{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T09:18:56Z","timestamp":1791537536209,"version":"4.3.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T00:00:00Z","timestamp":1564704000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T00:00:00Z","timestamp":1564704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1007\/s00296-019-04400-x","type":"journal-article","created":{"date-parts":[[2019,8,2]],"date-time":"2019-08-02T06:50:44Z","timestamp":1564728644000},"page":"115-120","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Chronic nonbacterial osteomyelitis in children: a multicenter case series"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-6357","authenticated-orcid":false,"given":"Sara","family":"Concha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4619-8027","authenticated-orcid":false,"given":"Alfonso","family":"Hern\u00e1ndez-Ojeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4023-0850","authenticated-orcid":false,"given":"Oscar","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2417-8471","authenticated-orcid":false,"given":"Cecilia","family":"Mendez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4048-8640","authenticated-orcid":false,"given":"Eduardo","family":"Talesnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7904-262X","authenticated-orcid":false,"given":"Arturo","family":"Borzutzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,2]]},"reference":[{"key":"4400_CR1","first-page":"329","volume":"15","author":"A Giedion","year":"1972","unstructured":"Giedion A, Holthusen W, Masel L, Vischer D (1972) Subacute and chronic \u201csymmetrical\u201d osteomyelitis. Ann Radiol 15:329\u2013342","journal-title":"Ann Radiol"},{"key":"4400_CR2","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.pcl.2018.04.003","volume":"65","author":"Y Zhao","year":"2018","unstructured":"Zhao Y, Ferguson PJ (2018) Chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis in children. Pediatr Clin North Am 65:783\u2013800. \nhttps:\/\/doi.org\/10.1016\/j.pcl.2018.04.003","journal-title":"Pediatr Clin North Am"},{"key":"4400_CR3","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1093\/rheumatology\/key058","volume":"57","author":"H Girschick","year":"2018","unstructured":"Girschick H, Finetti M, Orlando F et al (2018) The multifaceted presentation of chronic recurrent multifocal osteomyelitis: a series of 486 cases from the Eurofever international registry. Rheumatology (Oxford) 57:1203\u20131211. \nhttps:\/\/doi.org\/10.1093\/rheumatology\/key058","journal-title":"Rheumatology (Oxford)"},{"key":"4400_CR4","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1002\/art.39013","volume":"67","author":"J Wipff","year":"2015","unstructured":"Wipff J, Costantino F, Lemelle I et al (2015) A large national cohort of French patients with chronic recurrent multifocal osteitis. Arthritis Rheumatol 67:1128\u20131137. \nhttps:\/\/doi.org\/10.1002\/art.39013","journal-title":"Arthritis Rheumatol"},{"key":"4400_CR5","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1111\/j.1651-2227.2011.02205.x","volume":"100","author":"AF Jansson","year":"2011","unstructured":"Jansson AF, Grote V (2011) Nonbacterial osteitis in children: data of a German Incidence Surveillance Study. Acta Paediatr 100:1150\u20131157. \nhttps:\/\/doi.org\/10.1111\/j.1651-2227.2011.02205.x","journal-title":"Acta Paediatr"},{"key":"4400_CR6","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1002\/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V","volume":"42","author":"J Stocker","year":"1978","unstructured":"Stocker J, Ishak K (1978) Undifferentiated embryonal sarcoma of the liver. Cancer 42:336\u2013348","journal-title":"Cancer"},{"key":"4400_CR7","doi-asserted-by":"publisher","first-page":"672","DOI":"10.4103\/ortho.ijortho_464_17","volume":"52","author":"A Rao","year":"2018","unstructured":"Rao A, Mallya P, Ranjani S, Raghuram J (2018) Chronic recurrent multifocal osteomyelitis\u2014a case series from India. Indian J Orthop 52:672. \nhttps:\/\/doi.org\/10.4103\/ortho.ijortho_464_17","journal-title":"Indian J Orthop"},{"key":"4400_CR8","doi-asserted-by":"publisher","first-page":"e1190","DOI":"10.1542\/peds.2011-3788","volume":"130","author":"A Borzutzky","year":"2012","unstructured":"Borzutzky A, Stern S, Reiff A et al (2012) Pediatric chronic nonbacterial osteomyelitis. Pediatrics 130:e1190\u2013e1197. \nhttps:\/\/doi.org\/10.1542\/peds.2011-3788","journal-title":"Pediatrics"},{"key":"4400_CR9","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1002\/acr.23462","volume":"70","author":"Y Zhao","year":"2018","unstructured":"Zhao Y, Wu EY, Oliver MS, Cooper AM, Basiaga ML, Vora SS, Lee TC, Fox E, Amarilyo G, Stern SM, Dvergsten JA, Haines KA et al (2018) Consensus treatment plans for chronic nonbacterial osteomyelitis refractory to nonsteroidal antiinflammatory drugs and\/or with active spinal lesions. Arthritis Care Res 70:1228\u20131237. \nhttps:\/\/doi.org\/10.1002\/acr.23462","journal-title":"Arthritis Care Res"},{"key":"4400_CR10","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1002\/art.24402","volume":"60","author":"AF Jansson","year":"2009","unstructured":"Jansson AF, M\u00fcller TH, Gliera L et al (2009) Clinical score for nonbacterial osteitis in children and adults. Arthritis Rheum 60:1152\u20131159. \nhttps:\/\/doi.org\/10.1002\/art.24402","journal-title":"Arthritis