{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:20:54Z","timestamp":1783650054931,"version":"3.55.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T00:00:00Z","timestamp":1408060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Radiol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1007\/s00330-014-3359-7","type":"journal-article","created":{"date-parts":[[2014,8,13]],"date-time":"2014-08-13T23:05:30Z","timestamp":1407971130000},"page":"3142-3149","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":90,"title":["Anatomic variants of the pancreatic duct and their clinical relevance: an MR-guided study in the general population"],"prefix":"10.1007","volume":"24","author":[{"given":"Robin","family":"B\u00fclow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Thiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Thamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Messner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus M.","family":"Lerch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Mayerle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"V\u00f6lzke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Hosten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens-Peter","family":"K\u00fchn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,8,15]]},"reference":[{"key":"3359_CR1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00535-006-1920-0","volume":"42","author":"J Mayerle","year":"2007","unstructured":"Mayerle J, Lerch MM (2007) Is it necessary to distinguish between alcoholic and nonalcoholic chronic pancreatitis? J Gastroenterol 42:127\u2013130","journal-title":"J Gastroenterol"},{"key":"3359_CR2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1055\/s-0033-1335278","volume":"51","author":"MM Lerch","year":"2013","unstructured":"Lerch MM, Mayerle J (2013) 50 years of progress in pathophysiology, diagnosis and treatment of chronic pancreatitis. Z Gastroenterol 51:358\u2013362","journal-title":"Z Gastroenterol"},{"key":"3359_CR3","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/00006676-200311000-00002","volume":"27","author":"MC Dufour","year":"2003","unstructured":"Dufour MC, Adamson MD (2003) The epidemiology of alcohol-induced pancreatitis. Pancreas 27:286\u2013290","journal-title":"Pancreas"},{"key":"3359_CR4","first-page":"1467","volume":"89","author":"AB Lowenfels","year":"1994","unstructured":"Lowenfels AB, Maisonneuve P, Cavallini G et al (1994) Prognosis of chronic pancreatitis: an international multicenter study. International Pancreatitis Study Group. Am J Gastroenterol 89:1467\u20131471","journal-title":"Am J Gastroenterol"},{"key":"3359_CR5","first-page":"274","volume":"120","author":"G Kl\u00f6ppel","year":"1995","unstructured":"Kl\u00f6ppel G, Maillet B (1995) Development of chronic pancreatitis from acute pancreatitis: a pathogenetic concept. Zentralbl Chir 120:274\u2013277","journal-title":"Zentralbl Chir"},{"key":"3359_CR6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1148\/radiology.199.1.8633179","volume":"199","author":"PM Bret","year":"1996","unstructured":"Bret PM, Reinhold C, Taourel P et al (1996) Pancreas divisum: evaluation with MR cholangiopancreatography. Radiology 199:99\u2013103","journal-title":"Radiology"},{"key":"3359_CR7","first-page":"255","volume":"55","author":"Y Takehara","year":"1995","unstructured":"Takehara Y, Ichijo K, Tooyama N et al (1995) Enhanced delineation of the pancreatic duct in MR cholangiopancreatography (MRCP) with a combined use of secretin. Nihon Igaku Hoshasen Gakkai Zasshi 55:255\u2013256","journal-title":"Nihon Igaku Hoshasen Gakkai Zasshi"},{"key":"3359_CR8","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1067\/mge.2001.114784","volume":"53","author":"C Matos","year":"2001","unstructured":"Matos C, Metens T, Devi\u00e8re J et al (2001) Pancreas divisum: evaluation with secretin-enhanced magnetic resonance cholangiopancreatography. Gastrointest Endosc 53:728\u2013733","journal-title":"Gastrointest Endosc"},{"key":"3359_CR9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/s10620-011-1823-7","volume":"57","author":"P Mosler","year":"2012","unstructured":"Mosler P, Akisik F, Sandrasegaran K et al (2012) Accuracy of magnetic resonance cholangiopancreatography in the diagnosis of pancreas divisum. Dig Dis Sci 57:170\u2013174","journal-title":"Dig Dis Sci"},{"key":"3359_CR10","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1148\/radiology.214.3.r00mr24849","volume":"214","author":"R Manfredi","year":"2000","unstructured":"Manfredi R, Costamagna G, Brizi MG et al (2000) Severe chronic pancreatitis versus suspected pancreatic disease: dynamic MR cholangiopancreatography after secretin stimulation. Radiology 214:849\u2013855","journal-title":"Radiology"},{"key":"3359_CR11","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1007\/s00330-005-2819-5","volume":"15","author":"MA Bali","year":"2005","unstructured":"Bali MA, Sztantics A, Metens T et al (2005) Quantification of pancreatic exocrine function with secretin-enhanced magnetic resonance