{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:55:26Z","timestamp":1790934926776,"version":"4.1.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472008"],"award-info":[{"award-number":["82472008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Health and Family Planning Commission Fund","award":["202240235"],"award-info":[{"award-number":["202240235"]}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["21ZR1451400"],"award-info":[{"award-number":["21ZR1451400"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Int"],"DOI":"10.1007\/s00296-026-06274-2","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:01:16Z","timestamp":1786982476000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between disease activity, arterial stiffness, and 10-year cardiovascular risk in patients with rheumatoid arthritis: a cross-sectional study"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3873-0178","authenticated-orcid":false,"given":"Senning","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6523-5828","authenticated-orcid":false,"given":"Ming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5555-3290","authenticated-orcid":false,"given":"Mengjiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1989-5766","authenticated-orcid":false,"given":"Zhenyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4829-4034","authenticated-orcid":false,"given":"Hanwen","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3409-2073","authenticated-orcid":false,"given":"Hairong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3924-0024","authenticated-orcid":false,"given":"Panpan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2915-1942","authenticated-orcid":false,"given":"Wenling","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7743-4296","authenticated-orcid":false,"given":"Rong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7797-8945","authenticated-orcid":false,"given":"Tianyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-4836","authenticated-orcid":false,"given":"Lin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6459-3667","authenticated-orcid":false,"given":"Zhaojun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"issue":"1","key":"6274_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2025.102036","volume":"39","author":"P Uke","year":"2025","unstructured":"Uke P, Maharaj A, Adebajo A (2025) A review on the epidemiology of rheumatoid arthritis: an update and trends from current literature. Best Pract Res Clin Rheumatol 39(1):102036. https:\/\/doi.org\/10.1016\/j.berh.2025.102036","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"6274_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14186409","author":"S Fujimoto","year":"2025","unstructured":"Fujimoto S, Niiro H (2025) Pathogenic role of cytokines in rheumatoid arthritis. J Clin Med. https:\/\/doi.org\/10.3390\/jcm14186409","journal-title":"J Clin Med"},{"issue":"7","key":"6274_CR3","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/s41584-023-00969-7","volume":"19","author":"BN Weber","year":"2023","unstructured":"Weber BN, Giles JT, Liao KP (2023) Shared inflammatory pathways of rheumatoid arthritis and atherosclerotic cardiovascular disease. Nat Rev Rheumatol 19(7):417\u2013428. https:\/\/doi.org\/10.1038\/s41584-023-00969-7","journal-title":"Nat Rev Rheumatol"},{"key":"6274_CR4","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.cytogfr.2025.01.002","volume":"83","author":"A Saran","year":"2025","unstructured":"Saran A, Nishizaki D, Lippman SM, Kato S, Kurzrock R (2025) Interleukin-17: a pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders. Cytokine Growth Factor Rev 83:35\u201344. https:\/\/doi.org\/10.1016\/j.cytogfr.2025.01.002","journal-title":"Cytokine Growth Factor Rev"},{"issue":"22","key":"6274_CR5","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.030211","volume":"12","author":"Y Guo","year":"2023","unstructured":"Guo Y, Chung W, Shan Z, Zhu Z, Costenbader KH, Liang L (2023) Genome-wide assessment of shared genetic architecture between rheumatoid arthritis and cardiovascular diseases. J Am Heart Assoc 12(22):e030211. https:\/\/doi.org\/10.1161\/JAHA.123.030211","journal-title":"J Am Heart Assoc"},{"issue":"9","key":"6274_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2021.102891","volume":"20","author":"M Berger","year":"2021","unstructured":"Berger M, Fesler P, Roubille C (2021) Arterial stiffness, the hidden face of cardiovascular risk in autoimmune and chronic inflammatory rheumatic diseases. Autoimmun Rev 20(9):102891. https:\/\/doi.org\/10.1016\/j.autrev.2021.102891","journal-title":"Autoimmun Rev"},{"issue":"13","key":"6274_CR7","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.jacc.2009.10.061","volume":"55","author":"C Vlachopoulos","year":"2010","unstructured":"Vlachopoulos C, Aznaouridis