{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:40:41Z","timestamp":1773362441812,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T00:00:00Z","timestamp":1734134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T00:00:00Z","timestamp":1734134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"DOI":"10.1007\/s00296-024-05762-7","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T06:57:24Z","timestamp":1734159444000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Joint swelling in the hand in rheumatoid arthritis: agreement between clinical evaluation, ultrasonography, magnetic resonance imaging and patient self-evaluation"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5118-643X","authenticated-orcid":false,"given":"Lau","family":"Brix","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2352-0549","authenticated-orcid":false,"given":"Agnete","family":"Hedemann-Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9029-3534","authenticated-orcid":false,"given":"Lise","family":"Medrud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7181-1113","authenticated-orcid":false,"given":"Ulrich","family":"Fredberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0426-4962","authenticated-orcid":false,"given":"Torkell","family":"Ellingsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,14]]},"reference":[{"issue":"Suppl 3","key":"5762_CR1","doi-asserted-by":"publisher","first-page":"S265","DOI":"10.1186\/ar578","volume":"4","author":"AJ Silman","year":"2002","unstructured":"Silman AJ, Pearson JE (2002) Epidemiology and genetics of rheumatoid arthritis. Arthritis Res 4(Suppl 3):S265\u2013S272. https:\/\/doi.org\/10.1186\/ar578","journal-title":"Arthritis Res"},{"key":"5762_CR2","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/nrrheum.2017.96","volume":"13","author":"C Ospelt","year":"2017","unstructured":"Ospelt C, Frank-Bertoncelj M (2017) Why location matters - site-specific factors in rheumatic diseases. Nat Rev Rheumatol 13:433\u2013442. https:\/\/doi.org\/10.1038\/nrrheum.2017.96","journal-title":"Nat Rev Rheumatol"},{"key":"5762_CR3","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1002\/art.27584","volume":"62","author":"D Aletaha","year":"2010","unstructured":"Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO III et al (2010) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Arthritis Rheum 62:2569\u20132581. https:\/\/doi.org\/10.1002\/art.27584","journal-title":"Arthritis Rheum"},{"key":"5762_CR4","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1002\/art.38306","volume":"66","author":"J Widdifield","year":"2014","unstructured":"Widdifield J, Paterson JM, Bernatsky S, Tu K, Tomlinson G, Kuriya B et al (2014) The epidemiology of rheumatoid arthritis in Ontario, Canada. Arthritis Rheumatol 66:786\u2013793. https:\/\/doi.org\/10.1002\/art.38306","journal-title":"Arthritis Rheumatol"},{"issue":"Suppl 1","key":"5762_CR5","doi-asserted-by":"publisher","first-page":"S41","DOI":"10.1097\/sap.0000000000000685","volume":"76","author":"JH Hsueh","year":"2016","unstructured":"Hsueh JH, Liu WC, Yang KC, Hsu KC, Lin CT, Chen LW (2016) Spontaneous Extensor Tendon Rupture in the Rheumatoid Wrist: Risk Factors and Preventive Role of Extended Tenosynovectomy. Ann Plast Surg 76(Suppl 1):S41\u2013S47. https:\/\/doi.org\/10.1097\/sap.0000000000000685","journal-title":"Ann Plast Surg"},{"key":"5762_CR6","doi-asserted-by":"publisher","first-page":"i1777","DOI":"10.1002\/14651858.CD010227.pub2","volume":"353","author":"GS Hazlewood","year":"2016","unstructured":"Hazlewood GS, Barnabe C, Tomlinson G, Marshall D, Devoe D, Bombardier C (2016) Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying antirheumatic drugs for rheumatoid arthritis: abridged Cochrane systematic review and network meta-analysis. BMJ 353:i1777. https:\/\/doi.org\/10.1002\/14651858.CD010227.pub2","journal-title":"BMJ"},{"key":"5762_CR7","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1148\/rg.301095089","volume":"30","author":"JA Narvaez","year":"2010","unstructured":"Narvaez JA, Narvaez J, De LE, De AM (2010) MR imaging of early rheumatoid arthritis. Radiographics 30:143\u2013163. https:\/\/doi.org\/10.1148\/rg.301095089","journal-title":"Radiographics"},{"key":"5762_CR8","first-page":"2485","volume":"32","author":"RJ Wakefield","year":"2005","unstructured":"Wakefield RJ, Balint PV, Szkudlarek M, Filippucci E, Backhaus M, DA MA et al (2005) Musculoskeletal ultrasound including definitions for ultrasonographic pathology. J Rheumatol 32:2485\u20132487. https:\/\/pubmed.ncbi.nlm.nih.gov\/16331793\/","journal-title":"J Rheumatol"},{"key":"5762_CR9","doi-asserted-by":"publisher","first-page":"2762","DOI":"10.1002\/1529-0131(200012)43","volume":"43","author":"RJ Wakefield","year":"2000","unstructured":"Wakefield RJ, Gibbon WW, Conaghan PG, O\u2019Connor P, McGonagle D, Pease C et al (2000) The value of sonography in the detection of bone erosions in patients with rheumatoid arthritis: a comparison with conventional radiography. Arthritis Rheum 43:2762\u20132770. https:\/\/doi.org\/10.1002\/1529-0131(200012)43:12%3C2762::AID-ANR16%3E3.0.CO;2-%23","journal-title":"Arthritis Rheum"},{"key":"5762_CR10","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/j.berh.2008.09.014","volume":"22","author":"M Ostergaard","year":"2008","unstructured":"Ostergaard M, Pedersen SJ, Dohn UM (2008) Imaging in rheumatoid arthritis\u2013status and recent advances for magnetic resonance imaging, ultrasonography, computed tomography and conventional radiography. Best Pract Res Clin Rheumatol 22:1019\u20131044. https:\/\/doi.org\/10.1016\/j.berh.2008.09.014","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"5762_CR11","doi-asserted-by":"publisher","first-page":"i4205","DOI":"10.1136\/bmj.i4205","volume":"354","author":"EA Haavardsholm","year":"2016","unstructured":"Haavardsholm EA, Aga AB, Olsen IC, Lillegraven S, Hammer HB, Uhlig T et al (2016) Ultrasound in management of rheumatoid arthritis: ARCTIC randomised controlled strategy trial. BMJ 354:i4205. https:\/\/doi.org\/10.1136\/bmj.i4205","journal-title":"BMJ"},{"key":"5762_CR12","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1136\/annrheumdis-2012-203158","volume":"72","author":"AN Colebatch","year":"2013","unstructured":"Colebatch AN, Edwards CJ, Ostergaard M, van der Heijde D, Balint PV, D\u2019Agostino MA et al (2013) EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis. Ann Rheum Dis 72:804\u2013814. https:\/\/doi.org\/10.1136\/annrheumdis-2012-203158","journal-title":"Ann Rheum Dis"},{"key":"5762_CR13","doi-asserted-by":"publisher","first-page":"R110","DOI":"10.1186\/ar1995","volume":"8","author":"UM Dohn","year":"2006","unstructured":"Dohn UM, Ejbjerg BJ, Court-Payen, Hasselquist M, Narvestad E, Szkudlarek M et al (2006) Are bone erosions detected by magnetic resonance imaging and ultrasonography true erosions? A comparison with computed tomography in rheumatoid arthritis metacarpophalangeal joints. Arthritis Res Ther 8:R110. https:\/\/doi.org\/10.1186\/ar1995","journal-title":"Arthritis Res Ther"},{"key":"5762_CR14","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/s13075-019-2000-1","volume":"21","author":"PG Conaghan","year":"2019","unstructured":"Conaghan PG, Ostergaard M, Troum O, Bowes MA, Guillard G, Wilkinson B et al (2019) Very early MRI responses to therapy as a predictor of