{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:37:56Z","timestamp":1792802276963,"version":"4.5.0"},"reference-count":136,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:00:00Z","timestamp":1792800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:00:00Z","timestamp":1792800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Plant Cell Rep"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1007\/s00299-026-04028-9","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:06:23Z","timestamp":1792796783000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Heavy metal stress mitigation in plants by metal-resistant fungi: molecular and biotechnological insights"],"prefix":"10.1007","volume":"45","author":[{"given":"Sparsh","family":"Choudhary","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7012-1815","authenticated-orcid":false,"given":"Kanwarpreet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankush","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheifali","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Juneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,24]]},"reference":[{"issue":"1","key":"4028_CR1","doi-asserted-by":"publisher","first-page":"038","DOI":"10.17352\/ojeb.000007","volume":"2","author":"E Abatenh","year":"2017","unstructured":"Abatenh E, Gizaw B, Tsegaye Z, Wassie M (2017) The role of microorganisms in bioremediation-A review. Open J Environ Biol 2(1):038\u2013046","journal-title":"Open J Environ Biol"},{"key":"4028_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2020.110501","volume":"297","author":"P Agarwal","year":"2020","unstructured":"Agarwal P, Mitra M, Banerjee S, Roy S (2020) MYB4 transcription factor, a member of R2R3-subfamily of MYB domain protein, regulates cadmium tolerance via enhanced protection against oxidative damage and increases expression of PCS1 and MT1C in Arabidopsis. Plant Sci 297:110501","journal-title":"Plant Sci"},{"key":"4028_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/s00374-025-01973-7","author":"N Ahmed","year":"2026","unstructured":"Ahmed N, Wang C, Li J, Deng L, Zhang Y, Chachar S, Tu P (2026) The multifunctional roles of arbuscular mycorrhizal fungi in soil health and nutrient dynamics. Biol Fertility Soils. https:\/\/doi.org\/10.1007\/s00374-025-01973-7","journal-title":"Biol Fertility Soils"},{"issue":"1","key":"4028_CR4","first-page":"6730305","volume":"2019","author":"H Ali","year":"2019","unstructured":"Ali H, Khan E, Ilahi I (2019) Environmental chemistry and ecotoxicology of hazardous heavy metals: environmental persistence, toxicity, and bioaccumulation. J Chem 2019(1):6730305","journal-title":"J Chem"},{"issue":"2","key":"4028_CR5","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1016\/j.biortech.2010.08.087","volume":"102","author":"F Amiri","year":"2011","unstructured":"Amiri F, Yaghmaei S, Mousavi SM (2011) Bioleaching of tungsten-rich spent hydrocracking catalyst using Penicillium simplicissimum. Bioresour Technol 102(2):1567\u20131573","journal-title":"Bioresour Technol"},{"issue":"2","key":"4028_CR6","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/S1002-0160(17)60311-4","volume":"27","author":"ALI Amjad","year":"2017","unstructured":"Amjad ALI, Di GUO, Ping WANG, Feng SHEN, Ronghua LI (2017) Mycoremediation of potentially toxic trace elements\u2014a biological tool for soil cleanup: a review. Pedosphere 27(2):205\u2013222","journal-title":"Pedosphere"},{"issue":"8","key":"4028_CR7","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1016\/j.chemosphere.2005.07.044","volume":"62","author":"YJ An","year":"2006","unstructured":"An YJ (2006) Assessment of comparative toxicities of lead and copper using plant assay. Chemosphere 62(8):1359\u20131365","journal-title":"Chemosphere"},{"issue":"3","key":"4028_CR8","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/j.scient.2011.05.015","volume":"18","author":"S Anahid","year":"2011","unstructured":"Anahid S, Yaghmaei S, Ghobadinejad Z (2011) Heavy metal tolerance of fungi. Sci Iran 18(3):502\u2013508","journal-title":"Sci Iran"},{"issue":"1","key":"4028_CR9","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S0141-0229(02)00245-4","volume":"32","author":"P Baldrian","year":"2003","unstructured":"Baldrian P (2003) Interactions of heavy metals with white-rot fungi. Enzyme Microb Technol 32(1):78\u201391","journal-title":"Enzyme Microb Technol"},{"issue":"4","key":"4028_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26041464","volume":"26","author":"X Bao","year":"2025","unstructured":"Bao X, Liu J, Qiu G, Chen X, Zhang J, Wang H, Zhang Q, Guo B (2025) The effect of Rhizophagus intraradices on cadmium uptake and OsNRAMP5 gene expression in rice. Int J Mol Sci 26(4):1464. https:\/\/doi.org\/10.3390\/ijms26041464","journal-title":"Int J Mol Sci"},{"issue":"8","key":"4028_CR11","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1093\/jxb\/eraf042","volume":"76","author":"B Benbrik","year":"2025","unstructured":"Benbrik B, Reid TE, Nkir D, Chaouki H, Aallam Y, Clark IM, Mauchline TH, Harris J, Pawlett M, Barakat A, Rchiad Z, Bargaz A (2025) Unlocking the agro-physiological potential of wheat rhizoplane fungi under low P conditions using a niche-conserved consortium approach. J Exp Bot 76(8):2320\u20132337","journal-title":"J Exp Bot"},{"issue":"1","key":"4028_CR12","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1475-2859-13-66","volume":"13","author":"D Bhardwaj","year":"2014","unstructured":"Bhardwaj D, Ansari MW, Sahoo RK, Tuteja N (2014) Biofertilizers function as key player in sustainable agriculture by improving soil fertility, plant tolerance and crop productivity. Microb Cell Fact 13(1):66","journal-title":"Microb Cell Fact"},{"issue":"12","key":"4028_CR13","doi-asserted-by":"publisher","first-page":"6802","DOI":"10.1007\/s00344-024-11467-9","volume":"44","author":"I Bhupenchandra","year":"2025","unstructured":"Bhupenchandra I, Chongtham SK, Devi AG, Dutta P, Sahoo MR, Mohanty S, Kumar S, Choudhary AK, Devi EL, Sinyorita S, Devi SH, Mahanta M, Kumari A, Devi HL, Josmee RK, Pusparani A, Pathaw N, Gupta S, Meena M, Janmeda P, Seth CS, Arora J, Sahoo A, Swapnil P (2025) Unlocking the potential of arbuscular mycorrhizal fungi: exploring role in plant growth promotion, nutrient uptake mechanisms, biotic stress alleviation, and sustaining agricultural production systems. J Plant Growth Regul 44(12):6802\u20136840","journal-title":"J Plant Growth Regul"},{"issue":"1-2","key":"4028_CR14","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1163\/22238980-00001025","volume":"65","author":"N Bhutani","year":"2018","unstructured":"Bhutani N, Maheshwari R, Negi M, Suneja P (2018) Optimization of IAA production by endophytic Bacillus spp. from Vigna radiata for their potential use as plant growth promoters. Isr J Plant Sci 65(1\u20132):83\u201396","journal-title":"Isr J Plant Sci"},{"issue":"2","key":"4028_CR15","first-page":"835","volume":"12","author":"M Bibi","year":"2023","unstructured":"Bibi M, Samiullah FB, Saba Afzal S (2023) Essential and non-essential heavy metals sources and impacts on human health and plants. Pure Appl Biol (PAB) 