K, Stefanadis C (2010) Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 55(13):1318\u20131327. https:\/\/doi.org\/10.1016\/j.jacc.2009.10.061","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"6274_CR8","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1093\/ajh\/hpaf113","volume":"38","author":"L Yang","year":"2025","unstructured":"Yang L, Li X, Li Z, Xi G, Wang X, Chen A et al (2025) Ventricular-arterial coupling derived from arterial velocity pulse index to global longitudinal strain ratio in hypertension. Am J Hypertens 38(11):947\u2013956. https:\/\/doi.org\/10.1093\/ajh\/hpaf113","journal-title":"Am J Hypertens"},{"issue":"4","key":"6274_CR9","doi-asserted-by":"publisher","first-page":"348","DOI":"10.37015\/AUDT.2023.230045","volume":"7","author":"XL Lin Jin","year":"2023","unstructured":"Lin Jin XL, Zhang M, Zhang X, Liang CXF, Li Z (2023) Arterial stiffness and cardiovascular risk: the role of brachial cuff-measured index. Adv Ultrasound Diag Therapy 7(4):348\u2013355","journal-title":"Adv Ultrasound Diag Therapy"},{"key":"6274_CR10","doi-asserted-by":"publisher","first-page":"100096","DOI":"10.1016\/j.lanwpc.2021.100096","volume":"8","author":"J Li","year":"2021","unstructured":"Li J, Liu F, Yang X, Cao J, Chen S, Chen J et al (2021) Validating world health organization cardiovascular disease risk charts and optimizing risk assessment in China. Lancet Reg Health West Pac 8:100096. https:\/\/doi.org\/10.1016\/j.lanwpc.2021.100096","journal-title":"Lancet Reg Health West Pac"},{"issue":"19","key":"6274_CR11","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1161\/circulationaha.116.022367","volume":"134","author":"X Yang","year":"2016","unstructured":"Yang X, Li J, Hu D, Chen J, Li Y, Huang J et al (2016) Predicting the 10-year risks of atherosclerotic cardiovascular disease in chinese population: the China-PAR project (Prediction for ASCVD Risk in China). Circulation 134(19):1430\u20131440. https:\/\/doi.org\/10.1161\/circulationaha.116.022367","journal-title":"Circulation"},{"key":"6274_CR12","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.138461","author":"D Aletaha","year":"2010","unstructured":"Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO III et al (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European league against Rheumatism collaborative initiative. Ann Rheum Dis. https:\/\/doi.org\/10.1136\/ard.2010.138461","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"6274_CR13","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1002\/art.1780380107","volume":"38","author":"ML Prevoo","year":"1995","unstructured":"Prevoo ML, van \u2019t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38(1):44\u20138. https:\/\/doi.org\/10.1002\/art.1780380107","journal-title":"Arthritis Rheum"},{"key":"6274_CR14","unstructured":"The development of the disease activity score (DAS) and the disease activity score using 28 joint counts (DAS28)"},{"key":"6274_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.862849","volume":"13","author":"X Zhang","year":"2022","unstructured":"Zhang X, Qiao P, Guo Q, Liang Z, Pan J, Wu F et al (2022) High follicle-stimulating hormone level associated with risk of rheumatoid arthritis and disease activity. Front Endocrinol (Lausanne) 13:862849. https:\/\/doi.org\/10.3389\/fendo.2022.862849","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"6274_CR16","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.rdc.2009.10.001","volume":"35","author":"J Fransen","year":"2009","unstructured":"Fransen J, van Riel PL (2009) The disease activity score and the EULAR response criteria. Rheum Dis Clin North Am 35(4):745\u201357vii. https:\/\/doi.org\/10.1016\/j.rdc.2009.10.001","journal-title":"Rheum Dis Clin North Am"},{"issue":"5","key":"6274_CR17","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1080\/10641963.2019.1705319","volume":"42","author":"J Wan","year":"2020","unstructured":"Wan J, Liu S, Yang Y, Wang D, Ran F, Xia S et al (2020) Roles of arterial pressure volume index and arterial velocity pulse index trajectories in risk prediction in hypertensive patients with heart failure with preserved ejection fraction. Clin Exp Hypertens 42(5):469\u2013478. https:\/\/doi.org\/10.1080\/10641963.2019.1705319","journal-title":"Clin Exp Hypertens"},{"key":"6274_CR18","doi-asserted-by":"publisher","first-page":"1460826","DOI":"10.3389\/fcvm.2024.1460826","volume":"11","author":"J Chen","year":"2024","unstructured":"Chen J, Yang X, Li X, Jin L, Wu L, Zhang M et al (2024) Association between myocardial layer-specific strain and high 10-year risk of atherosclerotic cardiovascular disease in hypertension-findings from the China-PAR project study. Front Cardiovasc Med 11:1460826. https:\/\/doi.org\/10.3389\/fcvm.2024.1460826","journal-title":"Front Cardiovasc Med"},{"issue":"10 