{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T06:39:53Z","timestamp":1789799993785,"version":"4.0.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T00:00:00Z","timestamp":1495843200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"College graduate research and innovation of Jiangsu Province","award":["KYZZ15-0353"],"award-info":[{"award-number":["KYZZ15-0353"]}]},{"name":"Science Foundation of Nantong City","award":["MS22016028"],"award-info":[{"award-number":["MS22016028"]}]},{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation","doi-asserted-by":"crossref","award":["81671616, 81471603"],"award-info":[{"award-number":["81671616, 81471603"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Jiangsu Provincial Commission of Health and Family Planning Foundation","award":["H201317, H201623"],"award-info":[{"award-number":["H201317, H201623"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1007\/s00296-017-3746-x","type":"journal-article","created":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T11:17:18Z","timestamp":1495883838000},"page":"1187-1194","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["The rate of adherence to urate-lowering therapy and associated factors in Chinese gout patients: a cross-sectional study"],"prefix":"10.1007","volume":"37","author":[{"given":"Rulan","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixia","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuxiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liren","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifeng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,5,27]]},"reference":[{"issue":"10","key":"3746_CR1","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1136\/annrheumdis-2015-208237","volume":"74","author":"T Neogi","year":"2015","unstructured":"Neogi T, Jansen TLTA, Dalbeth N, Fransen J, Schumacher HR, Berendsen D, Brown M, Choi H, Edwards NL, Janssens HJEM, Liot\u00e9 F, Naden RP, Nuki G, Ogdie A, Perez-Ruiz F, Saag K, Singh JA, Sundy JS, Tausche A, Vaquez-Mellado J, Yarows SA, Taylor WJ (2015) 2015 Gout classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 74(10):1789\u20131798","journal-title":"Ann Rheum Dis"},{"key":"3746_CR2","first-page":"762820","volume":"2015","author":"R Liu","year":"2015","unstructured":"Liu R, Han C, Wu D, Xia X, Gu J, Guan H, Shan Z, Teng W (2015) Prevalence of hyperuricemia and gout in mainland China from 2000 to 2014: a systematic review and meta-analysis. Biomed Res Int 2015:762820","journal-title":"Biomed Res Int"},{"issue":"1","key":"3746_CR3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13075-015-0522-8","volume":"17","author":"C Kuo","year":"2015","unstructured":"Kuo C, Grainge MJ, See L, Yu K, Luo S, Zhang W, Doherty M (2015) Epidemiology and management of gout in Taiwan: a nationwide population study. Arthritis Res Ther 17(1):13","journal-title":"Arthritis Res Ther"},{"issue":"4","key":"3746_CR4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/annrheumdis-2013-204463","volume":"74","author":"CF Kuo","year":"2015","unstructured":"Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M (2015) Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Ann Rheum Dis 74(4):661\u2013667","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"3746_CR5","doi-asserted-by":"crossref","first-page":"R82","DOI":"10.1186\/ar4524","volume":"16","author":"JA Singh","year":"2014","unstructured":"Singh JA (2014) Facilitators and barriers to adherence to urate-lowering therapy in African-Americans with gout: a qualitative study. Arthritis Res Ther 16(2):R82","journal-title":"Arthritis Res Ther"},{"issue":"3","key":"3746_CR6","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/art.20405","volume":"51","author":"A Shoji","year":"2004","unstructured":"Shoji A, Yamanaka H, Kamatani N (2004) A retrospective study of the relationship between serum urate level and recurrent attacks of gouty arthritis: evidence for reduction of recurrent gouty arthritis with antihyperuricemic therapy. Arthritis Rheum 51(3):321\u2013325","journal-title":"Arthritis