12(2):835\u2013847","journal-title":"Pure Appl Biol (PAB)"},{"key":"4028_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2019.111931","volume":"143","author":"S Bilal","year":"2020","unstructured":"Bilal S, Shahzad R, Imran M, Jan R, Kim KM, Lee IJ (2020) Synergistic association of endophytic fungi enhances Glycine max L. resilience to combined abiotic stresses: heavy metals, high temperature and drought stress. Ind Crops Prod 143:111931","journal-title":"Ind Crops Prod"},{"issue":"1","key":"4028_CR17","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s12035-026-05672-8","volume":"63","author":"G Bj\u00f8rklund","year":"2026","unstructured":"Bj\u00f8rklund G, Butnariu M, Caunii A, Peana M (2026) Metallothioneins in neurodegenerative diseases: metal homeostasis, autoimmunity, and therapeutic potential. Mol Neurobiol 63(1):373","journal-title":"Mol Neurobiol"},{"key":"4028_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.wen.2025.12.005","author":"D Bose","year":"2025","unstructured":"Bose D, Bhattacharya R, Pillai M, Ray A, Kaur T, Mondal S, Mondal A (2025) State-of-the-art review on sediment microbial fuel cells: evolution, innovations, challenges, scalability, and policy implications for sustainable development. Water-Energy Nexus. https:\/\/doi.org\/10.1016\/j.wen.2025.12.005","journal-title":"Water-Energy Nexus"},{"key":"4028_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2025.110470","volume":"229","author":"G Boyno","year":"2025","unstructured":"Boyno G (2025) Biological defence against cadmium stress in wheat with arbuscular mycorrhizal fungi and Trichoderma: synergistic effects on plant and soil health. Plant Physiol Biochem 229:110470","journal-title":"Plant Physiol Biochem"},{"issue":"6","key":"4028_CR20","doi-asserted-by":"publisher","first-page":"2158","DOI":"10.1111\/nph.18308","volume":"235","author":"S Branco","year":"2022","unstructured":"Branco S, Schauster A, Liao HL, Ruytinx J (2022) Mechanisms of stress tolerance and their effects on the ecology and evolution of mycorrhizal fungi. New Phytol 235(6):2158\u20132175","journal-title":"New Phytol"},{"key":"4028_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e04691","author":"J Briffa","year":"2020","unstructured":"Briffa J, Sinagra E, Blundell R (2020) Heavy metal pollution in the environment and their toxicological effects on humans. Heliyon. https:\/\/doi.org\/10.1016\/j.heliyon.2020.e04691","journal-title":"Heliyon"},{"key":"4028_CR22","doi-asserted-by":"publisher","DOI":"10.1101\/2020.07.13.201566","author":"J Chauhan","year":"2020","unstructured":"Chauhan J, Saini I, Kaushik P (2020) Studies on the biosorption potential of copper by Rhizopus arrhizus biomass. BioRxiv. https:\/\/doi.org\/10.1101\/2020.07.13.201566","journal-title":"BioRxiv"},{"issue":"1","key":"4028_CR23","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/s12866-024-03252-1","volume":"24","author":"D Chen","year":"2024","unstructured":"Chen D, Wang Y, Li N, Huang Y, Mao Y, Liu X, Du YaRong, Sun K (2024) Transcriptomic and physiological analyses of Trichoderma citrinoviride HT-1 assisted phytoremediation of Cd contaminated water by Phragmites australis. BMC Microbiol 24(1):93","journal-title":"BMC Microbiol"},{"issue":"8","key":"4028_CR24","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1039\/c2mt20041d","volume":"4","author":"S Cherrad","year":"2012","unstructured":"Cherrad S, Girard V, Dieryckx C, Goncalves IR, Dupuy JW, Bonneu M, Rascle C, Job C, Job D, Vacher S, Poussereau N (2012) Proteomic analysis of proteins secreted by Botrytis cinerea in response to heavy metal toxicity. Metallomics 4(8):835\u2013846","journal-title":"Metallomics"},{"key":"4028_CR25","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/978-3-031-56642-4_3","volume-title":"Heavy metal toxicity: human health impact and mitigation strategies","author":"FN Chowdhury","year":"2024","unstructured":"Chowdhury FN, Rahman MM (2024) Source and distribution of heavy metal and their effects on human health. Heavy metal toxicity: human health impact and mitigation strategies. Springer Nature Switzerland, Cham, pp 45\u201398"},{"issue":"6","key":"4028_CR26","doi-asserted-by":"publisher","first-page":"621","DOI":"10.3390\/agronomy16060621","volume":"16","author":"MA Cucu","year":"2026","unstructured":"Cucu MA, Valeria T, Carnevali P, Ghizzoni R, Caterina M (2026) Cereal health regulation by arbuscular mycorrhizal fungi (AMF): insights from tripartite plant\u2013AMF\u2013pathogen systems within the one health framework. Agronomy 16(6):621","journal-title":"Agronomy"},{"key":"4028_CR27","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jhazmat.2012.06.054","volume":"233","author":"X Deng","year":"2012","unstructured":"Deng X, Chai L, Yang Z, Tang C, Tong H, Yuan P (2012) Bioleaching of heavy metals from a contaminated soil using indigenous Penicillium chrysogenum strain F1. J Hazard Mater 233:25\u201332","journal-title":"J Hazard Mater"},{"key":"4028_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.872576","volume":"13","author":"P Dey","year":"2022","unstructured":"Dey P, Malik A, Singh DK, Haange SB, von Bergen M, Jehmlich N (2022) Insight into the molecular mechanisms underpinning the mycoremediation of multiple metals by proteomic technique. Front Microbiol 13:872576","journal-title":"Front Microbiol"},{"issue":"10","key":"4028_CR29","doi-asserted-by":"publisher","first-page":"370","DOI":"10.3390\/d12100370","volume":"12","author":"N Diagne","year":"2020","unstructured":"Diagne N, Ngom M, Djighaly PI, Fall D, Hocher V, Svistoonoff S (2020) Roles of arbuscular mycorrhizal fungi on plant growth and performance: importance in biotic and abiotic stressed regulation. Diversity 12(10):370","journal-title":"Diversity"},{"issue":"1","key":"4028_CR30","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1046\/j.1472-765x.2002.01040.x","volume":"34","author":"MA Dias","year":"2002","unstructured":"Dias MA, Lacerda ICA, Pimentel PF, De Castro HF, Rosa CA (2002) Removal of heavy metals by an Aspergillus terreus strain immobilized in a polyurethane matrix. Lett Appl Microbiol 34(1):46\u201350","journal-title":"Lett Appl Microbiol"},{"issue":"1","key":"4028_CR31","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.enceco.2024.07.002","volume":"6","author":"Y Dinakarkumar","year":"2024","unstructured":"Dinakarkumar Y, Ramakrishnan G, Gujjula KR, Vasu V, Balamurugan P, Murali G (2024) Fungal bioremediation: an overview of the mechanisms, applications and future perspectives. Environ Chem Ecotoxicol 6(1):293\u2013302","journal-title":"Environ Chem Ecotoxicol"},{"key":"4028_CR32","doi-asserted-by":"publisher","DOI":"10.3389\/fenvs.2022.920957","volume":"10","author":"C Ding","year":"2022","unstructured":"Ding C, Chen J, Zhu F, Chai L, Lin Z, Zhang K, Shi Y (2022) Biological toxicity of heavy metal (loid) s in natural environments: from microbes to humans. Front Environ Sci 10:920957","journal-title":"Front Environ Sci"},{"key":"4028_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.136206","volume":"480","author":"H Ding","year":"2024","unstructured":"Ding H, Liu J, Liu Q, Guo L, Hang Q, Zhang Y, Jia J, Tao T, Ding C (2024) Risk assessment