given":"Jakob","family":"Milla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,11]]},"reference":[{"issue":"22","key":"1321_CR1","doi-asserted-by":"publisher","first-page":"2672","DOI":"10.1182\/blood-2016-01-690636","volume":"127","author":"Emile et al for the Histiocyte Society","year":"2016","unstructured":"Emile et\u00a0al for the Histiocyte Society (2016) Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. 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Blood 112(7):2965\u20132968. https:\/\/doi.org\/10.1182\/blood-2008-03-147017","journal-title":"Blood"},{"issue":"2","key":"1321_CR4","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1182\/blood.2021013338","volume":"139","author":"Kemps","year":"2022","unstructured":"Kemps et\u00a0al (2022) ALK-positive histiocytosis: a\u00a0new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition. Blood 139(2):256\u2013280. https:\/\/doi.org\/10.1182\/blood.2021013338","journal-title":"Blood"},{"key":"1321_CR5","doi-asserted-by":"publisher","first-page":"e30010","DOI":"10.1002\/pbc.30010","volume":"70","author":"Wang","year":"2023","unstructured":"Wang et\u00a0al (2023) Anaplastic lymphoma kinase positive histiocytosis presenting as hemocytopenia in an infant. Pediatr Blood Cancer 70:e30010. https:\/\/doi.org\/10.1002\/pbc.30010","journal-title":"Pediatr Blood Cancer"},{"key":"1321_CR6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/his.14569","volume":"80","author":"S Fraitag","year":"2022","unstructured":"Fraitag\u00a0S, Emile\u00a0JF (2022) Cutaneous histiocytoses in children. Histopathology 80:196\u2013215. https:\/\/doi.org\/10.1111\/his.14569","journal-title":"Histopathology"},{"issue":"5","key":"1321_CR7","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1038\/s41379-018-0168-6","volume":"32","author":"Chang","year":"2019","unstructured":"Chang et\u00a0al (2019) ALK-positive histiocytosis: an expanded clinicopathologic spectrum and frequent presence of KIF5B-ALKfusion. Mod Pathol 32(5):598\u2013608. https:\/\/doi.org\/10.1038\/s41379-018-0168-6","journal-title":"Mod Pathol"},{"key":"1321_CR8","unstructured":"WHO WHO classification of tumours editorial board. Haematolymphoid tumours. WHO classification of tumours series, 5th\u00a0ed.; vol.\u00a011. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}