{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T22:07:10Z","timestamp":1790460430794,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s00330-012-2527-x","type":"journal-article","created":{"date-parts":[[2012,6,30]],"date-time":"2012-06-30T14:43:14Z","timestamp":1341067394000},"page":"2790-2797","source":"Crossref","is-referenced-by-count":44,"title":["A comparison of MR elastography and 31P MR spectroscopy with histological staging of liver fibrosis"],"prefix":"10.1007","volume":"22","author":[{"given":"Edmund M.","family":"Godfrey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew N.","family":"Priest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse","family":"Joubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anant S.","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyree","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley S.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme J.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Allison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J. H.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander E. S.","family":"Gimson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Lomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,7,1]]},"reference":[{"key":"2527_CR1","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1002\/hep.20974","volume":"43","author":"SL Friedman","year":"2006","unstructured":"Friedman SL, Bansal MB (2006) Reversal of hepatic fibrosis \u2013 fact or fantasy? Hepatology 43:S82\u2013S88","journal-title":"Hepatology"},{"key":"2527_CR2","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.22742","volume":"49","author":"DC Rockey","year":"2009","unstructured":"Rockey DC, Caldwell SH, Goodman ZD, Nelson RC, Smith AD (2009) Liver biopsy. Hepatology 49:1017\u20131044","journal-title":"Hepatology"},{"key":"2527_CR3","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/gut.36.3.437","volume":"36","author":"IT Gilmore","year":"1995","unstructured":"Gilmore IT, Burroughs A, Murray-Lyon IM, Williams R, Jenkins D, Hopkins A (1995) Indications, methods, and outcomes of percutaneous liver biopsy in England and Wales: an audit by the British Society of Gastroenterology and the Royal College of Physicians of London. Gut 36:437\u2013441","journal-title":"Gut"},{"key":"2527_CR4","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1111\/j.1440-1746.2008.05718.x","volume":"24","author":"K Weigand","year":"2009","unstructured":"Weigand K (2009) Percutaneous liver biopsy: retrospective study over 15 years comparing 287 inpatients with 428 outpatients. J Gastroenterol Hepatol 24:792\u2013799","journal-title":"J Gastroenterol Hepatol"},{"key":"2527_CR5","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1111\/j.1572-0241.2002.06038.x","volume":"97","author":"A Regev","year":"2002","unstructured":"Regev A, Berho M, Jeffers LJ et al (2002) Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 97:2614\u20132618","journal-title":"Am J Gastroenterol"},{"key":"2527_CR6","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1056\/NEJM200102153440706","volume":"344","author":"AA Bravo","year":"2001","unstructured":"Bravo AA, Sheth SG, Chopra S (2001) Liver biopsy. N Engl J Med 344:495\u2013500","journal-title":"N Engl J Med"},{"key":"2527_CR7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jhep.2008.10.016","volume":"50","author":"S Bonekamp","year":"2009","unstructured":"Bonekamp S, Kamel I, Solga S, Clark J (2009) Can imaging modalities diagnose and stage hepatic fibrosis and cirrhosis accurately? J Hepatol 50:17\u201335","journal-title":"J Hepatol"},{"key":"2527_CR8","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1126\/science.7569924","volume":"269","author":"R Muthupillai","year":"1995","unstructured":"Muthupillai R, Lomas DJ, Rossman PJ, Greenleaf JF, Manduca A, Ehman RL (1995) Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science 269:1854\u20131857","journal-title":"Science"},{"key":"2527_CR9","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1148\/radiol.2402050606","volume":"240","author":"O Rouviere","year":"2006","unstructured":"Rouviere