{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:51:05Z","timestamp":1780501865619,"version":"3.54.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"DOI":"10.1007\/s00296-025-06007-x","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T04:54:43Z","timestamp":1761195283000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of gastrointestinal involvement on mortality and malnutrition in systemic sclerosis: an observational cohort of 135 patients"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2605-7038","authenticated-orcid":false,"given":"Marie","family":"Bader","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achille","family":"Aouba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2924-8029","authenticated-orcid":false,"given":"R\u00e9my","family":"Morello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Boutemy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Martin Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8887-3233","authenticated-orcid":false,"given":"Samuel","family":"Deshayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gw\u00e9nola","family":"Maign\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9915-8451","authenticated-orcid":false,"given":"Sophie","family":"Gallou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0797-9170","authenticated-orcid":false,"given":"R\u00e9mi","family":"Philip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9083-8365","authenticated-orcid":false,"given":"Hubert","family":"de Boysson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1105-7662","authenticated-orcid":false,"given":"Ana\u00ebl","family":"Dumont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"issue":"1","key":"6007_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2021.104087","volume":"50","author":"B Thoreau","year":"2021","unstructured":"Thoreau B, Chaigne B, Renaud A, Mouthon L (2021) Pathophysiology of systemic sclerosis. Presse Med 50(1):104087. https:\/\/doi.org\/10.1016\/j.lpm.2021.104087","journal-title":"Presse Med"},{"issue":"3","key":"6007_CR2","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1172\/JCI31139","volume":"117","author":"J Varga","year":"2007","unstructured":"Varga J, Abraham D (2007) Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 117(3):557\u2013567. https:\/\/doi.org\/10.1172\/JCI31139","journal-title":"J Clin Invest"},{"issue":"1","key":"6007_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.2","volume":"1","author":"Y Allanore","year":"2015","unstructured":"Allanore Y, Simms R, Distler O, Trojanowska M, Pope J, Denton CP, Varga John (2015) Systemic sclerosis. Nat Rev Dis Primers 1(1):15002. https:\/\/doi.org\/10.1038\/nrdp.2015.2","journal-title":"Nat Rev Dis Primers"},{"key":"6007_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2023.109267","volume":"248","author":"J Tian","year":"2023","unstructured":"Tian J, Kang S, Zhang D, Huang Y, Zhao M, Gui X et al (2023) Global, regional, and national incidence and prevalence of systemic sclerosis. Clin Immunol 248:109267. https:\/\/doi.org\/10.1016\/j.clim.2023.109267","journal-title":"Clin Immunol"},{"key":"6007_CR5","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.semarthrit.2007.05.003","volume":"37","author":"H Chifflot","year":"2008","unstructured":"Chifflot H, Fautrel B, Sordet C, Chatelus E, Sibilia J (2008) Incidence and prevalence of systemic sclerosis: a systematic literature review. Semin Arthritis Rheum 37:223\u2013235. https:\/\/doi.org\/10.1016\/j.semarthrit.2007.05.003","journal-title":"Semin Arthritis Rheum"},{"issue":"7","key":"6007_CR6","first-page":"1573","volume":"28","author":"EC LeROY Jr","year":"2001","unstructured":"LeROY EC Jr (2001) Criteria for the classification of early systemic sclerosis. J Rheumatol 28(7):1573\u20131576","journal-title":"J