{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T09:48:27Z","timestamp":1761126507794},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2006,6,24]],"date-time":"2006-06-24T00:00:00Z","timestamp":1151107200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2006,9]]},"DOI":"10.1007\/s00296-006-0148-x","type":"journal-article","created":{"date-parts":[[2006,6,23]],"date-time":"2006-06-23T13:21:44Z","timestamp":1151068904000},"page":"953-958","source":"Crossref","is-referenced-by-count":10,"title":["The treatment of the rheumatological manifestations of the inflammatory bowel diseases"],"prefix":"10.1007","volume":"26","author":[{"given":"Melissa","family":"Padovan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Castellino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Govoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Trotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,6,24]]},"reference":[{"key":"148_CR1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1136\/gut.42.3.387","volume":"42","author":"TR Orchard","year":"1998","unstructured":"Orchard TR, Wordsworth BP, Jewell DP (1998) Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history. Gut 42:387\u2013391","journal-title":"Gut"},{"key":"148_CR2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0889-857X(05)70042-9","volume":"24","author":"F Keyser De","year":"1998","unstructured":"De Keyser F, Elewaut D, De Vos M, De Vlam K, Cuvelier C, Mielants H, Veys EM (1998) Bowel inflammation and the spondyloarthropathies. Rheum Dis Clin North Am 24:785\u2013813","journal-title":"Rheum Dis Clin North Am"},{"key":"148_CR3","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0889-857X(03)00043-7","volume":"29","author":"W Holden","year":"2003","unstructured":"Holden W, Orchard T, Wordsworth P (2003) Enteropathic arthritis. Rheum Dis Clin North Am 29:513\u2013530","journal-title":"Rheum Dis Clin North Am"},{"issue":"Suppl 2","key":"148_CR4","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/rheumatology\/XXVII.suppl_2.95","volume":"27","author":"H Mielants","year":"1988","unstructured":"Mielants H, Veys EM, Cuvelier C, de Vos M (1988) Ileocolonscopic findings in seronegative spondyloarthropathies. Br J Rheumatol 27(Suppl 2):95\u2013105","journal-title":"Br J Rheumatol"},{"key":"148_CR5","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1053\/berh.2002.0249","volume":"16","author":"D Baeten","year":"2002","unstructured":"Baeten D, De Keyser F, Mielants H, Veys EM (2002) Ankylosing spondylitis and bowel disease. Best Pract Res Clin Rheumatol 16:537\u2013549","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"148_CR6","first-page":"2279","volume":"22","author":"H Mielants","year":"1995","unstructured":"Mielants H, Veys EM, Cuvelier C, de Vos M, Goemaere S, De Clercq L, Schotteman L, Elewaut D (1995) The evolution of spondyloarthropathies in relation to gut histology. Part: III relation between gut and joint. J Rheumatol 22:2279\u20132284","journal-title":"J Rheumatol"},{"key":"148_CR7","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1097\/00002281-200207000-00002","volume":"14","author":"D Baeten","year":"2002","unstructured":"Baeten D, De Keyser F, Mielants H, Veys EM (2002) Immune linkages between inflammatory bowel disease and spondyloarthropathies. Curr Opin Rheumatol 14:342\u2013347","journal-title":"Curr Opin Rheumatol"},{"key":"148_CR8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1136\/ard.62.3.215","volume":"62","author":"A Tubergen van","year":"2003","unstructured":"van Tubergen A, van der Heijde D, Anderson J, Landew\u00e9 R, Dougados M, Braun J, Bellamy N, Udrea G, van der Linden S (2003) Comparison of statistically derived ASAS improvement criteria for ankylosing spondylitis with clinically relevant improvement