Suppl 1","key":"6274_CR19","doi-asserted-by":"publisher","first-page":"S21","DOI":"10.1016\/j.amjmed.2008.06.014","volume":"121","author":"P Libby","year":"2008","unstructured":"Libby P (2008) Role of inflammation in atherosclerosis associated with rheumatoid arthritis. Am J Med 121(10 Suppl 1):S21-31. https:\/\/doi.org\/10.1016\/j.amjmed.2008.06.014","journal-title":"Am J Med"},{"key":"6274_CR20","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59091550","author":"D Bedekovic","year":"2023","unstructured":"Bedekovic D, Bosnjak I, Saric S, Kirner D, Novak S (2023) Role of inflammatory cytokines in rheumatoid arthritis and development of atherosclerosis: a review. Med (Kaunas). https:\/\/doi.org\/10.3390\/medicina59091550","journal-title":"Med (Kaunas)"},{"key":"6274_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21249505","author":"T Behl","year":"2020","unstructured":"Behl T, Kaur I, Sehgal A, Zengin G, Brisc C, Brisc MC et al (2020) The lipid paradox as a metabolic checkpoint and its therapeutic significance in ameliorating the associated cardiovascular risks in rheumatoid arthritis patients. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms21249505","journal-title":"Int J Mol Sci"},{"issue":"9","key":"6274_CR22","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/nrrheum.2013.91","volume":"9","author":"J Robertson","year":"2013","unstructured":"Robertson J, Peters MJ, McInnes IB, Sattar N (2013) Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nat Rev Rheumatol 9(9):513\u201323. https:\/\/doi.org\/10.1038\/nrrheum.2013.91","journal-title":"Nat Rev Rheumatol"},{"key":"6274_CR23","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26178514","author":"C Xu","year":"2025","unstructured":"Xu C, Rodriguez-Carrio J, Xie Y, Hu F, Chong WM, Hou HW et al (2025) Post-translational modifications of lipoproteins: emerging players linking inflammation and cardiovascular disease in rheumatoid arthritis-a narrative review. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms26178514","journal-title":"Int J Mol Sci"},{"key":"6274_CR24","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20092154","author":"V Mercurio","year":"2019","unstructured":"Mercurio V, Lobasso A, Barbieri L, Parrella P, Ciervo D, Liccardo B et al (2019) Inflammatory, serological and vascular determinants of cardiovascular disease in systemic lupus erythematosus patients. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms20092154","journal-title":"Int J Mol Sci"},{"issue":"33","key":"6274_CR25","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007862","volume":"96","author":"M Vazquez-Del Mercado","year":"2017","unstructured":"Vazquez-Del Mercado M, Gomez-Banuelos E, Chavarria-Avila E, Cardona-Munoz E, Ramos-Becerra C, Alanis-Sanchez A et al (2017) Disease duration of rheumatoid arthritis is a predictor of vascular stiffness: a cross-sectional study in patients without known cardiovascular comorbidities: a STROBE-compliant article. Medicine (Baltimore) 96(33):e7862. https:\/\/doi.org\/10.1097\/MD.0000000000007862","journal-title":"Medicine (Baltimore)"},{"issue":"8","key":"6274_CR26","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.3899\/jrheum.170029","volume":"44","author":"S Gunter","year":"2017","unstructured":"Gunter S, Robinson C, Norton GR, Woodiwiss AJ, Tsang L, Dessein PH, Millen AME (2017) Cardiovascular risk factors and disease characteristics are consistently associated with arterial function in rheumatoid arthritis. J Rheumatol 44(8):1125\u20131133. https:\/\/doi.org\/10.3899\/jrheum.170029","journal-title":"J Rheumatol"}],"container-title":["Rheumatology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-026-06274-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00296-026-06274-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00296-026-06274-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:09:56Z","timestamp":1790932196000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00296-026-06274-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":26,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["6274"],"URL":"https:\/\/doi.org\/10.1007\/s00296-026-06274-2","relation":{},"ISSN":["1437-160X"],"issn-type":[{"value":"1437-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]},"assertion":[{"value":"18 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee of Guanghua Hospital Affiliated with Shanghai University of Traditional Chinese Medicine (date: August 14, 2023: number: 2023-K-46). The study was conducted in accordance with the 2024 Declaration of Helsinki and the Ethical Guidelines for Medical and Health Research Involving Human Subjects in China. The requirement for written informed consent was waived, given the retrospective design of the study.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"237"}}