Rheumatol"},{"key":"6007_CR7","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12016-010-8198-y","volume":"40","author":"E Hachulla","year":"2011","unstructured":"Hachulla E, Launay D (2011) Diagnosis and classification of systemic sclerosis. Clin Rev Allergy Immunol 40:78\u201383. https:\/\/doi.org\/10.1007\/s12016-010-8198-y","journal-title":"Clin Rev Allergy Immunol"},{"key":"6007_CR8","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1002\/art.41153","volume":"72","author":"SI Nihtyanova","year":"2020","unstructured":"Nihtyanova SI, Sari A, Harvey JC, Leslie A, Derrett-Smith EC, Fonseca C et al (2020) Using autoantibodies and cutaneous subset to develop outcome-based disease classification in systemic sclerosis. Arthritis Rheumatol 72:465\u2013476. https:\/\/doi.org\/10.1002\/art.41153","journal-title":"Arthritis Rheumatol"},{"key":"6007_CR9","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1002\/art.1780370902","volume":"37","author":"RW Sjogren","year":"1994","unstructured":"Sjogren RW (1994) Gastrointestinal motility disorders in scleroderma. Arthritis Rheum 37:1265\u20131282. https:\/\/doi.org\/10.1002\/art.1780370902","journal-title":"Arthritis Rheum"},{"key":"6007_CR10","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/0002-9343(69)90044-8","volume":"46","author":"WA D\u2019Angelo","year":"1969","unstructured":"D\u2019Angelo WA, Fries JF, Masi. AT, Shulman LE (1969) Pathologic observations in systemic sclerosis (scleroderma). Am J Med 46:428\u2013440. https:\/\/doi.org\/10.1016\/0002-9343(69)90044-8","journal-title":"Am J Med"},{"key":"6007_CR11","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1056\/NEJM197312062892304","volume":"289","author":"AJ DiMarino","year":"1973","unstructured":"DiMarino AJ, Carlson G, Myers A, Schumacher HR, Cohen S (1973) Duodenal myoelectric activity in scleroderma: abnormal responses to mechanical and hormonal stimuli. N Engl J Med 289:1220\u20131223. https:\/\/doi.org\/10.1056\/NEJM197312062892304","journal-title":"N Engl J Med"},{"key":"6007_CR12","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.1016\/S0755-4982(06)74930-2","volume":"35","author":"I Marie","year":"2006","unstructured":"Marie I (2006) Atteinte digestive Au cours de La scl\u00e9rodermie syst\u00e9mique. Presse Med 35:1952\u20131965. https:\/\/doi.org\/10.1016\/S0755-4982(06)74930-2","journal-title":"Presse Med"},{"key":"6007_CR13","doi-asserted-by":"publisher","first-page":"247","DOI":"10.5301\/jsrd.5000214","volume":"1","author":"AB Shreiner","year":"2016","unstructured":"Shreiner AB, Murray C, Denton C, Khanna D (2016) Gastrointestinal manifestations of systemic sclerosis. Journal of Scleroderma and Related Disorders 1:247\u2013256. https:\/\/doi.org\/10.5301\/jsrd.5000214","journal-title":"Journal of Scleroderma and Related Disorders"},{"key":"6007_CR14","doi-asserted-by":"publisher","first-page":"iii36","DOI":"10.1093\/rheumatology\/ken485","volume":"48","author":"A Forbes","year":"2009","unstructured":"Forbes A, Marie I (2009) Gastrointestinal complications: the most frequent internal complications of systemic sclerosis. Rheumatology (Oxford) 48:iii36\u2013iii39. https:\/\/doi.org\/10.1093\/rheumatology\/ken485","journal-title":"Rheumatology (Oxford)"},{"key":"6007_CR15","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/j.revmed.2023.05.003","volume":"44","author":"A Renaud","year":"2023","unstructured":"Renaud A, Jirka A, Durant C, Connault J, Espitia O, Takoudju C et al (2023) Atteinte digestive de La scl\u00e9rodermie syst\u00e9mique. Rev Med Interne 44:410\u2013422. https:\/\/doi.org\/10.1016\/j.revmed.2023.05.003","journal-title":"Rev Med Interne"},{"key":"6007_CR16","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/0049-0172(94)90097-3","volume":"24","author":"M Abu-Shakra","year":"1994","unstructured":"Abu-Shakra