{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:58:41Z","timestamp":1787165921444,"version":"build-2736575974"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T00:00:00Z","timestamp":1315440000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1007\/s00296-011-2109-2","type":"journal-article","created":{"date-parts":[[2011,9,7]],"date-time":"2011-09-07T07:52:29Z","timestamp":1315381949000},"page":"3039-3045","source":"Crossref","is-referenced-by-count":85,"title":["Scleroderma pattern of nailfold capillary changes as predictive value for the development of a connective tissue disease: a follow-up study of 3,029 patients with primary Raynaud\u2019s phenomenon"],"prefix":"10.1007","volume":"32","author":[{"given":"Slavica","family":"Pavlov-Dolijanovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nemanja S.","family":"Damjanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roksanda M.","family":"Stojanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada Z.","family":"Vujasinovic Stupar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejana M.","family":"Stanisavljevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,9,8]]},"reference":[{"key":"2109_CR1","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1056\/NEJMcp013013","volume":"347","author":"FM Wigley","year":"2002","unstructured":"Wigley FM (2002) Raynaud\u2019s phenomenon. N Engl J Med 347:1001\u20131008","journal-title":"N Engl J Med"},{"key":"2109_CR2","first-page":"289","volume":"9","author":"HR Maricq","year":"1982","unstructured":"Maricq HR, Weinberg AB, LeRoy EC (1982) Early detection of scleroderma-spectrum disorders by in vivo capillary microscopy: a prospective study of patients with Raynaud\u2019s phenomenon. J Rheumatol 9:289\u2013291","journal-title":"J Rheumatol"},{"key":"2109_CR3","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1136\/ard.41.4.382","volume":"41","author":"CG Kallenberg","year":"1982","unstructured":"Kallenberg CG, Pastoor GW, Wouda AA (1982) Antinuclear antibodies in patients with Raynaud\u2019s phenomenon: clinical significance of anticentromere antibodies. Ann Rheum Dis 41:382\u2013387","journal-title":"Ann Rheum Dis"},{"key":"2109_CR4","first-page":"756","volume":"80","author":"JM Porter","year":"1976","unstructured":"Porter JM, Bardana EJ Jr, Baur GM, Wesche DH, Andrasch RH, Rosch J (1976) The clinical significance of Raynaud\u2019s syndrome. Surgery 80:756\u2013764","journal-title":"Surgery"},{"key":"2109_CR5","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/BF02283115","volume":"11","author":"P Zufferey","year":"1992","unstructured":"Zufferey P, Depairon M, Chamot AM, Monti M (1992) Prognostic significance of nailfold capillary microscopy in patients with Raynaud\u2019s phenomenon and scleroderma pattern abnormalities: a six-years follow-up study. Clin Rheumatol 11:536\u2013541","journal-title":"Clin Rheumatol"},{"key":"2109_CR6","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1001\/archinte.158.6.595","volume":"158","author":"G Spencer-Green","year":"1998","unstructured":"Spencer-Green G (1998) Outcomes in primary Raynaud phenomenon: a meta-analysis of the frequency, rates, and predictors of transition to secondary diseases. Arch Intern Med 158:595\u2013600","journal-title":"Arch Intern Med"},{"key":"2109_CR7","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1002\/art.11310","volume":"48","author":"M Cutolo","year":"2003","unstructured":"Cutolo M, Grassi W, Matucci Cerinic M (2003) Raynaud\u2019s phenomenon and the role of capillaroscopy. Arthr Rheum 48:3023\u20133030","journal-title":"Arthr Rheum"},{"key":"2109_CR8","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/0002-9343(76)90410-1","volume":"61","author":"HR Maricq","year":"1976","unstructured":"Maricq HR, Spencer-Green G, LeRoy EC (1976) Skin capillary abnormalities as indicators of organ involvement in scleroderma (systemic sclerosis), Raynaud syndrome and dermatomyositis. Am J Med 61:862\u2013870","journal-title":"Am J Med"},{"key":"2109_CR9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/art.1780230208","volume":"23","author":"HR Maricq","year":"1980","unstructured":"Maricq