{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:44:39Z","timestamp":1788925479132,"version":"build-2803163510"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T00:00:00Z","timestamp":1401926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s00296-014-3047-6","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T21:34:32Z","timestamp":1401917672000},"page":"43-52","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["The effects of an oral preparation containing hyaluronic acid (Oralvisc\u00ae) on obese knee osteoarthritis patients determined by pain, function, bradykinin, leptin, inflammatory cytokines, and heavy water analyses"],"prefix":"10.1007","volume":"35","author":[{"given":"F. R.","family":"Nelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. A.","family":"Zvirbulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Zonca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. W.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pasierb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Wilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Martinez-Puig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,6,5]]},"reference":[{"issue":"3","key":"3047_CR1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/jcp.21258","volume":"213","author":"MB Goldring","year":"2007","unstructured":"Goldring MB, Goldring SR (2007) Osteoarthritis. J Cell Physiol 213(3):626\u2013634. doi: 10.1002\/jcp.21258","journal-title":"J Cell Physiol"},{"issue":"4","key":"3047_CR2","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1089\/jwh.2007.371","volume":"16","author":"KA Theis","year":"2007","unstructured":"Theis KA, Helmick CG, Hootman JM (2007) Arthritis burden and impact are greater among U.S. women than men: intervention opportunities. J Womens Health (Larchmt) 16(4):441\u2013453","journal-title":"J Womens Health (Larchmt)"},{"issue":"2","key":"3047_CR3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/ard.60.2.91","volume":"60","author":"G Peat","year":"2001","unstructured":"Peat G, McCarney R, Croft P (2001) Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis 60(2):91\u201397","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"3047_CR4","doi-asserted-by":"crossref","first-page":"3546","DOI":"10.1002\/art.24984","volume":"60","author":"H Kotlarz","year":"2009","unstructured":"Kotlarz H, Gunnarsson CL, Fang H, Rizzo JA (2009) Insurer and out-of-pocket costs of osteoarthritis in the US: evidence from national survey data. Arthritis Rheum 60(12):3546\u20133553","journal-title":"Arthritis Rheum"},{"issue":"11","key":"3047_CR5","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1097\/JOM.0b013e3182337620","volume":"53","author":"A Berger","year":"2011","unstructured":"Berger A, Hartrick C, Edelsberg J, Sadosky A, Oster G (2011) Direct and indirect economic costs among private-sector employees with osteoarthritis. J Occup Environ Med 53(11):1228\u20131235. doi: 10.1097\/JOM.0b013e3182337620","journal-title":"J Occup Environ Med"},{"key":"3047_CR6","volume-title":"Musculoskeletal conditions in the United States","author":"A Praemer","year":"1999","unstructured":"Praemer A, Furner S, Rice DP (1999) Musculoskeletal conditions in the United States. American Academy of Orthopaedic Surgeons, Chicago"},{"issue":"3","key":"3047_CR7","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.pain.2010.04.003","volume":"149","author":"L Arendt-Nielsen","year":"2010","unstructured":"Arendt-Nielsen L, Nie H, Laursen MB, Laursen BS, Madeleine P, Simonsen OH, Graven-Nielsen T (2010) Sensitization in patients with painful knee osteoarthritis. Pain 149(3):573\u2013581. doi: 10.1016\/j.pain.2010.04.003","journal-title":"Pain"},{"issue":"5\u20136","key":"3047_CR8","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1242\/dmm.001180","volume":"2","author":"PL Huang","year":"2009","unstructured":"Huang PL (2009) A comprehensive definition for metabolic syndrome. Dis Model Mech 2(5\u20136):231\u2013237. doi: 10.1242\/dmm.001180","journal-title":"Dis Model Mech"},{"issue":"4","key":"3047_CR9","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/met.2009.0110","volume":"8","author":"MT Velasquez","year":"2010","unstructured":"Velasquez