M, Guillemin F, Lee P (1994) Gastrointestinal manifestations of systemic sclerosis. Semin Arthritis Rheum 24:29\u201339. https:\/\/doi.org\/10.1016\/0049-0172(94)90097-3","journal-title":"Semin Arthritis Rheum"},{"key":"6007_CR17","doi-asserted-by":"publisher","first-page":"2437","DOI":"10.1002\/1529-0131(200011)43:11<2437::AID-ANR10>3.0.CO;2-U","volume":"43","author":"VD Steen","year":"2000","unstructured":"Steen VD, Medsger TA (2000) Severe organ involvement in systemic sclerosis with diffuse scleroderma. Arthritis Rheum 43:2437\u20132444. https:\/\/doi.org\/10.1002\/1529-0131(200011)43:11%3C2437::AID-ANR10%3E3.0.CO;2-U","journal-title":"Arthritis Rheum"},{"key":"6007_CR18","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.3899\/jrheum.090694","volume":"36","author":"M Baron","year":"2009","unstructured":"Baron M, Hudson M, Steele R (2009) Malnutrition is common in systemic sclerosis: results from the Canadian scleroderma research group database. J Rheumatol 36:2737\u20132743. https:\/\/doi.org\/10.3899\/jrheum.090694","journal-title":"J Rheumatol"},{"key":"6007_CR19","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.1093\/rheumatology\/keq147","volume":"49","author":"NM Thoua","year":"2010","unstructured":"Thoua NM, Bunce C, Brough G, Forbes A, Emmanuel AV, Denton CP (2010) Assessment of gastrointestinal symptoms in patients with systemic sclerosis in a UK tertiary referral centre. Rheumatology (Oxford) 49:1770\u20131775. https:\/\/doi.org\/10.1093\/rheumatology\/keq147","journal-title":"Rheumatology (Oxford)"},{"key":"6007_CR20","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1136\/ard.2009.114264","volume":"69","author":"AJ Tyndall","year":"2010","unstructured":"Tyndall AJ, Bannert B, Vonk M, Airo P, Cozzi F, Carreira PE et al (2010) Causes and risk factors for death in systemic sclerosis: a study from the EULAR scleroderma trials and research (EUSTAR) database. Ann Rheum Dis 69:1809\u20131815. https:\/\/doi.org\/10.1136\/ard.2009.114264","journal-title":"Ann Rheum Dis"},{"issue":"7","key":"6007_CR21","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1007\/s00296-021-04806-6","volume":"41","author":"J Bering","year":"2021","unstructured":"Bering J, Griffing WL, Crowell M, Umar SB (2021) Progression of gastrointestinal symptoms over time in patients with systemic sclerosis. Rheumatol Int 41(7):1281\u20131287. https:\/\/doi.org\/10.1007\/s00296-021-04806-6","journal-title":"Rheumatol Int"},{"key":"6007_CR22","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1002\/acr.23479","volume":"70","author":"ZH McMahan","year":"2018","unstructured":"McMahan ZH, Paik JJ, Wigley FM, Hummers LK (2018) Determining the risk factors and clinical features associated with severe gastrointestinal dysmotility in systemic sclerosis. Arthritis Care Res 70:1385\u20131392. https:\/\/doi.org\/10.1002\/acr.23479","journal-title":"Arthritis Care Res"},{"key":"6007_CR23","doi-asserted-by":"publisher","first-page":"132","DOI":"10.20452\/pamw.907","volume":"120","author":"E Wielosz","year":"2010","unstructured":"Wielosz E, Borys O, \u017bychowska I, Majdan M (2010) Gastrointestinal involvement in patients with systemic sclerosis. Pol Arch Intern Med 120:132\u2013136. https:\/\/doi.org\/10.20452\/pamw.907","journal-title":"Pol Arch Intern Med"},{"key":"6007_CR24","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/j.autrev.2018.02.008","volume":"17","author":"S Panopoulos","year":"2018","unstructured":"Panopoulos S, Bournia VK, Konstantonis G, Fragiadaki K, Sfikakis PP, Tektonidou MG (2018) Predictors of morbidity and mortality in early systemic sclerosis: long-term follow-up data from a single-centre inception cohort. Autoimmun Rev 17:816\u2013820. https:\/\/doi.org\/10.1016\/j.autrev.2018.02.008","journal-title":"Autoimmun