according to an expert panel. Ann Rheum Dis 62:215\u2013221","journal-title":"Ann Rheum Dis"},{"key":"148_CR9","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1136\/ard.2003.014589","volume":"63","author":"N Barkham","year":"2004","unstructured":"Barkham N, Marzo-Ortega H, McGonagle D, Emery P (2004) How to diagnose axial spondyloarthropathy early. Ann Rheum Dis 63:471\u2013472","journal-title":"Ann Rheum Dis"},{"key":"148_CR10","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1002\/1529-0131(200112)44:12<2728::AID-ART459>3.0.CO;2-8","volume":"44","author":"S Smale","year":"2001","unstructured":"Smale S, Natt RS, Orchard TR, Russell AS, Bjarnason I (2001) Inflammatory bowel disease and spondyloarthropathy. Arthritis Rheum 44:2728\u20132736","journal-title":"Arthritis Rheum"},{"key":"148_CR11","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/1529-0131(199908)12:4<247::AID-ART3>3.0.CO;2-H","volume":"12","author":"MM Ward","year":"1999","unstructured":"Ward MM (1999) Health-related quality of life in ankylosing spondylitis: survey of 175 patients. Arthritis Care Res 12:247\u2013255","journal-title":"Arthritis Care Res"},{"key":"148_CR12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/art1.10179","volume":"47","author":"A Tubergen van","year":"2002","unstructured":"van Tubergen A, CoenenJ, Landew\u00e9 R, Spoorenberg A, Chorus A, Boonen A, van der Linder S, van der Heijde D (2002) Assessment of fatigue in patients with ankylosing spondylitis. A psychometric analysis. Arthrtis Care Res 47:8\u201316","journal-title":"Arthrtis Care Res"},{"key":"148_CR13","first-page":"208","volume-title":"Inflammatory bowel diseases: pathophysiology as basis of treatment","author":"I Bjarnason","year":"1993","unstructured":"Bjarnason I, Macpherson AJS, Somasundaram S, Teahon K (1993) Non-steroidal anti-inflammatory drugs and Crohn\u2019s disease. In: Scholmeric J, Kruis W, Goebbell H, Hoenberger W, Gross V (eds) Inflammatory bowel diseases: pathophysiology as basis of treatment. Kluwer, Lancaster, pp 208\u2013222"},{"key":"148_CR14","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1016\/0016-5085(93)90667-2","volume":"104","author":"I Bjarnason","year":"1993","unstructured":"Bjarnason I, Hayllar J, Macpherson AJ, Russell AS (1993) Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine. Gastroenterology 104:1832\u20131847","journal-title":"Gastroenterology"},{"key":"148_CR15","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/pgmj.57.667.297","volume":"57","author":"DS Rampton","year":"1981","unstructured":"Rampton DS, Sladen GE (1981) Relapse of ulcerative proctocolitis during treatment with NSAIDs. Postgrad Med J 57:297\u2013299","journal-title":"Postgrad Med J"},{"key":"148_CR16","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/gut.31.2.179","volume":"31","author":"SA Riley","year":"1990","unstructured":"Riley SA, Mani V, Goodman MJ, Lucas S (1990) Why do patients with ulcerative colitis relapse? Gut 31:179\u2013183","journal-title":"Gut"},{"key":"148_CR17","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/j.1365-2036.2004.01907.x","volume":"19","author":"L Biancone","year":"2004","unstructured":"Biancone L, Tosti C, Geremia A, Fina D, Petruzziello C, Emerenziani S, Pallone F (2004) Rofecoxib and early relapse of inflammatory bowel disease: an open-label trial. Aliment Pharmacol Ther 19:755\u2013764","journal-title":"Aliment Pharmacol Ther"},{"key":"148_CR18","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/1529-0131(200110)45:5<430::AID-ART362>3.0.CO;2-F","volume":"45","author":"A Tubergen Van","year":"2001","unstructured":"Van Tubergen A, Landew\u00e9 R, van der Heijde D, Hidding A, Wolter N, Asscher M, Falkenbach A, Genth E, The HG, van der Linden S (2001) Combined Spa-exercise therapy