{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T21:23:13Z","timestamp":1774560193541,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2005,12,13]],"date-time":"2005-12-13T00:00:00Z","timestamp":1134432000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2006,4,10]]},"DOI":"10.1007\/s00330-005-0064-6","type":"journal-article","created":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T14:06:34Z","timestamp":1134396394000},"page":"1050-1053","source":"Crossref","is-referenced-by-count":31,"title":["Development of water-soluble metallofullerenes as X-ray contrast media"],"prefix":"10.1007","volume":"16","author":[{"given":"Akihiko","family":"Miyamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruya","family":"Okimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisanori","family":"Shinohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuta","family":"Shibamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,12,13]]},"reference":[{"key":"64_CR1","doi-asserted-by":"crossref","unstructured":"Morcos SK, Thomsen HS, Webb JAW and ESUR Contrast Media Safety Committee (1999) Contrast media-induced nephrotoxicity: a consensus report. Eur Radiol 9:1602\u20131613. DOI 10.1007\/s003300050894","DOI":"10.1007\/s003300050894"},{"key":"64_CR2","doi-asserted-by":"crossref","unstructured":"Thomsen HS, Morcos SK and Members of Contrast Media Safety Committee of ESUR (2005) In which patients should serum creatinine be measured before iodinated contrast medium administration? Eur Radiol 15:749\u2013754. DOI 10.1007\/s00330-004-2591-y","DOI":"10.1007\/s00330-004-2591-y"},{"key":"64_CR3","doi-asserted-by":"crossref","unstructured":"Van der Molen AJ, Thomsen HS, Morcos SK, ESUR Contrast Media Safety Committee (2004) Effect of iodinated contrast media on thyroid function in adults. Eur Radiol 14:902\u2013907. DOI 10.1007\/s00330-004-2238-z","DOI":"10.1007\/s00330-004-2238-z"},{"key":"64_CR4","doi-asserted-by":"crossref","unstructured":"Morcos SK, Thomsen HS, Exley CM and Members of Contrast Media Safety Committee of ESUR (2005) Contrast media: interactions with other drugs and clinical tests. Eur Radiol 15:1463\u20131468. DOI 10.1007\/s00330-004-2600-1","DOI":"10.1007\/s00330-004-2600-1"},{"key":"64_CR5","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1148\/radiology.175.3.2343107","volume":"175","author":"H Katayama","year":"1990","unstructured":"Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K (1990) Adverse reactions to ionic and nonionic contrast media: a report from the Japanese Committee on the Safety of Contrast Media. Radiology 175:621\u2013628","journal-title":"Radiology"},{"key":"64_CR6","doi-asserted-by":"crossref","unstructured":"Petersein J, Peters CR, Wolf M, Hamm B (2003) Results of the safety and efficacy of iobitridol in more than 61,000 patients. Eur Radiol 13:2006\u20132011. DOI 10.1007\/s00330-002-1583-z","DOI":"10.1007\/s00330-002-1583-z"},{"key":"64_CR7","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1088\/0034-4885\/63\/6\/201","volume":"63","author":"H Shinohara","year":"2000","unstructured":"Shinohara H (2000) Endohedral metallofullerenes. Rep Prog Phys 63:843\u2013892","journal-title":"Rep Prog Phys"},{"key":"64_CR8","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1021\/jp026867w","volume":"107","author":"Z Shi","year":"2003","unstructured":"Shi Z, Okazaki T, Shimada T, Sugai T, Suenaga T, Shinohara H (2003) Selective high-yield catalytic synthesis of terbium metallofullerenes and single-wall carbon nanotubes. J Phys Chem B 107:2485\u20132489","journal-title":"J Phys Chem B"},{"key":"64_CR9","doi-asserted-by":"crossref","unstructured":"Mikawa M, Kato H, Okumura M, Narazaki M, Kanazawa Y, Miwa N, Shinohara H (2001) Paramagnetic water-soluble metallofullerenes having the highest relaxivity for MRI contrast agents. Bioconjugate Chem 12:510\u2013514. DOI 10.1021\/bc000136m","DOI":"10.1021\/bc000136m"},{"key":"64_CR10","first-page":"854","volume":"25","author":"E Osawa","year":"1970","unstructured":"Osawa E (1970) Chohokozoku. Kagaku 25:854\u2013863 (in Japanese)","journal-title":"Kagaku"},{"key":"64_CR11","doi-asserted-by":"crossref","unstructured":"Kroto HW, Heath JR, O\u2019Brien SC, Curl RF, Smalley RF (1985) C60: Buckminsterfullerene. Nature 