Rev"},{"key":"6007_CR25","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-015-0176-2","volume":"4","author":"BY Hong","year":"2015","unstructured":"Hong BY, Giang R, Mbuagbaw L, Larche M, Thabane L (2015) Factors associated with development of gastrointestinal problems in patients with scleroderma: a systematic review. Syst Rev 4:188. https:\/\/doi.org\/10.1186\/s13643-015-0176-2","journal-title":"Syst Rev"},{"key":"6007_CR26","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.1002\/art.38098","volume":"65","author":"F Van Den Hoogen","year":"2013","unstructured":"Van Den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A et al (2013) 2013 classification criteria for systemic sclerosis: an American college of rheumatology\/European league against rheumatism collaborative initiative. Arthritis Rheum 65:2737\u20132747. https:\/\/doi.org\/10.1002\/art.38098","journal-title":"Arthritis Rheum"},{"key":"6007_CR27","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1093\/rheumatology\/keu530","volume":"54","author":"S Jordan","year":"2015","unstructured":"Jordan S, Maurer B, Toniolo M, Michel B, Distler O (2015) Performance of the new ACR\/EULAR classification criteria for systemic sclerosis in clinical practice. Rheumatology (Oxford) 54:1454\u20131458. https:\/\/doi.org\/10.1093\/rheumatology\/keu530","journal-title":"Rheumatology (Oxford)"},{"key":"6007_CR28","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1017\/S0007114521001471","volume":"127","author":"J Delarue","year":"2022","unstructured":"Delarue J, Desport JC, Dubern B, Joly F, Mas E, Pitard A et al (2022) Diagnosing undernutrition children and adults: new French criteria. Why, for what and for whom? A joint statement of the French National authority for health and French federation of nutrition. Br J Nutr 127:739\u2013751. https:\/\/doi.org\/10.1017\/S0007114521001471","journal-title":"Br J Nutr"},{"key":"6007_CR29","unstructured":"Nishimagi E, Tochimoto A, Kawaguchi Y, Satoh T, Kuwana M, Takagi K et al (2007) Characteristics of patients with early systemic sclerosis and severe Gastrointestinal tract involvement. J Rheumatol 2007 Oct;34(10):2050-5."},{"key":"6007_CR30","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.semarthrit.2005.03.005","volume":"35","author":"VD Steen","year":"2005","unstructured":"Steen VD (2005) Autoantibodies in systemic sclerosis. Semin Arthritis Rheum 35:35\u201342. https:\/\/doi.org\/10.1016\/j.semarthrit.2005.03.005","journal-title":"Semin Arthritis Rheum"},{"key":"6007_CR31","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.3899\/jrheum.131547","volume":"41","author":"C Mecoli","year":"2014","unstructured":"Mecoli C, Purohit S, Sandorfi N, Derk CT (2014) Mortality, recurrence, and hospital course of patients with systemic sclerosis-related acute intestinal pseudo-obstruction. J Rheumatol 41:2049\u20132054. https:\/\/doi.org\/10.3899\/jrheum.131547","journal-title":"J Rheumatol"},{"key":"6007_CR32","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1002\/acr.23763","volume":"71","author":"ZH McMahan","year":"2019","unstructured":"McMahan ZH, Domsic RT, Zhu L, Medsger TA, Casciola-Rosen L, Shah AA (2019) Anti-RNPC3 (U11\/U12) antibodies in systemic sclerosis are associated with moderate to severe Gastrointestinal dysmotility. Arthritis Care Res 71:1164\u20131170. https:\/\/doi.org\/10.1002\/acr.23763","journal-title":"Arthritis Care Res"},{"key":"6007_CR33","first-page":"S190","volume":"33","author":"V Codullo","year":"2015","unstructured":"Codullo V, Cereda E, Crepaldi G, Cappello S, Montecucco C, Caccialanza R et al (2015) Disease-related malnutrition in systemic sclerosis: evidences and implications. Clin Exp Rheumatol 33:S190\u2013194","journal-title":"Clin Exp Rheumatol"},{"key":"6007_CR34","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.clnu.2013.08.010","volume":"33","author":"E