{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T16:23:43Z","timestamp":1762273423583,"version":"build-2065373602"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>This study aimed to identify risk factors of nociplastic pain in patients with autoimmune arthritis. Patients suffering from chronic pain and autoimmune arthritis were invited to participate in a study via moderated support groups on social media. Each invitation included a brief description of nociplastic pain. The study cohort comprised 185 patients, primarily those with rheumatoid arthritis (64%) and spondyloarthropathies (27%). 82% of patients scored positively (\u2265\u200940 points) on the Central Sensitization Inventory (CSI), while 57% showed a neuropathic component as indicated by the PainDetect Questionnaire (PDQ). Of the participants with a positive CSI score, 86% achieved at least a borderline grade on the PDQ. More frequent use of painkillers (&gt;\u2009once a day) correlated with higher CSI scores (mean difference (MD)\u2009=\u20097.1, <jats:italic>p<\/jats:italic>\u2009=\u20090.039, and MD\u2009=\u20098, <jats:italic>p<\/jats:italic>\u2009=\u20090.005 compared to daily and less frequent use, respectively). In a multivariable linear regression model, factors such as depression (\u03b2\u2009=\u20098.7, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), nocturnal pain (\u03b2\u2009=\u20094.5, <jats:italic>p<\/jats:italic>\u2009=\u20090.013), need for painkillers (\u03b2\u2009=\u20095.3, <jats:italic>p<\/jats:italic>\u2009=\u20090.032), disease duration\u2009&gt;\u20092 years (\u03b2\u2009=\u20093.3, <jats:italic>p<\/jats:italic>\u2009=\u20090.036), Chronic Pain Grade Scale (\u03b2\u2009=\u20092.8, from I to IV grade, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and worse mood (\u03b2 = -0.9, on a 0\u201310 scale, <jats:italic>p<\/jats:italic>\u2009=\u20090.031) were independently associated with higher CSI scores. Nocturnal pain and pain-related disability may serve as clinical risk factors of nociplastic pain. The PDQ may lose its reliability in detecting neuropathic pain in patients with a high nociplastic component.<\/jats:p>","DOI":"10.1007\/s00296-025-05948-7","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T04:44:04Z","timestamp":1755837844000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Risk factors of nociplastic pain in patients with autoimmune arthritis: web-based cross-sectional survey of patients"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4621-6247","authenticated-orcid":false,"given":"Grzegorz","family":"Mirocha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2036-375X","authenticated-orcid":false,"given":"Joanna","family":"Makowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3885-8497","authenticated-orcid":false,"given":"Olga","family":"Brzezi\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,22]]},"reference":[{"key":"5948_CR1","doi-asserted-by":"publisher","unstructured":"Baron R, Binder A, Wasner G (2010) Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment. 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