Rheum"},{"issue":"8","key":"3746_CR7","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1093\/rheumatology\/kem056a","volume":"46","author":"KM Jordan","year":"2007","unstructured":"Jordan KM, Cameron JS, Snaith M, Zhang W, Doherty M, Seckl J, Hingorani A, Jaques R, Nuki G (2007) British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of gout. Rheumatology (Oxford) 46(8):1372\u20131374","journal-title":"Rheumatology (Oxford)"},{"issue":"10","key":"3746_CR8","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1136\/ard.2006.055269","volume":"65","author":"W Zhang","year":"2006","unstructured":"Zhang W, Doherty M, Bardin T, Pascual E, Barskova V, Conaghan P, Gerster J, Jacobs J, Leeb B, Liote F, McCarthy G, Netter P, Nuki G, Perez-Ruiz F, Pignone A, Pimentao J, Punzi L, Roddy E, Uhlig T, Zimmermann-Gorska I (2006) EULAR evidence based recommendations for gout. Part II: management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65(10):1312\u20131324","journal-title":"Ann Rheum Dis"},{"key":"3746_CR9","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1001\/jama.289.21.2857","volume":"289","author":"R Kt","year":"2003","unstructured":"Kt R, Ca A (2003) Gout. JAMA 289:2857\u20132860","journal-title":"JAMA"},{"key":"3746_CR10","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0140-6736(09)60883-7","volume":"375","author":"P Richette","year":"2010","unstructured":"Richette P, Bardin T (2010) Gout. Lancet 375:318\u2013328","journal-title":"Lancet"},{"issue":"10","key":"3746_CR11","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1002\/acr.22336","volume":"66","author":"MA Vera De","year":"2014","unstructured":"De Vera MA, Marcotte G, Rai S, Galo JS, Bhole V (2014) Medication adherence in gout: a systematic review. Arthritis Care Res 66(10):1551\u20131559","journal-title":"Arthritis Care Res"},{"issue":"3","key":"3746_CR12","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s10067-014-2823-8","volume":"35","author":"B McGowan","year":"2016","unstructured":"McGowan B, Bennett K, Silke C, Whelan B (2016) Adherence and persistence to urate-lowering therapies in the Irish setting. Clin Rheumatol 35(3):715\u2013721","journal-title":"Clin Rheumatol"},{"issue":"4","key":"3746_CR13","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1592\/phco.28.4.437","volume":"28","author":"BA Briesacher","year":"2008","unstructured":"Briesacher BA, Andrade SE, Fouayzi H, Chan KA (2008) Comparison of drug adherence rates among patients with seven different medical conditions. Pharmacotherapy 28(4):437\u2013443","journal-title":"Pharmacotherapy"},{"issue":"6","key":"3746_CR14","doi-asserted-by":"crossref","first-page":"e0129364","DOI":"10.1371\/journal.pone.0129364","volume":"10","author":"T Mierlo van","year":"2015","unstructured":"van Mierlo T, Fournier R, Ingham M (2015) Targeting medication non-adherence behavior in selected autoimmune diseases: a systematic approach to digital health program development. PLoS One 10(6):e0129364","journal-title":"PLoS One"},{"issue":"6","key":"3746_CR15","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s10067-013-2168-8","volume":"32","author":"PC Robinson","year":"2013","unstructured":"Robinson PC, Schumacher HJ (2013) A qualitative and quantitative analysis of the characteristics of gout patient education resources. Clin Rheumatol 32(6):771\u2013778","journal-title":"Clin Rheumatol"},{"issue":"8","key":"3746_CR16","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1136\/ard.2008.092619","volume":"68","author":"JA Singh","year":"2009","unstructured":"Singh JA, Hodges JS, Asch SM (2009) Opportunities for improving medication use and monitoring in gout. Ann Rheum Dis 68(8):1265\u20131270","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"3746_CR17","first-page":"2635","volume":"26","author":"E Klerk de","year":"1999","unstructured":"de Klerk E, van der Heijde D, van der Tempel H, van der Linden S (1999) Development of a questionnaire to investigate patient compliance with antirheumatic drug therapy. J Rheumatol 26(12):2635\u20132641","journal-title":"J