Cereda","year":"2014","unstructured":"Cereda E, Codullo V, Klersy C, Breda S, Crippa A, Rava ML et al (2014) Disease-related nutritional risk and mortality in systemic sclerosis. Clin Nutr 33:558\u2013561. https:\/\/doi.org\/10.1016\/j.clnu.2013.08.010","journal-title":"Clin Nutr"},{"key":"6007_CR35","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1016\/j.autrev.2018.05.010","volume":"17","author":"R Dupont","year":"2018","unstructured":"Dupont R, Longu\u00e9 M, Galinier A, Cinq Frais C, Ingueneau C, Astudillo L et al (2018) Impact of micronutrient deficiency & malnutrition in systemic sclerosis: cohort study and literature review. Autoimmun Rev 17:1081\u20131089. https:\/\/doi.org\/10.1016\/j.autrev.2018.05.010","journal-title":"Autoimmun Rev"},{"key":"6007_CR36","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1136\/ard.2009.123273","volume":"69","author":"L Krause","year":"2010","unstructured":"Krause L, Becker MO, Brueckner CS, Bellinghausen CJ, Becker C, Schneider U et al (2010) Nutritional status as marker for disease activity and severity predicting mortality in patients with systemic sclerosis. Ann Rheum Dis 69:1951\u20131957. https:\/\/doi.org\/10.1136\/ard.2009.123273","journal-title":"Ann Rheum Dis"},{"key":"6007_CR37","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0261-5614(03)00098-0","volume":"22","author":"J Kondrup","year":"2003","unstructured":"Kondrup J (2003) ESPEN guidelines for nutrition screening 2002. Clin Nutr 22:415\u2013421. https:\/\/doi.org\/10.1016\/S0261-5614(03)00098-0","journal-title":"Clin Nutr"},{"issue":"3","key":"6007_CR38","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keae209","volume":"64","author":"JL Fairley","year":"2024","unstructured":"Fairley JL, Hansen D, Quinlivan A, Proudman S, Sahhar J, Ngian GS et al (2024) Frequency and implications of malnutrition in systemic sclerosis. Rheumatology (Oxford) keae209. https:\/\/doi.org\/10.1093\/rheumatology\/keae209","journal-title":"Rheumatology (Oxford)"},{"issue":"1","key":"6007_CR39","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-024-05783-2","volume":"45","author":"N \u00d6z","year":"2025","unstructured":"\u00d6z N, Gezer HH, Karabulut Y, Duru\u00f6z MT (2025) Association of nutritional status indices with gastrointestinal symptoms in systemic sclerosis: a cross-sectional study. Rheumatol Int 45(1):21. https:\/\/doi.org\/10.1007\/s00296-024-05783-2","journal-title":"Rheumatol Int"},{"issue":"4","key":"6007_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00296-025-05830-6","volume":"45","author":"J Gajdecki","year":"2025","unstructured":"Gajdecki J, St\u0119pie\u0144 B, Gajdecka K, Brzezi\u0144ska O, Nadel A, Makowska J et al (2025) Controlling nutritional status score as a sensitive instrument for malnutrition screening in systemic sclerosis - a retrospective study. Rheumatol Int 45(4):1\u201310","journal-title":"Rheumatol Int"},{"key":"6007_CR41","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1136\/ard.60.6.592","volume":"60","author":"G Valentini","year":"2001","unstructured":"Valentini G (2001) European multicentre study to define disease activity criteria for systemic sclerosis. II. Identification of disease activity variables and development of preliminary activity indexes. Ann Rheum Dis 60:592\u2013598. https:\/\/doi.org\/10.1136\/ard.60.6.592","journal-title":"Ann Rheum Dis"},{"key":"6007_CR42","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1097\/00002281-200011000-00012","volume":"12","author":"TA Medsger","year":"2000","unstructured":"Medsger TA (2000) Assessment of damage and activity in systemic sclerosis. Curr Opin Rheumatol 12:545\u2013548. https:\/\/doi.org\/10.1097\/00002281-200011000-00012","journal-title":"Curr Opin