{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:02:20Z","timestamp":1767830540642,"version":"3.49.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s00296-020-04693-3","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T07:02:48Z","timestamp":1598770968000},"page":"1143-1150","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Is exposure to environmental factors associated with a characteristic clinical and laboratory profile in systemic sclerosis? A retrospective analysis"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9889-8629","authenticated-orcid":false,"given":"Lisbeth A.","family":"Aguila","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5665-4650","authenticated-orcid":false,"given":"Henrique Carri\u00e7o","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7168-5906","authenticated-orcid":false,"given":"Ana Cristina","family":"Medeiros-Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-1213","authenticated-orcid":false,"given":"Bruna Giusto","family":"Bunjes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0516-6918","authenticated-orcid":false,"given":"Ana Paula","family":"Luppino-Assad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9843-6686","authenticated-orcid":false,"given":"Percival D.","family":"Sampaio-Barros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"key":"4693_CR1","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1007\/s00281-015-0507-3","volume":"37","author":"I Marie","year":"2015","unstructured":"Marie I, Gehanno J-F (2015) Environmental risk factors of systemic sclerosis. Semin Immunopathol 37:463\u2013473. https:\/\/doi.org\/10.1007\/s00281-015-0507-3","journal-title":"Semin Immunopathol"},{"key":"4693_CR2","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s10067-016-3533-1","volume":"36","author":"M Rubio-Rivas","year":"2017","unstructured":"Rubio-Rivas M, Moreno R, Corbella X (2017) Occupational and environmental scleroderma. Systematic review and meta-analysis. Clin Rheumatol 36:569\u2013582. https:\/\/doi.org\/10.1007\/s10067-016-3533-1","journal-title":"Clin Rheumatol"},{"key":"4693_CR3","doi-asserted-by":"publisher","first-page":"2383","DOI":"10.3899\/jrheum.090207","volume":"36","author":"GF Mora","year":"2009","unstructured":"Mora GF (2009) Systemic sclerosis: environmental factors. J Rheumatol 36:2383\u20132396. https:\/\/doi.org\/10.3899\/jrheum.090207","journal-title":"J Rheumatol"},{"key":"4693_CR4","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1136\/oem.59.8.545","volume":"59","author":"E Diot","year":"2002","unstructured":"Diot E, Lesire V, Guilmot JL, Metzger MD, Pilore R, Rogier S et al (2002) Systemic sclerosis and occupational risk factors: a case-control study. Occup Environ Med 59:545\u2013549. https:\/\/doi.org\/10.1136\/oem.59.8.545","journal-title":"Occup Environ Med"},{"key":"4693_CR5","doi-asserted-by":"publisher","first-page":"e51506","DOI":"10.1371\/journal.pone.0051506","volume":"7","author":"C Barrag\u00e1n-Martinez","year":"2012","unstructured":"Barrag\u00e1n-Martinez C, Speck-Hernand\u00e9z CA, Montoya-Ortiz G, Mantilla RD, Anaya J-M, Rojas-Villaraga A (2012) Organic solvents as risk factor for autoimmune diseases: a systematic review and meta-analysis. PLoS ONE 7:e51506. https:\/\/doi.org\/10.1371\/journal.pone.0051506","journal-title":"PLoS ONE"},{"key":"4693_CR6","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.semarthrit.2015.06.004","volume":"459","author":"M Freire","year":"2015","unstructured":"Freire M, Alonso M, Rivera A, Sousa A, Soto A, Gomez-Sousa JM et al (2015) Clinical peculiarities of patients with scleroderma exposed to silica: a systematic review of the literature. Semin Arthritis Rheum 459:294\u2013300. https:\/\/doi.org\/10.1016\/j.semarthrit.2015.06.004","journal-title":"Semin Arthritis Rheum"},{"key":"4693_CR7","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1007\/s00296-015-3412-0","volume":"36","author":"LF Rocha","year":"2016","unstructured":"Rocha LF, Assad APL, Marangoni RG, Del Rio APT, Marques-Neto JF, Sampaio-Barros PD (2016) Systemic sclerosis and silica exposure: a rare association in a large Brazilian cohort. Rheumatol Int 36:697\u2013702. https:\/\/doi.org\/10.1007\/s00296-015-3412-0","journal-title":"Rheumatol Int"},{"key":"4693_CR8","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1080\/15287390600974593","volume":"70","author":"KM