and source tracing of heavy metals in major rice-producing provinces of Yangtze River Basin. J Hazard Mater 480:136206","journal-title":"J Hazard Mater"},{"key":"4028_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2023.103800","volume":"53","author":"SK Dwivedi","year":"2023","unstructured":"Dwivedi SK (2023) Fungi mediated detoxification of heavy metals: insights on mechanisms, influencing factors and recent developments. J Water Process Eng 53:103800","journal-title":"J Water Process Eng"},{"key":"4028_CR35","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.1044896","volume":"13","author":"NA Elhamouly","year":"2022","unstructured":"Elhamouly NA, Hewedy OA, Zaitoon A, Miraples A, Elshorbagy OT, Hussien S, Peng D (2022) The hidden power of secondary metabolites in plant-fungi interactions and sustainable phytoremediation. Front Plant Sci 13:1044896","journal-title":"Front Plant Sci"},{"key":"4028_CR36","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1178258","volume":"14","author":"MC Enebe","year":"2023","unstructured":"Enebe MC, Erasmus M (2023) Susceptibility and plant immune control\u2014a case of mycorrhizal strategy for plant colonization, symbiosis, and plant immune suppression. Front Microbiol 14:1178258","journal-title":"Front Microbiol"},{"issue":"7","key":"4028_CR37","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.3390\/agriculture13071279","volume":"13","author":"S Fahde","year":"2023","unstructured":"Fahde S, Boughribil S, Sijilmassi B, Amri A (2023) Rhizobia: a promising source of plant growth-promoting molecules and their non-legume interactions: examining applications and mechanisms. Agriculture 13(7):1279","journal-title":"Agriculture"},{"issue":"4","key":"4028_CR38","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1111\/j.1469-8137.2009.03132.x","volume":"185","author":"S Farinati","year":"2010","unstructured":"Farinati S, DalCorso G, Varotto S, Furini A (2010) The Brassica juncea BjCdR15, an ortholog of Arabidopsis TGA3, is a regulator of cadmium uptake, transport and accumulation in shoots and confers cadmium tolerance in transgenic plants. New Phytol 185(4):964\u2013978","journal-title":"New Phytol"},{"issue":"3","key":"4028_CR39","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1111\/j.1758-2229.2011.00283.x","volume":"4","author":"GM Gadd","year":"2012","unstructured":"Gadd GM, Rhee YJ, Stephenson K, Wei Z (2012) Geomycology: metals, actinides and biominerals. Environ Microbiol Rep 4(3):270\u2013296","journal-title":"Environ Microbiol Rep"},{"issue":"5","key":"4028_CR40","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3390\/jox15050146","volume":"15","author":"A Generalova","year":"2025","unstructured":"Generalova A, Davidova S, Satchanska G (2025) The mechanisms of lead toxicity in living organisms. J Xenobiot 15(5):146","journal-title":"J Xenobiot"},{"issue":"3","key":"4028_CR41","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1007\/s13762-019-02215-8","volume":"16","author":"NH Ghori","year":"2019","unstructured":"Ghori NH, Ghori T, Hayat MQ, Imadi SR, Gul A, Altay VOLKAN, Ozturk M (2019) Heavy metal stress and responses in plants. Int J Environ Sci Technol 16(3):1807\u20131828","journal-title":"Int J Environ Sci Technol"},{"issue":"11","key":"4028_CR42","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00299-024-03343-3","volume":"43","author":"K Gogoi","year":"2024","unstructured":"Gogoi K, Gogoi H, Borgohain M, Saikia R, Chikkaputtaiah C, Hiremath S, Basu U (2024) The molecular dynamics between reactive oxygen species (ROS), reactive nitrogen species (RNS) and phytohormones in plant\u2019s response to biotic stress. Plant Cell Rep 43(11):263","journal-title":"Plant Cell Rep"},{"key":"4028_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.122990","volume":"341","author":"T G\u00f3mez-Gallego","year":"2024","unstructured":"G\u00f3mez-Gallego T, Molina-Luz\u00f3n MJ, Con\u00e9j\u00e9ro G, Berthomieu P, Ferrol N (2024) The arbuscular mycorrhizal fungus Rhizophagus irregularis uses the copper exporting ATPase RiCRD1 as a major strategy for copper detoxification. Environ Pollut 341:122990","journal-title":"Environ Pollut"},{"key":"4028_CR44","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1007\/978-981-97-8804-0_16","volume-title":"Fungal endophytes volume II: applications in agroecosystems and plant protection","author":"A Hameed","year":"2025","unstructured":"Hameed A, Qazi M, Rafiq MU, Akhtar H (2025) Fungal endophytes and soilborne fungi. Fungal endophytes volume II: applications in agroecosystems and plant protection. Springer Nature Singapore, Singapore, pp 485\u2013508"},{"key":"4028_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.01492","volume":"8","author":"MK Hasan","year":"2017","unstructured":"Hasan MK, Cheng Y, Kanwar MK, Chu XY, Ahammed GJ, Qi ZY (2017) Responses of plant proteins to heavy metal stress\u2014a review. Front Plant Sci 8:1492","journal-title":"Front Plant Sci"},{"issue":"1","key":"4028_CR46","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-025-06870-7","volume":"25","author":"HM Hassan","year":"2025","unstructured":"Hassan HM, Bakhoum NS, Dawood MG, Sadak MS, Khattab HI (2025) Role of esculin antioxidant on remediation of lead toxicity on flax growth and yield components. BMC Plant Biol 25(1):863","journal-title":"BMC Plant Biol"},{"issue":"3","key":"4028_CR47","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.70974","volume":"178","author":"Y He","year":"2026","unstructured":"He Y, Qiu K, Zhang W, Duan X, Zhao S, Qiu Z, Zhu M (2026) A plant growth-promoting fungus Cladosporium sphaerospermum attenuates cadmium stress in wheat via gene expression and metabolite production. Physiol Plant 178(3):e70974","journal-title":"Physiol Plant"},{"key":"4028_CR48","first-page":"33","volume-title":"Contemporary environmental issues and challenges in era of climate change","author":"S Hembrom","year":"2019","unstructured":"Hembrom S, Singh B, Gupta SK, Nema AK (2019) A comprehensive evaluation of heavy metal contamination in foodstuff and associated human health risk: a global perspective. Contemporary environmental issues and challenges in era of climate change. Springer Singapore, Singapore, pp 33\u201363"},{"issue":"7","key":"4028_CR49","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.1007\/s13369-015-1702-1","volume":"40","author":"S Iram","year":"2015","unstructured":"Iram S, Shabbir R, Zafar H, Javaid M (2015) Biosorption and bioaccumulation of copper and lead by heavy metal-resistant fungal isolates. Arab J Sci Eng 40(7):1867\u20131873","journal-title":"Arab J Sci Eng"},{"issue":"3","key":"4028_CR50","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1023\/A:1023838707715","volume":"50","author":"VB Ivanov","year":"2003","unstructured":"Ivanov VB, Bystrova EI, Seregin IV (2003) Comparative impacts of heavy metals on root growth as related to their specificity and selectivity. Russ J Plant Physiol 50(3):398\u2013406","journal-title":"Russ J Plant Physiol"},{"key":"4028_CR51","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.01617","volume":"8","author":"R Jacoby","year":"2017","unstructured":"Jacoby R, Peukert