Rheumatol"},{"key":"6007_CR43","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1097\/01.bor.0000434668.32150.e5","volume":"25","author":"D Khanna","year":"2013","unstructured":"Khanna D, Nagaraja V, Gladue H, Chey W, Pimentel M, Frech T (2013) Measuring response in the gastrointestinal tract in systemic sclerosis. Curr Opin Rheumatol 25:700\u2013706. https:\/\/doi.org\/10.1097\/01.bor.0000434668.32150.e5","journal-title":"Curr Opin Rheumatol"},{"key":"6007_CR44","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1002\/art.24730","volume":"61","author":"D Khanna","year":"2009","unstructured":"Khanna D, Hays RD, Maranian P, Seibold JR, Impens A, Mayes MD et al (2009) Reliability and validity of the University of California, Los Angeles scleroderma clinical trial consortium gastrointestinal tract instrument. Arthritis Care Res 61:1257\u20131263. https:\/\/doi.org\/10.1002\/art.24730","journal-title":"Arthritis Care Res"},{"key":"6007_CR45","unstructured":"Bae S, Allanore Y, Coustet B, Maranian P, Khanna D (2011) Development and validation of French version of the UCLA Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument. Clin Exp Rheumatol. 2011;29:S15-21"},{"key":"6007_CR46","doi-asserted-by":"publisher","unstructured":"Pope P J (2011) Measures of systemic sclerosis: HAQ and SHAQ, Physician- and patient related global Assessments, SBO, UCLA SCTC GIT 2.0, BDI, and TDI, CAMPHOR, RCS. Arthritis Care Res 63. https:\/\/doi.org\/10.1002\/acr.20598","DOI":"10.1002\/acr.20598"},{"key":"6007_CR47","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1136\/annrheumdis-2017-211448","volume":"76","author":"M Elhai","year":"2017","unstructured":"Elhai M, Meune C, Boubaya M, Avouac J, Hachulla E, Balbir-Gurman A et al (2017) Mapping and predicting mortality from systemic sclerosis. Ann Rheum Dis 76:1897\u20131905. https:\/\/doi.org\/10.1136\/annrheumdis-2017-211448","journal-title":"Ann Rheum Dis"},{"key":"6007_CR48","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1093\/rheumatology\/kev393","volume":"55","author":"A Valenzuela","year":"2016","unstructured":"Valenzuela A, Li S, Becker L, Fernandez-Becker N, Khanna D, Nguyen L, Chung Lorinda (2016) Intestinal pseudo-obstruction in patients with systemic sclerosis: an analysis of the nationwide inpatient sample. Rheumatology (Oxford) 55:654\u2013658. https:\/\/doi.org\/10.1093\/rheumatology\/kev393","journal-title":"Rheumatology (Oxford)"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-025-06007-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00296-025-06007-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-025-06007-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T05:12:50Z","timestamp":1763615570000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00296-025-06007-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,23]]},"references-count":48,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11]]}},"alternative-id":["6007"],"URL":"https:\/\/doi.org\/10.1007\/s00296-025-06007-x","relation":{},"ISSN":["1437-160X"],"issn-type":[{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,23]]},"assertion":[{"value":"30 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethics approval was obtained from the Local Research Ethics Committee (CLER) on July 17, 2025 (protocol number not assigned).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This descriptive, retrospective, non-interventional study was conducted in accordance with French public health regulations (Loi Jard\u00e9, Articles L1121-1 and L1122-1). Given the retrospective nature of the study and the use of existing data, written informed consent was not required by the ethics committee. All participants were informed of the study, and their right to oppose the use of their data was respected.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}],"article-number":"259"}}