MT, Katz JD (2010) Osteoarthritis: another component of metabolic syndrome? Metab Syndr Relat Disord 8(4):295\u2013305. doi: 10.1089\/met.2009.0110","journal-title":"Metab Syndr Relat Disord"},{"issue":"11","key":"3047_CR10","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.joca.2012.06.006","volume":"20","author":"N Yoshimura","year":"2012","unstructured":"Yoshimura N, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T (2012) Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: a 3-year follow-up of the ROAD study. Osteoarthr Cartil 20(11):1217\u20131226. doi: 10.1016\/j.joca.2012.06.006","journal-title":"Osteoarthr Cartil"},{"issue":"5","key":"3047_CR11","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/01.bor.0000172800.49120.97","volume":"17","author":"DT Felson","year":"2005","unstructured":"Felson DT (2005) The sources of pain in knee osteoarthritis. Curr Opin Rheumatol 17(5):624\u2013628","journal-title":"Curr Opin Rheumatol"},{"issue":"5","key":"3047_CR12","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s11999-009-1193-z","volume":"468","author":"M Okamoto","year":"2010","unstructured":"Okamoto M, Atsuta Y (2010) Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. Clin Orthop Relat Res 468(5):1423\u20131427. doi: 10.1007\/s11999-009-1193-z","journal-title":"Clin Orthop Relat Res"},{"key":"3047_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-5-1","volume":"5","author":"JM Kelley","year":"2008","unstructured":"Kelley JM, Hughes LB, Bridges SL Jr (2008) Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis? J Neuroinflammation 5:1. doi: 10.1186\/1742-2094-5-1","journal-title":"J Neuroinflammation"},{"issue":"1","key":"3047_CR14","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1302\/0301-620X.79B1.6807","volume":"79","author":"JW Pritchett","year":"1997","unstructured":"Pritchett JW (1997) Substance P level in synovial fluid may predict pain relief after knee replacement. J Bone Joint Surg Br 79(1):114\u2013116","journal-title":"J Bone Joint Surg Br"},{"issue":"12","key":"3047_CR15","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.joca.2008.04.008","volume":"16","author":"YH Jean","year":"2008","unstructured":"Jean YH, Wen ZH, Chang YC, Hsieh SP, Lin JD, Tang CC, Chen WF, Chou AK, Wong CS (2008) Increase in excitatory amino acid concentration and transporters expression in osteoarthritic knees of anterior cruciate ligament transected rabbits. Osteoarthr Cartil 16(12):1442\u20131449","journal-title":"Osteoarthr Cartil"},{"issue":"4","key":"3047_CR16","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/00000542-198804000-00016","volume":"68","author":"SN Raja","year":"1988","unstructured":"Raja SN, Meyer RA, Campbell JN (1988) Peripheral mechanisms of somatic pain. Anesthesiology 68(4):571\u2013590","journal-title":"Anesthesiology"},{"issue":"4","key":"3047_CR17","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1152\/physrev.00048.2010","volume":"92","author":"G Petho","year":"2012","unstructured":"Petho G, Reeh PW (2012) Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors. Physiol Rev 92(4):1699\u20131775. doi: 10.1152\/physrev.00048.2010","journal-title":"Physiol Rev"},{"issue":"4","key":"3047_CR18","doi-asserted-by":"crossref","first-page":"600","DOI":"10.2106\/00004623-199704000-00021","volume":"79","author":"JA Buckwalter","year":"1997","unstructured":"Buckwalter JA (1997) Articular cartilage. Part I: tissue design and chondrocyte-matrix interactions. J Bone Joint Surg Am 79(4):600\u2013611","journal-title":"J Bone Joint Surg Am"},{"key":"3047_CR19","first-page":"215","volume-title":"Adult articular cartilage","author":"A Maroudas","year":"1979","unstructured":"Maroudas A (1979) Physicochemical properties of articular cartilage. In: Freeman MAR (ed) Adult articular cartilage, 2nd edn. Pitman Medical, Tunbridge Wells, pp 215\u2013290","edition":"2"},{"key":"3047_CR20","first-page":"116","volume-title":"Methods in cartilage research","author":"RM Mason","year":"1990","unstructured":"Mason RM (1990) Assessment of turnover of proteoglycans in vivo. In: Maroudas A, Kuettner KE (eds) Methods in cartilage research. Academic Press, New York, pp 