HR, LeRoy EC, D\u2019Angelo WA et al (1980) Diagnostic potential of in vivo capillary microscopy in scleroderma and related disorders. Arthr Rheum 23:183\u2013189","journal-title":"Arthr Rheum"},{"key":"2109_CR10","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1136\/ard.44.9.603","volume":"44","author":"PM Houtman","year":"1985","unstructured":"Houtman PM, Kallenberg CGM, Wouda AA, The TH (1985) Decreased nailfold capillary density in Raynaud phenomenon: a reflection of immunologically mediated local and systemic vascular disease. Ann Rheum Dis 44:603\u2013609","journal-title":"Ann Rheum Dis"},{"key":"2109_CR11","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10067-005-1146-1","volume":"25","author":"M Meli","year":"2006","unstructured":"Meli M, Gityelmann G, Koppensteiner R, Amann-Vesti BR (2006) Predictive value of nailfold capillaroscopy in patients with Raynaud\u2019s phenomenon. Clin Rheumatol 25:153\u2013158","journal-title":"Clin Rheumatol"},{"key":"2109_CR12","first-page":"485","volume":"10","author":"EC LeRoy","year":"1992","unstructured":"LeRoy EC, Medsger TA Jr (1992) Raynaud\u2019s phenomenon: a proposal for classification. Clin Exp Rheumatol 10:485\u2013488","journal-title":"Clin Exp Rheumatol"},{"key":"2109_CR13","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/art.1780240907","volume":"24","author":"HR Maricq","year":"1981","unstructured":"Maricq HR (1981) Widefield capillary microscopy: technique and rating scale for abnormalities seen in scleroderma and related disorders. Arthr Rheum 24:1159\u20131164","journal-title":"Arthr Rheum"},{"key":"2109_CR14","first-page":"12","volume":"28","author":"N Damjanov","year":"1998","unstructured":"Damjanov N, Pavlov S, Radosavljevic V, Ostojic P, Curcic A (1998) Prognostic significance of capillaroscopic findings in subjects with Raynaud phenomenon. Acta Rheumatol Belgradensia 28:12\u201317","journal-title":"Acta Rheumatol Belgradensia"},{"key":"2109_CR15","first-page":"202","volume":"15","author":"EC LeRoy","year":"1988","unstructured":"LeRoy EC, Black C, Fleischmajer R et al (1988) Scleroderma (systemic sclerosis): classification, subset and pathogenesis. J Rheumatol 15:202\u2013205","journal-title":"J Rheumatol"},{"key":"2109_CR16","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/art.1780251101","volume":"25","author":"EM Tan","year":"1982","unstructured":"Tan EM, Cohen AS, Fries JF et al (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthr Rheum 25:1271\u20131277","journal-title":"Arthr Rheum"},{"key":"2109_CR17","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","volume":"31","author":"FC Arnett","year":"1988","unstructured":"Arnett FC, Edworthy SM, Bloch DA et al (1988) The American Rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthr Rheum 31:315\u2013324","journal-title":"Arthr Rheum"},{"key":"2109_CR18","first-page":"328","volume":"16","author":"D Alarcon-Segovia","year":"1989","unstructured":"Alarcon-Segovia D, Cardiel MH (1989) Comparison between 3 diagnostic criteria for mixed connective tissue disease. Study of 593 patients. J Rheumatol 16:328\u2013334","journal-title":"J Rheumatol"},{"key":"2109_CR19","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM197502202920807","volume":"292","author":"A Bohan","year":"1975","unstructured":"Bohan A, Peter JB (1975) Polymyositis and dermatomyositis (second of two parts). N Engl J Med 292:403\u2013407","journal-title":"N Engl J Med"},{"key":"2109_CR20","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1136\/ard.61.6.554","volume":"61","author":"C Vitali","year":"2002","unstructured":"Vitali C, Bombardieri S, Jonsson R et al (2002) Classification criteria for Sj\u00f6gren\u2019s syndrome: a revised version of the European criteria proposed by the American-Europe Consensus Group. Ann Rheum Dis 61:554\u2013558","journal-title":"Ann Rheum Dis"},{"key":"2109_CR21","first-page":"615","volume":"17","author":"M Mosca","year":"1999","unstructured":"Mosca M, Neri R, Bombardieri S (1999) Undifferentiated connective tissue diseases (UCTD): a review of the literature and a proposal for preliminary classification criteria. Clin Exp Rheum 