O, Yin M, Dresner MA et al (2006) MR elastography of the liver: preliminary results. Radiology 240:440\u2013448","journal-title":"Radiology"},{"key":"2527_CR10","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1148\/radiol.2523081817","volume":"253","author":"N Salameh","year":"2009","unstructured":"Salameh N, Larrat B, Abarca-Quinones J et al (2009) Early detection of steatohepatitis in fatty rat liver by using MR elastography. Radiology 253:90\u201397","journal-title":"Radiology"},{"key":"2527_CR11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ejrad.2007.06.004","volume":"66","author":"B Noren","year":"2008","unstructured":"Noren B, Dahlqvist O, Lundberg P et al (2008) Separation of advanced from mild fibrosis in diffuse liver disease using 31P magnetic resonance spectroscopy. Eur J Radiol 66:313\u2013320","journal-title":"Eur J Radiol"},{"key":"2527_CR12","doi-asserted-by":"crossref","first-page":"54","DOI":"10.7861\/clinmedicine.1-1-54","volume":"1","author":"SD Taylor-Robinson","year":"2001","unstructured":"Taylor-Robinson SD (2001) Applications of magnetic resonance spectroscopy to chronic liver disease. Clin Med 1:54\u201360","journal-title":"Clin Med"},{"key":"2527_CR13","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1053\/jhep.2003.50346","volume":"38","author":"CT Wai","year":"2003","unstructured":"Wai CT, Greenson JK, Fontana RJ et al (2003) A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 38:518\u2013526","journal-title":"Hepatology"},{"key":"2527_CR14","doi-asserted-by":"crossref","first-page":"S113","DOI":"10.1002\/hep.21046","volume":"43","author":"DC Rockey","year":"2006","unstructured":"Rockey DC, Bissell DM (2006) Noninvasive measures of liver fibrosis. Hepatology 43:S113\u2013120","journal-title":"Hepatology"},{"key":"2527_CR15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1136\/gut.2010.220863","volume":"60","author":"AC Cardoso","year":"2011","unstructured":"Cardoso AC, Carvalho-Filho RJ, Marcellin P (2011) Transient elastography in chronic viral hepatitis: a critical appraisal. Gut 60:759\u2013764","journal-title":"Gut"},{"key":"2527_CR16","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1016\/j.ultrasmedbio.2006.06.024","volume":"32","author":"H Maruyama","year":"2006","unstructured":"Maruyama H, Matsutani S, Okugawa H et al (2006) Microbubble disappearance-time is the appropriate timing for liver-specific imaging after injection of Levovist. Ultrasound Med Biol 32:1809\u20131815","journal-title":"Ultrasound Med Biol"},{"key":"2527_CR17","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2214\/ajr.176.3.1760667","volume":"176","author":"BE Beers Van","year":"2001","unstructured":"Van Beers BE, Leconte I, Materne R, Smith AM, Jamart J, Horsmans Y (2001) Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severity. AJR Am J Roentgenol 176:667\u2013673","journal-title":"AJR Am J Roentgenol"},{"key":"2527_CR18","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/MCG.0b013e3181a84b8d","volume":"44","author":"M Friedrich-Rust","year":"2010","unstructured":"Friedrich-Rust M, Muller C, Winckler A et al (2010) Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers. J Clin Gastroenterol 44:58\u201365","journal-title":"J Clin Gastroenterol"},{"key":"2527_CR19","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s11547-007-0149-1","volume":"112","author":"R Girometti","year":"2007","unstructured":"Girometti R, Furlan A, Bazzocchi M et al (2007) Diffusion-weighted MRI in evaluating liver fibrosis: a feasibility study in cirrhotic patients. Radiol Med 112:394\u2013408","journal-title":"Radiol Med"},{"key":"2527_CR20","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1148\/radiol.2463070077","volume":"246","author":"M Hagiwara","year":"2008","unstructured":"Hagiwara M, Rusinek H, Lee VS et al (2008) Advanced liver fibrosis: diagnosis with 3D whole-liver perfusion MR imaging\u2014initial experience. Radiology 246:926\u2013934","journal-title":"Radiology"},{"key":"2527_CR21","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S1361-8415(00)00039-6","volume":"5","author":"A Manduca","year":"2001","unstructured":"Manduca