116\u2013119"},{"issue":"10","key":"3047_CR21","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.joca.2009.03.020","volume":"17","author":"M Caligaris","year":"2009","unstructured":"Caligaris M, Canal CE, Ahmad CS, Gardner TR, Ateshian GA (2009) Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial fluid. Osteoarthr Cartil 17(10):1327\u20131332. doi: 10.1016\/j.joca.2009.03.020","journal-title":"Osteoarthr Cartil"},{"issue":"5","key":"3047_CR22","first-page":"946","volume":"33","author":"H Bagga","year":"2006","unstructured":"Bagga H, Burkhardt D, Sambrook P, March L (2006) Longterm effects of intraarticular hyaluronan on synovial fluid in osteoarthritis of the knee. J Rheumatol 33(5):946\u2013950","journal-title":"J Rheumatol"},{"issue":"2","key":"3047_CR23","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1161\/01.ATV.13.2.247","volume":"13","author":"PJ Jones","year":"1993","unstructured":"Jones PJ, Leitch CA, Li ZC, Connor WE (1993) Human cholesterol synthesis measurement using deuterated water. Theoretical and procedural considerations. Arterioscler Thromb 13(2):247\u2013253","journal-title":"Arterioscler Thromb"},{"issue":"3","key":"3047_CR24","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s10549-004-2228-5","volume":"89","author":"LM Misell","year":"2005","unstructured":"Misell LM, Hwang ES, Au A, Esserman L, Hellerstein MK (2005) Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. Breast Cancer Res Treat 89(3):257\u2013264. doi: 10.1007\/s10549-004-2228-5","journal-title":"Breast Cancer Res Treat"},{"issue":"4","key":"3047_CR25","doi-asserted-by":"crossref","first-page":"E790","DOI":"10.1152\/ajpendo.00402.2002","volume":"285","author":"SM Turner","year":"2003","unstructured":"Turner SM, Murphy EJ, Neese RA, Antelo F, Thomas T, Agarwal A, Go C, Hellerstein MK (2003) Measurement of TG synthesis and turnover in vivo by 2H2O incorporation into the glycerol moiety and application of MIDA. Am J Physiol Endocrinol Metab 285(4):E790\u2013E803","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"5","key":"3047_CR26","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.bbagen.2005.12.023","volume":"1760","author":"R Busch","year":"2006","unstructured":"Busch R, Kim YK, Neese RA, Schade-Serin V, Collins M, Awada M, Gardner JL, Beysen C, Marino ME, Misell LM, Hellerstein MK (2006) Measurement of protein turnover rates by heavy water labeling of nonessential amino acids. Biochim Biophys Acta 1760(5):730\u2013744. doi: 10.1016\/j.bbagen.2005.12.023","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"3047_CR27","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ab.2011.09.007","volume":"420","author":"JC Price","year":"2012","unstructured":"Price JC, Holmes WE, Li KW, Floreani NA, Neese RA, Turner SM, Hellerstein MK (2012) Measurement of human plasma proteome dynamics with (2)H(2)O and liquid chromatography tandem mass spectrometry. Anal Biochem 420(1):73\u201383. doi: 10.1016\/j.ab.2011.09.007","journal-title":"Anal Biochem"},{"key":"3047_CR28","first-page":"1472","volume":"31","author":"KW Li","year":"2006","unstructured":"Li KW, Turner SM (2006) Simultaneous measurement of cell and matrix turnover in cartilage: effects of IL-1 and BMP-7 in vitro and application in vivo [abstract]. Trans Annu Meet Orthop Res Soc 31:1472","journal-title":"Trans Annu Meet Orthop Res Soc"},{"issue":"3","key":"3047_CR29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/jor.21000","volume":"28","author":"R Gandhi","year":"2010","unstructured":"Gandhi R, Takahashi M, Syed K, Davey JR, Mahomed NN (2010) Relationship between body habitus and joint leptin levels in a knee osteoarthritis population. J Orthop Res 28(3):329\u2013333. doi: 10.1002\/jor.21000","journal-title":"J Orthop Res"},{"issue":"1","key":"3047_CR30","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1021\/ac701716q","volume":"80","author":"G Lis","year":"2008","unstructured":"Lis G, Wassenaar LI, Hendry MJ (2008) High-precision laser spectroscopy D\/H and 18O\/16O measurements of microliter natural water samples. Anal Chem 80(1):287\u2013293. doi: 10.1021\/ac701716q","journal-title":"Anal Chem"},{"issue":"7","key":"3047_CR31","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.joca.2009.01.006","volume":"17","author":"KW