318:162\u2013163. DOI 10.1038\/318162a0","DOI":"10.1038\/318162a0"},{"key":"64_CR12","doi-asserted-by":"crossref","unstructured":"Kr\u00e4tschmer W, Fostiropoulos K, Lamb LD, Hufmman DR (1990) Solid C60: a new form of carbon. Nature 347:354\u2013358. DOI 10.1038\/347354a0","DOI":"10.1038\/347354a0"},{"key":"64_CR13","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0009-2614(90)87109-5","volume":"170","author":"W Kr\u00e4tschmer","year":"1990","unstructured":"Kr\u00e4tschmer W, Fostiropoulos K, Hufmman DR (1990) The infrared and ultraviolet absorption spectra of laboratory-produced carbon dust: evidence for the presence of the C60 molecule. Chem Phys Lett 170:167\u2013170","journal-title":"Chem Phys Lett"},{"key":"64_CR14","doi-asserted-by":"crossref","unstructured":"Takata M, Umeda B, Nishibori E, Sakata M, Saito Y, Ohno M, Shinohara H (1995) Confirmation by X-ray diffraction of the endohedral nature of the metallofullerene Y@C82. Nature 377:46\u201349. DOI 10.1038\/377046a0","DOI":"10.1038\/377046a0"},{"key":"64_CR15","first-page":"339","volume":"1","author":"N Tagmatarchis","year":"2001","unstructured":"Tagmatarchis N, Shinohara H (2001) Fullerenes in medical chemistry and their biological applications. Mini Rev Med Chem 1:339\u2013348","journal-title":"Mini Rev Med Chem"},{"key":"64_CR16","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/1074-5521(95)90219-8","volume":"2","author":"S Yamago","year":"1995","unstructured":"Yamago S, Tokuyama H, Nakamura E, Kikuchi K, Kananishi S, Sueki K, Nakahara H, Enomoto S, Ambe F (1995) In vivo biological behavior of a water-miscible fullerene: 14C labeling, absorption, distribution, excretion and acute toxicity. Chem Biol 2:385\u2013389","journal-title":"Chem Biol"},{"key":"64_CR17","doi-asserted-by":"crossref","unstructured":"Kato H, Kanazawa Y, Okumura M, Taninaka A, Yokawa T, Shinohara H (2003) Lanthanoid endohedral metallofullerenols for MRI contrast agents. J Am Chem Soc 125:4391\u20134397. DOI 10.1021\/ja027555+","DOI":"10.1021\/ja027555+"},{"key":"64_CR18","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1016\/S0960-894X(01)00583-2","volume":"11","author":"H Kato","year":"2001","unstructured":"Kato H, Yashiro A, Mizuno A, Nishida Y, Kobayashi K, Shinohara H (2001) Syntheses and biological evaluations of \u03b1-D-mannosyl[60]fullerenols. Bioorg Med Chem Lett 11:2935\u20132939","journal-title":"Bioorg Med Chem Lett"},{"key":"64_CR19","doi-asserted-by":"crossref","first-page":"6506","DOI":"10.1021\/ja00073a034","volume":"115","author":"HF Simon","year":"1993","unstructured":"Simon HF, Dianne LD, Rint PS, Gordana S, Fred W, George LK (1993) Inhibition of the HIV-1 protease by fullerene derivatives: model building studies and experimental verification. J Am Chem Soc 115:6506\u20136509","journal-title":"J Am Chem Soc"},{"key":"64_CR20","doi-asserted-by":"crossref","first-page":"4254","DOI":"10.1002\/1521-3773(20001201)39:23<4254::AID-ANIE4254>3.0.CO;2-O","volume":"39","author":"E Nakamura","year":"2000","unstructured":"Nakamura E, Isobe H, Tomita N, Sawamura M, Jinno S, Okayama H (2000) Functionalized fullerene as an artificial vector for transfection. Angew Chem Int Ed 39:4254\u20134257","journal-title":"Angew Chem Int Ed"},{"key":"64_CR21","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1002\/1521-3773(20010917)40:18<3364::AID-ANIE3364>3.0.CO;2-S","volume":"40","author":"H Isobe","year":"2001","unstructured":"Isobe H, Sugiyama S, Fukui K, Iwasawa Y, Nakamura E (2001) Atomic force microscope studies on condensation of plasmid DNA with functionalized fullerenes. Angew Chem Int Ed 40:3364\u20133367","journal-title":"Angew Chem Int Ed"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-005-0064-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-005-0064-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-005-0064-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T11:52:19Z","timestamp":1559044339000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-005-0064-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,13]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,4,10]]}},"alternative-id":["64"],"URL":"https:\/\/doi.org\/10.1007\/s00330-005-0064-6","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12,13]]}}}