A, Oliphant TE, Dresner MA et al (2001) Magnetic resonance elastography: non-invasive mapping of tissue elasticity. Med Image Anal 5:237\u2013254","journal-title":"Med Image Anal"},{"key":"2527_CR22","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1006\/jmre.1997.1244","volume":"129","author":"L Vanhamme","year":"1997","unstructured":"Vanhamme L, van den Boogaart A, Van Huffel S (1997) Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 129:35\u201343","journal-title":"J Magn Reson"},{"key":"2527_CR23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF02668096","volume":"12","author":"A Naressi","year":"2001","unstructured":"Naressi A, Couturier C, Devos JM et al (2001) Java-based graphical user interface for the MRUI quantitation package. Magma 12:141\u2013152","journal-title":"Magma"},{"key":"2527_CR24","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0168-8278(95)80226-6","volume":"22","author":"K Ishak","year":"1995","unstructured":"Ishak K, Baptista A, Bianchi L et al (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22:696\u2013699","journal-title":"J Hepatol"},{"key":"2527_CR25","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.20701","volume":"41","author":"DE Kleiner","year":"2005","unstructured":"Kleiner DE, Brunt EM, Van Natta M et al (2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41:1313\u20131321","journal-title":"Hepatology"},{"key":"2527_CR26","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1148\/radiol.10092489","volume":"257","author":"P Asbach","year":"2010","unstructured":"Asbach P, Klatt D, Schlosser B et al (2010) Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography. Radiology 257:80\u201386","journal-title":"Radiology"},{"key":"2527_CR27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/nbm.1030","volume":"19","author":"L Huwart","year":"2006","unstructured":"Huwart L, Peeters F, Sinkus R et al (2006) Liver fibrosis: non-invasive assessment with MR elastography. NMR Biomed 19:173\u2013179","journal-title":"NMR Biomed"},{"key":"2527_CR28","doi-asserted-by":"crossref","first-page":"553","DOI":"10.2214\/AJR.10.4580","volume":"196","author":"Y Wang","year":"2011","unstructured":"Wang Y, Ganger DR, Levitsky J et al (2011) Assessment of chronic hepatitis and fibrosis: comparison of MR elastography and diffusion-weighted imaging. AJR Am J Roentgenol 196:553\u2013561","journal-title":"AJR Am J Roentgenol"},{"key":"2527_CR29","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.cgh.2007.06.012","volume":"5","author":"M Yin","year":"2007","unstructured":"Yin M, Talwalkar JA, Glaser KJ et al (2007) Assessment of hepatic fibrosis with magnetic resonance elastography. Clin Gastroenterol Hepatol 5:1207\u20131213, e1202","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2527_CR30","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/hep.23315","volume":"51","author":"JE Everhart","year":"2010","unstructured":"Everhart JE, Wright EC, Goodman ZD et al (2010) Prognostic value of Ishak fibrosis stage: findings from the hepatitis C antiviral long-term treatment against cirrhosis trial. Hepatology 51:585\u2013594","journal-title":"Hepatology"},{"key":"2527_CR31","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.1872-034X.2009.00500.x","volume":"39","author":"Y Nitta","year":"2009","unstructured":"Nitta Y, Kawabe N, Hashimoto S et al (2009) Liver stiffness measured by transient elastography correlates with fibrosis area in liver biopsy in patients with chronic hepatitis C. Hepatol Res 39:675\u2013684","journal-title":"Hepatol Res"},{"key":"2527_CR32","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1309\/D7AU-EYW7-4B6C-K08Y","volume":"114","author":"MJ O'Brien","year":"2000","unstructured":"O'Brien MJ, Keating NM, Elderiny S et al (2000) An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C. Am J Clin Pathol 114:712\u2013718","journal-title":"Am J Clin Pathol"},{"key":"2527_CR33","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1148\/radiol.2452061673","volume":"245","author":"L Huwart","year":"2007","unstructured":"Huwart L, Sempoux C, Salameh N et al (2007) Liver fibrosis: noninvasive