cholangiopancreatography: normal values and short-term effects of pancreatic duct drainage procedures in chronic pancreatitis. Initial results. Eur Radiol 15:2110\u20132121","journal-title":"Eur Radiol"},{"key":"3359_CR12","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1007\/s00261-006-9164-2","volume":"32","author":"MA Bali","year":"2007","unstructured":"Bali MA, Sontou R, Arvanitakis M et al (2007) Evaluation of the stimulating effect of a low dose of secretin compared to the standard dose on the exocrine pancreas with MRCP: preliminary results in normal subjects (MRCP quantification of secretin stimulation). Abdom Imaging 32:743\u2013748","journal-title":"Abdom Imaging"},{"key":"3359_CR13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1148\/radiology.218.1.r01ja2061","volume":"218","author":"JT Heverhagen","year":"2001","unstructured":"Heverhagen JT, M\u00fcller D, Battmann A et al (2001) MR hydrometry to assess exocrine function of the pancreas: initial results of noninvasive quantification of secretion. Radiology 218:61\u201367","journal-title":"Radiology"},{"key":"3359_CR14","doi-asserted-by":"crossref","unstructured":"Hegenscheid K, K\u00fchn J, V\u00f6lzke H, et al. (2009) Whole-body magnetic resonance imaging of healthy volunteers: pilot study results from the population-based SHIP study. Fortschr R\u00f6ntgenstr 181:748\u2013759","DOI":"10.1055\/s-0028-1109510"},{"key":"3359_CR15","doi-asserted-by":"crossref","unstructured":"V\u00f6lzke H, Alte D, Schmidt CO, et al. (2011) Cohort profile: the study of health in Pomerania. Int J Epidemiol 40:294\u2013307","DOI":"10.1093\/ije\/dyp394"},{"key":"3359_CR16","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.2214\/AJR.05.0774","volume":"187","author":"J Yu","year":"2006","unstructured":"Yu J, Turner MA, Fulcher AS, Halvorsen RA (2006) Congenital anomalies and normal variants of the pancreaticobiliary tract and the pancreas in adults: part 2, pancreatic duct and pancreas. AJR Am J Roentgenol 187:1544\u20131553","journal-title":"AJR Am J Roentgenol"},{"key":"3359_CR17","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1148\/rg.263055077","volume":"26","author":"MF Akisik","year":"2006","unstructured":"Akisik MF, Sandrasegaran K, Aisen AA et al (2006) Dynamic secretin-enhanced MR cholangiopancreatography. Radiographics 26:665\u2013677","journal-title":"Radiographics"},{"key":"3359_CR18","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1148\/radiology.203.2.9114101","volume":"203","author":"C Matos","year":"1997","unstructured":"Matos C, Metens T, Devi\u00e8re J et al (1997) Pancreatic duct: morphologic and functional evaluation with dynamic MR pancreatography after secretin stimulation. Radiology 203:435\u2013441","journal-title":"Radiology"},{"key":"3359_CR19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1148\/radiology.215.2.r00ma10358","volume":"215","author":"O Cappeliez","year":"2000","unstructured":"Cappeliez O, Delhaye M, Devi\u00e8re J et al (2000) Chronic pancreatitis: evaluation of pancreatic exocrine function with MR pancreatography after secretin stimulation. Radiology 215:358\u2013364","journal-title":"Radiology"},{"key":"3359_CR20","doi-asserted-by":"crossref","first-page":"102","DOI":"10.2214\/AJR.12.10271","volume":"202","author":"B Mensel","year":"2014","unstructured":"Mensel B, Messner P, Mayerle J et al (2014) Secretin-stimulated MRCP in volunteers: assessment of safety, duct visualization, and pancreatic exocrine function. AJR Am J Roentgenol 202:102\u2013108","journal-title":"AJR Am J Roentgenol"},{"key":"3359_CR21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159\u2013174","journal-title":"Biometrics"},{"key":"3359_CR22","unstructured":"Hoffmeister A, Mayerle J, Dathe K, et al. (2012) [Method report to the S3 guideline chronic pancreatitis: definition, etiology, diagnostics and conservative, interventional endoscopic and surgical therapy of the chronic pancreatitis]. In: Z Gastroenterol. pp 1225\u20131236"},{"key":"3359_CR23","first-page":"76","volume":"28","author":"B Stimec","year":"1996","unstructured":"Stimec B, Bulaji\u0107 M, Korneti V et al (1996) Ductal morphometry of ventral pancreas in pancreas divisum. Comparison between clinical and anatomical results. Ital J Gastroenterol 28:76\u201380","journal-title":"Ital J Gastroenterol"},{"key":"3359_CR24","first-page":"320","volume":"113","author":"H B\u00fchler","year":"1983","unstructured":"B\u00fchler H, Seefeld U, Deyhle P et al (1983) Clinical significance of pancreas divisum. Schweiz Med Wochenschr 113:320\u2013324","journal-title":"Schweiz Med Wochenschr"},{"key":"3359_CR25","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1136\/gut.25.7.756","volume":"25","author":"M Sarner","year":"1984","unstructured":"Sarner M, Cotton PB (1984) Classification of pancreatitis. Gut 25:756\u2013759","journal-title":"Gut"},{"key":"3359_CR26","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0033-8389(22)02117-0","volume":"27","author":"AT Axon","year":"1989","unstructured":"Axon AT (1989) Endoscopic retrograde cholangiopancreatography