{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:06:49Z","timestamp":1762340809675},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s00296-015-3298-x","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T17:32:34Z","timestamp":1433439154000},"page":"1975-1983","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Beta-adducin and sodium\u2013calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis"],"prefix":"10.1007","volume":"35","author":[{"given":"Giuseppe A.","family":"Ramirez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Lanzani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrica P.","family":"Bozzolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Zagato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Citterio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nunzia","family":"Casamassima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Canti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Grazia","family":"Sabbadini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Rovere-Querini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Manunta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo A.","family":"Manfredi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,6,5]]},"reference":[{"issue":"2","key":"3298_CR1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.semnephrol.2010.01.007","volume":"30","author":"PS Ramos","year":"2010","unstructured":"Ramos PS, Brown EE, Kimberly RP, Langefeld CD (2010) Genetic factors predisposing to systemic lupus erythematosus and lupus nephritis. Semin Nephrol 30(2):164\u2013176. doi: 10.1016\/j.semnephrol.2010.01.007","journal-title":"Semin Nephrol"},{"key":"3298_CR2","author":"SA Chung","year":"2014","unstructured":"Chung SA, Brown EE, Williams AH, Ramos PS, Berthier CC, Bhangale T, Alarcon-Riquelme ME, Behrens TW, Criswell LA, Graham DC, Demirci FY, Edberg JC, Gaffney PM, Harley JB, Jacob CO, Kamboh MI, Kelly JA, Manzi S, Moser-Sivils KL, Russell LP, Petri M, Tsao BP, Vyse TJ, Zidovetzki R, Kretzler M, Kimberly RP, Freedman BI, Graham RR, Langefeld CD, for the International Consortium for Systemic Lupus Erythematosus G (2014) Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus. J Am Soc Nephrol. doi: 10.1681\/ASN.2013050446","journal-title":"J Am Soc Nephrol"},{"issue":"12","key":"3298_CR3","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1177\/0961203307083175","volume":"16","author":"A Zonana-Nacach","year":"2007","unstructured":"Zonana-Nacach A, Yanez P, Jimenez-Balderas FJ, Camargo-Coronel A (2007) Disease activity, damage and survival in Mexican patients with acute severe systemic lupus erythematosus. Lupus 16(12):997\u20131000. doi: 10.1177\/0961203307083175","journal-title":"Lupus"},{"issue":"8","key":"3298_CR4","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1093\/rheumatology\/ker101","volume":"50","author":"SC Croca","year":"2011","unstructured":"Croca SC, Rodrigues T, Isenberg DA (2011) Assessment of a lupus nephritis cohort over a 30-year period. Rheumatology (Oxford) 50(8):1424\u20131430. doi: 10.1093\/rheumatology\/ker101","journal-title":"Rheumatology (Oxford)"},{"issue":"2","key":"3298_CR5","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/ng.81","volume":"40","author":"JB Harley","year":"2008","unstructured":"International Consortium for Systemic Lupus Erythematosus G, Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel DB, Marion MC, Williams AH, Divers J, Wang W, Frank SG, Namjou B, Gabriel SB, Lee AT, Gregersen PK, Behrens TW, Taylor KE, Fernando M, Zidovetzki R, Gaffney PM, Edberg JC, Rioux JD, Ojwang JO, James JA, Merrill JT, Gilkeson GS, Seldin MF, Yin H, Baechler EC, Li QZ, Wakeland EK, Bruner GR, Kaufman KM, Kelly JA (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40(2):204\u2013210. doi: 10.1038\/ng.81","journal-title":"Nat Genet"},{"issue":"9","key":"3298_CR6","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/ng.200","volume":"40","author":"RR Graham","year":"2008","unstructured":"Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly MJ, Altshuler D, Moser KL, Gaffney PM (2008) Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 40(9):1059\u20131061. doi: 10.1038\/ng.200","journal-title":"Nat Genet"},{"issue":"9","key":"3298_CR7","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1056\/NEJMoa0707865","volume":"358","author":"G Hom","year":"2008","unstructured":"Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapaa-Dahlqvist S, Petri M, Manzi S, Seldin MF, Ronnblom L, Syvanen AC, Criswell LA, Gregersen PK, Behrens TW (2008) Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 