assessment with MR elastography versus aspartate aminotransferase-to-platelet ratio index. Radiology 245:458\u2013466","journal-title":"Radiology"},{"key":"2527_CR34","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1053\/j.gastro.2008.03.076","volume":"135","author":"L Huwart","year":"2008","unstructured":"Huwart L, Sempoux C, Vicaut E et al (2008) Magnetic resonance elastography for the noninvasive staging of liver fibrosis. Gastroenterology 135:32\u201340","journal-title":"Gastroenterology"},{"key":"2527_CR35","volume-title":"Validity of a 3-D wave field model in MR elastography of the liver","author":"MGK Yin","year":"2009","unstructured":"Yin MGK, Talwalkar JA, Manduca A, Ehman RL (2009) Validity of a 3-D wave field model in MR elastography of the liver. ISMRM, Honolulu, p710"},{"key":"2527_CR36","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1053\/jhep.2003.50149","volume":"37","author":"AK Lim","year":"2003","unstructured":"Lim AK, Patel N, Hamilton G, Hajnal JV, Goldin RD, Taylor-Robinson SD (2003) The relationship of in vivo 31P MR spectroscopy to histology in chronic hepatitis C. Hepatology 37:788\u2013794","journal-title":"Hepatology"},{"key":"2527_CR37","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/s00330-004-2434-x","volume":"15","author":"B Noren","year":"2005","unstructured":"Noren B, Lundberg P, Ressner M, Wirell S, Almer S, Smedby O (2005) Absolute quantification of human liver metabolite concentrations by localized in vivo 31P NMR spectroscopy in diffuse liver disease. Eur Radiol 15:148\u2013157","journal-title":"Eur Radiol"},{"key":"2527_CR38","doi-asserted-by":"crossref","first-page":"G379","DOI":"10.1152\/ajpgi.00418.2003","volume":"287","author":"IR Corbin","year":"2004","unstructured":"Corbin IR, Ryner LN, Singh H, Minuk GY (2004) Quantitative hepatic phosphorus-31 magnetic resonance spectroscopy in compensated and decompensated cirrhosis. Am J Physiol Gastrointest Liver Physiol 287:G379\u2013384","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"2527_CR39","doi-asserted-by":"crossref","first-page":"6926","DOI":"10.3748\/wjg.v11.i44.6926","volume":"11","author":"M Dezortova","year":"2005","unstructured":"Dezortova M, Taimr P, Skoch A, Spicak J, Hajek M (2005) Etiology and functional status of liver cirrhosis by 31P MR spectroscopy. World J Gastroenterol 11:6926\u20136931","journal-title":"World J Gastroenterol"},{"key":"2527_CR40","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/02841859809172201","volume":"39","author":"K Kiyono","year":"1998","unstructured":"Kiyono K, Shibata A, Sone S et al (1998) Relationship of 31P MR spectroscopy to the histopathological grading of chronic hepatitis and response to therapy. Acta Radiol 39:309\u2013314","journal-title":"Acta Radiol"},{"key":"2527_CR41","first-page":"417","volume":"21","author":"DK Menon","year":"1995","unstructured":"Menon DK, Sargentoni J, Taylor-Robinson SD et al (1995) Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: biochemical basis of spectral appearances. Hepatology 21:417\u2013427","journal-title":"Hepatology"},{"key":"2527_CR42","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/hep.1840210228","volume":"21","author":"HN Wassenaer-van Hall van","year":"1995","unstructured":"van Wassenaer-van Hall HN, van der Grond J, van Hattum J, Kooijman C, Hoogenraad TU, Mali WP (1995) 31P magnetic resonance spectroscopy of the liver: correlation with standardized serum, clinical, and histological changes in diffuse liver disease. Hepatology 21:443\u2013449","journal-title":"Hepatology"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-012-2527-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-012-2527-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-012-2527-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T12:01:46Z","timestamp":1559044906000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-012-2527-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,1]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["2527"],"URL":"https:\/\/doi.org\/10.1007\/s00330-012-2527-x","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,1]]}}}