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This activity is unrelated to the present study and did not influence the study design, analysis, or interpretation of the results, or preparation of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The present secondary analysis of anonymized OAI data was conducted in accordance with the Declaration of Helsinki (October 2024 version), and the study protocol was approved by the Institutional Review Board of Juntendo University (approval number: 00333; approval date: March 31, 2026).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all OAI participants in the original cohort study. The requirement for additional written informed consent for the present secondary analysis was waived because anonymized data were used.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The author used ChatGPT (OpenAI, GPT-5.4 and GPT-5.5, accessed in May 2026) to assist with language refinement and review of R scripts. All AI-assisted outputs were reviewed, revised, and verified by the author, who takes full responsibility for the content of the manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Use of artificial intelligence tools"}},{"value":"No part of this manuscript has been copied or published elsewhere, in whole or in part.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}],"article-number":"97"}}