in chronic pancreatitis. Cambridge classification. Radiol Clin N Am 27:39\u201350","journal-title":"Radiol Clin N Am"},{"key":"3359_CR27","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1136\/gut.33.11.1566","volume":"33","author":"TN Walsh","year":"1992","unstructured":"Walsh TN, Rode J, Theis BA, Russell RC (1992) Minimal change chronic pancreatitis. Gut 33:1566\u20131571","journal-title":"Gut"},{"key":"3359_CR28","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/0016-5085(94)90553-3","volume":"107","author":"P Layer","year":"1994","unstructured":"Layer P, Yamamoto H, Kalthoff L et al (1994) The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology 107:1481\u20131487","journal-title":"Gastroenterology"},{"key":"3359_CR29","first-page":"118","volume":"13","author":"R Pezzilli","year":"2012","unstructured":"Pezzilli R (2012) Pancreas divisum and acute or chronic pancreatitis. JOP 13:118\u2013119","journal-title":"JOP"},{"key":"3359_CR30","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0016-5085(85)90193-3","volume":"89","author":"M Delhaye","year":"1985","unstructured":"Delhaye M, Engelholm L, Cremer M (1985) Pancreas divisum: congenital anatomic variant or anomaly? Contribution of endoscopic retrograde dorsal pancreatography. Gastroenterology 89:951\u2013958","journal-title":"Gastroenterology"},{"key":"3359_CR31","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00006676-199005000-00002","volume":"5","author":"JP Bernard","year":"1990","unstructured":"Bernard JP, Sahel J, Giovannini M, Sarles H (1990) Pancreas divisum is a probable cause of acute pancreatitis: a report of 137 cases. Pancreas 5:248\u2013254","journal-title":"Pancreas"},{"key":"3359_CR32","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2214\/ajr.173.1.10397125","volume":"173","author":"DE Morgan","year":"1999","unstructured":"Morgan DE, Logan K, Baron TH et al (1999) Pancreas divisum: implications for diagnostic and therapeutic pancreatography. AJR Am J Roentgenol 173:193\u2013198","journal-title":"AJR Am J Roentgenol"},{"key":"3359_CR33","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/1751-2980.12004","volume":"14","author":"T Rustagi","year":"2013","unstructured":"Rustagi T, Golioto M (2013) Diagnosis and therapy of pancreas divisum by ERCP: a single center experience. J Dig Dis 14:93\u201399","journal-title":"J Dig Dis"},{"key":"3359_CR34","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1038\/ajg.2012.302","volume":"107","author":"JA Nicholson","year":"2012","unstructured":"Nicholson JA, Johnstone M, Greenhalf W (2012) Divisum may be preserving pancreatic function in CFTR patients-but at a cost. Am J Gastroenterol 107:1758\u20131759","journal-title":"Am J Gastroenterol"},{"key":"3359_CR35","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/ajg.2011.430","volume":"107","author":"MJ DiMagno","year":"2012","unstructured":"DiMagno MJ, Dimagno EP (2012) Pancreas divisum does not cause pancreatitis, but associates with CFTR mutations. Am J Gastroenterol 107:318\u2013320","journal-title":"Am J Gastroenterol"},{"key":"3359_CR36","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/ajg.2011.424","volume":"107","author":"C Bertin","year":"2012","unstructured":"Bertin C, Pelletier A-L, Vullierme MP et al (2012) Pancreas divisum is not a cause of pancreatitis by itself but acts as a partner of genetic mutations. Am J Gastroenterol 107:311\u2013317","journal-title":"Am J Gastroenterol"},{"key":"3359_CR37","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/ajg.2009.611","volume":"105","author":"GM Cavestro","year":"2010","unstructured":"Cavestro GM, Zuppardo RA, Bertolini S et al (2010) Connections between genetics and clinical data: role of MCP-1, CFTR, and SPINK-1 in the setting of acute, acute recurrent, and chronic pancreatitis. Am J Gastroenterol 105:199\u2013206","journal-title":"Am J Gastroenterol"},{"key":"3359_CR38","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1097\/MCG.0b013e3181a4e772","volume":"43","author":"PK Garg","year":"2009","unstructured":"Garg PK, Khajuria R, Kabra M, Shastri SS (2009) Association of SPINK1 gene mutation and CFTR gene polymorphisms in patients with pancreas divisum presenting with idiopathic pancreatitis. J Clin Gastroenterol 43:848\u2013852","journal-title":"J Clin Gastroenterol"}],"container-title":["European Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-014-3359-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00330-014-3359-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00330-014-3359-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T22:59:25Z","timestamp":1689461965000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00330-014-3359-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,15]]},"references-count":38,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["3359"],"URL":"https:\/\/doi.org\/10.1007\/s00330-014-3359-7","relation":{},"ISSN":["0938-7994","1432-1084"],"issn-type":[{"value":"0938-7994","type":"print"},{"value":"1432-1084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,15]]}}}