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Author Maruyama A has received a speaker honorarium from Janssen, Mitsubishi-Tanabe, Chugai, Astellas, and Bristol-Myers Squibb, outside the submitted work. Author Ono N has received personal fees from Mitsubishi-Tanabe, Chugai, Astellas, Takeda, Teijin, Abbvie, and Bristol-Myers Squibb, outside the submitted work. Author Arinobu Y has received personal fees from Mitsubishi-Tanabe, Chugai, Astellas, Takeda, Eisai, Actelion, Abbvie, Bristol-Myers Squibb, Daiichi-Sankyo, Ayumi, Asahikasei, and Nihon Shinyaku, outside the submitted work. Author Koarada S has received personal fees from Mitsubishi-Tanabe, Chugai, Astellas, Takeda, Eisai, Novartis, Abbvie, Bristol-Myers Squibb, Sanofi, Janssen, Pfizer, and Asahikasei, outside the submitted work. The authors Inokuchi S, Suematsu R, Sakai M, and Sadanaga Y declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required. This study was approved by the Saga University Hospital Ethics Committee (#2017-07-R-01) and the Kyushu University Hospital Ethics Committee (#29\u2013521).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}