Rheumatol"},{"issue":"6","key":"3746_CR18","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s00296-014-3182-0","volume":"35","author":"AB Abdul-Sattar","year":"2015","unstructured":"Abdul-Sattar AB, Abou El Magd SA (2015) Determinants of medication non-adherence in Egyptian patients with systemic lupus erythematosus: sharkia Governorate. Rheumatol Int 35(6):1045\u20131051","journal-title":"Rheumatol Int"},{"issue":"Suppl 1","key":"3746_CR19","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1111\/j.1524-4733.2005.00066.x","volume":"8","author":"MJ Atkinson","year":"2005","unstructured":"Atkinson MJ, Kumar R, Cappelleri JC, Hass SL (2005) Hierarchical construct validity of the treatment satisfaction questionnaire for medication (TSQM version II) among outpatient pharmacy consumers. Value Health 8(Suppl 1):S9\u2013S24","journal-title":"Value Health"},{"key":"3746_CR20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1477-7525-1-20","volume":"1","author":"BFJ Bruce","year":"2003","unstructured":"Bruce BFJ (2003) The Stanford Health Assessment Questionnaire: dimensions and practical applications. Health Qual Life Outcomes 1:20","journal-title":"Health Qual Life Outcomes"},{"key":"3746_CR21","first-page":"735","volume":"10","author":"Y Xia","year":"2016","unstructured":"Xia Y, Yin R, Fu T, Zhang L, Zhang Q, Guo G, Li L, Gu Z (2016) Treatment adherence to disease-modifying antirheumatic drugs in Chinese patients with rheumatoid arthritis. Patient Prefer Adherence 10:735\u2013742","journal-title":"Patient Prefer Adherence"},{"key":"3746_CR22","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/1471-2474-13-174","volume":"13","author":"N Dalbeth","year":"2012","unstructured":"Dalbeth N, House ME, Horne A, Petrie KJ, McQueen FM, Taylor WJ (2012) Prescription and dosing of urate-lowering therapy, rather than patient behaviours, are the key modifiable factors associated with targeting serum urate in gout. BMC Musculoskelet Disord 13:174","journal-title":"BMC Musculoskelet Disord"},{"issue":"8","key":"3746_CR23","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1007\/s10067-016-3212-2","volume":"35","author":"B Spaetgens","year":"2016","unstructured":"Spaetgens B, Pustjens T, Scheepers LEJM, Janssens HJEM, van der Linden S, Boonen A (2016) Knowledge, illness perceptions and stated clinical practice behaviour in management of gout: a mixed methods study in general practice. Clin Rheumatol 35(8):2053\u20132061","journal-title":"Clin Rheumatol"},{"issue":"5","key":"3746_CR24","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/RHU.0b013e318228b4e2","volume":"17","author":"LY Zhang","year":"2011","unstructured":"Zhang LY, Schumacher HR, Su HH, Lie D, Dinnella J, Baker JF, Von Feldt JM (2011) Development and evaluation of a survey of gout patients concerning their knowledge about gout. J Clin Rheumatol 17(5):242\u2013248","journal-title":"J Clin Rheumatol"},{"issue":"11","key":"3746_CR25","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1007\/s10067-013-2333-0","volume":"32","author":"Q Li","year":"2013","unstructured":"Li Q, Dai L, Li Z, Liu H, Zou C, Ou-Yang X, Lu M, Li T, Li Y, Mo Y, Schumacher HR (2013) Questionnaire survey evaluating disease-related knowledge for 149 primary gout patients and 184 doctors in South China. Clin Rheumatol 32(11):1633\u20131640","journal-title":"Clin Rheumatol"},{"issue":"7","key":"3746_CR26","doi-asserted-by":"crossref","first-page":"e0159773","DOI":"10.1371\/journal.pone.0159773","volume":"11","author":"T Leclair","year":"2016","unstructured":"Leclair T, Carret A, Samson Y, Sultan S (2016) Stability and repeatability of the distress thermometer (DT) and the Edmonton symptom assessment system-revised (ESAS-r) with parents of childhood cancer survivors. PLoS One 11(7):e0159773","journal-title":"PLoS One"},{"issue":"10","key":"3746_CR27","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","volume":"166","author":"RL Spitzer","year":"2006","unstructured":"Spitzer RL, Kroenke K, Williams JB, Lowe B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 166(10):1092\u20131097","journal-title":"Arch