is effective in patients with ankylosing spondylitis: a randomized controlled trial. Arthritis Care Res 45:430\u2013438","journal-title":"Arthritis Care Res"},{"key":"148_CR19","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/art.1780380507","volume":"38","author":"M Dougados","year":"1995","unstructured":"Dougados M, van der Linden S, Lerislao-Repo M, Hutfeldt B, Juhlin R, Veys E, Zeidler H, Kuien TK, Olivieri I, Dijkmans B et al (1995) Sulfasalazine in the treatment of spondyloarthropathy. A randomised, multicenter, double-blind, placebo-controlled study. Arthritis Rheum 38:618\u2013627","journal-title":"Arthritis Rheum"},{"key":"148_CR20","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1002\/art.1780391209","volume":"39","author":"DO Clegg","year":"1996","unstructured":"Clegg DO, Reda DJ, Weisman MH, Cush JJ, Vasey FB, Schumacher HR Jr, Budiman-Mak E, Balestra DJ, Blackburn WD, Cannon GW, Inman RD, Alepa FP, Mejias E, Cohen MR, Makkena R, Mahowald ML, Higashida J, Silverman SL, Parhami N, Buxbaum J, Haakenson CM, Ward RH, Manaster BJ, Anderson RJ, Henderson WG et al (1996) Comparison of sulfasalazine and placebo in the treatment of ankylosing spondylitis. Arthritis Rheum 39:2004\u20132012","journal-title":"Arthritis Rheum"},{"key":"148_CR21","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1002\/art.1780390819","volume":"39","author":"AG Taggart","year":"1996","unstructured":"Taggart AG, Gardiner P, McEvoy FM, Hopkins R, Bird H (1996) Which is the active moiety of sulfasalazine in ankylosing spondylitis? A randomised controlled study. Arthritis Rheum 39:1400\u20131405","journal-title":"Arthritis Rheum"},{"key":"148_CR22","first-page":"570","volume":"21","author":"GT Thomson","year":"1994","unstructured":"Thomson GT, McKibbon C, Inman RD (1994) Mesalamine therapy in Reiter\u2019s syndrome. J Rheumatol 21:570\u2013572","journal-title":"J Rheumatol"},{"key":"148_CR23","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s000110050558","volume":"49","author":"F Keyser De","year":"2000","unstructured":"De Keyser F, Van Damme N, De Vos M, Mielants H, Veys EM (2000) Opportunities for immune modulation in the spondyloarthropathies with special reference to gut inflammation. Inflamm Res 49:47\u201354","journal-title":"Inflamm Res"},{"key":"148_CR24","unstructured":"Chen J, LC (2004) Methotrexate for ankylosing-spondylitis. Cochrane Database Syst Rev (3):CD004524"},{"key":"148_CR25","first-page":"1568","volume":"31","author":"L Gonzales-Lopez","year":"2004","unstructured":"Gonzales-Lopez L, Garcia-Gonzalez A, Vasquez-Del Mercado M, Munoz-Valle JF, Gamez-Nava JI (2004) Efficacy of methotrexate in ankylosing spondylitis. J Rheumatol 31:1568\u20131574","journal-title":"J Rheumatol"},{"key":"148_CR26","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1136\/ard.2003.019174","volume":"64","author":"H Haibel","year":"2005","unstructured":"Haibel H, Rudwaleit M, Braun J, Sieper J (2005) Six months open label trial of leflunomide in active ankylosing spondylitis. Ann Rheum Dis 64:124\u2013126","journal-title":"Ann Rheum Dis"},{"key":"148_CR27","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s100670050027","volume":"19","author":"D Biasi","year":"2000","unstructured":"Biasi D, Carletto A, Caramaschi P, Pacor ML Maleknia T, Bambara LM (2000) Efficacy of methotrexate in the treatment of ankylosing spondylitis: a three-year open study. Clin Rheumatol 19:114\u2013117","journal-title":"Clin Rheumatol"},{"key":"148_CR28","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s000110050558","volume":"49","author":"F Keyser De","year":"2000","unstructured":"De Keyser F, Van Damme N, De Vos M, Mielants H, Veys EM (2000) Opportunities for immune modulation in the spondyloarthropathies with special reference to gut