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Regarding growing interest in the implementation of the patient-reported outcome measures (PROMs), we aimed to review the non-disease specific PROMs addressing HRQL assessment, potentially useful in the clinical care of JIA and daily practice. A systematic literature search was conducted using MEDLINE\/PubMed, Google Scholar, Scopus and Embase databases (1990 to 2021), with a focus on the recent 5-years period. Entry keywords included the terms: \u201cchildren\u201d, \u201cadolescents\u201d, \u201cJIA\u201d, \u201cchronic diseases\u201d, \u201cHRQL\u201d, \u201cPROMs\u201d and wordings for the specific tools. Several available PROMs intended to measure HRQL, non-specific to JIA, were identified. The presented outcomes differed in psychometric properties, yet all were feasible in assessing HRQL in healthy children and those with chronic diseases. Both EQ-5D-Y and PedsQL have already been tested in JIA, showing relevant reliability, validity, and similar efficiency as disease-specific measurements. For PROMIS\u00ae PGH-7 and PGH-7\u2009+\u20092, such validation and cross-cultural adaptation need to be performed. Considering the future directions in pediatric rheumatology, the large-scale implementation of PROMIS\u00ae PGH-7 and PGH-7\u2009+\u20092 in JIA offers a particularly valuable opportunity. The PROMs reflect the patient perception of the chronic disease and allow to understand child\u2019s opinions. The PROMs may provide an important element of the holistic medical care of patients with JIA and a standardized tool for clinical outcomes, monitoring disease severity and response to treatment.<\/jats:p>","DOI":"10.1007\/s00296-021-05077-x","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T16:02:57Z","timestamp":1640966577000},"page":"191-203","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Non-disease specific patient-reported outcome measures of health-related quality of life in juvenile idiopathic arthritis: a systematic review of current research and practice"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-3645","authenticated-orcid":false,"given":"Justyna","family":"M\u0142y\u0144czyk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6150-0971","authenticated-orcid":false,"given":"Pawe\u0142","family":"Abramowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4267-1887","authenticated-orcid":false,"given":"Maciej K.","family":"Stawicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1230-332X","authenticated-orcid":false,"given":"Jerzy","family":"Konstantynowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,31]]},"reference":[{"issue":"10","key":"5077_CR1","doi-asserted-by":"publisher","first-page":"2641","DOI":"10.1007\/s11136-019-02214-9","volume":"28","author":"K Haraldstad","year":"2019","unstructured":"Haraldstad K, Wahl A, Anden\u00e6s R et al (2019) A systematic review of quality of life research in medicine and health sciences. 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