Li","year":"2009","unstructured":"Li KW, Siraj SA, Cheng EW, Awada M, Hellerstein MK, Turner SM (2009) A stable isotope method for the simultaneous measurement of matrix synthesis and cell proliferation in articular cartilage in vivo. Osteoarthr Cartil 17(7):923\u2013932. doi: 10.1016\/j.joca.2009.01.006","journal-title":"Osteoarthr Cartil"},{"key":"3047_CR32","first-page":"3","volume":"39","author":"EA Balazs","year":"1993","unstructured":"Balazs EA, Denlinger JL (1993) Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol Suppl 39:3\u20139","journal-title":"J Rheumatol Suppl"},{"issue":"1","key":"3047_CR33","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1053\/sarh.2002.33720","volume":"32","author":"P Ghosh","year":"2002","unstructured":"Ghosh P, Guidolin D (2002) Potential mechanism of action of intra-articular hyaluronan therapy in osteoarthritis: are the effects molecular weight dependent? Semin Arthritis Rheum 32(1):10\u201337","journal-title":"Semin Arthritis Rheum"},{"issue":"22","key":"3047_CR34","doi-asserted-by":"crossref","first-page":"10582","DOI":"10.1021\/jf8017029","volume":"56","author":"L Balogh","year":"2008","unstructured":"Balogh L, Polyak A, Mathe D, Kiraly R, Thuroczy J, Terez M, Janoki G, Ting Y, Bucci LR, Schauss AG (2008) Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. J Agric Food Chem 56(22):10582\u201310593. doi: 10.1021\/jf8017029","journal-title":"J Agric Food Chem"},{"key":"3047_CR35","doi-asserted-by":"crossref","first-page":"167928","DOI":"10.1100\/2012\/167928","volume":"2012","author":"T Tashiro","year":"2012","unstructured":"Tashiro T, Seino S, Sato T, Matsuoka R, Masuda Y, Fukui N (2012) Oral administration of polymer hyaluronic acid alleviates symptoms of knee osteoarthritis: a double-blind, placebo-controlled study over a 12-month period. Sci World J 2012:167928. doi: 10.1100\/2012\/167928","journal-title":"Sci World J"},{"issue":"32","key":"3047_CR36","doi-asserted-by":"crossref","first-page":"24751","DOI":"10.1074\/jbc.M110.104950","volume":"285","author":"A Asari","year":"2010","unstructured":"Asari A, Kanemitsu T, Kurihara H (2010) Oral administration of high molecular weight hyaluronan (900\u00a0kDa) controls immune system via Toll-like receptor 4 in the intestinal epithelium. J Biol Chem 285(32):24751\u201324758. doi: 10.1074\/jbc.M110.104950","journal-title":"J Biol Chem"},{"issue":"1","key":"3047_CR37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nrrheum.2010.196","volume":"7","author":"M Kapoor","year":"2011","unstructured":"Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H (2011) Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 7(1):33\u201342. doi: 10.1038\/nrrheum.2010.196","journal-title":"Nat Rev Rheumatol"},{"issue":"4","key":"3047_CR38","doi-asserted-by":"crossref","first-page":"306","DOI":"10.2174\/156652309788921044","volume":"9","author":"G Schulze-Tanzil","year":"2009","unstructured":"Schulze-Tanzil G, Zreiqat H, Sabat R, Kohl B, Halder A, Muller RD, John T (2009) Interleukin-10 and articular cartilage: experimental therapeutical approaches in cartilage disorders. Curr Gene Ther 9(4):306\u2013315","journal-title":"Curr Gene Ther"},{"issue":"3","key":"3047_CR39","first-page":"124","volume":"11","author":"C Golias","year":"2007","unstructured":"Golias C, Charalabopoulos A, Stagikas D, Charalabopoulos K, Batistatou A (2007) The kinin system\u2014bradykinin: biological effects and clinical implications. Multiple role of the kinin system\u2014bradykinin. Hippokratia 11(3):124\u2013128","journal-title":"Hippokratia"},{"key":"3047_CR40","author":"CA Karvonen-Gutierrez","year":"2012","unstructured":"Karvonen-Gutierrez CA, Harlow SD, Mancuso P, Jacobson J, de Leon CF, Nan B (2012) Leptin levels are associated with radiographic knee osteoarthritis among a cohort of mid-life women. Arthritis Care Res (Hoboken). doi: 10.1002\/acr.21922","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"8","key":"3047_CR41","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.joca.2007.04.015","volume":"15","author":"O Gualillo","year":"2007","unstructured":"Gualillo O (2007) Further evidence for leptin involvement