inflammation. Inflamm Res 49:47\u201354","journal-title":"Inflamm Res"},{"key":"148_CR29","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1002\/art.10139","volume":"46","author":"WP Maksymowych","year":"2002","unstructured":"Maksymowych WP, Jhangri GS, Fitzgerald AA, LeClercq S, Chiu P, Yan A, Skeith KJ, Aaron SL, Homik J, Davis P, Sholter D, Russell AS (2002) A six-month randomized, controlled, double-blind, dose-response comparison of intravenous pamidronate (60\u00a0mg versus 10\u00a0mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis. Arthritis Rheum 46:766\u2013773","journal-title":"Arthritis Rheum"},{"key":"148_CR30","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/art.10396","volume":"47","author":"F Huang","year":"2002","unstructured":"Huang F, Gu J, Zhao W, Zhu J, Zhang J, Yu DT (2002) One-year open-label trial of thalidomide in ankylosing spondylitis. Arthritis Rheum 47:249\u2013254","journal-title":"Arthritis Rheum"},{"key":"148_CR31","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1136\/ard.59.2.135","volume":"59","author":"M Bollow","year":"2000","unstructured":"Bollow M, Fisher T, Reisshauer H, Backhaus M, Sieper J, Hamm B, Braun J (2000) Quantitative analyse of sacroiliac biopsies in spondyloarthropathies: T cells and macrophages predominate in early and active sacroiliitis as detected by magnetic resonance imaging in spondyloarthropathies. Ann Rheum Dis 59:135\u2013140","journal-title":"Ann Rheum Dis"},{"key":"148_CR32","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/PL00000223","volume":"50","author":"G McCormack","year":"2001","unstructured":"McCormack G, Moriarty D, O\u2019Donoghue DP, McCormick PA, Sheahan K, Baird AW (2001) Tissue cytokine and chemokine expression in inflammatory boweldisease. Inflamm Res 50:491\u2013495","journal-title":"Inflamm Res"},{"key":"148_CR33","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/S0140-6736(02)08215-6","volume":"359","author":"J Braun","year":"2002","unstructured":"Braun J, Brandt J, Listing J, Zink A, Alten R, Golder W, Gromnica-Ihle E, Kellner H, Krause A, Schneider M, Sorensen H, Zeidler H, Thriene W, Sieper J (2002) Treatment of active ankylosing spondylitis with infliximab: a double blind placebo controlled multicenter trial. Lancet 359:1187\u20131193","journal-title":"Lancet"},{"key":"148_CR34","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1056\/NEJMoa012664","volume":"346","author":"JD Gorman","year":"2002","unstructured":"Gorman JD, Sack KE, Davis JC (2002) Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor \u03b1. New Engl J Med 346:1349\u20131356","journal-title":"New Engl J Med"},{"key":"148_CR35","doi-asserted-by":"crossref","first-page":"3230","DOI":"10.1002\/art.11325","volume":"48","author":"JC Davis","year":"2003","unstructured":"Davis JC, van der Hejide D, Braun J, Dougados M, Cush J, Clegg DO, Kivitz A, Fleischmann R, Inman R, Tsuji W (2003) Recombinant human tumor necrosis factor receptor (Etanercept) for treating ankylosing spondylitis. Arthritis Rheum 48:3230\u20133236","journal-title":"Arthritis Rheum"},{"key":"148_CR36","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1002\/art.11104","volume":"48","author":"J Braun","year":"2003","unstructured":"Braun J, Brandt J, Listing J, Zink A, Alten R, Baumester G, Golder W, Gromnica-Ihle E, Kellner H, Schneider M, Sorensen H, Zeidler H, Reddig J, Sieper J (2003) Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis. Arthritis Rheum 48:2224\u20132233","journal-title":"Arthritis Rheum"},{"key":"148_CR37","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1136\/ard.2004.020875","volume":"63","author":"A Calin","year":"2004","unstructured":"Calin A, Dijkmans BA, Emery P, Hakala M, Kalden J, Leirisalo-Repo M, Mola EM, Salvarani C, Sanmarti R, Sany