M, Succurro A, Koprivova A, Kopriva S (2017) The role of soil microorganisms in plant mineral nutrition\u2014current knowledge and future directions. Front Plant Sci 8:1617","journal-title":"Front Plant Sci"},{"key":"4028_CR52","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2018.00012","volume":"9","author":"SK Jalmi","year":"2018","unstructured":"Jalmi SK, Bhagat PK, Verma D, Noryang S, Tayyeba S, Singh K, Sharma D, Sinha AK (2018) Traversing the links between heavy metal stress and plant signaling. Front Plant Sci 9:12","journal-title":"Front Plant Sci"},{"issue":"3","key":"4028_CR53","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1080\/01490451.2024.2307899","volume":"41","author":"I Jamir","year":"2024","unstructured":"Jamir I, Ezung LY, Merry L, Tikendra L, Devi RS, Nongdam P (2024) Heavy metals clean up: the application of fungi for biosorption. Geomicrobiol J 41(3):201\u2013212","journal-title":"Geomicrobiol J"},{"issue":"1","key":"4028_CR54","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s00204-024-03903-2","volume":"99","author":"K Jomova","year":"2025","unstructured":"Jomova K, Alomar SY, Nepovimova E, Kuca K, Valko M (2025) Heavy metals: toxicity and human health effects. Arch Toxicol 99(1):153\u2013209","journal-title":"Arch Toxicol"},{"issue":"4","key":"4028_CR55","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1007\/s12088-011-0110-9","volume":"51","author":"PK Joshi","year":"2011","unstructured":"Joshi PK, Swarup A, Maheshwari S, Kumar R, Singh N (2011) Bioremediation of heavy metals in liquid media through fungi isolated from contaminated sources. Indian J Microbiol 51(4):482\u2013487","journal-title":"Indian J Microbiol"},{"key":"4028_CR56","doi-asserted-by":"publisher","DOI":"10.3389\/fenvs.2024.1397850","volume":"12","author":"A Karnwal","year":"2024","unstructured":"Karnwal A, Martolia S, Dohroo A, Al-Tawaha ARMS, Malik T (2024) Exploring bioremediation strategies for heavy metals and POPs pollution: the role of microbes, plants, and nanotechnology. Front Environ Sci 12:1397850","journal-title":"Front Environ Sci"},{"issue":"3","key":"4028_CR57","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S1002-0160(20)60091-1","volume":"31","author":"M Khalid","year":"2021","unstructured":"Khalid M, Saeed UR, Hassani D, Hayat K, Pei Z, Nan H (2021) Advances in fungal-assisted phytoremediation of heavy metals: a review. Pedosphere 31(3):475\u2013495","journal-title":"Pedosphere"},{"key":"4028_CR58","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.1039329","volume":"13","author":"MA Khoso","year":"2022","unstructured":"Khoso MA, Hussain A, Ritonga FN, Ali Q, Channa MM, Alshegaihi RM, Meng Q, Ali M, Zaman W, Brohi RD, Liu F, Manghwar H (2022) WRKY transcription factors (TFs): molecular switches to regulate drought, temperature, and salinity stresses in plants. Front Plant Sci 13:1039329","journal-title":"Front Plant Sci"},{"issue":"1","key":"4028_CR59","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s10534-018-00164-2","volume":"32","author":"S Khullar","year":"2019","unstructured":"Khullar S, Reddy MS (2019) Cadmium induced glutathione bioaccumulation mediated by \u03b3-glutamylcysteine synthetase in ectomycorrhizal fungus Hebeloma cylindrosporum. Biometals 32(1):101\u2013110","journal-title":"Biometals"},{"issue":"4","key":"4028_CR60","doi-asserted-by":"publisher","first-page":"12326","DOI":"10.33263\/BRIAC114.1232612347","volume":"11","author":"RA Kristanti","year":"2021","unstructured":"Kristanti RA, Ngu WJ, Yuniarto A, Hadibarata T (2021) Rhizofiltration for removal of inorganic and organic pollutants in groundwater: a review. Biointerface Res Appl Chem 11(4):12326\u201312347","journal-title":"Biointerface Res Appl Chem"},{"key":"4028_CR61","first-page":"38","volume":"1","author":"V Kumar","year":"2019","unstructured":"Kumar V, Singh J, Kumar P (2019) Heavy metals accumulation in crop plants: sources, response mechanisms, stress tolerance and their effects. Contam Agri Environ Heal Risks Remediat 1:38","journal-title":"Contam Agri Environ Heal Risks Remediat"},{"issue":"19","key":"4028_CR62","volume":"11","author":"M Labudda","year":"2022","unstructured":"Labudda M, Dziurka K, Fidler J, Gietler M, Rybarczyk-P\u0142o\u0144ska A, Nykiel M, Prabucka B, Morkunas I, Muszy\u0144ska E (2022) The alleviation of metal stress nuisance for plants\u2014a review of promising solutions in the face of environmental challenges. Plants (Basel) 11(19):2544","journal-title":"Plants (Basel)"},{"issue":"1","key":"4028_CR63","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1186\/s13765-021-00660-z","volume":"64","author":"Y Lee","year":"2021","unstructured":"Lee Y, Jang J, Jeon Y, Kim H, Jang G, Yoon Y (2021) Assessing the effects of accumulated Cd (II) on seed germination and root development of Arabidopsis thaliana. Appl Biol Chem 64(1):87","journal-title":"Appl Biol Chem"},{"issue":"7","key":"4028_CR64","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1016\/j.chemosphere.2008.12.068","volume":"75","author":"HF Li","year":"2009","unstructured":"Li HF, Gray C, Mico C, Zhao FJ, McGrath SP (2009) Phytotoxicity and bioavailability of cobalt to plants in a range of soils. Chemosphere 75(7):979\u2013986","journal-title":"Chemosphere"},{"key":"4028_CR65","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.976311","volume":"13","author":"X Li","year":"2022","unstructured":"Li X, Zhang L, Ren H, Wang X, Mi F (2022) Zinc toxicity response in Ceratoides arborescens and identification of CaMTP, a novel zinc transporter. Front Plant Sci 13:976311. https:\/\/doi.org\/10.3389\/fpls.2022.976311","journal-title":"Front Plant Sci"},{"issue":"10","key":"4028_CR66","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1016\/j.cub.2024.04.005","volume":"34","author":"Q Li","year":"2024","unstructured":"Li Q, Zhang M, Wei B, Lan W, Wang Q, Chen C, Zhao H, Liu D, Gadd GM (2024) Fungal biomineralization of toxic metals accelerates organic pollutant removal. Curr Biol 34(10):2077\u20132084","journal-title":"Curr Biol"},{"issue":"3","key":"4028_CR67","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1134\/S1021443726601047","volume":"73","author":"W Li","year":"2026","unstructured":"Li W, Sun XY, Cui JL (2026) Research progress on endophytic fungi promoting seed germination: a potential breeding approach. Russ J Plant Physiol 73(3):121","journal-title":"Russ J Plant Physiol"},{"issue":"1","key":"4028_CR68","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12826-x","volume":"10","author":"L Liu","year":"2019","unstructured":"Liu L, Gueguen-Chaignon V, Gon\u00e7alves IR, Rascle C, Rigault M, Dellagi A, Loisel E, Poussereau N, Rodrigue A, Terradot L, Condemine G (2019) A secreted metal-binding protein protects necrotrophic phytopathogens from reactive oxygen species. Nat Commun 10(1):4853","journal-title":"Nat Commun"},{"issue":"6","key":"4028_CR69","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.2134\/jeq2001.1919","volume":"30","author":"E Lombi","year":"2001","unstructured":"Lombi E, Zhao FJ, Dunham SJ, McGrath SP (2001) Phytoremediation of heavy metal\u2013contaminated soils: natural hyperaccumulation versus chemically