Intern Med"},{"issue":"18","key":"3746_CR28","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1001\/jama.282.18.1737","volume":"282","author":"RL Spitzer","year":"1999","unstructured":"Spitzer RL, Kroenke K, Williams JB (1999) Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient Health Questionnaire. JAMA 282(18):1737\u20131744","journal-title":"JAMA"},{"key":"3746_CR29","volume-title":"SF-36 physical and mental health summary scales: a users manual","author":"JE Ware","year":"1994","unstructured":"Ware JE, Kosinski M, Keller SD (1994) SF-36 physical and mental health summary scales: a users manual. The Health Institute, New England Medical Centre, Boston"},{"issue":"7","key":"3746_CR30","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1080\/00325481.2016.1221732","volume":"128","author":"G Ruoff","year":"2016","unstructured":"Ruoff G, Edwards NL (2016) Overview of serum uric acid treatment targets in gout: why less than 6\u00a0mg\/dL? Postgrad Med 128(7):706\u2013715","journal-title":"Postgrad Med"},{"issue":"11","key":"3746_CR31","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1093\/rheumatology\/keu157","volume":"53","author":"A Latourte","year":"2014","unstructured":"Latourte A, Bardin T, Richette P (2014) Prophylaxis for acute gout flares after initiation of urate-lowering therapy. Rheumatology 53(11):1920\u20131926","journal-title":"Rheumatology"},{"issue":"1","key":"3746_CR32","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s40271-016-0184-x","volume":"10","author":"S Tatlock","year":"2017","unstructured":"Tatlock S, Rudell K, Panter C, Arbuckle R, Harrold LR, Taylor WJ, Symonds T (2017) What outcomes are important for gout patients? In-depth qualitative research into the gout patient experience to determine optimal endpoints for evaluating therapeutic interventions. Patient 10(1):65\u201379","journal-title":"Patient"},{"issue":"10","key":"3746_CR33","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.3899\/jrheum.151199","volume":"43","author":"R Wood","year":"2016","unstructured":"Wood R, Fermer S, Ramachandran S, Baumgartner S, Morlock R (2016) Patients with gout treated with conventional urate-lowering therapy: association with disease control, health-related quality of life, and work productivity. J Rheumatol 43(10):1897\u20131903","journal-title":"J Rheumatol"},{"issue":"5","key":"3746_CR34","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1007\/s10067-015-3039-2","volume":"35","author":"P Chandratre","year":"2016","unstructured":"Chandratre P, Mallen CD, Roddy E, Liddle J, Richardson J (2016) \u201cYou want to get on with the rest of your life\u201d: a qualitative study of health-related quality of life in gout. Clin Rheumatol 35(5):1197\u20131205","journal-title":"Clin Rheumatol"},{"issue":"Suppl 2","key":"3746_CR35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/rheumatology\/kep087","volume":"48","author":"F Perez-Ruiz","year":"2009","unstructured":"Perez-Ruiz F (2009) Treating to target: a strategy to cure gout. Rheumatology (Oxford) 48(Suppl 2):9\u201314","journal-title":"Rheumatology (Oxford)"},{"issue":"9","key":"3746_CR36","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/annrheumdis-2011-200801","volume":"71","author":"K Spencer","year":"2012","unstructured":"Spencer K, Carr A, Doherty M (2012) Patient and provider barriers to effective management of gout in general practice: a qualitative study. Ann Rheum Dis 71(9):1490\u20131495","journal-title":"Ann Rheum Dis"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-017-3746-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-017-3746-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-017-3746-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T04:22:33Z","timestamp":1498278153000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-017-3746-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,27]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["3746"],"URL":"https:\/\/doi.org\/10.1007\/s00296-017-3746-x","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,27]]}}}