later radiographic progression in early rheumatoid arthritis. Arthritis Res Ther 21:214. https:\/\/doi.org\/10.1186\/s13075-019-2000-1","journal-title":"Arthritis Res Ther"},{"key":"5762_CR15","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1001\/jama.2018.21362","volume":"321","author":"S M\u00f8ller-Bisgaard","year":"2019","unstructured":"M\u00f8ller-Bisgaard S, H\u00f8rslev-Petersen K, Ejbjerg B, Hetland ML, \u00d8rnbjerg LM, Glinatsi D et al (2019) Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial. JAMA 321:461\u2013472. https:\/\/doi.org\/10.1001\/jama.2018.21362","journal-title":"JAMA"},{"key":"5762_CR16","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1111\/1756-185x.13659","volume":"22","author":"Z Tuna","year":"2019","unstructured":"Tuna Z, Mete O, Tore G, Baglan Yentur S, Varan O, Goker B et al (2019) Validity of the Patient-Rated Wrist Evaluation questionnaire in rheumatoid arthritis. Int J Rheum Dis 22:1714\u20131718. https:\/\/doi.org\/10.1111\/1756-185x.13659","journal-title":"Int J Rheum Dis"},{"key":"5762_CR17","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1186\/s12891-016-1246-x","volume":"17","author":"AK Romero-Guzman","year":"2016","unstructured":"Romero-Guzman AK, Menchaca-Tapia VM, Contreras-Yanez I, Pascual-Ramos V (2016) Patient and physician perspectives of hand function in a cohort of rheumatoid arthritis patients: the impact of disease activity. BMC Musculoskelet Disord 17:392. https:\/\/doi.org\/10.1186\/s12891-016-1246-x","journal-title":"BMC Musculoskelet Disord"},{"key":"5762_CR18","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.rdc.2016.01.010","volume":"42","author":"LH van Tuyl","year":"2016","unstructured":"van Tuyl LH, Michaud K (2016) Patient-Reported Outcomes in Rheumatoid Arthritis. Rheum Dis Clin North Am 42:219\u2013237. https:\/\/doi.org\/10.1016\/j.rdc.2016.01.010","journal-title":"Rheum Dis Clin North Am"},{"key":"5762_CR19","doi-asserted-by":"publisher","unstructured":"Logstrup BB, Masic D, Laurbjerg TB, Blegvad J, Herly M, Kristensen LD et al Left ventricular function at two-year follow-up in treatment-naive rheumatoid arthritis patients is associated with anti-cyclic citrullinated peptide antibody status: a cohort study. Scand J Rheumatol 2017:1\u20139. https:\/\/doi.org\/10.1080\/03009742.2016.1249941","DOI":"10.1080\/03009742.2016.1249941"},{"key":"5762_CR20","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.3899\/jrheum.181095","volume":"46","author":"GA Bruyn","year":"2019","unstructured":"Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB et al (2019) OMERACT Definitions for Ultrasonographic Pathologies and Elementary Lesions of Rheumatic Disorders 15 Years On. J Rheumatol 46:1388\u20131393. https:\/\/doi.org\/10.3899\/jrheum.181095","journal-title":"J Rheumatol"},{"issue":"Suppl 1","key":"5762_CR21","doi-asserted-by":"publisher","first-page":"i3","DOI":"10.1136\/ard.2004.031773","volume":"64","author":"M Ostergaard","year":"2005","unstructured":"Ostergaard M, Edmonds J, McQueen F, Peterfy C, Lassere M, Ejbjerg B et al (2005) An introduction to the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas. Ann Rheum Dis 64(Suppl 1):i3\u2013i7. https:\/\/doi.org\/10.1136\/ard.2004.031773","journal-title":"Ann Rheum Dis"},{"key":"5762_CR22","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.jclinepi.2010.03.002","volume":"64","author":"J Kottner","year":"2011","unstructured":"Kottner J, Audige L, Brorson S, Donner A, Gajewski BJ, Hrobjartsson A et al (2011) Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed. J Clin Epidemiol 64:96\u2013106. https:\/\/doi.org\/10.1016\/j.jclinepi.2010.03.002","journal-title":"J Clin