358(9):900\u2013909. doi: 10.1056\/NEJMoa0707865","journal-title":"N Engl J Med"},{"issue":"7446","key":"3298_CR8","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nature11868","volume":"496","author":"M Kleinewietfeld","year":"2013","unstructured":"Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA (2013) Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature 496(7446):518\u2013522. doi: 10.1038\/nature11868","journal-title":"Nature"},{"key":"3298_CR9","first-page":"95","volume":"2","author":"GR Tintinger","year":"2009","unstructured":"Tintinger GR, Steel HC, Theron AJ, Anderson R (2009) Pharmacological control of neutrophil-mediated inflammation: strategies targeting calcium handling by activated polymorphonuclear leukocytes. Drug Des Devel Ther 2:95\u2013104","journal-title":"Drug Des Devel Ther"},{"issue":"3","key":"3298_CR10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/01.hjh.0000160210.48479.78","volume":"23","author":"C Lanzani","year":"2005","unstructured":"Lanzani C, Citterio L, Jankaricova M, Sciarrone MT, Barlassina C, Fattori S, Messaggio E, Serio CD, Zagato L, Cusi D, Hamlyn JM, Stella A, Bianchi G, Manunta P (2005) Role of the adducin family genes in human essential hypertension. J Hypertens 23(3):543\u2013549","journal-title":"J Hypertens"},{"issue":"5","key":"3298_CR11","doi-asserted-by":"crossref","first-page":"e19620","DOI":"10.1371\/journal.pone.0019620","volume":"6","author":"L Citterio","year":"2011","unstructured":"Citterio L, Simonini M, Zagato L, Salvi E, Delli Carpini S, Lanzani C, Messaggio E, Casamassima N, Frau F, D\u2019Avila F, Cusi D, Barlassina C, Manunta P (2011) Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension. PLoS ONE 6(5):e19620. doi: 10.1371\/journal.pone.0019620","journal-title":"PLoS ONE"},{"issue":"2","key":"3298_CR12","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00109-009-0549-x","volume":"88","author":"M Ferrandi","year":"2010","unstructured":"Ferrandi M, Cusi D, Molinari I, Del Vecchio L, Barlassina C, Rastaldi MP, Schena FP, Macciardi F, Marcantoni C, Roccatello D, Peters LL, Armelloni S, Min L, Giardino L, Mattinzoli D, Camisasca C, Palazzo F, Manunta P, Ferrari P, Bianchi G (2010) alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy. J Mol Med 88(2):203\u2013217. doi: 10.1007\/s00109-009-0549-x","journal-title":"J Mol Med"},{"issue":"4 Pt 2","key":"3298_CR13","first-page":"H1338","volume":"277","author":"M Ferrandi","year":"1999","unstructured":"Ferrandi M, Salardi S, Tripodi G, Barassi P, Rivera R, Manunta P, Goldshleger R, Ferrari P, Bianchi G, Karlish SJ (1999) Evidence for an interaction between adducin and Na(+)-K(+)-ATPase: relation to genetic hypertension. The American Journal of Physiology 277(4 Pt 2):H1338\u2013H1349","journal-title":"The American Journal of Physiology"},{"issue":"4","key":"3298_CR14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/00126097-200308000-00004","volume":"8","author":"V Tikhonoff","year":"2003","unstructured":"Tikhonoff V, Kuznetsova T, Stolarz K, Bianchi G, Casiglia E, Kawecka-Jaszcz K, Nikitin Y, Tizzone L, Wang JG, Staessen JA, European Project on Genes in Hypertension I (2003) Blood pressure phenotypes in relation to the beta-adducin C1797T polymorphism in the European Project on Genes in Hypertension (EPOGH). Blood Pressure Monitoring 8(4):151\u2013154. doi: 10.1097\/01.mbp.0000090397.29806.d6","journal-title":"Blood Pressure Monitoring"},{"issue":"6","key":"3298_CR15","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1046\/j.1523-1755.2002.00691.x","volume":"62","author":"JG Wang","year":"2002","unstructured":"Wang JG, Staessen JA, Barlassina C, Fagard R, Kuznetsova T, Struijker-Boudier HA, Zagato L, Citterio L, Messaggio E, Bianchi G (2002) Association between hypertension and variation in the alpha- and beta-adducin genes in a white population. Kidney Int 62(6):2152\u20132159. doi: 10.1046\/j.1523-1755.2002.00691.x","journal-title":"Kidney Int"},{"key":"3298_CR16","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/978-1-4614-4756-6_27","volume":"961","author":"RI Staiano","year":"2013","unstructured":"Staiano RI, Granata F, Secondo A, Petraroli A, Loffredo S, Annunziato L, Triggiani M, Marone G (2013) Human macrophages and monocytes express functional Na(+)\/Ca (2\u00a0+) exchangers 1 and 3. Adv Exp Med Biol 961:317\u2013326. doi: 10.1007\/978-1-4614-4756-6_27","journal-title":"Adv Exp Med Biol"},{"issue":"6","key":"3298_CR17","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/acr.21664","volume":"64","author":"BH Hahn","year":"2012","unstructured":"Hahn BH, McMahon