{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T04:24:31Z","timestamp":1786940671085,"version":"build-2736575974"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005760","name":"University of Gothenburg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005760","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Intraarticular corticosteroid injections (ISA) are frequently used in rheumatoid arthritis (RA). In spite of this there are few studies on ISA in finger joints in RA. We set out to identify patient-experienced effect of ISA in RA patients regarding pain and mobility of injected arthritic joints, predictors thereof, time span to symptom relief and effect duration. RA patients, \u2265\u200918 years, were asked to participate just after having received an ISA, with methylprednisolone (MP), in a metacarpophalangeal (MCP) or proximal interphalangeal (PIP) joint, due to arthritis. Patient characteristics, degree of arthritis, CRP and ESR were collected at inclusion. Pain and mobility in the injected joint were reported by the patient on day of inclusion and the following 14 days. Primary outcome was defined as Numerical Rating Scale (NRS) pain\u2009\u2264\u20092 (NRS-scale 0\u201310) in the injected joint at day 14. Secondary outcomes were NRS mobility, time span and predictors of fulfilling the primary outcome and effect duration. Three-quarters of RA patients responded to ISA regarding pain, most within four days. Mobility improved in two-thirds after 14 days. PIP joints responded better than MCP joints. The only significant predictor was injected MP volume. Among responders, effect persisted for at least three months. ISA is an effective therapy with 75% of RA patients responding over 14 days. PIP joints tend to respond better than MCP joints and the only other predictor for good outcome is volume MP injected, where response increased with volume.<\/jats:p>","DOI":"10.1007\/s00296-026-06257-3","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:51:44Z","timestamp":1784872304000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapid pain response following intra-articular steroid injections in rheumatoid arthritis finger joints: a prospective study with daily patient self-assessment"],"prefix":"10.1007","volume":"46","author":[{"given":"Marie","family":"Kebke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmy","family":"Adolfsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5252-8710","authenticated-orcid":false,"given":"Joakim","family":"Str\u00f6mberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5165-0968","authenticated-orcid":false,"given":"Mats","family":"Dehlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"issue":"9","key":"6257_CR1","first-page":"1691","volume":"32","author":"RN Furtado","year":"2005","unstructured":"Furtado RN, Oliveira LM, Natour J (2005) Polyarticular corticosteroid injection versus systemic administration in treatment of rheumatoid arthritis patients: a randomized controlled study. J Rhuematol 32(9):1691\u20131698","journal-title":"J Rhuematol"},{"issue":"1","key":"6257_CR2","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1136\/ard.56.1.71","volume":"56","author":"PS Helliwell","year":"1997","unstructured":"Helliwell PS (1997) Use of an objective measure of articular stiffness to record changes in finger joints after intra-articular injection of corticosteroid. Ann Rheum Dis 56(1):71\u201373. https:\/\/doi.org\/10.1136\/ard.56.1.71","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"6257_CR3","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3109\/03009748309101996","volume":"12","author":"S Jalava","year":"1983","unstructured":"Jalava S, Saario R (1983) Treatment of Finger Joints with Local Steroids: A Double-blind Study. Scand J Rheumatol 12(1):12\u201314. https:\/\/doi.org\/10.3109\/03009748309101996","journal-title":"Scand J Rheumatol"},{"issue":"7","key":"6257_CR4","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1016\/j.pmrj.2018.09.040","volume":"11","author":"DM Cushman","year":"2019","unstructured":"Cushman DM, Ofek E, Syed RH, Clements N, Gardner JE, Sams JM et al (2019) Comparison of varying corticosteroid type, dose, and volume for the treatment of pain in small-and intermediate\u2010size joint injections: a narrative review. PM&R 11(7):758\u2013770. https:\/\/doi.org\/10.1016\/j.pmrj.2018.09.040","journal-title":"PM&R"},{"issue":"6","key":"6257_CR5","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.3904\/kjim.2020.189","volume":"36","author":"JH Koh","year":"2021","unstructured":"Koh JH, Lee H, Lee S-G (2021) Predictors of joint damage in patients with rheumatoid arthritis: focus on short-and long-term effects of intra-articular glucocorticoid injections. 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Medicine 98(33):e16714","journal-title":"Medicine"},{"key":"6257_CR8","doi-asserted-by":"publisher","unstructured":"Hetland ML, \u00d8stergaard M, Ejbjerg B, Jacobsen S, Stengaard-Pedersen K, Junker P et al (2012) Short-and long-term efficacy of intra-articular injections with betamethasone as part of a treat-to-target strategy in early rheumatoid arthritis: impact of joint area, repeated injections, MRI findings, anti-CCP, IgM-RF and CRP. Annals of the rheumatic diseases. 71(6):851\u2013856. https:\/\/doi.org\/10.1136\/annrheumdis-2011-200632","DOI":"10.1136\/annrheumdis-2011-200632"},{"issue":"5","key":"6257_CR9","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1007\/s00296-021-05045-5","volume":"42","author":"J de la Torre-Aboki","year":"2022","unstructured":"de la Torre-Aboki J, Uson J, Pitsillidou I, Vardanyan V, Nikiphorou E, Rodriguez-Garcia SC et al (2022) Intra-articular therapies: patient preferences and professional practices in European countries. Rheumatol Int 42(5):869\u2013878. https:\/\/doi.org\/10.1007\/s00296-021-05045-5","journal-title":"Rheumatol Int"},{"key":"6257_CR10","unstructured":"AM D-M, JEF (2023) Safety of intra-articular glucocorticoid injections-state of the art. 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No AI was used for drafting or editing this report.","order":2,"name":"Ethics","label":"AI","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"223"}}