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In diesem \u00dcbersichtsbeitrag, der im Rahmen der Fachsitzung der AG Kinderpathologie gehalten wurde, gibt der Autor einen Einblick in die histopathologische Diagnostik des Morbus Hirschsprung inklusive der technischen Herangehensweise an die Biopsien. Daneben stellt der Autor verschiedene Differentialdiagnosen der chronischen intestinalen Pseudoobstruktion (CIPO) vor, zu deren Erkennung die histopathologische Diagnostik beitragen kann. 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