MA, Wilkinson A, Wallace WD, Daikh DI, Fitzgerald JD, Karpouzas GA, Merrill JT, Wallace DJ, Yazdany J, Ramsey-Goldman R, Singh K, Khalighi M, Choi SI, Gogia M, Kafaja S, Kamgar M, Lau C, Martin WJ, Parikh S, Peng J, Rastogi A, Chen W, Grossman JM (2012) American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis. Arthritis Care Res (Hoboken) 64(6):797\u2013808. doi: 10.1002\/acr.21664","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"3298_CR18","unstructured":"1000 Genome Project. http:\/\/browser.1000genomes.org\/index.html"},{"issue":"1","key":"3298_CR19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/path.1389","volume":"201","author":"SL Bowen","year":"2003","unstructured":"Bowen SL, Bloor BK, Leigh IM, Waseem A (2003) Adducin expression in cutaneous and oral lesions: alpha- and beta-adducin transcripts down-regulate with keratinocyte differentiation in stratified epithelia. J Pathol 201(1):119\u2013126. doi: 10.1002\/path.1389","journal-title":"J Pathol"},{"issue":"7446","key":"3298_CR20","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nature11984","volume":"496","author":"C Wu","year":"2013","unstructured":"Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y, Regev A, Kuchroo VK (2013) Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature 496(7446):513\u2013517. doi: 10.1038\/nature11984","journal-title":"Nature"},{"issue":"3","key":"3298_CR21","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/cei.12286","volume":"176","author":"P Kolypetri","year":"2014","unstructured":"Kolypetri P, Randell E, Van Vliet BN, Carayanniotis G (2014) High salt intake does not exacerbate murine autoimmune thyroiditis. Clin Exp Immunol 176(3):336\u2013340. doi: 10.1111\/cei.12286","journal-title":"Clin Exp Immunol"},{"issue":"2","key":"3298_CR22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1161\/HYPERTENSIONAHA.108.119974","volume":"53","author":"MP Blaustein","year":"2009","unstructured":"Blaustein MP, Zhang J, Chen L, Song H, Raina H, Kinsey SP, Izuka M, Iwamoto T, Kotlikoff MI, Lingrel JB, Philipson KD, Wier WG, Hamlyn JM (2009) The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension 53(2):291\u2013298. doi: 10.1161\/HYPERTENSIONAHA.108.119974","journal-title":"Hypertension"},{"issue":"5","key":"3298_CR23","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/eji.200838792","volume":"39","author":"RI Staiano","year":"2009","unstructured":"Staiano RI, Granata F, Secondo A, Petraroli A, Loffredo S, Frattini A, Annunziato L, Marone G, Triggiani M (2009) Expression and function of Na+\/Ca2+ exchangers 1 and 3 in human macrophages and monocytes. Eur J Immunol 39(5):1405\u20131418. doi: 10.1002\/eji.200838792","journal-title":"Eur J Immunol"},{"key":"3298_CR24","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/978-1-4614-4756-6_24","volume":"961","author":"M Noda","year":"2013","unstructured":"Noda M, Ifuku M, Mori Y, Verkhratsky A (2013) Calcium influx through reversed NCX controls migration of microglia. Adv Exp Med Biol 961:289\u2013294. doi: 10.1007\/978-1-4614-4756-6_24","journal-title":"Adv Exp Med Biol"},{"issue":"Pt A","key":"3298_CR25","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neulet.2013.08.004","volume":"557","author":"W Rahman","year":"2013","unstructured":"Rahman W, Dickenson AH (2013) Voltage gated sodium and calcium channel blockers for the treatment of chronic inflammatory pain. Neurosci Lett 557(Pt A):19\u201326. doi: 10.1016\/j.neulet.2013.08.004","journal-title":"Neurosci Lett"},{"issue":"8","key":"3298_CR26","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3109\/08916934.2013.817560","volume":"46","author":"EP Bozzolo","year":"2013","unstructured":"Bozzolo EP, Ramirez GA, Bonavida G, Lanzani C, Scotti R, Dell\u2019antonio G, Baldissera E, Canti V, Manfredi AA, Rovere-Querini P, Sabbadini MG (2013) Efficacy and toxicity of treatments for nephritis in a series of consecutive lupus patients. Autoimmunity 46(8):537\u2013546. doi: 10.3109\/08916934.2013.817560","journal-title":"Autoimmunity"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-015-3298-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-015-3298-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-015-3298-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T11:28:31Z","timestamp":1559042911000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-015-3298-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,5]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["3298"],"URL":"https:\/\/doi.org\/10.1007\/s00296-015-3298-x","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,5]]}}}