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Evidence for yoga as a mind\u2013body intervention remains limited. This study aimed to assess the effects of an 8-week yoga program on mobility, function, disease activity, activity-related competences, and psychological outcomes in axSpA compared with physiotherapy and healthy individuals.\u00a0We conducted a prospective, non-randomized, study (University Hospital Erlangen, May 2021\u2013January 2024). AxSpA patients participated either in weekly yoga sessions for 8\u00a0weeks (approximately 60\u00a0min; online format) or received standard individual physiotherapy (\u2265\u200930\u00a0min\/week). A healthy control group completed the same yoga program. Health related outcomes at baseline and follow-up were measured and changes were analysed using linear mixed-effects models.\u00a0Seventy-six participants were included. In axSpA, spinal mobility improved in the yoga group (BASMI \u0394\u2009\u2212\u20090.31; p\u2009=\u20090.002), while the physiotherapy group worsened (\u0394\u2009+\u20090.29; p\u2009=\u20090.003). Physical activity related health competency (control competence \u0394\u2009+\u20091.10; p\u2009=\u20090.001; self-regulation \u0394\u2009+\u20090.72; p\u2009=\u20090.021) and psychological outcomes improved in the yoga group with increased quality of life mental scores (\u0394\u2009+\u20096.62; p\u2009&lt;\u20090.001) and reduced kinesiophobia (TSK \u0394\u2009\u2212\u20093.25; p\u2009=\u20090.008); physiotherapy showed no meaningful changes. Disease activity showed a significant decrease in the yoga group (BASDAI \u0394 \u20130.44; p\u2009=\u20090.049). Healthy individuals showed similar directional changes with smaller effects.\u00a0An 8-week yoga intervention was associated with improvements in mobility, psychological outcomes and activity-related competences. Findings support yoga as a complementary treatment addressing both physical and psychological dimensions of axSpA.\u00a0The study was registered in the German Clinical Trials Register (DRKS-ID: DRKS00025215).<\/jats:p>","DOI":"10.1007\/s00296-026-06202-4","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T07:49:49Z","timestamp":1782114589000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Yoga on Spinal Mobility and Psychological Outcomes in Patients with Axial Spondyloarthritis: A Prospective Non-randomized Controlled Study"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2665-7308","authenticated-orcid":false,"given":"Vanessa","family":"Bundle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1336-7741","authenticated-orcid":false,"given":"Claudia","family":"Bouzas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0804-3198","authenticated-orcid":false,"given":"Alp","family":"Temiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2750-8726","authenticated-orcid":false,"given":"Birte","family":"Coppers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3438-6089","authenticated-orcid":false,"given":"Ines","family":"Ebner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9828-3890","authenticated-orcid":false,"given":"Paloma Palm","family":"von Alten Blaskowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5040-9643","authenticated-orcid":false,"given":"Sebastian","family":"Rudolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0739-1959","authenticated-orcid":false,"given":"Anna-Maria","family":"Liphardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2020-6711","authenticated-orcid":false,"given":"Maria Gabriella","family":"Raimondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6934-981X","authenticated-orcid":false,"given":"Andreas","family":"Wirsching","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6583-6237","authenticated-orcid":false,"given":"Elizabeth","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6122-0774","authenticated-orcid":false,"given":"Filippo","family":"Fagni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7003-501X","authenticated-orcid":false,"given":"Andreas","family":"Ramming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8740-9615","authenticated-orcid":false,"given":"Georg","family":"Schett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6688-2155","authenticated-orcid":false,"given":"Harriet","family":"Morf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"6202_CR1","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1038\/s41413-019-0057-8","volume":"7","author":"W Zhu","year":"2019","unstructured":"Zhu W, He X, Cheng K, Zhang L, Chen D, Wang X, Qiu G, Cao X, Weng X (2019) Ankylosing spondylitis: etiology, pathogenesis, and treatments. 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