Epidemiol"},{"key":"5762_CR23","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1097\/bor.0000000000000282","volume":"28","author":"AJ Mathew","year":"2016","unstructured":"Mathew AJ, Danda D, Conaghan PG (2016) MRI and ultrasound in rheumatoid arthritis. Curr Opin Rheumatol 28:323\u2013329. https:\/\/doi.org\/10.1097\/bor.0000000000000282","journal-title":"Curr Opin Rheumatol"},{"key":"5762_CR24","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1002\/art.37848","volume":"65","author":"D Nakagomi","year":"2013","unstructured":"Nakagomi D, Ikeda K, Okubo A, Iwamoto T, Sanayama Y, Takahashi K et al (2013) Ultrasound can improve the accuracy of the 2010 American College of Rheumatology\/European League against rheumatism classification criteria for rheumatoid arthritis to predict the requirement for methotrexate treatment. Arthritis Rheum 65:890\u2013898. https:\/\/doi.org\/10.1002\/art.37848","journal-title":"Arthritis Rheum"},{"key":"5762_CR25","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1136\/annrheumdis-2013-204005","volume":"74","author":"A Krabben","year":"2015","unstructured":"Krabben A, Stomp W, Huizinga TW, van der Heijde D, Bloem JL, Reijnierse M et al (2015) Concordance between inflammation at physical examination and on MRI in patients with early arthritis. Ann Rheum Dis 74:506\u2013512. https:\/\/doi.org\/10.1136\/annrheumdis-2013-204005","journal-title":"Ann Rheum Dis"},{"key":"5762_CR26","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s00256-019-03179-z","volume":"48","author":"DA Rubin","year":"2019","unstructured":"Rubin DA (2019) MRI and ultrasound of the hands and wrists in rheumatoid arthritis. I. Imaging findings. Skeletal Radiol 48:677\u2013695. https:\/\/doi.org\/10.1007\/s00256-019-03179-z","journal-title":"Skeletal Radiol"},{"key":"5762_CR27","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.rdc.2022.02.010","volume":"48","author":"JJ Cush","year":"2022","unstructured":"Cush JJ (2022) Rheumatoid Arthritis: Early Diagnosis and Treatment. Rheum Dis Clin North Am 48:537\u2013547. https:\/\/doi.org\/10.1016\/j.rdc.2022.02.010","journal-title":"Rheum Dis Clin North Am"},{"key":"5762_CR28","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1111\/1756-185x.12448","volume":"19","author":"LC Chew","year":"2016","unstructured":"Chew LC, Chandra Mohan P, Chan LP, Fong KY, Thumboo J (2016) Use of magnetic resonance imaging in detecting subclinical synovitis in rheumatoid arthritis and correlation of imaging findings with interleukin-18 levels. Int J Rheum Dis 19:790\u2013798. https:\/\/doi.org\/10.1111\/1756-185x.12448","journal-title":"Int J Rheum Dis"},{"key":"5762_CR29","unstructured":"Goupille P, Roulot B, Akoka S, Avimadje AM, Garaud P, Naccache L et al (2001) Magnetic resonance imaging: a valuable method for the detection of synovial inflammation in rheumatoid arthritis. J Rheumatol. 28:35\u201340. https:\/\/pubmed.ncbi.nlm.nih.gov\/11196540\/"},{"key":"5762_CR30","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.ejrad.2009.04.048","volume":"71","author":"M Boesen","year":"2009","unstructured":"Boesen M, Ostergaard M, Cimmino MA, Kubassova O, Jensen KE, Bliddal H (2009) MRI quantification of rheumatoid arthritis: current knowledge and future perspectives. Eur J Radiol 71:189\u2013196. https:\/\/doi.org\/10.1016\/j.ejrad.2009.04.048","journal-title":"Eur J Radiol"},{"key":"5762_CR31","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1111\/j.1749-6632.2009.04382.x","volume":"1154","author":"FM McQueen","year":"2009","unstructured":"McQueen FM (2009) The MRI view of synovitis and tenosynovitis in inflammatory arthritis: implications for diagnosis and management. Ann N Y Acad Sci 