in cartilage homeostases. Osteoarthritis Cartilage 15(8):857\u2013860. doi: 10.1016\/j.joca.2007.04.015","journal-title":"Osteoarthritis Cartilage"},{"issue":"6","key":"3047_CR42","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.jbspin.2008.07.008","volume":"75","author":"PP Gegout","year":"2008","unstructured":"Gegout PP, Francin PJ, Mainard D, Presle N (2008) Adipokines in osteoarthritis: friends or foes of cartilage homeostasis? Joint Bone Spine 75(6):669\u2013671. doi: 10.1016\/j.jbspin.2008.07.008","journal-title":"Joint Bone Spine"},{"issue":"12","key":"3047_CR43","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1136\/ard.2007.069377","volume":"66","author":"D Iliopoulos","year":"2007","unstructured":"Iliopoulos D, Malizos KN, Tsezou A (2007) Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. Ann Rheum Dis 66(12):1616\u20131621. doi: 10.1136\/ard.2007.069377","journal-title":"Ann Rheum Dis"},{"issue":"14","key":"3047_CR44","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.2174\/138945011798829393","volume":"12","author":"ML Bonet","year":"2011","unstructured":"Bonet ML, Granados N, Palou A (2011) Molecular players at the intersection of obesity and osteoarthritis. Curr Drug Targets 12(14):2103\u20132128","journal-title":"Curr Drug Targets"},{"key":"3047_CR45","doi-asserted-by":"crossref","unstructured":"Issa RI, Griffin TM (2012) Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation. Pathobiol Aging Age Relat Dis 2 (2012). doi: 10.3402\/pba.v2i0.17470","DOI":"10.3402\/pba.v2i0.17470"},{"issue":"3\u20134","key":"3047_CR46","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3233\/BIR-2008-0485","volume":"45","author":"TM Griffin","year":"2008","unstructured":"Griffin TM, Guilak F (2008) Why is obesity associated with osteoarthritis? Insights from mouse models of obesity. Biorheology 45(3\u20134):387\u2013398","journal-title":"Biorheology"},{"issue":"5","key":"3047_CR47","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/jbm.820130507","volume":"13","author":"W Iannacone","year":"1979","unstructured":"Iannacone W, Korostoff E, Pollack SR (1979) Microelectrode study of stress-generated potentials obtained from uniform and nonuniform compression of human bone. J Biomed Mater Res 13(5):753\u2013763","journal-title":"J Biomed Mater Res"},{"issue":"3","key":"3047_CR48","first-page":"244","volume":"66","author":"J Samuels","year":"2008","unstructured":"Samuels J, Krasnokutsky S, Abramson SB (2008) Osteoarthritis: a tale of three tissues. Bull NYU Hosp Jt Dis 66(3):244\u2013250","journal-title":"Bull NYU Hosp Jt Dis"},{"issue":"Suppl 2","key":"3047_CR49","doi-asserted-by":"crossref","first-page":"S244","DOI":"10.1016\/S1063-4584(10)60572-9","volume":"18","author":"V Castillo","year":"2010","unstructured":"Castillo V, Bendele AM, Li K, Martinez-Puig D, Turner SM, Chetrit C (2010) Effects of oral administration of Hyal-Joint\u00ae in 17\u00a0day rat developing type II collagen arthritis [abstract 545]. Osteoarthr Cartil 18(Suppl 2):S244\u2013S245","journal-title":"Osteoarthr Cartil"},{"issue":"Suppl 1","key":"3047_CR50","first-page":"S40","volume":"13","author":"KW Li","year":"2005","unstructured":"Li KW, Turner SM (2005) Turnover of synovial fluid hyaluronan: a potential kinetic biomarker of early osteoarthritis [abstract P61]. Osteoarthr Cartil 13(Suppl 1):S40","journal-title":"Osteoarthr Cartil"}],"updated-by":[{"DOI":"10.1007\/s00296-014-3078-z","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T00:00:00Z","timestamp":1404259200000}}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-014-3047-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-014-3047-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-014-3047-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T15:25:41Z","timestamp":1597937141000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-014-3047-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,5]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["3047"],"URL":"https:\/\/doi.org\/10.1007\/s00296-014-3047-6","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s00296-014-3078-z","asserted-by":"object"}]},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,5]]}}}