J, Sibilia J, Sieper J, van der Linden S, Veys E, Appel AM, Fatenejad S (2004) Outcomes of multicenter randomizes clinical trial of etanercept to treat ankylosing spondylitis. Ann Rheum Dis 63:1594\u20131600","journal-title":"Ann Rheum Dis"},{"key":"148_CR38","first-page":"82","volume":"52","author":"D Heijde Van der","year":"2004","unstructured":"Van der Heijde D, Dijkmans BA, Geusens P, Sieper J, DeWoody K, Williamson P, Braun J (2004) Efficacy and safety of infliximab in patients with ankylosing spondylitis: result of a 23-week randomized, placebo controlled trial (ASSERT). Ann Rheum Dis 52:82\u2013591","journal-title":"Ann Rheum Dis"},{"key":"148_CR39","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1016\/S0140-6736(00)03239-6","volume":"356","author":"F Bosch van den","year":"2000","unstructured":"van den Bosch F, Kruithof E, De Vos M, De Keyser F, Mielants H (2000) Crohn\u2019s disease associated with spondyloarthropathy: effect of TNF-\u03b1 blockade with infliximab on articular symptoms. Lancet 356:1821\u20131822","journal-title":"Lancet"},{"key":"148_CR40","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00124743-200104000-00002","volume":"7","author":"MH Ellman","year":"2001","unstructured":"Ellman MH, Hanauer S, Sitrin M, Cohen R (2001) Crohn\u2019s disease arthritis treated with infliximab: an open trial in four patients. J Clin Rheumatol 7:67\u201371","journal-title":"J Clin Rheumatol"},{"key":"148_CR41","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1136\/ard.62.1.74","volume":"62","author":"H Marzo-Ortega","year":"2003","unstructured":"Marzo-Ortega H, McGonagle D, O\u2019Connor P, Emery P (2003) Efficacy of etanercept for treatment of Crohn\u2019s related spondyloarthritis but not colitis. Ann Rheum Dis 62:74\u201376","journal-title":"Ann Rheum Dis"},{"key":"148_CR42","first-page":"63","volume":"12","author":"I Kaufman","year":"2004","unstructured":"Kaufman I, Caspi D, Yeshurun D, Dotan I, Yaron M, Elkayam O (2004) The effect of infliximab on extraintestinal manifestations of Crohn\u2019s disease. Rheumatol Int 12:63\u201366","journal-title":"Rheumatol Int"},{"key":"148_CR43","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1136\/ard.2003.012450","volume":"63","author":"S Generini","year":"2004","unstructured":"Generini S, Giacomelli R, Fedi R, Fulminis A, Pignone A, Frieri G, Del Rosso A, Viscido A, Galletti B, Fazzi M, Tonelli F, Matucci-Cerinic M (2004) Infliximab in spondyloarthropathy associated with Crohn\u2019s disease: an open study on the efficacy in inducing and maintaining remission of musculoskeletal and gut manifestations. Ann Rheum Dis 63:1664\u20131669","journal-title":"Ann Rheum Dis"},{"key":"148_CR44","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1053\/j.gastro.2005.03.003","volume":"128","author":"G Jarnerot","year":"2005","unstructured":"Jarnerot G, Hertervig, Friis-Liby I, Blomquist L, Karlen P, Granno C, Vilien M, Strom M, Danielsson A, Verbaan H, Hellstrom PM, Magnuson A, Curman B (2005) Infliximab as rescue therapy in severe to moderate ulcerative colitis: a randomised, placebo-controlled study. Gastroenterology 128:1805\u20131811","journal-title":"Gastroenterology"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-006-0148-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-006-0148-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-006-0148-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T11:16:03Z","timestamp":1559042163000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-006-0148-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,24]]},"references-count":44,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["148"],"URL":"https:\/\/doi.org\/10.1007\/s00296-006-0148-x","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,24]]}}}