Semchuk","year":"2007","unstructured":"Semchuk KM, Rosenberg AM, McDuffie HH, Cessna AJ, Pahwa P, Irvine DG (2007) Antinuclear antibodies and bromoxynil exposure in a rural sample. J Toxicol Environ Health Part A 70:638\u2013657. https:\/\/doi.org\/10.1080\/15287390600974593","journal-title":"J Toxicol Environ Health Part A"},{"key":"4693_CR9","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1093\/ije\/dyy217","volume":"47","author":"A Watad","year":"2018","unstructured":"Watad A, Rosenberg V, Tiosano S, Cohen Tervaert JW, Yavne Y, Shoenfeld Y et al (2018) Silicone breast implants and the risk of autoimmune\/rheumatic disorders: a real world analysis. Int J Epidemiol 47:1846\u20131853. https:\/\/doi.org\/10.1093\/ije\/dyy217","journal-title":"Int J Epidemiol"},{"key":"4693_CR10","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.semarthrit.2018.06.009","volume":"48","author":"C Ferri","year":"2018","unstructured":"Ferri C, Artoni E, Sighinolfi GL, Luppi F, Zelent G, Colaci M et al (2018) High serum levels of silica nanoparticles in systemic sclerosis patients with occupational exposure: possible pathogenetic role in disease phenotypes. Semin Arthritis Rheum 48:475\u2013481. https:\/\/doi.org\/10.1016\/j.semarthrit.2018.06.009","journal-title":"Semin Arthritis Rheum"},{"key":"4693_CR11","doi-asserted-by":"publisher","first-page":"596","DOI":"10.26444\/aaem\/75894","volume":"25","author":"I Walecka","year":"2018","unstructured":"Walecka I, Roszkiewicz M, Malewska A (2018) Potential occupational and environmental factors in SSc onset. Ann Agric Environ Med 25:596\u2013601. https:\/\/doi.org\/10.26444\/aaem\/75894","journal-title":"Ann Agric Environ Med"},{"key":"4693_CR12","doi-asserted-by":"publisher","first-page":"rky041","DOI":"10.1093\/rap\/rky041","volume":"2","author":"S Abbbot","year":"2018","unstructured":"Abbbot S, Bossingham D, Proudman S, Costa C, Ho-Huynh A (2018) Risk factors for the development of systemic sclerosis: a systematic review of the literature. Rheumatol Adv Pract 2:rky041. https:\/\/doi.org\/10.1093\/rap\/rky041","journal-title":"Rheumatol Adv Pract"},{"key":"4693_CR13","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.1002\/art.38098","volume":"65","author":"F Van den Hoogen","year":"2013","unstructured":"Van den Hoogen F, Khanna D, Franssen J, Johnson S, Baron M, Tyndall A et al (2013) 2013 classification criteria for systemic sclerosis: an American College of Rheumatology\/European League against Rheumatism collaborative initiative. Arthritis Rheum 65:2737\u20132747. https:\/\/doi.org\/10.1002\/art.38098","journal-title":"Arthritis Rheum"},{"key":"4693_CR14","first-page":"202","volume":"15","author":"EC LeRoy","year":"1988","unstructured":"LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr et al (1988) Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 15:202\u2013205","journal-title":"J Rheumatol"},{"key":"4693_CR15","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s00420-003-0462-5","volume":"77","author":"M Bovenzi","year":"2004","unstructured":"Bovenzi M, Barbone F, Pisa FE, Betta A, Romeo L, Tonello A et al (2004) A case-control study of occupational exposures and systemic sclerosis. Int Arch Occup Environ Health 77:10\u201316. https:\/\/doi.org\/10.1007\/s00420-003-0462-5","journal-title":"Int Arch Occup Environ Health"},{"key":"4693_CR16","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1745-6673-1-15","volume":"1","author":"B Kutting","year":"2006","unstructured":"Kutting B, Uter W, Drexler H (2006) Is occupational exposure to solvents associated with an increased risk for developing systemic scleroderma? J Occup Med Toxicol 1:15. https:\/\/doi.org\/10.1186\/1745-6673-1-15","journal-title":"J Occup Med Toxicol"},{"key":"4693_CR17","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1007\/s00420-009-0505-7","volume":"83","author":"ZD McCormic","year":"2010","unstructured":"McCormic ZD, Khuder SS, Aryal BK, Ames AL, Khuder SA (2010) Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup Environ Health 83:763\u2013769. https:\/\/doi.org\/10.1007\/s00420-009-0505-7","journal-title":"Int Arch Occup Environ Health"},{"key":"4693_CR18","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.autrev.2013.10.002","volume":"13","author":"I Marie","year":"2014","unstructured":"Marie I, Gehanno J-F, Bubenheim M, Duval-Modeste AB, Joly P, Dominique S et al (2014) Prospective study to evaluate the association between systemic sclerosis and occupational exposure and review of the literature. Autoimmune Rev 13:151\u2013156. https:\/\/doi.org\/10.1016\/j.autrev.2013.10.002","journal-title":"Autoimmune Rev"},{"key":"4693_CR19","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s10067-019-04575-5","volume":"39","author":"C Mendes","year":"2020","unstructured":"Mendes C, Viana VS, Pasoto SG, Leon EP, Bonfa E, Sampaio-Barros PD (2020) Clinical and laboratory features of African-Brazilian patients with systemic sclerosis. Clin Rheumatol 39:9\u201317. https:\/\/doi.org\/10.1007\/s10067-019-04575-5","journal-title":"Clin Rheumatol"},{"key":"4693_CR20","doi-asserted-by":"publisher","first-page":"e8980","DOI":"10.1097\/MD.0000000000008980","volume":"51","author":"ND Morgan","year":"2017","unstructured":"Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA Jr, Steen VD et al (2017) Clinical and serological features of systemic sclerosis in a multicenter African American cohort: analysis of the genome research in African American scleroderma patients clinical database. Medicine (Baltimore) 51:e8980. https:\/\/doi.org\/10.1097\/MD.0000000000008980","journal-title":"Medicine (Baltimore)"},{"key":"4693_CR21","first-page":"2369","volume":"26","author":"PJ Nietert","year":"1999","unstructured":"Nietert PJ, Sutherland SE, Silver RM, Pandey JP, Dosemeci M (1999) Solvent oriented hobbies and the risk of systemic sclerosis. J Rheumatol 26:2369\u20132372","journal-title":"J Rheumatol"},{"key":"4693_CR22","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1093\/aje\/kwf223","volume":"157","author":"DH Garabrant","year":"2003","unstructured":"Garabrant DH, Lacey JV Jr, Laing TJ, Gillespie BW, Mayes MD, Cooper BC et al (2003) Scleroderma and solvent exposure among women. Am J Epidemiol 157:493\u2013500. https:\/\/doi.org\/10.1093\/aje\/kwf223","journal-title":"Am J Epidemiol"},{"key":"4693_CR23","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1080\/009841099157674","volume":"57","author":"AM Rosenberg","year":"1999","unstructured":"Rosenberg AM, Semchuk KM, McDuffie HH, Ledingham DL, Cordeiro DM, Cessna AJ et al (1999) Prevalence of antinuclear antibodies in a rural population. J Toxic Environ Health Part A 57:225\u2013236. https:\/\/doi.org\/10.1080\/009841099157674","journal-title":"J Toxic Environ Health Part A"},{"key":"4693_CR24","doi-asserted-by":"publisher","first-page":"4227","DOI":"10.1007\/s00296-018-4227-6","volume":"39","author":"R Andreussi","year":"2019","unstructured":"Andreussi R, Silva LMB, da Silva HC, Luppino-Assad AP, Andrade DCO, Sampaio-Barros PD (2019) Systemic sclerosis induced by the use of cocaine: Is there an association? Rheumatol Int 39:4227\u20134236. https:\/\/doi.org\/10.1007\/s00296-018-4227-6","journal-title":"Rheumatol Int"},{"key":"4693_CR25","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1097\/BOR.0b013e32835cfc2d","volume":"25","author":"P Dospinescu","year":"2013","unstructured":"Dospinescu P, Jones GT, Basu N (2013) Environmental risk factors in systemic sclerosis. Curr Opin Rheumatol 25:179\u2013183. https:\/\/doi.org\/10.1097\/BOR.0b013e32835cfc2d","journal-title":"Curr Opin Rheumatol"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-020-04693-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00296-020-04693-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-020-04693-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T23:10:15Z","timestamp":1630278615000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00296-020-04693-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,30]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["4693"],"URL":"https:\/\/doi.org\/10.1007\/s00296-020-04693-3","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,30]]},"assertion":[{"value":"24 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Aguila declares no conflicts of interest related to this article. Dr. Carri\u00e7o da Silva declares no conflicts of interest related to this article. Dr. Medeiros-Ribeiro declares no conflicts of interest related to this article. Dr. Bunjes declares no conflicts of interest related to this article.Dr. Luppino-Assad declares no conflicts of interest related to this article. Dr. Sampaio-Barros declares no conflicts of interest related to this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}