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The Fimo Health App was developed to support patients with RA using a multidimensional approach combining educational modules, symptom tracking, and mind\u2013body exercises. This pilot feasibility study aimed to evaluate the usability, adherence, and potential clinical benefit of a prototype version of the app in patients with RA. A further objective was to explore patient subgroups that may particularly gain from the intervention. In a single-arm pilot trial, 31 patients with RA used the app over 12\u00a0weeks. Usability was assessed via the System Usability Scale (SUS). Primary clinical outcomes were patient-reported quality of life (SF-36 mental and SF-36 physical\u2009=\u2009Short-Form 36 Questionnaire), fatigue (FACIT-F), and pain (Visual Rating Scale Pain\u2009=\u2009VRS Pain), Secondary outcomes included functional impairment (HAQ\u2009=\u2009Health Assessment Questionnaire), global assessment, fear of motion (TSK\u2009=\u2009Tampa Scale of Kinesiophobia) and physical activity related-health competency (PAHCO). Subgroup analyses were conducted post hoc based on clinical characteristics. Usability was high (SUS\u2009=\u200974.4) and engagement with core app features strong (97% any use; 70% exercise completion). Across the full cohort (n\u2009=\u200931), changes in the primary outcomes were small overall. Physical quality of life (SF-36) showed a within-person median increase at 6\u00a0months (Hodges\u2013Lehmann \u0394\u2009=\u2009\u2009+\u20095.3; r\u2009=\u20090.50), while fatigue (FACIT-F) and pain (VRS) exhibited only small, non-significant numerical improvements (\u0394 \u2248\u2009+\u20091 to\u2009+\u20094; r \u2248 0.1\u20130.2). Mental quality of life (SF-36 mental) remained largely stable. In the subgroup of recently diagnosed patients (\u2264\u20092\u00a0years; n\u2009=\u200912), trends were more pronounced. Physical quality of life (SF-36 physical) improved consistently at 3 and 6\u00a0months (\u0394\u2009=\u2009\u2009+\u20091.3 to\u2009+\u20098.7;\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.67\u20130.85), accompanied by small favorable shifts in fatigue (\u0394 \u2248 \u20131.5 to\u2009+\u20092;\n                    <jats:italic>r<\/jats:italic>\n                    \u2248 0.2\u20130.3). Mental quality of life again (SF-36 mental) remained stable over time. The Fimo Health App is a usable and well-accepted digital intervention for patients with RA. Early diagnosed Patients showed signals of potential benefit.. These findings support the value of targeted digital tools early in the RA disease trajectory.\n                    <jats:italic>Trial Registration number<\/jats:italic>\n                    : DRKS00035194, registration date: 01.10.2024,\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/drks.de\/register\/de\/trial\/DRKS00035194\/preview\" ext-link-type=\"uri\">https:\/\/drks.de\/register\/de\/trial\/DRKS00035194\/preview<\/jats:ext-link>\n                    .\n                  <\/jats:p>","DOI":"10.1007\/s00296-025-06060-6","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T06:20:32Z","timestamp":1768026032000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluating usability, adherence and clinical benefit of a new digital heath application in rheumatoid arthritis: a pilot feasibility study"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4379-5121","authenticated-orcid":false,"given":"Valerie","family":"Schlaht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1397-6637","authenticated-orcid":false,"given":"Thomas","family":"Lenzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8725-1317","authenticated-orcid":false,"given":"Tim","family":"Fellerhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7098-7275","authenticated-orcid":false,"given":"Magdalena","family":"Binder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0739-1959","authenticated-orcid":false,"given":"Anna-Maria","family":"Liphardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5040-9643","authenticated-orcid":false,"given":"Sebastian","family":"Rudolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9828-3890","authenticated-orcid":false,"given":"Paloma","family":"Palm von Alten Blaskowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8740-9615","authenticated-orcid":false,"given":"Georg","family":"Schett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6688-2155","authenticated-orcid":false,"given":"Harriet","family":"Morf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,10]]},"reference":[{"key":"6060_CR1","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1056\/NEJMra1004965","volume":"365","author":"IB McInnes","year":"2011","unstructured":"McInnes IB, Schett G (2011) The pathogenesis of rheumatoid arthritis. 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