enhanced phytoextraction. J Environ Qual 30(6):1919\u20131926","journal-title":"J Environ Qual"},{"issue":"8","key":"4028_CR70","doi-asserted-by":"publisher","first-page":"703","DOI":"10.2175\/106143017X14839994523749","volume":"89","author":"DD Long","year":"2017","unstructured":"Long DD, Wang Q, Han JR (2017) Biosorption of Copper from Aqueous Solutions by Sclerotiogenic Aspergillus oryzae G15. Water Environ Res 89(8):703\u2013713","journal-title":"Water Environ Res"},{"key":"4028_CR71","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.plgene.2017.04.006","volume":"11","author":"M Maleki","year":"2017","unstructured":"Maleki M, Ghorbanpour M, Kariman K (2017) Physiological and antioxidative responses of medicinal plants exposed to heavy metals stress. Plant Gene 11:247\u2013254","journal-title":"Plant Gene"},{"issue":"16","key":"4028_CR72","volume":"12","author":"S Mansoor","year":"2023","unstructured":"Mansoor S, Ali A, Kour N, Bornhorst J, AlHarbi K, Rinklebe J, Abd El Moneim D, Ahmad P, Chung YS (2023) Heavy metal induced oxidative stress mitigation and ROS scavenging in plants. Plants (Basel) 12(16):3003","journal-title":"Plants (Basel)"},{"key":"4028_CR73","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/B978-0-323-85665-2.00021-2","volume-title":"Plant perspectives to global climate changes","author":"Z Manzoor","year":"2022","unstructured":"Manzoor Z, Hassan Z, Ul-Allah S, Khan AA, Sattar A, Shahzad U, Hussain M (2022) Transcription factors involved in plant responses to heavy metal stress adaptation. Plant perspectives to global climate changes. Academic Press, pp 221\u2013231"},{"issue":"2","key":"4028_CR74","volume":"12","author":"MD Mashabela","year":"2023","unstructured":"Mashabela MD, Masamba P, Kappo AP (2023) Applications of metabolomics for the elucidation of abiotic stress tolerance in plants: a special focus on osmotic stress and heavy metal toxicity. Plants (Basel) 12(2):269","journal-title":"Plants (Basel)"},{"issue":"12","key":"4028_CR75","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00203-026-05187-9","volume":"208","author":"S Maurya","year":"2026","unstructured":"Maurya S, Sharma P, Yadav BNS, Gupta GP, Tiwari N, Yadav RK (2026) Fungi to the rescue: recent advances, mechanistic insights and omics-based perspectives in heavy metal mycoremediation. Arch Microbiol 208(12):643","journal-title":"Arch Microbiol"},{"key":"4028_CR76","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2022.129121","volume":"436","author":"YT Meng","year":"2022","unstructured":"Meng YT, Zhang XL, Wu Q, Shen RF, Zhu XF (2022) Transcription factor ANAC004 enhances Cd tolerance in Arabidopsis thaliana by regulating cell wall fixation, translocation and vacuolar detoxification of Cd, ABA accumulation and antioxidant capacity. J Hazard Mater 436:129121","journal-title":"J Hazard Mater"},{"issue":"7","key":"4028_CR77","doi-asserted-by":"publisher","first-page":"2497","DOI":"10.1007\/s11356-026-37486-5","volume":"33","author":"MA Meziane","year":"2026","unstructured":"Meziane MA, Deli\u00e8ge JF, Sadougui I, Yahyaoui MI, Mehane L, Taibi M, Elbouzidi A, Bellaouchi R, El Guerrouj B, Chafi A, Saalaoui E, Asehraou A (2026) Microbial strategies for heavy metal remediation: mechanisms, challenges, and promising approaches for metal detoxification. Environ Sci Pollut Res 33(7):2497\u20132516","journal-title":"Environ Sci Pollut Res"},{"key":"4028_CR78","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.chemosphere.2016.12.093","volume":"171","author":"M Mnasri","year":"2017","unstructured":"Mnasri M, Janou\u0161kov\u00e1 M, Rydlov\u00e1 J, Abdelly C, Ghnaya T (2017) Comparison of arbuscular mycorrhizal fungal effects on the heavy metal uptake of a host and a non-host plant species in contact with extraradical mycelial network. Chemosphere 171:476\u2013484","journal-title":"Chemosphere"},{"issue":"1","key":"4028_CR79","doi-asserted-by":"publisher","DOI":"10.1186\/s40643-025-00930-4","volume":"12","author":"HI Mohamed","year":"2025","unstructured":"Mohamed HI, Ullah I, Toor MD, Tanveer NA, Din MMU, Basit A, Sultan Y, Muhammad M, Rehman MU (2025) Heavy metals toxicity in plants: understanding mechanisms and developing coping strategies for remediation: a review. Bioresources Bioprocess 12(1):95. https:\/\/doi.org\/10.1186\/s40643-025-00930-4","journal-title":"Bioresources Bioprocess"},{"issue":"5","key":"4028_CR80","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12911\/22998993\/157567","volume":"24","author":"R Muksy","year":"2023","unstructured":"Muksy R, Kolo K, Abdullah SM (2023) Bacterial and fungal-mineral interactions and their application in bioremediation\u2013a review. J Ecol Eng 24(5):1\u201313","journal-title":"J Ecol Eng"},{"issue":"3","key":"4028_CR81","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s10311-010-0297-8","volume":"8","author":"PC Nagajyoti","year":"2010","unstructured":"Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8(3):199\u2013216","journal-title":"Environ Chem Lett"},{"issue":"1","key":"4028_CR82","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s44331-026-00013-x","volume":"2","author":"RD Nagar","year":"2026","unstructured":"Nagar RD, Gupta J, Gurung P, Kaur H, Gupta A, Srivastava S (2026) Nano-enabled delivery of plant polyphenols: a climate-resilient strategy for enhancing crop stress tolerance and productivity. Biosci Nanotechnol 2(1):5","journal-title":"Biosci Nanotechnol"},{"key":"4028_CR83","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/978-3-319-57849-1_12","volume-title":"Mycorrhiza-eco-physiology, secondary metabolites, nanomaterials","author":"M Nath","year":"2017","unstructured":"Nath M, Bhatt D, Prasad R, Tuteja N (2017) Reactive oxygen species (ROS) metabolism and signaling in plant-mycorrhizal association under biotic and abiotic stress conditions. Mycorrhiza-eco-physiology, secondary metabolites, nanomaterials. Springer International Publishing, Cham, pp 223\u2013232"},{"issue":"8","key":"4028_CR84","doi-asserted-by":"publisher","first-page":"2793","DOI":"10.1111\/pce.14926","volume":"47","author":"LA Niekerk","year":"2024","unstructured":"Niekerk LA, Gokul A, Basson G, Badiwe M, Nkomo M, Klein A, Keyster M (2024) Heavy metal stress and mitogen activated kinase transcription factors in plants: exploring heavy metal\u2010ROS influences on plant signalling pathways. Plant Cell Environ 47(8):2793\u20132810","journal-title":"Plant Cell Environ"},{"issue":"1","key":"4028_CR85","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.bjm.2017.06.003","volume":"49","author":"OG Oladipo","year":"2018","unstructured":"Oladipo OG, Awotoye OO, Olayinka A, Bezuidenhout CC, Maboeta MS (2018) Heavy metal tolerance traits of filamentous fungi isolated from gold and gemstone mining sites. Braz J Microbiol 49(1):29\u201337. https:\/\/doi.org\/10.1016\/j.bjm.2017.06.003","journal-title":"Braz J Microbiol"},{"issue":"6","key":"4028_CR86","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.jplph.2004.09.014","volume":"162","author":"F Ouziad","year":"2005","unstructured":"Ouziad F, Hildebrandt U, Schmelzer E, Bothe H (2005) Differential gene expressions in arbuscular mycorrhizal-colonized