Rheum"},{"key":"4400_CR11","doi-asserted-by":"publisher","first-page":"e017599","DOI":"10.1136\/bmjopen-2017-017599","volume":"7","author":"CCG Silier","year":"2017","unstructured":"Silier CCG, Greschik J, Gesell S et al (2017) Chronic non-bacterial osteitis from the patient perspective: a health services research through data collected from patient conferences. BMJ Open 7:e017599. \nhttps:\/\/doi.org\/10.1136\/bmjopen-2017-017599","journal-title":"BMJ Open"},{"key":"4400_CR12","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1148\/rg.294085244","volume":"29","author":"G Khanna","year":"2009","unstructured":"Khanna G, Sato T, Ferguson P (2009) Imaging of chronic recurrent multifocal osteomyelitis. Radiographics 29:1159\u20131177","journal-title":"Radiographics"},{"key":"4400_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2019.05.024","author":"LS Ording M\u00fcller","year":"2019","unstructured":"Ording M\u00fcller LS, Humphries P (2019) Commentary on: radiological diagnosis of chronic recurrent multifocal osteomyelitis using whole-body MRI-based lesion distribution patterns. Clin Radiol. \nhttps:\/\/doi.org\/10.1016\/j.crad.2019.05.024","journal-title":"Clin Radiol"},{"key":"4400_CR14","first-page":"578","volume":"30","author":"H Morbach","year":"2012","unstructured":"Morbach H, Schneider P, Schwarz T et al (2012) Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents. Clin Exp Rheumatol 30:578\u2013582","journal-title":"Clin Exp Rheumatol"},{"key":"4400_CR15","doi-asserted-by":"publisher","first-page":"R74","DOI":"10.1186\/ar2992","volume":"12","author":"C Beck","year":"2010","unstructured":"Beck C, Morbach H, Beer M et al (2010) Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment. Arthritis Res Ther 12:R74. \nhttps:\/\/doi.org\/10.1186\/ar2992","journal-title":"Arthritis Res Ther"},{"key":"4400_CR16","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.3899\/jrheum.161255","volume":"44","author":"A Schnabel","year":"2017","unstructured":"Schnabel A, Range U, Hahn G et al (2017) Treatment response and longterm outcomes in children with chronic nonbacterial osteomyelitis. J Rheumatol 44:1058\u20131065. \nhttps:\/\/doi.org\/10.3899\/jrheum.161255","journal-title":"J Rheumatol"},{"key":"4400_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2019.06.005","author":"J Su\u0142ko","year":"2019","unstructured":"Su\u0142ko J, Ebisz M, Bie\u0144 S et al (2019) Treatment of chronic recurrent multifocal osteomyelitis with bisphosphonates in children. Jt Bone Spine. \nhttps:\/\/doi.org\/10.1016\/j.jbspin.2019.06.005","journal-title":"Jt Bone Spine"},{"key":"4400_CR18","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s00296-018-4151-9","volume":"39","author":"Mikhail M Kostik","year":"2019","unstructured":"Kostik Mikhail M, Kopchak O, Chikova I, Isupova EMA (2019) Comparison of different treatment approaches of pediatric chronic non-bacterial osteomyelitis. Rheumatol Int 39:89\u201396. \nhttps:\/\/doi.org\/10.1007\/s00296-018-4151-9","journal-title":"Rheumatol Int"},{"key":"4400_CR19","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1093\/rheumatology\/kev013","volume":"54","author":"P Walsh","year":"2015","unstructured":"Walsh P, Manners PJ, Vercoe J et al (2015) Chronic recurrent multifocal osteomyelitis in children: nine years\u2019 experience at a statewide tertiary paediatric rheumatology referral centre. Rheumatology (Oxford) 54:1688\u20131691. \nhttps:\/\/doi.org\/10.1093\/rheumatology\/kev013","journal-title":"Rheumatology (Oxford)"},{"key":"4400_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jos.2018.06.015","volume":"25","author":"K Yamashita","year":"2018","unstructured":"Yamashita K, Calderaro C, Labianca L et al (2018) Chronic recurrent multifocal osteomyelitis (CRMO) involving spine: a case report and literature review. J Orthop Sci 25:1\u20136. \nhttps:\/\/doi.org\/10.1016\/j.jos.2018.06.015","journal-title":"J Orthop Sci"},{"key":"4400_CR21","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.3899\/jrheum.141026","volume":"42","author":"AM Voit","year":"2015","unstructured":"Voit AM, Arnoldi AP, Douis H et al (2015) Whole-body magnetic resonance imaging in chronic recurrent multifocal osteomyelitis: clinical longterm assessment may underestimate activity. J Rheumatol 42:1455\u20131462. \nhttps:\/\/doi.org\/10.3899\/jrheum.141026","journal-title":"J Rheumatol"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-019-04400-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-019-04400-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-019-04400-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T05:18:46Z","timestamp":1596259126000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-019-04400-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,2]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["4400"],"URL":"https:\/\/doi.org\/10.1007\/s00296-019-04400-x","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,2]]},"assertion":[{"value":"19 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The present study was approved by the Ethics Committee of the Hospital Dr. S\u00f3tero del R\u00edo and the Pontificia Universidad Cat\u00f3lica de Chile Scientific Ethics Committee (date 03 October 2017, number 170808001).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}