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However, variability in biopsy practices may result in a heterogenous patient experience. The existing literature offers limited insights into the experiences and perspectives of patients undergoing muscle biopsy. Methods: This study employed a 27-item online survey to comprehensively characterise the experience of muscle biopsy among Australian patients, including their concerns, beliefs about procedure utility, information sources, physical sensations, perceived complications and recovery. Results: A total of 111 Australian individuals who reported a diagnosis of IIM completed the survey, with data collected from March to June 2023. Most participants had inclusion body myositis (76\/111, 68.5%) and had undergone one biopsy procedure (87\/111, 78.4%) as part of their IIM work-up. Nine of the 111 respondents did not undergo a muscle biopsy. The procedure was well-tolerated by many respondents, however, a notable number of respondents experienced post-procedural pain lasting\u2009&gt;\u200972\u00a0h (27\/102, 26.5%), increasing weakness post-biopsy (13.7%), numbness at the biopsy site (18\/102, 17.6%) and a recovery time beyond 3 days (36\/102, 35.3%). A substantial minority (30\/111, 27%) felt they were inadequately informed about the risks and benefits of the procedure. Conclusions: This survey highlights that although muscle biopsy is often well-tolerated, there are considerable patient concerns that are often inadequately addressed. Our findings underscore the need for improved patient-doctor communication and support throughout the biopsy process.<\/jats:p>","DOI":"10.1007\/s00296-024-05668-4","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T04:13:20Z","timestamp":1722399200000},"page":"2129-2137","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Patient experiences of muscle biopsy in idiopathic inflammatory myopathies: a cross-sectional survey"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4718-8525","authenticated-orcid":false,"given":"Benjamin","family":"Sutu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Maxwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6822-5711","authenticated-orcid":false,"given":"Shereen","family":"Oon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4636-729X","authenticated-orcid":false,"given":"Laura","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8528-4361","authenticated-orcid":false,"given":"Jessica","family":"Day","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"issue":"3","key":"5668_CR1","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1111\/cei.12194","volume":"175","author":"PO Carstens","year":"2014","unstructured":"Carstens PO, Schmidt J (2014) Diagnosis, pathogenesis and treatment of myositis: recent advances. 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