tomato grown under heavy metal stress. J Plant Physiol 162(6):634\u2013649. https:\/\/doi.org\/10.1016\/j.jplph.2004.09.014","journal-title":"J Plant Physiol"},{"issue":"12","key":"4028_CR87","doi-asserted-by":"publisher","DOI":"10.3390\/horticulturae8121181","volume":"8","author":"J Pacheco-Trejo","year":"2022","unstructured":"Pacheco-Trejo J, Aquino-Torres E, Reyes-Santamar\u00eda MI, Islas-Pelcastre M, P\u00e9rez-R\u00edos SR, Madariaga-Navarrete A, Saucedo-Garc\u00eda M (2022) Plant defensive responses triggered by Trichoderma spp. as tools to face stressful conditions. Horticulturae 8(12):1181","journal-title":"Horticulturae"},{"key":"4028_CR88","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1186\/s12870-026-08997-7","volume":"26","author":"B Panahi","year":"2026","unstructured":"Panahi B, Hamid R, Ghorbanzadeh Z, Lakhani KG, Jacob F (2026) Comprehensive analysis of TGA genes in barley: structure, evolution, and stress-responsive expression. BMC Plant Biol 26:1210","journal-title":"BMC Plant Biol"},{"issue":"2","key":"4028_CR89","first-page":"101","volume":"2","author":"HP Parewa","year":"2014","unstructured":"Parewa HP, Yadav J, Rakshit A, Meena VS, Karthikeyan N (2014) Plant growth promoting rhizobacteria enhance growth and nutrient uptake of crops. Agric Sustain Dev 2(2):101\u2013116","journal-title":"Agric Sustain Dev"},{"issue":"9","key":"4028_CR90","doi-asserted-by":"publisher","first-page":"5855","DOI":"10.1007\/s00344-023-10971-8","volume":"42","author":"N Pasari","year":"2023","unstructured":"Pasari N, Gazara RK, Singh J, Verma PK (2023) Genome-wide identification of SWEET genes in Cicer arietinum and modulation of its expression in endophytic interactions with Serendipita indica. J Plant Growth Regul 42(9):5855\u20135868","journal-title":"J Plant Growth Regul"},{"issue":"5","key":"4028_CR91","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1080\/02757540.2026.2661739","volume":"42","author":"DK Patra","year":"2026","unstructured":"Patra DK, Nayak M, Pradhan C, Patra HK (2026a) Heavy metals tolerance and toxic effects on plants: a review. Chem Ecol 42(5):640\u2013672","journal-title":"Chem Ecol"},{"key":"4028_CR92","doi-asserted-by":"crossref","unstructured":"Patra, H. K., Thatoi, H., Mohapatra, J., Mohanty, M., Patra, D. K., Nayak, M., Das, A. B (2026) Integrated approaches for attenuation of Cr (VI) toxicity in chromite mine waste. Soil and Sediment Contamination: An International Journal, 1\u201325","DOI":"10.1080\/15320383.2026.2636218"},{"issue":"35","key":"4028_CR93","doi-asserted-by":"publisher","first-page":"7190","DOI":"10.2174\/0929867328666210324161205","volume":"28","author":"M Peana","year":"2021","unstructured":"Peana M, Pelucelli A, Medici S, Cappai R, Nurchi VM, Zoroddu MA (2021) Metal toxicity and speciation: a review. Curr Med Chem 28(35):7190\u20137208","journal-title":"Curr Med Chem"},{"key":"4028_CR94","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.123609","volume":"403","author":"N Pehlivan","year":"2021","unstructured":"Pehlivan N, Gedik K, Eltem R, Terzi E (2021) Dynamic interactions of Trichoderma harzianum TS 143 from an old mining site in Turkey for potent metal (oid) s phytoextraction and bioenergy crop farming. J Hazard Mater 403:123609","journal-title":"J Hazard Mater"},{"issue":"9","key":"4028_CR95","first-page":"473","volume":"72","author":"DH Prajapati","year":"2020","unstructured":"Prajapati DH, Ausma T, De Boer J, Hawkesford M, De Kok LJ (2020) Nickel toxicity in Brassica rapa seedlings-Impact on sulfur metabolism and mineral nutrient content. J fur Kulturpflanzen-J Cultiv Plants 72(9):473\u2013478","journal-title":"J fur Kulturpflanzen-J Cultiv Plants"},{"issue":"1","key":"4028_CR96","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1186\/s12866-025-04000-9","volume":"25","author":"AM Rabab","year":"2025","unstructured":"Rabab AM, Asmaa ST, Asmaa HM, Shereen AS (2025) Adaptability assessment of Aspergillus niger and Aspergillus terreus isolated from long-term municipal\/industrial effluent-irrigated soils to cadmium stress. BMC Microbiol 25(1):297","journal-title":"BMC Microbiol"},{"key":"4028_CR97","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-821925-6.00015-0","author":"D Ramya","year":"2021","unstructured":"Ramya D, Kiruba NJM, Thatheyus AJ (2021) Biosorption of heavy metals using fungal biosorbents\u2013a review. Fungi Bio-Prospects Sustain Agricult Environ Nano-Technol. https:\/\/doi.org\/10.1016\/B978-0-12-821925-6.00015-0","journal-title":"Fungi Bio-Prospects Sustain Agricult Environ Nano-Technol"},{"issue":"8","key":"4028_CR98","doi-asserted-by":"publisher","first-page":"2446","DOI":"10.1111\/1462-2920.13149","volume":"18","author":"MS Reddy","year":"2016","unstructured":"Reddy MS, Kour M, Aggarwal S, Ahuja S, Marmeisse R, Fraissinet-Tachet L (2016) Metal induction of a P isolithus albus metallothionein and its potential involvement in heavy metal tolerance during mycorrhizal symbiosis. Environ Microbiol 18(8):2446\u20132454","journal-title":"Environ Microbiol"},{"issue":"3","key":"4028_CR99","doi-asserted-by":"publisher","first-page":"225","DOI":"10.3390\/jof7030225","volume":"7","author":"JR Robinson","year":"2021","unstructured":"Robinson JR, Isikhuemhen OS, Anike FN (2021) Fungal\u2013metal interactions: a review of toxicity and homeostasis. J Fungi 7(3):225","journal-title":"J Fungi"},{"key":"4028_CR100","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.envexpbot.2018.04.008","volume":"151","author":"M Ronzan","year":"2018","unstructured":"Ronzan M, Piacentini D, Fattorini L, Della Rovere F, Eiche E, Riemann M, Altamura MM, Falasca G (2018) Cadmium and arsenic affect root development in Oryza sativa L. negatively interacting with auxin. Environ Exp Bot 151:64\u201375","journal-title":"Environ Exp Bot"},{"issue":"4","key":"4028_CR101","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1002\/tqem.22139","volume":"33","author":"B Roy","year":"2024","unstructured":"Roy B, Maitra D, Sarkar S, Podder R, Das T, Ghosh J, Mitra AK (2024) Biofilm and metallothioneins: a dual approach to bioremediate the heavy metal menace. Environ Qual Manage 33(4):659\u2013676","journal-title":"Environ Qual Manage"},{"issue":"19","key":"4028_CR102","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221910529","volume":"22","author":"Q Saeed","year":"2021","unstructured":"Saeed Q, Xiukang W, Haider FU, Ku\u010derik J, Mumtaz MZ, Holatko J, Naseem M, Kintl A, Ejaz M, Naveed M, Brtnicky M, Mustafa A (2021) Rhizosphere bacteria in plant growth promotion, biocontrol, and bioremediation of contaminated sites: a comprehensive review of effects and mechanisms. Int J Mol Sci 22(19):10529","journal-title":"Int J Mol Sci"},{"issue":"1","key":"4028_CR103","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.jbiotec.2005.07.002","volume":"121","author":"D Santhiya","year":"2006","unstructured":"Santhiya D, Ting YP (2006) Use of adapted Aspergillus niger in the bioleaching of spent refinery processing catalyst. J Biotechnol 121(1):62\u201374","journal-title":"J Biotechnol"},{"key":"4028_CR104","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/B978-0-443-27324-7.00018-5","volume-title":"Biotic