{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:11:12Z","timestamp":1789582272604,"version":"build-2803163510"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s00296-020-04783-2","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T13:02:51Z","timestamp":1611406971000},"page":"611-616","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effect of add-on methotrexate in polymyalgia rheumatica patients flaring on glucocorticoids tapering: a retrospective study"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3103-1374","authenticated-orcid":false,"given":"Diane","family":"Marsman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bolhuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan den","family":"Broeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"van den Hoogen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfons","family":"den Broeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aatke","family":"van der Maas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,23]]},"reference":[{"key":"4783_CR1","doi-asserted-by":"publisher","first-page":"2442","DOI":"10.1001\/jama.2016.5444","volume":"315","author":"F Buttgereit","year":"2016","unstructured":"Buttgereit F, Dejaco C, Matteson EL et al (2016) Polymyalgia rheumatica and giant cell arteritis: a systematic review. JAMA 315:2442\u20132458","journal-title":"JAMA"},{"issue":"10103","key":"4783_CR2","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1016\/S0140-6736(17)31825-1","volume":"390","author":"MA Gonz\u00e1lez-Gay","year":"2017","unstructured":"Gonz\u00e1lez-Gay MA, Matteson EL, Casta\u00f1eda S (2017) Polymyalgia rheumatica. Lancet 390(10103):1700","journal-title":"Lancet"},{"issue":"5 Suppl 68","key":"4783_CR3","first-page":"S143","volume":"29","author":"R Caporali","year":"2011","unstructured":"Caporali R, Cimmino MA, Montecucco C et al (2011) Glucocorticoid treatment of polymyalgia rheumatica. ClinExpRheumatol 29(5 Suppl 68):S143\u2013S147","journal-title":"ClinExpRheumatol"},{"issue":"10","key":"4783_CR4","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1136\/annrheumdis-2015-207492","volume":"74","author":"C Dejaco","year":"2015","unstructured":"Dejaco C, Singh YP, Perel P, European League Against Rheumatism, American College of Rheumatology (2015) Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism\/American College of Rheumatology collaborative initiative. Ann Rheum Dis 74(10):1799\u20131807","journal-title":"Ann Rheum Dis"},{"key":"4783_CR5","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1136\/ard.55.4.218","volume":"55","author":"MJ van der Veen","year":"1996","unstructured":"van der Veen MJ, Dinant HJ, van Booma C et al (1996) Can methotrexate be used as a steroid sparing agent in the treatment of polymyalgia rheumatica and giant cell arteritis? Ann Rheum Dis 55:218\u2013223","journal-title":"Ann Rheum Dis"},{"key":"4783_CR6","doi-asserted-by":"crossref","unstructured":"Caporali R, Cimmino MA, Ferraccioli G, et al (2004) Prednisone plus methotrexate for polymyalgia rheumatica a randomized, double-blind, placebo-controlled trial background: steroids are the standard treatment for polymyal [Internet].","DOI":"10.7326\/0003-4819-141-7-200410050-00005"},{"issue":"3","key":"4783_CR7","first-page":"395","volume":"26","author":"MA Cimmino","year":"2008","unstructured":"Cimmino MA, Gerli R, Bocci EB et al (2008) Long-term follow-up of polymyalgia rheumatica patients treated with methotrexate and steroids. ClinExpRheumatol 26(3):395\u2013400","journal-title":"ClinExpRheumatol"},{"issue":"4","key":"4783_CR8","first-page":"624","volume":"23","author":"G Ferraccioli","year":"1996","unstructured":"Ferraccioli G, Salaffi F, De Vita S, Casatta LBE (1996) Methotrexate in polymyalgia rheumatica: preliminary results of an open, randomized study. J Rheumatol 23(4):624\u2013628","journal-title":"J Rheumatol"},{"key":"4783_CR9","first-page":"1410","volume":"18","author":"L Quartuccio","year":"2018","unstructured":"Quartuccio L, Gregoraci G, Isola M et al (2018) Retrospective analysis of the usefulness of a protocol with high-dose methotrexate in polymyalgia rheumatica: results of a single-center cohort of 100 patients. GeriatrGerontol Int 18:1410\u20131414","journal-title":"GeriatrGerontol Int"},{"issue":"9","key":"4783_CR10","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1111\/imj.14779","volume":"50","author":"C Ruediger","year":"2020","unstructured":"Ruediger C, Nguyen L, Black R et al (2020) Efficacy of methotrexate in polymyalgia rheumatica in routine rheumatology clinical care. Intern Med J 50(9):1067\u20131072","journal-title":"Intern Med J"},{"issue":"2","key":"4783_CR11","first-page":"S213","volume":"26","author":"ML De la Torre","year":"2020","unstructured":"De la Torre ML, Rodr\u00edguez AM, Pisoni CN (2020) Usefulness of methotrexate in the reduction of relapses and recurrences in polymyalgia rheumatica: an observational study. J ClinRheumatol 26(2):S213\u2013S217","journal-title":"J ClinRheumatol"},{"key":"4783_CR12","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s00296-017-3874-3","volume":"38","author":"K Albrecht","year":"2018","unstructured":"Albrecht K, Huscher D, Buttgereit F et al (2018) Long-term glucocorticoid treatment in patients with polymyalgia rheumatica, giant cell arteritis, or both diseases: results from a national rheumatology database. Rheumatol Int 38:569\u2013577. https:\/\/doi.org\/10.1007\/s00296-017-3874-3","journal-title":"Rheumatol Int"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-020-04783-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00296-020-04783-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-020-04783-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T10:50:13Z","timestamp":1617274213000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00296-020-04783-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,23]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["4783"],"URL":"https:\/\/doi.org\/10.1007\/s00296-020-04783-2","relation":{},"ISSN":["0172-8172","1437-160X"],"issn-type":[{"value":"0172-8172","type":"print"},{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,23]]},"assertion":[{"value":"29 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standard"}},{"value":"None of the authors have conflicting interests in the context of this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}