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Dr. Horneff reports grants from Abbvie, Novartis, and Roche, and has received personal fees from Pfizer, outside the submitted work. Dr. Huppertz reports unconditional educational grants from Pfizer, Novartis, Abbvie, and LaRoche Shugai, and has received personal fees from Novartis outside the submitted work. Dr. Foeldvari reports consultations\u2009<\u200910.000 US $ from Abbvie, Chugai, Beyer, Roche-Genentecht, Novartis and has received Speaker fees from Pfizer, Abbvie, outside the submitted work. Dr. Ruperto has received grants from BMS, Hoffman-La Roche, Janssen, Novartis, Pfizer, Sobi, during the conduct of the study and personal fees and speaker honorarium from Abbvie, Ablynx, Amgen, AstraZeneca, Baxalta Biosimilars, Biogen Idec, Boehringer, Bristol Myers Squibb, Celgene, Eli-Lilly, EMD Serono, Gilead Sciences, Janssen, Medimmune, Novartis, Pfizer, Rpharm, Roche, Sanofi, Servier and Takeda. Dr. Consolaro, Dr. Bovis, Dr. Clara, Dr. K. Tzaribachev, Dr. N. Tzaribachev, Dr. H\u00fcgle, Dr. Ganser, Dr. Haas, Dr. Kallinich, Dr. Minden, and Dr. Weller have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study as per the requirement of the local ethical committee.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}