17:615\u2013620","journal-title":"Clin Exp Rheum"},{"key":"2109_CR22","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1002\/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F","volume":"42","author":"WA Wilson","year":"1999","unstructured":"Wilson WA, Gharavi AE, Koike T et al (1999) International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthr Rheum 42:1309\u20131311","journal-title":"Arthr Rheum"},{"key":"2109_CR23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/sim.4780130513","volume":"13","author":"G Campbell","year":"1994","unstructured":"Campbell G (1994) Advances in statistical methodology for the evaluation of diagnosis and laboratory test. Stat Med 13:499\u2013508","journal-title":"Stat Med"},{"key":"2109_CR24","first-page":"111","volume":"25","author":"C Cervini","year":"1996","unstructured":"Cervini C, Grassi W (1996) Raynaud\u2019s phenomenon. Rheumatol Eur 25:111\u2013113","journal-title":"Rheumatol Eur"},{"key":"2109_CR25","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0021-9681(86)90109-8","volume":"39","author":"HR Maricq","year":"1986","unstructured":"Maricq HR, Weinrich MC, Keli JE, LeRoy EC (1986) Prevalence of Raynaud\u2019s phenomenon in the general population. J Chron Dis 39:423\u2013427","journal-title":"J Chron Dis"},{"key":"2109_CR26","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0002-9343(82)90846-4","volume":"72","author":"FE Harper","year":"1982","unstructured":"Harper FE, Maricq HR, Turner RE, Lidman RW, LeRoy EC (1982) A prospective study of Raynaud phenomenon and early connective tissue disease. A five-year report. Am J Med 72:883\u2013888","journal-title":"Am J Med"},{"key":"2109_CR27","first-page":"62","volume":"18","author":"Z Nagy","year":"2004","unstructured":"Nagy Z, Czirj\u00e1k L (2004) Nailfold digital capillaroscopy in 447 patients with connective tissue disease and Raynaud\u2019s disease. JEADV 18:62\u201368","journal-title":"JEADV"},{"key":"2109_CR28","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/ard.55.8.507","volume":"55","author":"Y Kabasakal","year":"1996","unstructured":"Kabasakal Y, Elvins DM, Ring EF, McHugh NJ (1996) Quantitative nailfold capillaroscopy findings in a population with connective tissue disease and in normal healthy controls. Ann Rheum Dis 55:507\u2013512","journal-title":"Ann Rheum Dis"},{"key":"2109_CR29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1191\/0961203302lu144oa","volume":"11","author":"RNV Furtado","year":"2002","unstructured":"Furtado RNV, Pucinelli ML, Cristo VV, Andrade LE, Sato EI (2002) Scleroderma like nailfold capillaroscopic abnormalities are associated with anti-U1-RNP antibodies and Raynaud\u2019s phenomenon in SEL patients. Lupus 11:35\u201341","journal-title":"Lupus"},{"key":"2109_CR30","first-page":"1403","volume":"27","author":"M Nakano","year":"2000","unstructured":"Nakano M, Ohuchi Y, Hasegawa H, Kuroda T, Ito S, Gejyo F (2000) Clinical significance of anticentromere antibodies in patients with systemic lupus erythematosus. J Rheumatol 27:1403\u20131407","journal-title":"J Rheumatol"},{"key":"2109_CR31","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/0002-9343(80)90462-3","volume":"69","author":"MJ Fritzler","year":"1980","unstructured":"Fritzler MJ, Kinsella TD (1980) The CREST syndrome: a distinct serologic entirety with anticentromere antibodies. Am J Med 69:520\u2013526","journal-title":"Am J Med"},{"key":"2109_CR32","first-page":"1826","volume":"18","author":"C Ferri","year":"1991","unstructured":"Ferri C, Bernini L, Cecchetti R et al (1991) Cutaneous and serologic subset of systemic sclerosis. J Rheumatol 18:1826\u20131832","journal-title":"J Rheumatol"},{"key":"2109_CR33","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/0002-9343(87)90647-4","volume":"83","author":"J Sarkozi","year":"1987","unstructured":"Sarkozi J, Bookman AM, Lee P, Keystone EC, Fritzler MJ (1987) Significance of anticentromere antibody in idiopathic Raynaud\u2019s syndrome. Am J Med 83:893\u2013898","journal-title":"Am J Med"},{"key":"2109_CR34","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s00296-009-1019-z","volume":"29","author":"SN