1154:21\u201334. https:\/\/doi.org\/10.1111\/j.1749-6632.2009.04382.x","journal-title":"Ann N Y Acad Sci"},{"key":"5762_CR32","doi-asserted-by":"publisher","first-page":"e000427","DOI":"10.1136\/rmdopen-2016-000427","volume":"3","author":"L Terslev","year":"2017","unstructured":"Terslev L, Naredo E, Aegerter P, Wakefield RJ, Backhaus M, Balint P et al (2017) Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system. RMD Open 3:e000427. https:\/\/doi.org\/10.1136\/rmdopen-2016-000427","journal-title":"RMD Open"},{"key":"5762_CR33","doi-asserted-by":"publisher","first-page":"e000428","DOI":"10.1136\/rmdopen-2016-000428","volume":"3","author":"MA D\u2019Agostino","year":"2017","unstructured":"D\u2019Agostino MA, Terslev L, Aegerter P, Backhaus M, Balint P, Bruyn GA et al (2017) Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 1: definition and development of a standardised, consensus-based scoring system. RMD Open 3:e000428. https:\/\/doi.org\/10.1136\/rmdopen-2016-000428","journal-title":"RMD Open"},{"key":"5762_CR34","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1007\/s003300000650","volume":"11","author":"N Magarelli","year":"2001","unstructured":"Magarelli N, Guglielmi G, Di Matteo L, Tartaro A, Mattei PA, Bonomo L (2001) Diagnostic utility of an echo-contrast agent in patients with synovitis using power Doppler ultrasound: a preliminary study with comparison to contrast-enhanced MRI. Eur Radiol 11:1039\u20131046. https:\/\/doi.org\/10.1007\/s003300000650","journal-title":"Eur Radiol"},{"key":"5762_CR35","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1093\/rheumatology\/kex036","volume":"57","author":"K Takase-Minegishi","year":"2018","unstructured":"Takase-Minegishi K, Horita N, Kobayashi K, Yoshimi R, Kirino Y, Ohno S et al (2018) Diagnostic test accuracy of ultrasound for synovitis in rheumatoid arthritis: systematic review and meta-analysis. Rheumatology (Oxford) 57:49\u201358. https:\/\/doi.org\/10.1093\/rheumatology\/kex036","journal-title":"Rheumatology (Oxford)"},{"key":"5762_CR36","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s13075-019-1824-z","volume":"21","author":"S Ohrndorf","year":"2019","unstructured":"Ohrndorf S, Boer AC, Boeters DM, Ten Brinck RM, Burmester GR, Kortekaas MC et al (2019) Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia. Arthritis Res Ther 21:59. https:\/\/doi.org\/10.1186\/s13075-019-1824-z","journal-title":"Arthritis Res Ther"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-024-05762-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00296-024-05762-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-024-05762-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T06:38:21Z","timestamp":1737700701000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00296-024-05762-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,14]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["5762"],"URL":"https:\/\/doi.org\/10.1007\/s00296-024-05762-7","relation":{},"ISSN":["1437-160X"],"issn-type":[{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,14]]},"assertion":[{"value":"2 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All patients provided written informed consent following the principles of the Declaration of Helsinki and the study was approved by the local ethics committee (Approved by the regional scientific ethical committee: ESDH 1-10-72-251-12, June 2nd 2010, De Videnskabsetiske Komit\u00e9er, Region Midtjylland, Denmark).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The content of the manuscript has not been presented elsewhere at any time","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Previous presentation"}}],"article-number":"1"}}