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Although Clinical Practice Guidelines for fibromyalgia currently exist, their application in diagnostic and therapeutic settings faces significant implementation challenges across healthcare systems. This has led to a persistent gap between knowledge and clinical practice, a phenomenon yet to be explored in the Danish context.\u00a0A cross-sectional study was conducted to investigate the level of knowledge and adherence to Clinical Practice Guidelines for fibromyalgia among Danish physical therapists, throughout a questionnaire consisting in the selection of the elements that they would consider for the adequate assessment, treatment, and expected duration of the therapeutic approach, to classify professionals as adherent, partially adherent, or non-adherent based on their selection of assessment and treatment components, and to evaluate their responses to 24 statements on a 5-point Likert scale reflecting their alignment with recommendations from Clinical Practice Guidelines.\u00a0A total of 149 physiotherapists (mean age 39.26 \u00b1 11.50, and gender-balanced) participated, amongst which 35 (23.49%) were classified as \u2018adherent\u2019, and 46 subjects (30.87%) were labelled as \u2018partially adherent\u2019 to Clinical Practice Guidelines. Participants\u2019 assessment and therapeutic tools selection was generally aligned with the Clinical Practice Guidelines\u2019 extolled recommendations, except for tender points examination and massage therapy. A number of 14 out of the 24 statements exceeded the predefined 70% agreement threshold.\u00a0The current study reflects an adequate level of knowledge and adherence amongst physiotherapists in Denmark. Further research and targeted implementation strategies are needed to reduce the evidence-to-practice gap.<\/jats:p>","DOI":"10.1007\/s00296-026-06084-6","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T06:12:03Z","timestamp":1771395123000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical practice guidelines in fibromyalgia. Physiotherapists\u2019 adherence in Denmark: a cross-sectional web-based survey study"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-073X","authenticated-orcid":false,"given":"J. 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