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This prospective pre-post feasibility study aimed to explore the feasibility and acceptability of a six-week home-based stretching intervention for people with fibromyalgia. People aged 18\u201355 years diagnosed with fibromyalgia were eligible for participation. Participants were offered a home-based stretching intervention with weekly follow-up via a mHealth app. Semi-structured online focus group interviews were conducted to gain insight into the participants\u2019 experience and acceptance of the intervention. Quantitative assessments included the Revised Fibromyalgia Impact Questionnaire, the SF-36, pressure pain thresholds, range of motion, and self-reported adherence. 12 females were recruited over 43 days. One participant withdrew from the study due to illness. The adherence rate was high. Four major themes emerged from the interviews: (1) Factors motivating participation, (2) The advantages of exercising at home, (3) Influence of weekly communication and (4) Potential areas for improvement. Qualitative findings suggest that the intervention was well tolerated and easily implemented in daily life. There were clinically relevant improvements in health-related quality of life, physical health, and mental health scores. A six-week home-based stretching program, supervised via an mHealth application, proved feasible and acceptable for individuals with FM and showed promising clinical outcomes. Based on insights from this feasibility study, an RCT is planned to evaluate whether the program of home-based stretching exercises provides greater benefits than usual care alone in enhancing quality of life and functional outcomes in patients with FM.\n                    <jats:italic>Trial registration number<\/jats:italic>\n                    : NCT06176053. Date of registration: 12\/08\/2023.\n                  <\/jats:p>","DOI":"10.1007\/s00296-025-05921-4","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T11:55:12Z","timestamp":1754913312000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Exploring the feasibility, acceptability and preliminary efficacy of a Home-Based stretching program for adults with fibromyalgia: a prospective Pre-Post feasibility study"],"prefix":"10.1007","volume":"45","clinical-trial-number":[{"clinical-trial-number":"nct0617605","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6010-4376","authenticated-orcid":false,"given":"Morten Pallisgaard","family":"St\u00f8ve","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise Landbo","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stig Peter","family":"Magnusson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janus Laust","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Riis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"5921_CR1","doi-asserted-by":"publisher","unstructured":"Queiroz LP (2013) Worldwide epidemiology of fibromyalgia topical collection on fibromyalgia. 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Pain 152:2470\u20132476. https:\/\/doi.org\/10.1016\/j.pain.2011.05.027","journal-title":"Pain"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-025-05921-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00296-025-05921-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-025-05921-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:14:57Z","timestamp":1760523297000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00296-025-05921-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,11]]},"references-count":50,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,9]]}},"alternative-id":["5921"],"URL":"https:\/\/doi.org\/10.1007\/s00296-025-05921-4","relation":{},"ISSN":["1437-160X"],"issn-type":[{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,11]]},"assertion":[{"value":"29 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Participants provided written informed consent to participate in the study. The trial was reported to the Danish Data Protection Agency, registered at ClinicalTrials.gov (Trial registration number NCT06176053), and approved by the North Denmark Region Committee on Health Research Ethics (N-20230056), Case number 2023-038746-7, date 14-12-2023. The study complied with the relevant national regulations and institutional policies and followed the tenets of the Helsinki Declaration. Participants provided written informed consent before participation.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable. Some of the findings have been presented as a conference abstract titled: \u201cExploring the feasibility and acceptability of performing a home-based stretching intervention in people with fibromyalgia\u201d at the World Physiotherapy Congress 2025. The abstract is not publicly available.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"191"}}