stress tolerance in horticultural crops","author":"G Santoyo","year":"2025","unstructured":"Santoyo G, Kumar A, del Carmen Orozco-Mosqueda M, Guzm\u00e1n-Guzm\u00e1n P (2025) The Trichoderma strategy to mitigate stress in horticulture crops. Biotic stress tolerance in horticultural crops. Woodhead Publishing, pp 297\u2013308"},{"issue":"5","key":"4028_CR105","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1080\/02757540.2018.1437150","volume":"34","author":"A Sarkar","year":"2018","unstructured":"Sarkar A, Asaeda T, Wang Q, Kaneko Y, Rashid MH (2018) Arbuscular mycorrhiza confers lead tolerance and uptake in Miscanthus sacchariflorus. Chem Ecol 34(5):454\u2013469","journal-title":"Chem Ecol"},{"key":"4028_CR106","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1016\/j.chemosphere.2016.12.116","volume":"171","author":"N Sarwar","year":"2017","unstructured":"Sarwar N, Imran M, Shaheen MR, Ishaque W, Kamran MA, Matloob A, Rehim A, Hussain S (2017) Phytoremediation strategies for soils contaminated with heavy metals: modifications and future perspectives. Chemosphere 171:710\u2013721","journal-title":"Chemosphere"},{"issue":"3","key":"4028_CR107","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24032430","volume":"24","author":"IV Seregin","year":"2023","unstructured":"Seregin IV, Kozhevnikova AD (2023) Phytochelatins: sulfur-containing metal (loid)-chelating ligands in plants. Int J Mol Sci 24(3):2430","journal-title":"Int J Mol Sci"},{"issue":"4","key":"4028_CR108","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1023\/B:RUPP.0000035747.42399.84","volume":"51","author":"IV Seregin","year":"2004","unstructured":"Seregin IV, Shpigun LK, Ivanov VB (2004) Distribution and toxic effects of cadmium and lead on maize roots. Russ J Plant Physiol 51(4):525\u2013533","journal-title":"Russ J Plant Physiol"},{"issue":"7","key":"4028_CR109","doi-asserted-by":"publisher","DOI":"10.1007\/s13762-026-07311-0","volume":"23","author":"AM Shah","year":"2026","unstructured":"Shah AM, Manzoor S, Altaf MT, Bayramo\u011flu Z, Popescu SM, Mansoor S (2026) Regulatory mechanisms and signalling cascades in plant adaptation to heavy metal toxicity. Int J Environ Sci Technol 23(7):510","journal-title":"Int J Environ Sci Technol"},{"key":"4028_CR110","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-803158-2.00010-","author":"R Sharma","year":"2016","unstructured":"Sharma R, Bhardwaj R, Handa N, Gautam V, Kohli SK, Bali S, Vig AP (2016) Responses of phytochelatins and metallothioneins in alleviation of heavy metal stress in plants: an overview. Plant Metal Interact. https:\/\/doi.org\/10.1016\/B978-0-12-803158-2.00010-","journal-title":"Plant Metal Interact"},{"key":"4028_CR111","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-16-7981-0_1","author":"SK Sharma","year":"2022","unstructured":"Sharma SK, Singh D, Pandey H, Jatav RB, Singh V, Pandey D (2022) An overview of roles of enzymatic and nonenzymatic antioxidants in plant. Antioxid Defense Plants Mol Basis Regul. https:\/\/doi.org\/10.1007\/978-981-16-7981-0_1","journal-title":"Antioxid Defense Plants Mol Basis Regul"},{"issue":"3","key":"4028_CR112","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1111\/pce.13457","volume":"42","author":"Y Sheng","year":"2019","unstructured":"Sheng Y, Yan X, Huang Y, Han Y, Zhang C, Ren Y, Cao S (2019) The WRKY transcription factor, WRKY13, activates PDR8 expression to positively regulate cadmium tolerance in Arabidopsis. Plant, Cell Environ 42(3):891\u2013903","journal-title":"Plant, Cell Environ"},{"issue":"4","key":"4028_CR113","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1111\/pce.13471","volume":"42","author":"W Shi","year":"2019","unstructured":"Shi W, Zhang Y, Chen S, Polle A, Rennenberg H, Luo ZB (2019) Physiological and molecular mechanisms of heavy metal accumulation in nonmycorrhizal versus mycorrhizal plants. Plant Cell Environ 42(4):1087\u20131103","journal-title":"Plant Cell Environ"},{"issue":"4","key":"4028_CR114","first-page":"191","volume":"8","author":"I Singh","year":"2018","unstructured":"Singh I (2018) Plant growth promoting rhizobacteria (PGPR) and their various mechanisms for plant growth enhancement in stressful conditions: a review. Eur J Biol Res 8(4):191","journal-title":"Eur J Biol Res"},{"issue":"4","key":"4028_CR115","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/s00027-024-01121-7","volume":"86","author":"G Singh","year":"2024","unstructured":"Singh G, Sharma S (2024) Heavy metal contamination in fish: sources, mechanisms and consequences: G Singh and s Sharma. Aquatic Sci 86(4):107","journal-title":"Aquatic Sci"},{"issue":"1-2","key":"4028_CR116","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.gene.2011.03.001","volume":"480","author":"JS Singh","year":"2011","unstructured":"Singh JS, Abhilash PC, Singh HB, Singh RP, Singh DP (2011) Genetically engineered bacteria: an emerging tool for environmental remediation and future research perspectives. Gene 480(1\u20132):1\u20139","journal-title":"Gene"},{"key":"4028_CR117","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/B978-0-12-818095-2.00009-6","volume-title":"Abatement of environmental pollutants","author":"RK Singh","year":"2020","unstructured":"Singh RK, Tripathi R, Ranjan A, Srivastava AK (2020) Fungi as potential candidates for bioremediation. Abatement of environmental pollutants. Elsevier, pp 177\u2013191"},{"issue":"49","key":"4028_CR118","doi-asserted-by":"publisher","first-page":"21187","DOI":"10.1073\/pnas.1013964107","volume":"107","author":"WY Song","year":"2010","unstructured":"Song WY, Park J, Mendoza-C\u00f3zatl DG, Suter-Grotemeyer M, Shim D, H\u00f6rtensteiner S, Geisler M, Weder B, Rea PA, Rentsch D, Schroeder JI, Lee Y, Martinoia E (2010) Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. Proc Natl Acad Sci U S A 107(49):21187\u201321192","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4028_CR119","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2022.153136","volume":"469","author":"Q Sun","year":"2022","unstructured":"Sun Q, Li Y, Shi L, Hussain R, Mehmood K, Tang Z, Zhang H (2022) Heavy metals induced mitochondrial dysfunction in animals: molecular mechanism of toxicity. Toxicology 469:153136","journal-title":"Toxicology"},{"key":"4028_CR120","doi-asserted-by":"publisher","first-page":"547","DOI":"10.3389\/fpls.2014.00547","volume":"5","author":"E Tamayo","year":"2014","unstructured":"Tamayo E, G\u00f3mez-Gallego T, Azc\u00f3n-Aguilar C, Ferrol N (2014) Genome-wide analysis of copper, iron and zinc transporters in the arbuscular mycorrhizal fungus Rhizophagus irregularis. Front Plant Sci 5:547","journal-title":"Front Plant Sci"},{"issue":"5","key":"4028_CR121","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.2134\/jeq2002.1671","volume":"31","author":"C Tu","year":"2002","unstructured":"Tu C, Ma LQ, Bondada B (2002) Arsenic accumulation in the hyperaccumulator Chinese brake and its utilization potential for phytoremediation. J Environ Qual 31(5):1671\u20131675","journal-title":"J Environ Qual"},{"issue":"13","key":"4028_CR122","doi-asserted-by":"publisher","first-page":"5827","DOI":"10.1007\/s11356-026-37638-7","volume":"33","author":"S