Lambova","year":"2009","unstructured":"Lambova SN, M\u00fcller-Ladner U (2009) The role of capillaroscopy in differentiation of primary and secondary Raynaud\u2019s phenomenon in rheumatic diseases: a review of the literature and two case reports. Rheumatol Int 29:1263\u20131271","journal-title":"Rheumatol Int"},{"key":"2109_CR35","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/01.rhu.0000191193.93720.95","volume":"11","author":"F Ingegnolli","year":"2005","unstructured":"Ingegnolli F, Zeni S, Meani L, Soldi A, Lurati A, Fantini F (2005) Evaluation of nailfold videocapillaroscopic abnormalities in patients with systemic lupus erythematosus. J Clin Rheumatol 11:295\u2013298","journal-title":"J Clin Rheumatol"},{"key":"2109_CR36","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1177\/096120339500400211","volume":"4","author":"O Bongard","year":"1995","unstructured":"Bongard O, Bounameaux H, Miescher PA, deMoerloose P (1995) Association of anticardiolipin antibodies and abnormal nailfold capillaroscopy in patients with systemic lupus erythematosus. Lupus 4:142\u2013144","journal-title":"Lupus"},{"key":"2109_CR37","first-page":"206","volume":"19","author":"P Jouanny","year":"1994","unstructured":"Jouanny P, Schmidt C, Feldmann L, Schmitt J (1994) Focus on a quick reading of nailfold capillaroscopy. J Mal Vasc 19:206\u2013209","journal-title":"J Mal Vasc"},{"key":"2109_CR38","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/0002-9343(88)90109-X","volume":"84","author":"O Fitzgerald","year":"1988","unstructured":"Fitzgerald O, Hess EV, O\u2019Connor GT, Spencer-Green G (1988) Prospective study of the evolution of Raynaud\u2019s phenomenon. Am J Med 84:718\u2013726","journal-title":"Am J Med"},{"key":"2109_CR39","first-page":"2226","volume":"22","author":"M Luggen","year":"1995","unstructured":"Luggen M, Belhorn L, Evans T, Fitzgerald O, Spencer-Green G (1995) The evolution of Raynaud\u2019s phenomenon: a longterm prospective study. J Rheumatol 22:2226\u20132232","journal-title":"J Rheumatol"},{"key":"2109_CR40","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1093\/rheumatology\/38.9.826","volume":"38","author":"M Tektonidou","year":"1999","unstructured":"Tektonidou M, Kaskani E, Skopouli FN, Moutsopoulos HM (1999) Microvascular abnormalities in Sj\u00f6gren\u2019s syndrome: nailfold capillaroscopy. Rheumatology 38:826\u2013830","journal-title":"Rheumatology"},{"key":"2109_CR41","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1136\/ard.29.3.244","volume":"29","author":"W Redisch","year":"1970","unstructured":"Redisch W (1970) Capillaroscopic observations in rheumatic diseases. Ann Rheum Dis 29:244\u2013253","journal-title":"Ann Rheum Dis"},{"key":"2109_CR42","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1002\/1529-0131(199811)41:11<1938::AID-ART7>3.0.CO;2-X","volume":"41","author":"C Zimmerman","year":"1998","unstructured":"Zimmerman C, Steiner G, Skriner K, Hassfeld W, Petera P, Smolen JS (1998) The concurrence of rheumatoid arthritis and limited systemic sclerosis. Clinical and serological characteristics of an overlap syndrome. Arthr Rheum 41:1938\u20131945","journal-title":"Arthr Rheum"},{"key":"2109_CR43","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1046\/j.1365-2133.1998.02458.x","volume":"139","author":"T Ohtsuka","year":"1998","unstructured":"Ohtsuka T, Tamura T, Yamakage A, Yamazaki S (1998) The predictive value of quantitative nailfold capillary microscopy in patients with undifferentiated connective tissue disease. Br J Dermatol 139:622\u2013629","journal-title":"Br J Dermatol"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-011-2109-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-011-2109-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-011-2109-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T07:21:31Z","timestamp":1559028091000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-011-2109-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,8]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["2109"],"URL":"https:\/\/doi.org\/10.1007\/s00296-011-2109-2","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,8]]}}}