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This cross-sectional analysis of the\n                    <jats:italic>STudying Ageing in Rheumatoid arthritis<\/jats:italic>\n                    (STAR) study included 207 patients with RA and 214 population controls aged 55\u201385 years. Physical function was assessed by the self-reported Health Assessment Questionnaire-Disability Index (HAQ-DI) and Cochin hand function scale, and three performance measures including handgrip strength, gait speed and the five-times sit-to-stand test (FTSST) in a subgroup (RA:\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200988, controls:\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009108). Multivariable regression models assessed associations between age, group (RA\/control), and each measure of physical function, adjusting for sociodemographic and clinical factors. Interactions age*group were tested. No meaningful age*group interactions were observed, except for a small effect on the FTSST. Age correlated weakly with measures of physical function in both groups and was, in multivariable analyses, only modestly associated with worse HAQ-DI (\u03b2\u2009=\u20090.01\/year; 95%CI: 0.01\u20130.02), higher Cochin hand disability (worsening 2%\/year), lower handgrip strength (\u03b2 = -0.4\u00a0kg\/year; 95%CI: -0.6 to -0.2), and a slightly slower gait speed (\u03b2 = -0.01\u00a0m\/s\/year; 95%CI: -0.02 to -0.01). RA was independently associated with worse HAQ-DI (\u03b2\u2009=\u20090.12; 95%CI: 0.04\u20130.21), 40% higher Cochin scores, and lower handgrip strength (\u03b2=-3.2\u00a0kg; 95%CI:-6.1 to -0.4), but not with gait speed or FTSST. Fatigue and pain were the main covariables attenuating the association of age or group with physical function. Although older adults with RA experience worse self-reported physical function and lower grip strength, this was similar compared to population controls and suggests generic processes of ageing.\n                  <\/jats:p>","DOI":"10.1007\/s00296-026-06204-2","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:22:06Z","timestamp":1781670126000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Physical function in older people with rheumatoid arthritis and population controls: a cross-sectional study of self-reported and performance-based measures"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1252-5026","authenticated-orcid":false,"given":"Saskia P. 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AB has received to her department research grants from AbbVie and Celgene and consultancy fees from UCB, Eli Lilly, Novartis, Sandoz and Alfasigma. SR has received research grants and\/or consultancy fees from AbbVie, Alfasigma, Eli Lilly, MSD, Novartis, Pfizer, Takeda, and UCB and is a member of the Executive Committee of the Assessment of Spondyloarthritis international society and of the EULAR Quality of Care Committee. MO has received to her department consultancy fees from Novartis, Pfizer and Alfasigma. Research grant: Pfizer and ReumaNederland. This study was funded by Pfizer and the Dutch Arthritis Society (ReumaNederland), who had no role in the design, conduct, analysis, or reporting of the study.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No part of this report is copied or published elsewhere in whole or in part.","order":2,"name":"Ethics","label":"Disclaimer","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"During the preparation of this work the author(s) used ChatGPT (OpenAI) in order to rephrase sentences and refining spelling and grammar. After using this tool\/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.","order":3,"name":"Ethics","label":"Declaration of generative AI and AI-assisted technologies in the manuscript preparation process","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"155"}}