Viswanathan","year":"2026","unstructured":"Viswanathan S, Nagella P (2026) Impact of mercury toxicity on plant growth and development: an overview on physiological, biochemical, and mitigation aspects. Environ Sci Pollut Res Int 33(13):5827\u20135847. https:\/\/doi.org\/10.1007\/s11356-026-37638-7","journal-title":"Environ Sci Pollut Res Int"},{"issue":"1","key":"4028_CR123","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11104-022-05621-z","volume":"481","author":"F Wang","year":"2022","unstructured":"Wang F, Zhang L, Zhou J, Rengel Z, George TS, Feng G (2022a) Exploring the secrets of hyphosphere of arbuscular mycorrhizal fungi: processes and ecological functions. Plant Soil 481(1):1\u201322","journal-title":"Plant Soil"},{"issue":"1","key":"4028_CR124","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-022-03456-5","volume":"22","author":"X Wang","year":"2022","unstructured":"Wang X, Liang J, Liu Z, Kuang Y, Han L, Chen H, Xie X, Hu W, Tang M (2022b) Transcriptional regulation of metal metabolism-and nutrient absorption-related genes in Eucalyptus grandis by arbuscular mycorrhizal fungi at different zinc concentrations. BMC Plant Biol 22(1):76","journal-title":"BMC Plant Biol"},{"key":"4028_CR125","volume-title":"Guidelines for drinking-water quality: fourth edition incorporating the first and second addenda","author":"World Health Organisation","year":"2022","unstructured":"World Health Organisation (2022) Guidelines for drinking-water quality: fourth edition incorporating the first and second addenda. World Health Organization"},{"issue":"1","key":"4028_CR126","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s11104-009-0151-6","volume":"325","author":"J Wu","year":"2009","unstructured":"Wu J, Zhao FJ, Ghandilyan A, Logoteta B, Guzman MO, Schat H, Wang X, Aarts MGM, Aarts MG (2009) Identification and functional analysis of two ZIP metal transporters of the hyperaccumulator Thlaspi caerulescens. Plant Soil 325(1):79\u201395","journal-title":"Plant Soil"},{"issue":"1-3","key":"4028_CR127","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jhazmat.2009.09.113","volume":"174","author":"G Wu","year":"2010","unstructured":"Wu G, Kang H, Zhang X, Shao H, Chu L, Ruan C (2010) A critical review on the bio-removal of hazardous heavy metals from contaminated soils: issues, progress, eco-environmental concerns and opportunities. J Hazard Mater 174(1\u20133):1\u20138","journal-title":"J Hazard Mater"},{"issue":"1","key":"4028_CR128","doi-asserted-by":"publisher","DOI":"10.1186\/s12284-014-0008-3","volume":"7","author":"LB Wu","year":"2014","unstructured":"Wu LB, Shhadi MY, Gregorio G, Matthus E, Becker M, Frei M (2014) Genetic and physiological analysis of tolerance to acute iron toxicity in rice. Rice (New York, Ny) 7(1):8. https:\/\/doi.org\/10.1186\/s12284-014-0008-3","journal-title":"Rice (New York, Ny)"},{"key":"4028_CR129","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2026.119885","volume":"311","author":"Y Xu","year":"2026","unstructured":"Xu Y, Ke J, Zhang Y, Chen X, Wang Y (2026) Harnessing AMF-plant-microbe systems for heavy metal remediation. Ecotoxicol Environ Saf 311:119885","journal-title":"Ecotoxicol Environ Saf"},{"key":"4028_CR130","doi-asserted-by":"publisher","DOI":"10.1080\/15226514.2026.2705292","author":"P Yadav","year":"2026","unstructured":"Yadav P, Jha S, Gahlawat D, Sharma A, Singh S (2026) Salicylic acid and heavy metal stress: current understanding and emerging perspectives. Int J Phytoremediation. https:\/\/doi.org\/10.1080\/15226514.2026.2705292","journal-title":"Int J Phytoremediation"},{"key":"4028_CR131","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/B978-0-444-63501-3.00014-4","volume-title":"New and future developments in microbial biotechnology and bioengineering","author":"A Zehra","year":"2018","unstructured":"Zehra A, Dubey MK, Meena M, Aamir M, Patel CB, Upadhyay RS (2018) Role of Penicillium species in bioremediation processes. New and future developments in microbial biotechnology and bioengineering. Elsevier, pp 247\u2013260"},{"issue":"9","key":"4028_CR132","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1080\/15226514.2019.1577353","volume":"21","author":"F Zhan","year":"2019","unstructured":"Zhan F, Li B, Jiang M, Li T, He Y, Li Y, Wang Y (2019) Effects of arbuscular mycorrhizal fungi on the growth and heavy metal accumulation of bermudagrass [Cynodon dactylon (L.) Pers.] grown in a lead\u2013zinc mine wasteland. Int J Phytoremediation 21(9):849\u2013856","journal-title":"Int J Phytoremediation"},{"key":"4028_CR133","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3389\/fpls.2018.00107","volume":"9","author":"X Zhang","year":"2018","unstructured":"Zhang X, Rui H, Zhang F, Hu Z, Xia Y, Shen Z (2018) Overexpression of a functional Vicia sativa PCS1 homolog increases cadmium tolerance and phytochelatins synthesis in Arabidopsis. Front Plant Sci 9:107","journal-title":"Front Plant Sci"},{"key":"4028_CR134","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01428","volume":"11","author":"Q Zhang","year":"2020","unstructured":"Zhang Q, Gong M, Liu K, Chen Y, Yuan J, Chang Q (2020) Rhizoglomus intraradices improves plant growth, root morphology and phytohormone balance of Robinia pseudoacacia in arsenic-contaminated soils. Front Microbiol 11:1428","journal-title":"Front Microbiol"},{"key":"4028_CR135","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3389\/fpls.2017.00272","volume":"8","author":"J Zhao","year":"2017","unstructured":"Zhao J, Wang W, Zhou H, Wang R, Zhang P, Wang H, Pan X, Xu J (2017) Manganese toxicity inhibited root growth by disrupting auxin biosynthesis and transport in Arabidopsis. Front Plant Sci 8:272. https:\/\/doi.org\/10.3389\/fpls.2017.00272","journal-title":"Front Plant Sci"},{"issue":"12","key":"4028_CR136","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1080\/15226514.2023.2176466","volume":"25","author":"J Zheng","year":"2023","unstructured":"Zheng J, Xie X, Li C, Wang H, Yu Y, Huang B (2023) Regulation mechanism of plant response to heavy metal stress mediated by endophytic fungi. Int J Phytoremediation 25(12):1596\u20131613","journal-title":"Int J Phytoremediation"}],"container-title":["Plant Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00299-026-04028-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00299-026-04028-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00299-026-04028-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:02:20Z","timestamp":1792800140000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00299-026-04028-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,24]]},"references-count":136,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["4028"],"URL":"https:\/\/doi.org\/10.1007\/s00299-026-04028-9","relation":{},"ISSN":["0721-7714","1432-203X"],"issn-type":[{"value":"0721-7714","type":"print"},{"value":"1432-203X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,24]]},"assertion":[{"value":"23 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have not disclosed any competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"342"}}